Clinical Trials on Cardiac Amyloidosis

Total 8822 results

IRCCS Policlinico S. Matteo

Completed

Nutritional Counseling in Systemic Immunoglobulin Light-chain Amyloidosis

Amyloidosis

Italy
CENTOGENE GmbH Rostock
Alnylam Pharmaceuticals

Recruiting

TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects (TRAMmoniTTR)

Cardiomyopathies | Polyneuropathies | Transthyretin Amyloidosis | Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy

Germany, Austria, Switzerland
IRCCS Policlinico S. Matteo

Recruiting

Promoting Diagnosis and Management of AL in Italy (ProDigALIty) (ProDigALIty)

AL Amyloidosis | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

Italy
University of Edinburgh

Unknown

Positron Emission Tomography / Magnetic Resonance Imaging in Aortic Stenosis (PASS)

Aortic Stenosis | Transthyretin Amyloidosis

United Kingdom
RwHealth
Northern Care Alliance NHS Foundation Trust; Alnylam Pharmaceuticals

Not yet recruiting

RWE-based Treatment Patterns and Outcomes in CIDP

Hereditary Amyloidosis | Guillain-Barre Syndrome | Chronic Inflammatory Demyelinating Polyneuropathy

United Kingdom
Universidade do Porto
Centro Hospitalar Universitário São João, E.P.E. (CHUSJ); Centro de Investigação... and other collaborators

Recruiting

Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese Population (CarPoS)

Carpal Tunnel Syndrome | Transthyretin Amyloidosis

Portugal
French Cardiology Society
Pfizer; Henri Mondor University Hospital

Active, not recruiting

Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement. (AMYLOCARTESIAN)

Aortic Valve Stenosis | Amyloidosis | Aging | Heart Disease

France
Brigham and Women's Hospital
GlaxoSmithKline; Ionis Pharmaceuticals, Inc.

Withdrawn

The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart

Amyloidosis
Steen Hvitfeldt Poulsen

Completed

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis (CACTuS - TMZ)

Transthyretin Amyloid Cardiopathy | Mitochondrial Pathology

Denmark
Memorial Sloan Kettering Cancer Center
Millennium Pharmaceuticals, Inc.

Completed

Bortezomib/Dexamethasone (BD), Followed By Autologous Stem Cell Transplantation and Maintenance Bortezomib/Dexamethasone For the Initial Treatment of Monoclonal Immunoglobulin Deposition Disease (MIDD) Associated With Multiple Myeloma and AL Amyloidosis

Amyloidosis | Light Chain Deposition Disease (LCDD or MIDD) | Light Chain and Heavy Chain Deposition Disease (LHCDD or MIDD) | Monoclonal Immunoglobulin Deposition Disease (MIDD)

United States
University Hospital, Bordeaux
University of Bordeaux

Completed

Early and Systematic Screening in Chronic Neuropathy (TTR-FAP)

Amyloid Neuropathies, Familial

France
Universitair Ziekenhuis Brussel

Recruiting

Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause.

Amyloidosis | Polyneuropathy

Belgium
Ostfold University College

Not yet recruiting

Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital

Cardiac Arrest | Cardiac Arrhythmia | Cardiac Disease | Cardiac Death
Jordan Collaborating Cardiology Group

Not yet recruiting

Prevalence of ATTR Cardiac Amyloidosis in Patients Undergoing TAVR

Aortic Valve Stenosis | Severe Aortic Stenosis | ATTR Amyloidosis Wild Type | Middle East Studies
Fundación Pública Andaluza para la gestión de la...

Recruiting

Registry of Patients With Suspected Amyloidosis in Heart Failure (Regamic)

Heart Failure

Spain
Fundación Pública Andaluza para la gestión de la...

Unknown

Prevalence of Amyloidosis in Heart Failure (PREVAMIC) (PREVAMIC)

Heart Failure

Spain
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Insel Gruppe AG, University Hospital Bern
Luzerner Kantonsspital; Cantonal Hospital of St. Gallen; Triemli Hospital

Recruiting

Swiss Cardiac Amyloidosis REgistry (Swiss-CARE) (B-CARE)

Amyloid Cardiomyopathy

Switzerland
Philippe Meyer

Recruiting

Effect of Radiotherapy on ATTR Cardiac Amyloidosis : a Proof of Concept Study

Amyloid Cardiomyopathy

Switzerland
Massachusetts General Hospital

Completed

Characteristics of Patients With Amyloidosis & Heart Failure Being Evaluated for a Heart Transplant

Cardiomyopathy
Groupe Hospitalier Paris Saint Joseph

Withdrawn

Evaluation of New Items in Cardiac Echography (EPIC)

Cardiac Ultrasound | Cardiac Echography
Washington University School of Medicine
Karyopharm Therapeutics Inc

Recruiting

Selinexor and Lenalidomide for Consolidation and Maintenance Treatment in Multiple Myeloma Post-transplant

Multiple Myeloma | Myeloma-Associated Amyloidosis

United States
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Natural History of Severe Allergic Inflammation and Reactions

PGM3 Deficiency | Eosinophilic and/or Atopic Dermatitis | OSMR Deficiency | Primary Localized Cutaneous Amyloidosis | Hereditary Alpha-tryptasemia

