Clinical Trials on BK Virus Infection in South Africa

Total 3409 results

University of Cape Town
London School of Hygiene and Tropical Medicine; Johns Hopkins University; Imperial... and other collaborators

Completed

Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons (HAART-IPT)

HIV Infections | Tuberculosis | Latent Tuberculosis Infection

South Africa
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition

HIV Infections | Bacterial Vaginosis

South Africa
Institut Pasteur
Institut Pasteur de Bangui

Active, not recruiting

A One Health Study of Monkeypox Human Infection (AFRIPOX)

Monkeypox Virus Infection

Central African Republic
International Partnership for Microbicides, Inc.

Withdrawn

A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa

HIV Infections

South Africa, Kenya, Malawi
Minervax ApS
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Study of a Group B Streptococcus Vaccine in Pregnant Women Living With HIV and in Pregnant Women Who do Not Have HIV

Group B Streptococcal Infection

South Africa, Uganda
Alvea Holdings, LLC

Completed

Safety, Tolerability and Immunogenicity of Alveavax-v1.2, a BA.2/Omicron-optimized, DNA Vaccine for COVID-19 Prevention

Sars-CoV-2 Infection

South Africa
Desmond Tutu HIV Foundation
Karolinska Institutet; University of North Carolina, Chapel Hill; ViiV Healthcare and other collaborators

Completed

Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People (BUDDY)

HIV Infections | Covid19 | Health Care Utilization | Gender-based Violence

South Africa
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Interferon-Gamma on Cavitary Pulmonary Tuberculosis in the Lungs

Tuberculosis | AIDS-related Complex

United States, South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions

Infections, Bacterial

South Africa
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaborators

Active, not recruiting

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

HIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial Neoplasia

Uganda, Kenya, Zimbabwe, South Africa, Malawi
Chris Hani Baragwanath Academic Hospital

Terminated

High Flow Oxygen Therapy vs Standard Care in Infants With Viral Bronchiolitis

Bronchiolitis, Viral

South Africa
Population Council
United States Agency for International Development (USAID); Bill and Melinda...

Completed

Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission

HIV Infections | Sexually Transmitted Diseases | AIDS | HIV Seroconversion

South Africa
Janssen Research & Development, LLC

Completed

A Study to Assess the Acceptability of the Darunavir/Cobicistat (DRV/COBI) Fixed-dose Combination (FDC) Tablet in Human Immunodeficiency Virus (HIV)-1 Infected Children

Human Immunodeficiency Virus (HIV)

United States, Spain, South Africa
Willem Daniel Francois Venter
Bill and Melinda Gates Foundation

Completed

Dose Optimisation of Stavudine for the Treatment of HIV Infection (D4T)

Human Immunodeficiency Virus | Acquired Immune Deficiency Syndrome

South Africa, India, Uganda
University of Oxford
Bill and Melinda Gates Foundation; Medical Research Council, South Africa; University... and other collaborators

Unknown

COVID-19 Vaccine (ChAdOx1 nCoV-19) Trial in South African Adults With and Without HIV-infection

Coronavirus

South Africa
Ark Biosciences Inc.

Terminated

A Study of AK0529 in Infants Hospitalized With RSV

Respiratory Syncytial Virus Infections

Australia
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
Centre for the AIDS Programme of Research in South...

Completed

A Study to Compare Three Existing Starting Points of Anti-Retroviral Therapy (ART) Initiation in HIV/Tuberculosis (TB) Co-infected Patients (SAPIT)

HIV Infections | Tuberculosis

South Africa
FHI 360
United States Agency for International Development (USAID); Makerere University and other collaborators

Completed

Interactions Between Antiretrovirals (ARVs) and Combined Oral Contraceptives (COCs)

HIV Infections | HIV/AIDS

South Africa, Uganda
University of Pretoria

Not yet recruiting

Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection

Prevention of Postpartum Sepsis

South Africa
Centers for Disease Control and Prevention
United States Agency for International Development (USAID); Bill and Melinda... and other collaborators

Unknown

Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

Sepsis | Infant, Newborn, Diseases | Puerperal Infection

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Females - A Sub-study of HPTN 084

HIV Infections

Zimbabwe, South Africa, Uganda
Medical University of Graz
Lagos State University; Walter Sisulu University; Management Sciences for Health and other collaborators

Enrolling by invitation

Effects of COVID-19 on Endothelium in HIV-Positive Patients in Sub-Saharan Africa (ENDOCOVID)

Covid19 | Hiv | ART

Nigeria, South Africa
Professor Francois Venter

Recruiting

ADORE: Efficacy of DORavirine in Adults Living With HIV Experiencing Virological Failure on First-line Efavirenz-based Antiretroviral Therapy With NNRTI Resistance (ADORE)

HIV-1-infection

South Africa
Professor Francois Venter

Completed

ADVANCE Study of DTG + TAF + FTC vs DTG + TDF + FTC and EFV + TDF+FTC in First-line Antiretroviral Therapy (ADVANCE)

HIV-1 Infection

South Africa
FHI 360
University of Cape Town; City University of New York, School of Public Health

Completed

Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women

HIV

South Africa
University of Miami
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Promoting Male Involvement to Improve Prevention of Mother to Child Transmission (PMTCT) Uptake and Reduce Antenatal Infection

Pregnancy | HIV

South Africa
University of North Carolina, Chapel Hill
University of Pretoria; SADC Research Centre

Completed

Impact Evaluation of a School-Based Sexuality and HIV Prevention Education Activity in South Africa

HIV Infections | Pregnancy Related | HSV-2 Infection

South Africa
Sanofi Pasteur, a Sanofi Company

Completed

Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Poliomyelitis Vaccine

South Africa
University of Washington
Bill and Melinda Gates Foundation

Completed

Herpes Simplex Virus Type 2 (HSV-2) Suppression to Prevent HIV Transmission

HIV Infection | Sexually Transmitted Diseases | Herpes Simplex, Genital

South Africa, Kenya, Botswana, Rwanda, Tanzania, Uganda, Zambia
International Partnership for Microbicides, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase 3 Safety and Effectiveness Trial of Dapivirine Vaginal Ring for Prevention of HIV-1 in Women (ASPIRE)

HIV Infections

Malawi, South Africa, Uganda, Zimbabwe
University of Miami
National Institute of Mental Health (NIMH); Massachusetts General Hospital; University...

Completed

Effectiveness of Nurse-delivered Care for Adherence/Mood in HIV in South Africa

Depressive Symptoms | Immunodeficiency Virus, Human

South Africa, United States
Columbia University
Centers for Disease Control and Prevention

Completed

Pediatric Enhanced Surveillance Study (PESS)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Cape Town

Completed

Effectiveness & Implementation of a Behavioral Intervention for Adherence and Substance Use in HIV Care in South Africa

Alcohol-Related Disorders | Drug Use | Human Immunodeficiency Virus

United States, South Africa
Johns Hopkins University
Aurum Institute; UNITAID; KNCV Tuberculosis Foundation

Completed

Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial

Tuberculosis Infection | Tuberculosis Prevention

Ethiopia, South Africa
Gilead Sciences

Active, not recruiting

Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected Women

HIV-1-infection

South Africa
International Partnership for Microbicides, Inc.

Completed

A Safety and Tolerability Study of Dapivirine (TMC120) Vaginal Microbicide Gel

HIV Infections

Rwanda, South Africa, Tanzania
Novartis Vaccines

Completed

Magnitude of the Antibody Response to and Safety of a GBS Trivalent Vaccine in HIV Positive and HIV Negative Pregnant Women and Their Offsprings

Bacterial Infections | Streptococcal Infections | Gram-Positive Bacterial Infections

South Africa, Malawi
Cynthia S Firnhaber
Merck Sharp & Dohme LLC

Completed

A Study to Examine the Human Papillomavirus Types Exposure in Women From Southern Africa and Brasil

HIV Infections | HIV

Botswana, Brazil, South Africa
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; University... and other collaborators

Completed

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis (TB TRIAGE+)

Covid-19 | HIV | Pulmonary Tuberculosis | Tuberculosis Diagnosis

Lesotho, South Africa
The Aurum Institute NPC
Johns Hopkins University; University of California

Completed

Safety Tolerability DDI Short Course Treatment of LTBI Infection With High-dose Rifapentine and Isoniazid or Standard Isoniazid Preventive Therapy in HIV+ Patients (DOLPHIN & DOLPHIN TOO) (IMPAACT4TB)

HIV Infections | Respiratory Tract Infections

South Africa
GlaxoSmithKline

Completed

A Study of Safety, Reactogenicity and Immunogenicity of HRV Vaccine in HIV Infected Infants in South Africa

Infections, Rotavirus

South Africa
University of Stellenbosch

Recruiting

Host Blood RNA Signatures for Diagnosis of TB (RADIANT)

Tuberculosis | Lower Respiratory Infection

South Africa
Wake Forest University Health Sciences
National Institute of Mental Health (NIMH)

Not yet recruiting

Adolescents Living With HIV (ALWH): Social Networks, Adherence and Retention

HIV/AIDS

United States, South Africa
AB Science

Recruiting

Masitinib in Patients With Symptomatic Mild to Moderate COVID-19

Covid19 | Coronavirus Disease 2019 | SARS-CoV2 Infection

France, Russian Federation, South Africa
Queen Mary University of London
University of Cape Town

Completed

Trial of Vitamin D Supplementation in Cape Town Primary Schoolchildren (ViDiKids)

Latent Tuberculosis

South Africa
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

Evaluating the Safety and Immunogenicity of HIV-1 Vaccines Based on Chimpanzee Serotypes of Ad Expressing Clade C gp140 and a CH505TF gp120 Protein Boost in Healthy, HIV- Uninfected Adult Participants (HVTN139)

HIV Infections

South Africa
Aeras
Oslo University Hospital; University of Copenhagen; University of Bergen; Aurum... and other collaborators

Withdrawn

A Phase II Study of H56:IC31 in Healthy Adolescents (A-043)

Tuberculosis Infection

South Africa, Tanzania
Emory University
National Institute of Mental Health (NIMH); University of KwaZulu

Completed

InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media (InTSHA)

HIV-1-infection | Adolescent Behavior

South Africa
University of Limpopo

Unknown

Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection

Pneumonia | Bronchiolitis | Acute Lower Respiratory Tract Infection

South Africa

Clinical Trials on BK Virus Infection in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Luxembourg

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Rare Diseases

Drug Interventions

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