Clinical Trials on Aseptic Inflammation in United States

Total 2263 results

Viome

Terminated

Systems Biology of Gastrointestinal and Related Diseases

Obesity | Gastritis | Irritable Bowel Syndrome | Gastric Cancer | Esophageal Cancer | Gastro Esophageal Reflux | Crohn Disease | GERD | NAFLD | Ulcerative Colitis | Eosinophilic Esophagitis | Gastric Ulcer | Duodenal Ulcer | Barrett Esophagus | Intestinal Metaplasia | Colon Polyp | Lymphocytic Colitis | IBS | SIBO | Gallstone Disease | Microscopic Colitis and other conditions

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Early-Onset Sepsis Surveillance Study (EOS)

Sepsis | Gram-Negative Bacterial Infections | Gram-Positive Bacterial Infections | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Durata Therapeutics Inc., an affiliate of Allergan...

Completed

Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Abscess | Cellulitis | Surgical Site Infection | Wound Infection

United States, Bulgaria, Croatia, Estonia, Georgia, Hungary, Latvia, Romania, Russian Federation, Serbia, South Africa, Ukraine
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Hodgkin Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myelodysplastic/Myeloproliferative Neoplasm | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Cytomegalovirus... and other conditions

United States
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Completed

Improving Safety of Diagnosis and Therapy in the Inpatient Setting (PSLL2-0)

Pneumonia | Sepsis | Delirium | Confusion | Hip Pain Chronic | Hypoxia | Back Pain | Vomiting | Abdominal Pain | Diarrhea | Cough | Asthma | Chest Pain | Neck Pain | Fever | Cellulitis | Syncope | Headache | Deep Vein Thrombosis | Venous Thromboembolism | Soft Tissue Infections | Failure to Thrive | COPD | Pulmonary Embolism | Dyspnea | Leg Pain | Mental... and other conditions

United States
AstraZeneca

Completed

Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome

Zollinger-Ellison Syndrome

United States, France
ContraFect

Terminated

Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)

Staphylococcus Aureus Bacteremia | Staphylococcus Aureus Endocarditis

United States
University of Oxford
Barts and the London School of Medicine and Dentistry; Queen Mary University... and other collaborators

Unknown

Functional Genomic Influences on Disease Progression and Outcome in Sepsis (GAinS)

Pneumonia | Peritonitis

United Kingdom
Pharmacia

Completed

A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDS

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Belfast Health and Social Care Trust
Queen's University, Belfast; Royal College of Emergency Medicine; Pediatric Emergency... and other collaborators

Completed

Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA. (PIC)

Sepsis | Meningitis, Meningococcal | Meningitis | Meningococcal Infections | Meningococcal Disease | Meningococcal Sepsis

United Kingdom
Northwell Health
Pediatric Surgical Research Collaborative

Active, not recruiting

MIPE for Pilonidal Disease

Pilonidal Disease | Pilonidal Sinus Without Abscess | Pilonidal Cyst/Fistula | Pilonidal Cyst Without Abscess | Pilonidal Cyst and Sinus Without Abscess | Pilonidal Abscess | Pilonidal Sinus With Abscess | Pilonidal Dimple With Abscess | Pilonidal Fistula With Abscess | Pilonidal Sinus Infected | Pilonidal... and other conditions

United States
Durata Therapeutics Inc., an affiliate of Allergan...

Completed

Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Abscess | Cellulitis | Surgical Site Infection | Wound Infection

United States, Bulgaria, Estonia, Hungary, Israel, Korea, Republic of, Latvia, Lithuania, Romania, Russian Federation, Slovakia, South Africa, Taiwan, Ukraine
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Canakinumab Treatment for CRS in Participants With COVID-19-induced Pneumonia (CAN-COVID)

Cytokine Release Syndrome (CRS) in Patients With COVID-19-induced Pneumonia

Spain, United States, United Kingdom, Russian Federation, Italy, France
King's College London

Completed

International T1 Multicentre CMR Outcome Study (T1-CMR)

Coronary Artery Disease | Fibrosis | Heart Failure | Inflammation | Chronic Kidney Diseases | Cardiomyopathy

United Kingdom, Germany, Australia
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes. (ELICIT)

HIV Infections | Cytomegalovirus | CMV

United States
Atara Biotherapeutics
Merck Sharp & Dohme LLC

Terminated

Tabelecleucel in Combination With Pembrolizumab in Subjects With Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)

Nasopharyngeal Carcinoma | Nasopharyngeal Neoplasms | Epstein-Barr Virus Infections | Epstein-Barr Viraemia | Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)

United States
Anahuac University

Completed

Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III

Inflammation | Hypertension | Obesity | Diabetes Mellitus | Mortality | Overweight | COVID19 | Oxygen Saturation

Mexico
Sanofi
Regeneron Pharmaceuticals

Completed

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation (BOREAS)

Chronic Obstructive Pulmonary Disease

Spain, Argentina, China, Mexico, Canada, Ukraine, Israel, Italy, Czechia, Korea, Republic of, Bulgaria, Chile, Denmark, Finland, Germany, Hungary, Japan, Poland, Romania, Russian Federation, Slovakia, Sweden, Turkey, United States
Pharmacia

Completed

A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Abivax S.A.