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis

Amyloidosis | Plasma Cell Myeloma

United States
Pfizer

Completed

Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis

Familial Amyloid Polyneuropathy

United Kingdom, Spain, United States, Argentina, Brazil, France, Germany, Portugal, Sweden
Shanghai Zhongshan Hospital

Recruiting

The Consistency of Cardiac Output Measured by Pulmonary Artery Catheter and LiDCO in Cardiac Surgical Patients

Cardiac Surgery | Cardiac Output

China
Massachusetts General Hospital

Withdrawn

The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation

Cardiac Physiology | Cardiac Output

United States
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Unknown

Study of Systemic Amyloidosis Presentation and Prognosis

Amyloidosis

United States
Ramsay Générale de Santé
European Clinical Trial Experts Network

Recruiting

Feasibility, Safety and Diagnostic Input of Interventional Cardiac MRI on a Series of 35 Patients With an Indication of Right Cardiac Catheterization. (IRM Cardiaque)

Cardiac MRI | Right Cardiac Catheterization

France
Alnylam Pharmaceuticals

Completed

The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Participants Who Have Already Been Treated With ALN-TTR02 (Patisiran)

Amyloidosis

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Netherlands, Portugal, Spain, Sweden, Taiwan, United Kingdom, Germany, France, Korea, Republic of, Brazil, Mexico, Turkey
Brigham and Women's Hospital

Unknown

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

Amyloidosis

United States
Medtronic Cardiac Rhythm and Heart Failure

Terminated

Optimize RV Selective Site Pacing Clinical Trial

Cardiac Pacemaker, Artificial | Cardiac Pacing, Artificial

Canada, United States, Israel, Italy, Qatar, China
University Hospital, Toulouse

Terminated

Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release Surgery (PRATHYC)

Carpal Tunnel Syndrome | Transthyretin Amyloidosis

France
Pfizer

Completed

An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy | ATTR-PN

Sweden, Brazil, Germany, Argentina, France, Portugal
Centre Hospitalier Régional d'Orléans

Recruiting

Amyloidosis TTR Flow Reserve Evaluation (AMYTRE)

Amyloid Cardiomyopathy

France
Mathew S. Maurer
National Heart, Lung, and Blood Institute (NHLBI); Yale University; Boston Medical... and other collaborators

Recruiting

Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations (SCAN-MP)

Amyloid Cardiomyopathy, Transthyretin-Related

United States
Pfizer

Active, not recruiting

A Study to Learn About the Study Medicine Called Tafamidis 61mg in People Diagnosed With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Transthyretin Amyloid Cardiomyopathy

Korea, Republic of
Pfizer

Completed

A Study to Assess the Safety and Efficacy Of Tafamidis In Chinese Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Transthyretin Amyloid Cardiomyopathy

China
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Getinge...

Completed

Early Initiation of Extracorporeal Life Support in Refractory OHCA (INCEPTION)

Cardiac Arrest | Sudden Cardiac Death | Out-Of-Hospital Cardiac Arrest

Netherlands
Ionis Pharmaceuticals, Inc.

Completed

Extension Study Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP)

Amyloidosis | Familial Amyloid Polyneuropathy | FAP | TTR | Transthyretin

United States, Spain, Argentina, Brazil, France, Germany, Italy, Portugal, United Kingdom
Ionis Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Amyloidosis | Familial Amyloid Polyneuropathy | FAP | TTR | Transthyretin

New Zealand, United States, Spain, Argentina, Brazil, France, Germany, Italy, Portugal, United Kingdom
Jin Lu, MD

Recruiting

Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients With MIDD

Monoclonal Gammopathy of Renal Significance

China
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of Acoramidis (AG10) in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Idoven 1903 S.L.
Spanish Society of Cardiology; Fundación de Investigación en Red en Enfermedades...

Recruiting

AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM) (WILLEM)

Cardiomyopathies | Cardiac Arrest | Sudden Cardiac Death | Cardiac Arrhythmias

Spain
Zoll Medical Corporation

Completed

LifeVest Safety and Efficacy in Real Life Settings in France (WEARIT France)

Sudden Cardiac Death | Cardiac Event | Cardiac Arrythmias | Left Ventricular Dysfunction

France
Johns Hopkins University

Terminated

EPOgen and Restrictive Transfusions in Patients Undergoing Cardiac Surgery (EPORT) (EPORT)

Cardiac Valve Replacement | Cardiac Surgery-CABG

United States
Charite University, Berlin, Germany

Unknown

Effects of Endurance Training on Patients With Reduced Left Ventricular Ejection Fraction (LVEF) and Cardiac Resynchronisation Therapy Especially for Cardiac Arrhythmias

Heart Failure | Sudden Cardiac Death | Cardiac Resynchronisation Therapy

Germany
Medical College of Wisconsin

Unknown

Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).

Heart Arrest | Cardiac Arrest | Sudden Cardiac Death | Cardiopulmonary Arrest | Out of Hospital Cardiac Arrest

United States
Barbara Ann Karmanos Cancer Institute

Completed

COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies

Multiple Myeloma | AL Amyloidosis | Chronic Lymphocytic Leukemia

United States
University Hospital, Bordeaux

Completed

Neuropathy in Patients Monitored for Wild-type TTR Cardiac Amyloidosis (Non-mutated) (N-SAC)

Wild-type Amyloid Cardiopathy

France

Clinical Trials on Cardiac Amyloidosis

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