Clinical Trials on Chronic HIV-1 Infection

Total 14219 results

University of Oxford

Completed

Safety and Immunogenicity Study of Three Candidate HIV-1 Vaccines, Administered in Combination to Healthy HIV-1 Uninfected Adults (HIV-CORE 002)

HIV-1 Infections

United Kingdom
Shanghai Public Health Clinical Center

Completed

Zadaxin and HIV-positive Patients With Immune Reconstitution Disorder

HIV-1-infection

China
Luis Montaner
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Unknown

Peg-Interferon Alpha 2b Combined With Two Intravenous Broadly HIV-1 Neutralizing Antibodies 3BNC117 and 10-1074 (BEAT-2) (BEAT-2)

HIV/AIDS | HIV | HIV-1 Infection

United States
Medical University of Warsaw

Not yet recruiting

HIV Drug Resistance Pattern Due to Migration in Poland

HIV Infections | HIV-1-infection | Resistant Infection

Poland
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy

Pregnancy | HIV-1-infection | Postpartum

United States, South Africa
Emory University
National Institute of Mental Health (NIMH); University of KwaZulu

Completed

InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media (InTSHA)

HIV-1-infection | Adolescent Behavior

South Africa
ANRS, Emerging Infectious Diseases
ViiV Healthcare

Completed

Cartography of Virologic Reservoir Related to Antiretroviral Concentrations in HIV-1 Chronic Patients Treated by a First Line Treatment Containing Dolutegravir and Associated Nucleoside / Nucleotide Reverse Transcriptase Inhibitors Backbone (DOLUVOIR)

HIV-1 Infection

France
Montefiore Medical Center
National Institute on Drug Abuse (NIDA); University of Michigan; George Washington...

Completed

A Mobile Intervention to Promote Cessation in HIV-infected Smokers

Tobacco Use | HIV-1-infection

United States
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Doravirine (MK-1439) (MK-1439-019)

HIV-1 Infection
RetroLead (Shanghai) BioPharma Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral HRS5685 in Healthy Subjects

Human Immunodeficiency Virus-1 (HIV-1) Infection
National Institute of Allergy and Infectious Diseases...
Gilead Sciences; University of Oxford

Recruiting

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

HIV-1-infection

United States, Brazil
ANRS, Emerging Infectious Diseases
INSERM SC10-US19

Recruiting

Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load (SYNACTHIV)

HIV-1-infection, Subtype b

Belgium, France
University of Washington

Completed

Social Media for ART Adherence and Retention in Adolescents and Young Adults: the Vijana-SMART Study

Depression | Adherence, Medication | HIV-1-infection

Kenya
National Institutes of Health Clinical Center (CC)

Completed

Community-based Treatment of Chronic Hepatitis C Monoinfection and Coinfection With HIV in the District of Columbia

HCV HIV

United States
Erasmus Medical Center

Recruiting

Self-testing for HCV Re-infection in MSM (SELFIE)

HIV-1-infection | Hepatitis C Recurrent

Netherlands
University of Liverpool
Radboud University Medical Center; University of Cape Town; UNITAID; Liverpool... and other collaborators

Completed

Dolutegravir in Pregnant HIV Mothers and Their Neonates (DolPHIN-2)

Pregnancy Related | HIV-1-infection

Uganda, South Africa
Johns Hopkins University

Completed

Nurse Case Management to Improve Hepatitis C Care in HIV Co-infection (Care2Cure)

Hepatitis C, Chronic | HIV

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C203: Phase II Randomized (Patients Are Assigned Different Treatments Based on Chance), Placebo Controlled Dose Escalating Trial of TMC125 in HIV-1 Infected Patients

HIV-1 | Anti-Retroviral Agents
AbbVie

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1

HIV Infection | HIV-1 | Human Immunodeficiency Virus (HIV)

United States, Australia, Canada, Puerto Rico
Federal University of São Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de... and other collaborators

Completed

Multi Interventional Study Exploring HIV-1 Residual Replication: a Step Towards HIV-1 Eradication and Sterilizing Cure

HIV | Chronic Infection

Brazil
University College, London
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Active, not recruiting

Long-Acting Treatment in Adolescents (LATA) (LATA)

HIV Infections | Hiv | HIV-1-infection | Paediatric Human Immunodeficiency Virus Infection

Uganda, Zimbabwe, Kenya, South Africa
National Taiwan University Hospital

Unknown

NUC in Preventing HBV Reactivation in HCV/HBV Co-infected Patients Receiving DAA for CHC

HBV/HCV Co-infection

Taiwan
Université de Sherbrooke

Completed

Epidemic History and Iatrogenic Transmission of Blood-borne Viruses in Mid-20th Century Kinshasa

Hepatitis C, Chronic | HIV | HTLV-1
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study to Evaluate Effects of Vorinostat and HXTC on Persistent HIV-1 Infection in HIV-Infected Subjects Started on Antiretroviral Therapy (ART) (XTRA)

HIV-1 Infection

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Pilot Trial of the Effect of Vorinostat and AGS-004 on Persistent HIV-1 Infection (VORVAX)

HIV-1 Infection

United States
Inovio Pharmaceuticals

Completed

Study of PENNVAX™-B (Gag, Pol, Env) + Electroporation in HIV-1 Infected Adult Participants (HIV-001)

HIV Infections | HIV-1 Infection

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Open-label, Follow-up of Doravirine/Islatravir (DOR/ISL 100 mg/0.75mg) for Participants With Human Immunodeficiency Virus-1 (HIV-1) Infection (MK-8591A-033)

HIV-1 Infection

United States, Australia, Canada, Chile, Colombia, France, Germany, Italy, Japan, New Zealand, Poland, Russian Federation, South Africa, Spain, Switzerland, United Kingdom
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Recruiting