Terminated

ABX464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19 (Mir-Age)

COVID-19

Spain, Belgium, United Kingdom, Germany, France, Brazil, Italy, Mexico
Targanta Therapeutics Corporation

Completed

A Study for Patients With Complicated Skin and Skin Structure Infections (SIMPLIFI)

Wounds and Injuries | Streptococcal Infections | Abscess | Cellulitis | Staphylococcal Skin Infections

United States, Australia, India, Italy, Romania, Ukraine
Novartis Pharmaceuticals
Incyte Corporation

Completed

Study to Assess the Efficacy and Safety of Ruxolitinib in Patients With COVID-19 Associated Cytokine Storm (RUXCOVID)

Cytokine Storm (Covid-19)

United States, Colombia, Turkey, Spain, United Kingdom, Germany, Peru, Russian Federation, Brazil, France, Mexico, Argentina
Janssen Research & Development, LLC

Terminated

A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections

Rupture | Abdominal Pain | Appendicitis | Peritonitis | Abdominal Abscess | Infection | Ileus | Intestinal Perforation | Abdomen, Acute | Abscess, Intra-Abdominal

United States, Argentina, Colombia, Chile, Panama, Lithuania, Latvia, Brazil
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Chronic Obstructive Pulmonary Disease

Greece, Belgium, Spain, Argentina, Hungary, South Africa, United Kingdom, France, Latvia, Germany, Netherlands, Russian Federation, Ukraine, United States, Australia, Brazil, Bulgaria, Canada, Chile, Colombia, Czechia, Lithuania, Me... and more
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Canada
University of Nottingham
UK Dermatology Clinical Trials Network; Action Medical Research

Completed

RCT to Investigate if Prophylactic Antibiotics Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg (PATCH1)

Cellulitis/Erysipelas of the Leg

United Kingdom, Ireland
Atox Bio Ltd

Terminated

Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury

Acute Kidney Injury | Peritonitis | Necrotizing Soft Tissue Infection

United States, France
Avita Medical

Completed

RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction

Cellulitis | Surgical Wound | Skin Cancer | Infection | Crush Injuries | Degloving Injuries | Gun Shot Wound | Necrotizing Fasciitis | Laceration of Skin | Full-thickness Skin Defects

United States
Stiefel, a GSK Company
GlaxoSmithKline

Completed

Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA

Skin Infections, Bacterial

United States
University of Cambridge
Lund University; GE Healthcare; Cambridge University Hospitals NHS Foundation... and other collaborators

Recruiting

PET Imaging of Inflammation and Lipid Lowering Study (PIILL)

Atherosclerosis | Carotid Artery Plaque | Hypercholesterolemia | Hypercholesterolemia, Familial

United Kingdom
Rempex (a wholly owned subsidiary of Melinta Therapeutics...

Completed

Study of Cases of Serious Infections Due to Carbapenem-Resistant Enterobacteriaceae

Bacteremia | Acute Pyelonephritis | Ventilator-associated Bacterial Pneumonia | Hospital Acquired Bacterial Pneumonia | Urinary Tract Infection, Complicated

Italy, United States, Greece, United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Breast-implant ASsocIated anaplastIc Large Cell Lymphoma and CApsular Contracture (BASILICA)

Breast Implant-Associated Anaplastic Large Cell Lymphoma | Breast Implant; Complications | Capsular Contracture, Implant

United Kingdom
Michael Morowitz
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

NICU Antibiotics and Outcomes Trial (NANO)

Microbial Colonization | Late-Onset Neonatal Sepsis | Necrotizing Enterocolitis of Newborn | Extreme Prematurity | Death; Neonatal | Early-Onset Neonatal Sepsis

United States, Canada
AbbVie

Completed

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

Bacterial Infections | Staphylococcal Skin Infections | Methicillin-Resistant Staphylococcus Aureus

United States, Bulgaria, Chile, Colombia, Georgia, Greece, Guatemala, Latvia, Mexico, Panama, Spain, Ukraine
AM-Pharma

