Clinical Trials on Brain Injuries, Traumatic in Czechia

Total 521 results

Chiesi Farmaceutici S.p.A.

Active, not recruiting

Open Label Extension of 2 mg/kg Pegunigalsidase Alfa (PRX-102) Every 4 Weeks in Adult Fabry Disease Patients (Bright51)

Fabry Disease

Belgium, United States, United Kingdom, Italy, Czechia, Denmark, Norway
vTv Therapeutics

Completed

Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)

Embolism and Thrombosis | Hip Fractures | Venous Thromboembolism

Denmark, Czech Republic, Norway, Sweden
Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
Chiesi Farmaceutici S.p.A.

Active, not recruiting

Open Label Extension Study of 1 mg/kg Pegunigalsidase Alfa Every 2 Weeks in Patients With Fabry Disease

Fabry Disease

United States, Netherlands, Australia, Hungary, United Kingdom, Canada, Czechia, Finland, France, Italy, Norway, Slovenia, Spain
Czech Technical University in Prague
Mayo Clinic; University Hospital, Montpellier; McGill University Health Centre... and other collaborators

Unknown

Detecting Parkinson's Disease Through Speech Analysis

Parkinson Disease | REM Sleep Behavior Disorder

United States, Canada, Austria, Czechia, France, Germany, Italy
Teva Branded Pharmaceutical Products R&D, Inc.

No longer available

Expanded Access Program for Patients With Migraine

Migraine

Belgium, Canada, Czechia, Italy, Spain, Sweden, United Kingdom
Eisai Inc.

Completed

A Global, Postmarketing Observational Safety Study to Evaluate the Safety and Tolerability of Fycompa (Perampanel) as Add-on Therapy in Epilepsy Patients Aged Greater Than or Equal to 12 Years

Epilepsy

Belgium, Israel, United Kingdom, Austria, Sweden, Czechia
GlaxoSmithKline

Completed

Prophylactic Antipyretic Treatment in Children Receiving Pneumococcal Conjugate and Standard Infant Vaccines

Infections, Rotavirus

Czech Republic
Duke University
Christian Doppler University Hospital

Enrolling by invitation

5-SENSE Score Validation Study

Epilepsy Intractable

United States, Spain, Australia, Austria, Canada, Czechia, Denmark, France, Germany, Japan, Romania, Switzerland
University Hospital Heidelberg
Charles University, Czech Republic; Karolinska University Hospital; Hospices... and other collaborators

Terminated

Efficacy and Safety of Thrombectomy in Stroke With Extended Lesion and Extended Time Window (Tension)

Stroke, Acute | Cerebral Stroke | Cerebrovascular Stroke | Apoplexy; Brain

Germany, Norway, Denmark, Austria, Canada, France, Spain, Switzerland, Czechia, Slovakia
Baxter Healthcare Corporation

Completed

Efficacy and Safety of FS VH S/D 500 S-apr (Tisseel) as an Adjunct to Sutured Dural Repair in Cranial Surgery

Cerebrospinal Fluid Leak

United States, Germany, Spain, Czechia
Rigshospitalet, Denmark
Odense University Hospital; Karolinska University Hospital; Turku University... and other collaborators

Recruiting

Cerebellar Mutism Syndrome Study

Infratentorial Neoplasms | Mutism

Norway, Italy, Netherlands, Denmark, Sweden, Belgium, Finland, Austria, Lithuania, Hungary, United Kingdom, Czechia, Germany
INRESA Pharma
RCTs

Completed

The Sorbact® Antimicrobial Dressing in the Holistic Wound Management Of Diabetic Foot ulCers (Phase III Study) (ADHOC)

Foot Ulcer, Diabetic

France, Czechia, Poland
Radius Health, Inc.

Completed

Twenty-Four Month Extension Study of BA058-05-003 (Abaloparatide) in Participants With Osteoporosis (ACTIVExtend)

Postmenopausal Osteoporosis

Poland, Hong Kong, Romania, Estonia, United States, Argentina, Brazil, Denmark, Lithuania, Czechia
UCB Pharma

Completed

Open-label, Pharmacokinetic, Safety and Efficacy Study of Adjunctive Brivaracetam in Children With Epilepsy.