Group-Based Intervention to Improve Mental Health and Adherence Among Youth Living With HIV in Low Resource Settings

HIV-1-infection

Zimbabwe, Botswana, Malawi, South Africa
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; Centre Muraz

Active, not recruiting

Preventing Childhood HIV: Rescue Intervention. ANRS 12388 PREVENIR-PEV (PREVENIR-PEV)

HIV-1

Burkina Faso
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Phase 1, Open-label, Single Dose Study to Examine Safety, Tolerability, Pharmacokinetics and Virologic Impact of VRC01LS or VRC07-523LS in HIV-infected Viremic Adults

HIV-1

United States, Puerto Rico
Janssen-Cilag Pty Ltd

Completed

Long Term Follow-Up Study of Human Immunodeficiency Virus Type 1 (HIV-1) Positive Patients Who Have Received OZ1 Gene Therapy as Part of a Clinical Trial

HIV-1

United States, Australia
Pfizer

Completed

A Study Of Different Doses Of UK-453, 061 Plus Truvada Compared To Efavirenz Plus Truvada In Patients Who Have Not Been Previously Treated For HIV-1

HIV-1

United Kingdom, South Africa, Australia, Canada, Italy, Poland, Switzerland, Argentina, Mexico
Oslo University Hospital
Karolinska University Hospital; Tine

Completed

The Effect of Probiotics in HIV-1 Infection (ProGut)

HIV-1 Infection

Norway, Sweden
Castagna Antonella
ViiV Healthcare

Recruiting

Italian Registry of HIV-1 Infected Patients With Drug-RESistant Virus to Reverse Transcriptase Inhibitors, InteGrasE and Viral Protease. (PRESTIGIO)

HIV-1-infection | Multi-Antiviral Resistance

Italy
United BioPharma

Not yet recruiting

UB-421 in Combination With Optimized Background Regimen in Patients With Multi-drug Resistant HIV-1 Infection

HIV-1 Infection
United BioPharma

Not yet recruiting

UB-421 Combine With Optimized Background Therapy Regimen in Multi-Drug Resistant HIV-1 Infection Patients

HIV-1 Infection
Canadian Immunodeficiency Research Collaborative
Hoffmann-La Roche

Completed

Fuzeon Viral Decay Pilot Study

HIV-1

Canada
University Hospital, Rouen
Hoffmann-La Roche

Terminated

Prospective Evaluation Among Patients Infected by HIV 1 in Virological Failure Owing to Lack of Compliance, of the Benefit in Terms of Compliance of an Optimised Antiretroviral Treatment With Enfuvirtide (Fuzeon) Associated With Two Active Molecules (AMPHORE)

HIV Infections | HIV1 Infection

France
Taoyuan General Hospital
Merck Sharp & Dohme LLC

Completed

Efficacy and Tolerability of Grazoprevir and Elbasvir in Patients With Chronic Genotype 1 HCV and HIV Co-infection

Chronic Hepatitis C

Taiwan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Viral Infection of HSPC Impacts Hematopoiesis (MEGAHOST)

SARS-CoV-2 | HIV-1

France
Makerere University
Infectious Diseases Institute, Uganda

Completed

Call for Life Youth ART Adherence Study (C4L-Youth)

mHealth | HIV-1-infection | ART Adherence

Uganda
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC

Completed

Prevalence, Characteristics and Risk Factors of HIV-Associated Neurocognitive Disorders in Subjects Between the Ages of 55 and 70 Years: An Exposed/Unexposed Cross Sectional Study (HAND55-70)

HIV-1 Infection

France
Juan Macías

Completed

Changes in Liver Steatosis After Switching to Raltegravir in HIV/HCV Coinfection (STERAL)

HIV Infection | HCV Coinfection

Spain
Pedro Cahn
Merck Sharp & Dohme LLC

Unknown

RAL+ATV/r in Comparison With TDF/FTC (or 3TC) +ATV/r in HIV Infected Patients (ARTE)

Chronic Infection With HIV

Argentina
U.S. Army Medical Research and Development Command
Walter Reed Army Institute of Research (WRAIR); Mahidol University; Sanofi Pasteur... and other collaborators

Completed

Follow up of Thai Adult Volunteers With Breakthrough HIV Infection After Participation in a Preventive HIV Vaccine Trial

HIV-1

Thailand
Pfizer
ViiV Healthcare

Terminated

A Rollover Study For Subjects Discontinuing From UK-453,061 Studies For The Treatment Of HIV-1

HIV-1

United States, United Kingdom, Portugal, Ukraine, Italy, Poland, Switzerland, Argentina, South Africa, Puerto Rico, Brazil, Malaysia
ViiV Healthcare
Pfizer

Completed

Non-Interventional Study Of Celsentri® In Treatment Experienced Patients With CCR5-Tropic HIV-Infection

HIV-1
Tibotec Pharmaceuticals, Ireland

Terminated

TMC278-TiDP15-C150: Trial to Examine Safety, Tolerability and Plasma Pharmacokinetics of Multiple Doses of TMC278LA.

HIV-1
Tibotec Pharmaceuticals, Ireland

Completed

PEPI-TiDP23-C103: First-in-Human Study to Examine the Safety, Tolerability, and Plasma Pharmacokinetics of Increasing Single and Repeated Oral Doses of TMC558445 and of a Combined Single Day Dosing of Oral TMC558445 and Oral TMC310911 and Also Oral Darunavir

HIV-1
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Sofosbuvir-Containing Regimens Without Interferon For Treatment of Acute Hepatitis C Virus (HCV) Infection (SWIFT-C)

Hepatitis | HIV-1 Infection

United States

Clinical Trials on Chronic HIV-1 Infection

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CROs in Vietnam

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Rare Diseases

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