Terminated

(Revival) Study to Investigate the Efficacy and Safety of Alkaline Phosphatase in Patients With Sepsis-Associated AKI

Acute Kidney Injury Due to Sepsis

Belgium, Spain, United States, Austria, Denmark, France, United Kingdom, Finland, New Zealand, Australia, Germany, Canada, Netherlands, Ireland, Japan
Redx Pharma Plc
Simbec Research

Completed

A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

Liver Diseases | Fibrosis | Kidney Diseases | Inflammation | Idiopathic Pulmonary Fibrosis | Non-alcoholic Steatohepatitis

United Kingdom
Novo Nordisk A/S

Completed

Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition (RESCUE)

Inflammation | Chronic Kidney Diseases

United States
Altor BioScience
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome

Sepsis | Acute Respiratory Distress Syndrome | Acute Lung Injury

United States
Cidara Therapeutics Inc.

Recruiting

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation (ReSPECT)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis | Invasive Fungal Disease | Pneumocystis | Mold Infection | Prophylaxis of Invasive Fungal Infections | Aspergillus

United States, Germany, France, Belgium, Canada, Italy, Spain, United Kingdom, Turkey, Switzerland
National Institute of Allergy and Infectious Diseases...
Andrulis Pharmaceuticals

Completed

Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection

HIV Infections | Stomatitis, Aphthous

United States, Puerto Rico
St George's, University of London
Assistance Publique - Hôpitaux de Paris; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Recruiting

Serocorrelate of Protection Against GBS (PREPARE WP3)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

France, Italy, Malawi, Netherlands, Uganda, United Kingdom
AtheroGenics

Unknown

ARISE - Aggressive Reduction of Inflammation Stops Events

Myocardial Infarction | Coronary Artery Disease | Atherosclerosis | Unstable Angina

Canada, United States, United Kingdom, South Africa
Maastricht University Medical Center
Charles University, Czech Republic; Karolinska University Hospital; Hospices... and other collaborators

Recruiting

European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO (EuroECMO-COVID)

Septic Shock | Extracorporeal Membrane Oxygenation | COVID | SARS-CoV-2 | Cardiogenic Shock | ARDS, Human | Refractory Hypoxemia

Spain, Germany, Netherlands, France, Sweden, Belgium, Austria, Portugal, Poland, United Kingdom, Italy, Lithuania, Czechia, Denmark, Greece, Hungary, Israel, Russian Federation, Switzerland
Novartis

Completed

Efficacy and Safety of ACZ885 in Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Cryopyrin-Associated Periodic Syndromes | Neonatal Onset Multisystem Inflammatory Disease | Muckle Wells Syndrome

United States, Germany, Italy, Spain, United Kingdom, Turkey, France, Belgium, India
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)

Cholecystitis | Appendicitis | Diverticulitis | Intra-Abdominal Abscess | Intra-Abdominal Infection | Peritonitis

Italy, Spain, China, France, Switzerland, Australia, Denmark, Finland, Germany, Greece, Hong Kong, India, Philippines, Portugal, Saudi Arabia, South Africa, Taiwan, Turkey, United Kingdom
Global Healthy Living Foundation
University of Alabama at Birmingham

Recruiting

PatientSpot Formerly Known as ArthritisPower (GHLF)

Heart Failure | Stroke | Epilepsy | Multiple Sclerosis | Obesity | Diabetes | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Peripheral Arterial Disease | Inflammatory Bowel Diseases | Amyotrophic Lateral Sclerosis | Psoriasis | Asthma | Muscular Dystrophy | Fibromyalgia | Alzheimer... and other conditions

United States
Massachusetts General Hospital

Completed

Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery (ASTER)

Sepsis | Critical Illness | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
Entasis Therapeutics

Completed

Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex (ATTACK)

Bacteremia | Ventilator-associated Bacterial Pneumonia | Acinetobacter Baumannii-calcoaceticus Complex | Hospital-acquired Bacterial Pneumonia | Colistin Resistant ABC

United States, Belarus, Brazil, China, Greece, Hungary, India, Israel, Korea, Republic of, Lithuania, Mexico, Peru, Puerto Rico, Russian Federation, Taiwan, Thailand, Turkey
Heart of England NHS Trust
University of Warwick; University of Birmingham

Completed

Chest Wall Motion Analysis in Disease (CWM)

Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Surgery | Cystic Fibrosis | Mesothelioma | Empyema, Pleural | Pectus Excavatum | Pectus Carinatum

United Kingdom

Clinical Trials on Aseptic Inflammation in United States

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Portugal

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations