Clinical Trials on Anaplastic Glioma of Brain in Germany

Total 159 results

Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma, Childhood and other conditions

United States, Italy, Japan, Germany, Spain, France, Canada, Australia, Brazil, Israel, Russian Federation, Argentina, United Kingdom, Finland, Belgium, Denmark, Czechia, Sweden, Switzerland, Netherlands
Nationwide Children's Hospital
Novartis

Not yet recruiting

Study of Ribociclib and Everolimus in HGG and DIPG

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Nationwide Children's Hospital

Not yet recruiting

Targeted Pediatric High-Grade Glioma Therapy

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma

United States, Australia, United Kingdom, Canada, Germany, Netherlands
University of Göttingen
Hannover Medical School; Deutsche Kinderkrebsstiftung

Recruiting

International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) (HIT-HGG-2013)

Diffuse Intrinsic Pontine Glioma | Gliomatosis Cerebri | Glioblastoma WHO Grade IV | Diffuse Midline Glioma Histone 3 K27M WHO Grade IV | Anaplastic Astrocytoma WHO Grade III

Germany
Martin-Luther-Universität Halle-Wittenberg
Merck KGaA, Darmstadt, Germany

Terminated

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents (HGG-CilMetro)

Gliomas

Germany
Nationwide Children's Hospital
Pfizer

Not yet recruiting

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | WHO Grade III Glioma | WHO Grade IV Glioma | Infant Type Hemispheric Glioma | Diffuse Midline Glioma, H3K27-altered

United States, Australia, Canada, Germany, Netherlands
University of Erlangen-Nürnberg Medical School

Completed

Immunophenotyping From Blood of Patients With Malignant Gliomas

Glioblastoma Multiforme | Anaplastic Astrocytoma

Germany
INSYS Therapeutics Inc

Completed

Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma

United States, Germany, Israel
Novartis Pharmaceuticals

Recruiting

Pediatric Long-Term Follow-up and Rollover Study

Glioblastoma | Astrocytoma | Anaplastic Astrocytoma | Neurofibromatosis Type 1 | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma... and other conditions

United States, Belgium, Spain, Denmark, Germany, Czechia, Italy, Australia, Russian Federation, France, Netherlands, Japan, Canada, Finland, Sweden, United Kingdom, Argentina, Israel, Brazil
University Hospital Tuebingen

Recruiting

Multi Peptide Vaccination With XS15 in Addition to Standard Postoperative Radiation Therapy and Temozolomide Chemotherapy in Newly Diagnosed Glioblastoma (GLIO-XS15)

Glioblastoma Multiforme of Brain

Germany
Neuro-Oncology Working Group of the German Cancer...
Charite University, Berlin, Germany; University of Zurich; University Hospital... and other collaborators

Completed

Randomized Phase III Study of Sequential Radiochemotherapy of Anaplastic Glioma With PCV or Temozolomide (NOA-04)

Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma

Germany
SonoClear AS

Recruiting

SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue

Glioblastoma | High Grade Glioma | Low-grade Glioma | Brain Tumour

Germany, Slovakia, Italy
European Organisation for Research and Treatment...
Tragara Pharmaceuticals, Inc.

Completed

Study of TG02 in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma (STEAM)

Glioblastoma | Astrocytoma, Grade III

France, Austria, Germany, Netherlands, Switzerland
Johann Wolfgang Goethe University Hospital

Unknown

Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery (IMAGER)

Glioma | Glioblastoma | Primary Malignant Neoplasm of Nervous System | Metastasis

Germany
Heinrich-Heine University, Duesseldorf
Johann Wolfgang Goethe University Hospital

Unknown

Spinal Motor Evoked Potentials in Brain Surgery

Glioma | Brain Tumor

Germany
Heidelberg University

Completed

Phase III Trial of Primary Radio- or Chemotherapy in Malignant Astrocytoma of the Elderly (Methusalem)

Glioblastoma | Anaplastic Astrocytoma

Germany, Switzerland
Orbus Therapeutics, Inc.

