Clinical Trials on Analgesics, Non-Narcotic in South Africa

Total 1373 results

Centre for the AIDS Programme of Research in South...
Columbia University

Completed

Promoting Engagement in the Drug Resistant TB/HIV Care Continuum in South Africa (PRAXIS)

Patient Non-compliance

South Africa
University of Cape Town

Completed

the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry (PERFUSION)

Acute Coronary Syndrome | Unstable Angina | ST Elevated Myocardial Infarction | Non ST Elevation Myocardial Infarction

South Africa
National Cancer Institute (NCI)

Unknown

Combination Chemotherapy in Patients With Advanced or Recurrent Mycosis Fungoides

Lymphoma

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Non-Communicable Diseases and Antiretroviral Therapy Outcomes in the RapIT Study Population (RapIT-NCD)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Antiretroviral Therapy, Highly Active

South Africa
Bio-Thera Solutions

Completed

A Comparative Study of BAT1706 and EU Avastin® in Patients With Advanced Non Squamous Non Small Cell Lung Cancer

Non-squamous Non-small Cell Lung Cancer

China, Mexico, South Africa, Turkey, Ukraine
University of Cape Town
Medtronic

Suspended

Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study (LCSD)

Dilated Cardiomyopathy | Ischemic Cardiomyopathy | Non-ischemic Cardiomyopathy

South Africa
University of Pretoria
Nestlè Nutrition Institute Africa; South African Sugar Association

Completed

Nutrition Education Intervention in Adults With Type 2 Diabetes Mellitus in a Resource Poor Setting

Diabetes Mellitus, Type II [Non-insulin Dependent Type] [NIDDM Type] Uncontrolled

South Africa
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
Pharmaceutical Project Solutions, Inc.

Completed

Topical Anesthetic for Procedures Through the Nose

Drug Reaction to Analgesic Nos

United States
University of Cape Town

Completed

Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline Protocol (HASS-2)

Hypertension | Metabolic Syndrome | Non-Compliance, Medication

South Africa
Medical University of South Carolina

Recruiting

RM1 Project 1 - tAN Naloxone

Analgesia

United States
European Organisation for Research and Treatment...

Completed

Temozolomide in Patients With Progressive or Recurrent Non-small Cell Lung Cancer

Lung Cancer

Italy, South Africa, United Kingdom, Netherlands, Poland
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; University of Stellenbosch

Withdrawn

Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women

HIV Infection | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | FIGO Stage IIB Cervix Carcinoma | FIGO Stage III Cervix Carcinoma | FIGO Stage IVA Cervix Carcinoma

South Africa, Zimbabwe
Pfizer

Completed

Trial Of AG-013736, Cisplatin, And Gemcitabine For Patients With Squamous Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung (NSCLC)

Ukraine, Poland, Romania, South Africa
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Optimizing the Use of Entonox® During Screening Colonoscopy

Analgesia | Colonoscopy | Bowel Cancer Screening | Entonox

United Kingdom
University of Adelaide

Unknown

An Assessment of Fentanyl Dose Requirements in Opioid-maintained Individuals (FEN001)

Opioid Dependence

Australia
Medical University of South Carolina

Completed

Impact of Dural Puncture Epidural Versus Traditional Lumbar Epidural on Onset of Labor Analgesia

Labor Pain | Labor Analgesia

United States
Prisma Health-Upstate
National Institute on Drug Abuse (NIDA); Clemson University

Recruiting

Development, Refinement, and Validation of a Peer Support Specialist Checklist for Individuals With Opioid Use Disorder / STAMPS: South Carolina Buprenorphine Treatment Initiation, Adherence, and Retention Utilizing Mobile Health Units and Peer Support Specialists

Opioid Use Disorder

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Impact of Lofexidine on Stress, Craving and Opioid Use

Opioid-use Disorder | Opiate Dependence

United States
The University of New South Wales

Unknown

Community Studies of Long Acting Buprenorphine (CoLAB) (CoLAB)

Opioid Dependence

Australia
Prisma Health-Upstate
Clemson University

Recruiting

CBT4CBT-Buprenorphine + Recovery Coach for Office-based Buprenorphine

Opioid-use Disorder

United States
Vega Therapeutics, Inc

Recruiting

Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease

Von Willebrand Diseases

United States, Austria, South Africa, United Kingdom
VA Office of Research and Development

Terminated

Transcranial Magnetic Stimulation (rTMS) as a Tool to Decrease Pain and Improve Functioning (TMS)

Opioid Use Disorder

United States
Smith & Nephew Pte Ltd

Active, not recruiting

Safety and Efficacy of the ANTHEM™ CR Total Knee System (Anthem CR)

Non-inflammatory Degenerative Joint Disease

India, Korea, Republic of, Italy, South Africa
Medical University of South Carolina

Completed

Program for Pain & Prescription Opioid Use in Pregnancy

Pain | Pregnancy | Opioid Abuse

United States
Checkpoint Therapeutics, Inc.

