Clinical Trials on Chronic Total Occlusion (CTO)

Total 788 results

Heart Care Foundation

Completed

STable Coronary Artery Diseases RegisTry (START)

Chronic Ischemic Heart Disease

Italy
OPKO Health, Inc.

Active, not recruiting

Safety, Efficacy, PK and PD of CTAP101 (Calcifediol) ER Capsules for SHPT in HD Patients VDI

Chronic Kidney Diseases | Vitamin D Deficiency | Stage 5 Chronic Kidney Disease | Secondary Hyperparathyroidism Due to Renal Causes

United States
University of Leeds
Edinburgh Molecular Imaging Ltd

Completed

EMI-137 in Laparoscopic Colonic Resections

Colonic Cancer | Metastasis to Lymph Node

United Kingdom
University of Calgary

Completed

ENCOMPASS: Expansion Study B, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Glasgow Caledonian University
University of Nottingham; University of Manchester; University of Strathclyde; Edinburgh... and other collaborators

Completed

Helping Ease Anxiety and Depression Following Stroke Stage 3 (HEADS:UP)

Depression | Stroke | Anxiety | Cerebrovascular Accident Due to Cerebral Artery Occlusion

United Kingdom
The University of The West Indies

Completed

The Effects of loW Dose tIcagrelor on Platelet Function Testing in Patients With Stable Coronary arTery Disease (TWIST)

Platelet Dysfunction Due to Drugs

Trinidad and Tobago
Cardio Med Medical Center
George Emil Palade University of Medicine, Pharmacy, Sciences and Technology... and other collaborators

Recruiting

CCTA Coronary Hemodynamics, Systemic Inflammation and Vulnerable Plaques (COHESIVE) (COHESIVE)

Coronary Artery Disease | Atherosclerosis | Chronic Coronary Syndrome | Systemic Inflammatory Response

Romania
VIVA Physicians
Prairie Education and Research Cooperative

Completed

Study to Evaluate the Safety & Performance of the Xpert(TM) Stent in Treating Below-the-knee Lesions in Patients Undergoing Percutaneous Intervention for Chronic CLI. (XCELL)

Peripheral Vascular Diseases | Chronic Critical Limb Ischemia

United States
University of British Columbia
University of Sydney

Recruiting

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates (CARSK)

Cardiovascular Diseases | End Stage Renal Disease | Kidney Transplantation | Dialysis Related Complication

Canada, United States, United Kingdom, Germany
CSL Behring

Enrolling by invitation

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

End Stage Kidney Disease | Atherosclerotic Cardiovascular Disease

United States, Australia, Belgium, Canada, Germany
University of Calgary
University of Alberta

Completed

ENCOMPASS: Expansion Study A, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Merck Sharp & Dohme LLC

Completed

Study of Sotatercept for the Treatment of Anemia in low-or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) or Non-proliferative Chronic Myelomonocytic Leukemia (CMML)

Myelodysplastic Syndromes | Anemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndromes (MDS) | Chronic Myelomonocytic Leukemia (CMML) | Low to Intermediate-1 MDS

United States, France
Shanghai Hongyitang Biopharmaceutical Technology...

Completed

A Phase IIa Clinical Trial on TSG-01 in the Treatment of Chronic Heart Failure in Patients With Coronary Heart Disease.

Chronic Heart Failure

China
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Intracoronary Infusion of Bone Marrow Mononuclear Cells in Patients With Previous Myocardial Infarction.

Chronic Myocardial Ischemia

Spain
University of Calgary
University of Alberta

Completed

ENCOMPASS: Expansion Study C

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
University of Calgary
Alberta Innovates Health Solutions; Canadian Diabetes Association

Completed

Enhancing Community Health Through Patient Navigation, Advocacy and Social Support (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Centre Hospitalier Universitaire de Nīmes

Completed

Mobile Unit Screening of Pathologies Associated With Chronic Diseases - Feasibility (DéProPAss)

Chronic Obstructive Pulmonary Disease | Atherosclerosis | Type II Diabetes

France
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); US...

Completed

Biomarker Effectiveness Analysis in Contrast Nephropathy (BEACON)

Kidney Diseases | Chronic Kidney Disease | Acute Renal Failure | Coronary (Artery); Disease
University of Maryland, Baltimore
Merck Sharp & Dohme LLC; Cairo University

Withdrawn

Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4 (CLEAR-C4)

Hepatitis C Virus Infection, Response to Therapy of

Egypt
Indiana University School of Medicine
Dialysis Clinic, Inc.

Completed

T Wave Alternans in Hemodialysis

End Stage Renal Disease | Coronary Heart Disease | Congestive Heart Failure

United States
University Health Network, Toronto

Not yet recruiting

meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis (CANARY)

End Stage Kidney Disease | Kidney Dysfunction | Peritoneal Dialysis Complication | Sodium-glucose Co-transporter-2 Inhibitors | Residual Kidney Function

Canada
Instituto Nacional de Ciencias Medicas y Nutricion...
Olynka Vega Vega; Noemi del Toro Cisneros; Miguel Ángel Martínez Rojas

Recruiting

Dapaglifozin to Avoid Acute Kindey Injury (AKI) to Chronic Kidney Disease (CKD) Transition: DAKI-CKD Study (DAKI-CKD)

Biomarkers | CKD | AKI - Acute Kidney Injury | Transition to CKD

Mexico
University Hospital, Essen

Recruiting

Effect of Acute Cardiovascular Disease on Microbiome (MIAMI)

Myocardial Infarction | Coronary Artery Disease | Peripheral Arterial Disease | Acute Coronary Syndrome | Microbial Colonization | Critical Limb Ischemia

Germany
Denver Health and Hospital Authority

Recruiting

Enhancing Cardiac Rehabilitation Through Behavioral Nudges

Coronary Artery Disease | Percutaneous Coronary Intervention | Acute Myocardial Infarction | Chronic Stable Angina | Chronic Stable Heart Failure | Valvular Disease

United States
Mayo Clinic
University of Alabama at Birmingham; University of Mississippi Medical Center

Completed

Hypoxia and Inflammatory Injury in Human Renovascular Hypertension

Chronic Kidney Disease | Renal Artery Stenosis | Ischemic Nephropathy | Renovascular Disease

United States
Wake Forest University Health Sciences
Astellas Pharma US, Inc.

Terminated

Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR)

Coronary Artery Disease | Asthma | Chronic Obstructive Pulmonary Disease (COPD) | Angina

United States
Far Eastern Memorial Hospital

Unknown

The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients

Atherosclerosis | Anemia | Oxidative Stress | End-Stage Renal Disease | Pro-Inflammation

Taiwan
Aristotle University Of Thessaloniki

Unknown

Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices

End Stage Renal Disease | Hypotension During Dialysis | Protein Malnutrition | Arterial Sclerosis

Greece
Chinese PLA General Hospital
Beijing Normal University

Unknown

Efficacy and Mechanism of TCCRP in Patients With Chronic Coronary Syndrome Under Fusion Cardiac Rehabilitation Model

Coronary Heart Disease | Chronic Coronary Syndrome

China
Marlous Hall

Completed

Association of Long-term Conditions With Survival Following Heart Attack in England and Wales

Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Peripheral Vascular Disease | Chronic Heart Failure | Acute Myocardial Infarction | Chronic Renal Failure | Cerebrovascular Disease
Kawin Technology Share-holding Co., Ltd.
KawinGreen Biotech Co., Ltd.

Completed

Safety and Efficacy of Generic Sofosbuvir and Ribavirin for Treatment-naive Genotype 2 Chronic Hepatitis C (SOF_GT2)

Hepatitis C, Chronic | Hepatitis C Virus Infection, Response to Therapy of

China
Nanfang Hospital of Southern Medical University
Gilead Sciences; Tigermed Consulting Co., Ltd

Recruiting

Preventing Mother-to-child Transmission of Hepatitis B Virus With Tenofovir Alafenamide (TAF)

Hepatitis B, Chronic | Mother to Child Transmission

China
Nanfang Hospital of Southern Medical University
Tigermed Consulting Co., Ltd; Chinese Foundation for Hepatitis Prevention and...

Recruiting

Mother-to-child Transmission of HBV in China

Hepatitis B, Chronic | Mother to Child Transmission

China
Masaryk University

Withdrawn

The Effect of Gabapentin Used as a Preemptive to the Emergence and Development Chronic Neuropathic Pain in Patients After Spinal Cord Trauma (GabaNeuBol)

Spinal Cord Injuries | Chronic Pain Due to Trauma

Czechia
China Medical University Hospital

Unknown

The Correlation Between Genetic Polymorphism, Platelet Activity, Clopidogrel Responsiveness, and Serum Adipokine Concentration in Asian Acute Coronary Syndrome Patients

Acute Coronary Syndrome | Chronic Coronary Artery Disease

Taiwan
Texas Woman's University

Completed

Measuring Head Control Change With 2D Video Analysis After Utilization of Headpod in Children With Poor Head Control (headpod)

Cerebral Palsy | To Determine Efficacy of the Headpod

United States
University of Nebraska
Nevro Corp

Not yet recruiting

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

Diabetes Mellitus, Type 2 | Chronic Pain | Peripheral Arterial Disease | Chronic Pain Syndrome | Painful Diabetic Neuropathy | Limb Pain | Spinal Cord Stimulation

United States
Stempeutics Research Pvt Ltd

Withdrawn

A Clinical Trial to Study the Efficacy and Safety of Stempeucel® in Patients With CLI Due to Buergers Disease

Critical Limb Ischemia Due to Buerger's Disease

India
Adam Kittai

Recruiting

Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome

Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Transformed B-Cell Non-Hodgkin Lymphoma | Refractory Transformed Non-Hodgkin Lymphoma | Refractory Transformed B-cell Non-Hodgkin Lymphoma | Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma | Recurrent Transformed... and other conditions

United States
Assiut University

Recruiting

Clinical Outcomes Following Surgical Debridement of Diabetic Foot Infection With Borderline Vascularity

Chronic Limb Threatening Ischemia

Egypt
Euro CTO Club
NHS Research and Development; Biosensors International; Asahi Intecc Co., Ltd.

Completed

A Randomized Multicentre Trial to Evaluate the Utilization of Revascularization or Optimal Medical Therapy for the Treatment of Chronic Total Coronary Occlusions (EuroCTO)

Coronary Occlusion | Dyspnea | Chronic Stable Angina

United Kingdom, Spain, France, Germany, Italy, Latvia
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

A Study on Prevention Strategies for CKD-SHPT and Related Complications Based on General Vitamin D Supplementation

Vitamin D Deficiency | Chronic Kidney Disease 5D | Secondary Hyperparathyroidism Due to Renal Causes

China
Ain Shams University

Completed

Chamomile Effect on Xerostomia Associated With End-stage Renal Disease in Elderly

Xerostomia Due to Hyposecretion of Salivary Gland

Egypt
University of Southern California
National Institute on Aging (NIA); Huntington Hospital

Completed

Social Work Intervention Focused on Transitions (SWIFT)

Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention

United States
Samsung Medical Center
Medipost Co Ltd.

Unknown

Umbilical Cord Blood-derived Mesenchymal Stem Cells for the Treatment of Steroid-refractory Acute or Chronic Graft-versus-host-disease (GVHD-MSC)

Graft-Versus-Host Disease | GVHD | Disorder Related to Transplantation | Allogeneic Hematopoietic Transplant

Korea, Republic of
Rigshospitalet, Denmark

Not yet recruiting

68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Angiogenesis in Ischemic Heart Disease

Chronic Ischemic Heart Disease

Denmark
Tomsk National Research Medical Center of the Russian...

Completed

Results of Coronary Artery Bypass Grafting in Obese Patients

Obesity | Chronic Ischemic Heart Disease

Russian Federation
University Hospital, Toulouse
Ministry of Health, France; Nantes University Hospital; French Blood Establishment

Completed

Mesenchymal Stem Cells and Myocardial Ischemia (MESAMI)

Left Ventricular Dysfunction | Chronic Myocardial Ischemia

France
Johns Hopkins University

Recruiting

Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients (VA-ECMO)

Compartment Syndrome of Leg | Extracorporeal Membrane Oxygenation Complication | Limb Ischemia, Critical | Limb Ischemia

United States
University of Alberta
Alberta Health services; Alberta Health & Wellness; Merck Frosst Canada Ltd.

Completed

The Alberta Vascular Risk Reduction Community Pharmacy Project: RxEACH (RxEACH)

Diabetes | Chronic Kidney Disease | Established Atherosclerotic Vascular Disease | Framingham Risk Score More Than 20 Percent

Canada

Clinical Trials on Chronic Total Occlusion (CTO)

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