Active, not recruiting

Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients (STELLAR)

Anaplastic Astrocytoma | Recurrent Anaplastic Astrocytoma

United States, United Kingdom, France, Canada, Italy, Germany, Netherlands, Belgium
University of Regensburg

Completed

Shortening of the Twitch Stabilization Period by Tetanic Stimulation in Acceleromyography in Children and Young Adults (STSTS)

Train-of-Four-Monitoring

Germany
Isarna Therapeutics GmbH

Completed

Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma

Glioblastoma | Anaplastic Astrocytoma

Germany, Austria, Georgia, India, Israel, Russian Federation
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302) (RECSUR)

Glioblastoma | Glioblastoma Multiforme | Recurrent Glioblastoma | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain | Astrocytoma of Brain | Astrocytoma, Malignant

United States, Germany, Netherlands, Switzerland, Belgium
BDH-Klinik Hessisch Oldendorf

Recruiting

Effectiveness of Music Therapy on Level of Consciousness

Traumatic Brain Injury | Neurologic Disorder | Disorder of Consciousness

Germany
Nationwide Children's Hospital

Recruiting

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

High Grade Glioma | Diffuse Intrinsic Pontine Glioma

United States, Australia, Canada, Germany
European Organisation for Research and Treatment...
Medical Research Council

Completed

Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma

Brain and Central Nervous System Tumors

France, Switzerland, Netherlands, United Kingdom, Belgium, Germany, Italy, Sweden, Finland, Portugal, Austria, Hungary
Rigel Pharmaceuticals
Nationwide Children's Hospital

Not yet recruiting

Study of Olutasidenib and Temozolomide in HGG

Astrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditions

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Technical University of Munich
Charite University, Berlin, Germany; Evangelisches Krankenhaus Bielefeld gGmbH

Completed

nTMS for Motor Mapping of Rolandic Lesions (Motorstim)

Glioma | Brain Metastases

Switzerland, Germany, Italy
Isarna Therapeutics GmbH

Terminated

Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma (SAPPHIRE)

Glioblastoma | Anaplastic Astrocytoma

Spain, Taiwan, Korea, Republic of, United States, Hungary, Germany, Argentina, Brazil, India, Canada, Austria, France, Mexico, Poland, Russian Federation, United Kingdom
BDH-Klinik Hessisch Oldendorf

Recruiting

Prognostic Factors to Regain Consciousness

Stroke | Traumatic Brain Injury | Neurologic Disorder | Disorder of Consciousness | Hypoxic-Ischemic Encephalopathy

Germany
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202) (RESBIOP)

Glioblastoma | Glioblastoma Multiforme | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain

United States, Belgium, Switzerland, Germany, Netherlands
PD Dr. Martin Glas

Unknown

Dovitinib (TKI258) in the Treatment of Patients With Relapsed Glioblastoma (TKI258)

First or Second Recurrence of Glioblastoma

Germany
Technische Universität Dresden

Not yet recruiting

Automated Screening for Clinically Ascertained Loss of Cerebral Functions (DETECT-IVE)

Irreversible Loss of Brain Function (ILBF)

Germany
Erasmus Medical Center
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma (RECMAP)

Glioblastoma | Brain Neoplasms | Recurrent Glioblastoma | Recurrent Adult Brain Tumor | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme of Brain | Brain Neoplasms, Adult, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Switzerland, Belgium, Netherlands
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) (SUPRAMAX)

Glioblastoma | Brain Neoplasms | Astrocytoma, Grade III | High-grade Glioma | Astrocytoma, Grade IV | Glioblastoma, IDH-mutant | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Brain Neoplasm, Primary | Brain Neoplasm, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Belgium, Switzerland, Netherlands
Charite University, Berlin, Germany

Withdrawn

Influence of tDCS on Cortical Plasticity in Patients With Dementia of the Alzheimer Type

Dementia of Type Alzheimer

Germany
University Hospital Tuebingen

Completed

Vegetative Monitoring During Brainstem-associated Surgery

Brain Tumor, Recurrent | Vestibular Schwannoma | Brainstem Glioma | Brainstem Neoplasm

Germany
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Setting Benchmarks for Microsurgical Clipping of Unruptured Intracranial Aneurysms

Aneurysm | Aneurysm, Intracranial | Aneurysm Cerebral | Aneurysm, Brain | Aneurysm of Cerebral Artery

Germany
UCB Biopharma SRL

Active, not recruiting

A Study to Test the Efficacy, Safety, and Pharmacokinetics of Rozanolixizumab in Adult Study Participants With Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis

Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis

United States, Australia, Belgium, France, Germany, Italy, Netherlands, Spain, United Kingdom
University of Leipzig
German Center for Neurodegenerative Diseases (DZNE)

Completed

Talking Time: Telephone Support Groups for Informal Caregivers of People With Dementia

Caregivers of People With Dementia

Germany
Ludwig-Maximilians - University of Munich
Therapiezentrum Burgau

Completed

Erigo®Pro Coma Outcome Study - Study on the Effectiveness of a Robotic Tilt Table Device for Recovery of Consciousness (EriCOS)

Brain Injuries | Disorders of Consciousness

Germany
European Organisation for Research and Treatment...

Recruiting

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study (LEGATO)

First Progression of Glioblastoma

Netherlands, Austria, Germany
University of Rostock
DZNE, German Center for Neurodegenerative Disorders, Germany

Unknown

Effect of Cognitive Intervention in Alzheimer's Disease (AD) on Functional Cortical Networks in fMRI (ECIF)

Dementia of the Alzheimer Type

Germany
University Hospital, Bonn

Completed

Auditory Beat Stimulation and Behavioural Variant of Frontotemporal Dementia

Anxiety | bvFTD

Germany
University of Rostock
German Center for Neurodegenerative Diseases (DZNE)

Completed

Short-term Caregiver Psychotherapy

Caregiver Burden of People With Dementia

Germany
Universitätsklinikum Hamburg-Eppendorf

Completed

Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Brain and Central Nervous System Tumors

Germany
University Medicine Greifswald

Completed

Trajectories of Post-stroke Multidimensional Health (NeuroAdapt)

Transient Ischemic Attack | Aging | Stroke, Ischemic | Adaptation, Psychological | Mental Health Impairment | Sense of Coherence | Adjustment | Self-Rated Health

Germany
Ludwig-Maximilians - University of Munich

Recruiting

Registry Study for the Observation of Patients With ESUS/Cryptogenic Stroke (Catch-up-ESUS)

Embolic Stroke of Undetermined Source

Germany
University Hospital of Cologne
Hannover Medical School; Boston Scientific Corporation; University Hopsital Schleswig... and other collaborators

Active, not recruiting

Effect of DBS on Quality of Life in Dyskinetic Cerebral Palsy (STIM-CP)

Dyskinetic Cerebral Palsy Due to Perinatal Hypoxia

Germany
Novartis Pharmaceuticals

Recruiting

Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.

Brain Neoplasms | Glioblastoma Multiforme | Gastroesophageal Adenocarcinoma | Pancreatic Ductal Adenocarcinoma

Germany, United States, France
Societe Internationale d'Oncologie Pediatrique

Unknown

Carboplatin Plus Vincristine in Treating Children and Adolescents With Low Grade Glioma

Brain and Central Nervous System Tumors

United Kingdom, Italy, Germany
Universitätsklinikum Hamburg-Eppendorf

Suspended

International HIT-MED Registry (I-HIT-MED)

Childhood Brain Tumor

Germany
Ruhr University of Bochum

Completed

Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke

Test the Efficacy of Antiplatelet Regimes in Acute Stroke

Germany

Clinical Trials on Anaplastic Glioma of Brain in Germany

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