Epilepsy

Spain, United States, Belgium, Czechia, Mexico, Poland
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Secukinumab in Psoriatic Arthritis and Axial Spondyloarthritis Patients With Active Enthesitis Including One Achilles Tendon Site (ACHILLES)

Psoriatic Arthritis | Enthesitis | Axial Spondyloarthritis

Germany, Spain, United Kingdom, Greece, Bulgaria, Italy, Czechia, Slovakia
Sanofi

Completed

Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Hip Fracture Surgery (SAVE-HIP2)

Venous Thromboembolism

United States, Canada, Poland, Romania, Russian Federation, Ukraine, Italy, Portugal, Spain, Sweden, Turkey, Bulgaria, India, Czech Republic, Mexico, Argentina, Denmark, Finland, Peru, Chile, Belarus, China, South Africa, Greece, Colombia
University Hospital, Lille
European Commission; ApoPharma

Completed

Conservative Iron Chelation as a Disease-modifying Strategy in Parkinson's Disease (FAIRPARKII)

Parkinson Disease

Netherlands, Spain, France, Portugal, Czechia, United Kingdom, Austria, Germany
Universitätsklinikum Hamburg-Eppendorf
Deutsche Kinderkrebsstiftung

Active, not recruiting

International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

Brain Tumors

Germany, Denmark, United Kingdom, Belgium, Poland, Ireland, Austria, Italy, Czechia, France, Netherlands, Norway, Portugal, Spain, Sweden, Switzerland
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery

Muscle Wasting (Atrophy) After Hip Fracture Surgery

Colombia, Belgium, Hungary, Taiwan, Spain, Czechia, United States, France, Germany, Turkey, Japan, Russian Federation, United Kingdom, Argentina, Australia, Mexico, Chile, Switzerland, Austria
Sanofi

Completed

PREVAIL: PREvention of VTE After Acute Ischemic Stroke With LMWH Enoxaparin ( - VTE: Venous Thromboembolism - LMWH: Low Molecular Weight Heparin)

Acute Ischemic Stroke

Korea, Republic of, Italy, Brazil, Canada, Colombia, Israel, Mexico, Poland, Czech Republic, United States, Australia, Austria, India, South Africa, Turkey
Ipsen

Completed

Lanreotide as Primary Treatment for Acromegalic Patients With Pituitary Gland Macroadenoma (PRIMARYS)

Acromegaly

Netherlands, Germany, France, United Kingdom, Turkey, Belgium, Czechia, Finland, Italy
Novartis
Novartis Vaccines

Completed

A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults

Japanese Encephalitis | Rabies | Yellow Fever | Meningococcal Disease | Typhoid | Meningococcal Meningitis

Czech Republic, Germany
European Friedreich's Ataxia Consortium for Translational...

Recruiting

Patient Registry of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) (EFACTS)

Friedreich's Ataxia

Austria, Germany, Italy, Spain, Belgium, Czechia, France, Greece, Ireland, United Kingdom
Elisabethinen Hospital
Baxter Healthcare Corporation; ASOKLIF

Unknown

Evaluation of Immunogenicity of Different Tick Borne Encephalitis (TBE) Fast Protective Traveler Schemes With Inactivated TBE Whole Virus Vaccine (immunisation)

Tick Borne Encephalitis

Austria, Czech Republic
Sanofi

Completed

A Prospective and Retrospective Cohort Study in Patients With Chronic Forms of Acid Sphingomyelinase Deficiency (ASMD)

Sphingomyelin Lipidosis

Italy, Czechia, Belgium, France, Portugal, Turkey, United States, Argentina, Brazil, Chile, Germany, Romania, Spain
Swedish Orphan Biovitrum

Completed

Long Term Safety Study of Orfadin Treatment in HT-1 Patients in Standard Clinical Care (OPAL)

Hereditary Tyrosinemia, Type I

Belgium, Denmark, France, Germany, Austria, Czechia, Finland, Hungary, Ireland, Italy, Netherlands, Norway, Poland, Portugal, Spain, Sweden, United Kingdom
Eli Lilly and Company

Completed

VERtebral Fracture Treatment Comparisons in Osteoporotic Women (VERO)

Postmenopausal Osteoporosis

United States, Germany, Hungary, Italy, Spain, Belgium, France, Poland, Austria, Canada, Puerto Rico, Argentina, Greece, Brazil, Czechia
Genzyme, a Sanofi Company

Active, not recruiting

A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2 (AMETHIST)

Tay-Sachs Disease | Sandhoff Disease

United States, Argentina, Czechia, Portugal, Russian Federation, Turkey, United Kingdom, Brazil, France, Germany, Italy, Japan, Spain
Neurocrine Biosciences

Completed

A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Belgium, Czechia, France, Italy, Australia, Hungary, United Kingdom
Eisai Inc.

Completed

A Study With an Open-label Extension Phase to Evaluate the Effect of Perampanel (E2007) on Cognition, Growth, Safety, Tolerability, and Pharmacokinetics in Adolescents

Epilepsy

United States, Poland, Belgium, India, Korea, Republic of, Thailand, Hungary, Latvia, Czechia, Australia, Spain
Denali Therapeutics Inc.
Takeda

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

Frontotemporal Dementia

Spain, Turkey, France, Belgium, Netherlands, Portugal, Italy, Colombia, Czechia, Brazil, United Kingdom, Serbia
Sygnis Bioscience GmbH & Co KG

Completed

AXIS 2: AX200 for the Treatment of Ischemic Stroke (AXIS-2)

Acute Ischemic Stroke

Spain, Belgium, Germany, Slovakia, Austria, Czech Republic, Poland
Ipsen

Completed

Dysport® Adult Upper Limb Spasticity Extension Study

Nervous System Disorders

United States, France, Belgium, Hungary, Poland, Italy, Czechia, Russian Federation, Slovakia
Daiichi Sankyo, Inc.