Terminated

Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab (CK-301) in First Line Metastatic Non-squamous Non-Small Cell Lung Cancer (CONTERNO)

Metastatic Non-squamous Non Small Cell Lung Cancer

Peru, Russian Federation, South Africa, New Zealand, Georgia, Thailand, Brazil, Malaysia
Medical University of South Carolina

Completed

Reducing Prescription Opioid Misuse: ROPEs Pilot Trial

Knowledge, Attitudes, Practice

United States
Agricultural University of Athens
Laikο General Hospital, Athens

Recruiting

Effects of Time-restricted Hypocaloric Diet in Patients With NAFLD

Non-Alcoholic Fatty Liver Disease

Greece
Hellenic Oncology Research Group

Unknown

NSCLC Heterogeneity in Early Stage Patients and Prediction of Relapse Using a Personalized "Liquid Biopsy"

Non Small Cell Lung Cancer

Greece
Millennium Pharmaceuticals, Inc.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

An Open-Label Study to Assess the Effect of CYP3A4 Induction on the Pharmacokinetics of VELCADE (Bortezomib)

Multiple Myeloma | Non-Hodgkin's Lymphoma

Israel, Italy, Poland, South Africa, United Kingdom
International Atomic Energy Agency

Completed

Optimization of Treatment of Advanced Nonsmall Cell Lung Cancer Using Radiotherapy and Chemotherapy

Non Small Cell Lung Cancer

Chile, China, Croatia, Egypt, India, Malaysia, Malta, Morocco, Pakistan, Panama, Peru, South Africa, Tunisia
Inipharm Australia Pty Ltd

Recruiting

A Study of INI-822 in Healthy Volunteers and Participants With Non-alcoholic Steatohepatitis (NASH) or Presumed NASH

Non-alcoholic Steatohepatitis

Australia
Philip Morris Products S.A.

Completed

Smoking Research Study

Smoking | Non-smoking

United Kingdom
Medical University of South Carolina
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC; National Drug...

Completed

Peer Intervention to Link Overdose Survivors to Treatment (PILOT) (PILOT)

Opioid Overdose

United States
Harokopio University
University of Novi Sad; National Research Council, Institute of Clinical Physiology...

Completed

Mastiha Treatment for Obese With NAFLD Diagnosis (MAST4HEALTH)

Non Alcoholic Fatty Liver Disease

Greece
New York State Psychiatric Institute
University of New Mexico

Completed

Culturally Centering Medications for Opioid Use Disorder With American Indian and Alaska Native Communities (CTN-0096)

Opioid-use Disorder

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Ketamine for the Treatment of Opioid Use Disorder and Depression

Depression | Opioid Abuse | Opioid-use Disorder

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

Chemotherapy Plus Radiation Therapy With or Without Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer

Lung Cancer

United States, South Africa
Leiden University Medical Center
Maag Lever Darm Stichting

Not yet recruiting

The Clock Thickens: Morning or Evening Training for the Treatment of NAFLD? (TikTac)

Non-Alcoholic Fatty Liver Disease

Netherlands
Member Companies of the Opioid PMR Consortium

Terminated

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse

United States
Prisma Health-Upstate
FAVOR (Faces and Voices of Recovery) OF GREENVILLE; South Carolina Department...

Completed

FAVOR Opioid Recovery Coaching Evaluation (FORCE)

Opioid-use Disorder | Opiate Overdose | Opiate Abuse

United States
Medical University of South Carolina

Terminated

Repetitive Transcranial Magnetic Stimulation for Opiate Use Disorder (ArTMS)

Chronic Pain | Opiate Dependence

United States
City of Hope Medical Center
OSI Pharmaceuticals

Completed

Erlotinib Hydrochloride With or Without Celecoxib in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Shanghai Henlius Biotech

Recruiting

HLX301 (TIGIT×PDL1 Bispecific) in Patients With Locally Advanced or Metastatic Solid Tumors

Non-small Cell Lung Cancer | Locally Advanced or Metastatic Solid Tumors

Australia
Medical University of South Carolina
South Carolina Clinical & Translational Research Institute (SCTR)

Completed

Developing rTMS Treatment Strategies for Pain in Opiate Dependence

Pain | Chronic Pain | Opioid Dependence | Opioid Use

United States
Yale University
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Coordinating Opioid Use Treatment Through Medical Management With Infection Treatment (Project COMMIT) (COMMIT)

Opioid-use Disorder

United States
ADC Therapeutics S.A.

Recruiting

A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

B-Cell Non-Hodgkin Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Relapsed B-Cell Non-Hodgkin Lymphoma

United States, Spain, Italy, United Kingdom, Belgium, Czechia
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Bortezomib and Gemcitabine in Treating Patients With Relapsed B-Cell Non-Hodgkin Lymphoma

Lymphoma

United States
Medical University of South Carolina

Recruiting

Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL

Chronic Lymphocytic Leukemia | B-cell Non Hodgkin Lymphoma

United States

Clinical Trials on Analgesics, Non-Narcotic in South Africa

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