Completed

Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke (ASSENT)

Acute Ischemic Stroke | Thrombotic Disease

United States, Korea, Republic of, Taiwan, Australia, Spain, France, United Kingdom, Germany, Czechia, Italy, Slovakia
H. Lundbeck A/S

Completed

A Study With Lu AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments

Migraine

United States, Czechia, Denmark, Georgia, Poland, Slovakia
Technische Universität Dresden

Completed

Psychiatric Day Hospital Treatment

Personality Disorders | Schizophrenia | Anxiety Disorders | Adjustment Disorders | Depressive Disorders

Czech Republic, Germany, Poland, Slovakia, United Kingdom
Daiichi Sankyo, Inc.

Completed

Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acute Spinal Cord Injury (ASCI)

Acute Spinal Cord Injury

France, Spain, United States, Canada, Czechia, Poland, United Kingdom
Bial - Portela C S.A.

Completed

Safety and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy for Partial Seizures in Elderly Patients

Epilepsy

Spain, Bulgaria, Austria, Croatia, Czechia, France, Germany, Poland, Portugal, Romania
Ipsen

Completed

Lanreotide Autogel and Pegvisomant Combination Therapy in Acromegalic Patients

Acromegaly

Germany, Netherlands, Sweden, Czechia, Denmark, France, Greece, Italy, Spain, United Kingdom
Novartis Pharmaceuticals

Completed

A Study Evaluating the Effectiveness of AMG 334 Injection in Preventing Migraines in Adults Having Failed Other Therapies

Episodic Migraine

Austria, Belgium, Italy, Spain, Germany, Sweden, Czechia, Netherlands, France, Denmark, Switzerland, United Kingdom, Greece, Finland, Australia, Norway
Ipsen

Completed

Dysport® Adult Upper Limb Spasticity

Nervous System Disorders

United States, France, Belgium, Poland, Slovakia, Italy, Hungary, Czechia, Russian Federation
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Safety, Tolerability and Efficacy of Weekly TV-1106 in Adults With Growth Hormone Deficiency

Growth Hormone Deficiency

United States, Czechia, Germany, Greece, Hungary, Israel, Serbia, Slovakia, Slovenia
Ever Neuro Pharma GmbH
JSW-Research Forschungslabor GmbH, Parkring 12, 8074 Grambach

Completed

Combined Treatment With Alteplase (Rt-PA) and Cerebrolysin® in Acute Ischemic Hemispheric Stroke (CERE-LYSE-1)

Stroke

Austria, Croatia, Czech Republic, Slovakia, Slovenia
Ipsen

Completed

A Study to Evaluate the Risk of Developing a Heart Condition Called Valvular Regurgitation in Patients With Acromegaly Treated With Either Lanreotide or Octreotide

Acromegaly

Spain, United Kingdom, Italy, France, Belgium, Hungary, Czechia, Denmark, Poland, Sweden
Genzyme, a Sanofi Company

Completed

A Study of Two Fabrazyme (Agalsidase Beta) Dosing Regimens in Treatment-naïve, Male Pediatric Patients Without Severe Symptoms (FIELD)

Fabry Disease

United States, Poland, Netherlands, Canada, Argentina, United Kingdom, Norway, Brazil, Czech Republic
Samson NeuroSciences

Unknown

Safety Study of Carotid Body Neurostimulation to Treat Cerebral Vasospasm

Aneurysmal Subarachnoid Hemorrhage | Cerebral Vasospasm

Germany, Czech Republic, Israel
Pfizer

Terminated

Study Evaluating The Safety And Efficacy Of PF-03049423 In Subjects With Ischemic Stroke

Ischemic Stroke

United States, Taiwan, Korea, Republic of, India, Germany, Canada, France, Bulgaria, Czech Republic, Hungary
Technische Universität Dresden

Unknown

Reversal of the Neurological Deficit in Acute Stroke With the Signal of Efficacy Trial of Auto BPAP to Limit Damage From Suspected Sleep Apnea (Reverse-STEAL)

Ischemic Stroke

United States, Austria, Czech Republic, Germany
Kuros Biosurgery AG
Baxter BioScience

Completed

Adjunctive Therapy to Treat Tibial Shaft Fractures (TSF)

Trauma

Bulgaria, Czech Republic, Finland, France, Germany, Hungary, Italy, Romania, Serbia, Slovakia, Slovenia, Switzerland

Clinical Trials on Brain Injuries, Traumatic in Czechia

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