Clinical Trials on Critical Aortic Stenosis in Japan

Total 102 results

Medico's Hirata Inc.

Terminated

Safety and Efficacy of SYM-SV/DS-002 in Patients With Severe Aortic Stenosis

Severe Aortic Stenosis

Japan
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis:CE-approval Cohort

Symptomatic Aortic Stenosis

Germany, Japan, Brazil
Edwards Lifesciences

Active, not recruiting

A Clinical Trial of Transcatheter Aortic Valves in Dialysis Patients (Japan)

Aortic Stenosis

Japan
OCEAN-SHD Study Group

Recruiting

Non-antithrombotic Therapy After Transcatheter Aortic Valve Implantation Trial

Aortic Stenosis | Aspirin | TAVI(Transcatheter Aortic Valve Implantation) | DAPT(Dual Antiplatelet Therapy) | SAPT(Single Antiplatelet Therapy)

Japan
Medtronic Cardiac Surgery
Medtronic

Completed

PERIGON Japan Trial

Aortic Stenosis

Japan
Boston Scientific Corporation

Completed

Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve Replacement (REPRISE Japan)

Aortic Stenosis

Japan
Bristol-Myers Squibb

Recruiting

A Study to Assess Health-Related Quality of Life in Patients With Hypertrophic Cardiomyopathy in Japan

Hypertrophic Cardiomyopathy

Japan
Kumamoto University

Completed

Assessments of Thrombus Formation in TAVI

Aortic Valve Stenosis | Heart Valve Diseases

Japan
Edwards Lifesciences

Completed

PREVAIL-J - Transfemoral & Transapical Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Japan)

Aortic Valve Stenosis

Japan
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Small Aortic Annuli and Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
Nobuyuki Katori
Baxter Healthcare Corporation

Unknown

Desflurane-induced Myocardial Protection

Aortic Valve Stenosis

Japan
Edwards Lifesciences

Completed

PREVAIL-20J - Transfemoral Placement of 20mm Aortic Balloon Expandable Transcatheter Valve Trial (PREVAIL-20J)

Aortic Valve Stenosis

Japan
Osaka University

Completed

Predictors Of Successful Extubation in Critically Ill Patients: Multicentre Observational Study (POSE)

Intubation | Critical Care | Extubation | Mechanical Ventilation | Weaning | Liberation From Mechanical Ventilation

Japan
Cook Group Incorporated

Completed

Zenith Low Profile AAA Endovascular Graft (ZLP) Clinical Study (ZLP)

Abdominal Aortic Aneurysm | Iliac Aneurysm | Aorto-iliac Aneurysm

Japan
Edwards Lifesciences

Recruiting

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR (PROGRESS)

Aortic Valve Stenosis | Aortic Stenosis, Calcific

United States, Switzerland, Australia, Japan, Canada, Netherlands
Edwards Lifesciences

Active, not recruiting

PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis (P3)

Aortic Stenosis

United States, Australia, Japan, Canada, New Zealand
Seung-Jung Park
CardioVascular Research Foundation, Korea

Completed

The Asian Transcatheter Aortic Valve Replacement Registry (Asian TAVR)

Aortic Valve Stenosis | Aortic Diseases

Korea, Republic of, China, Taiwan, Japan, Singapore
Bristol-Myers Squibb

Active, not recruiting

A Study of Mavacamten in Obstructive Hypertrophic Cardiomyopathy (HORIZON-HCM)

Cardiomyopathy, Hypertrophic Obstructive

Japan
Michael Kang-Yin Lee, MD
Asan Medical Center; Cardiovascular Clinical Research

Unknown

The Asian Pacific TAVR Multicenter Registry (AP TAVR)

Aortic Valve Stenosis

Korea, Republic of, Thailand, Malaysia, Taiwan, Japan, China, Philippines, Singapore
Medtronic Cardiovascular

Recruiting

Evolut™ EXPAND TAVR II Pivotal Trial

Moderate Aortic Valve Stenosis

United States, France, Netherlands, Canada, Spain, Israel, Australia, Denmark, Germany, Italy, Japan, Switzerland, Belgium, Sweden, Austria, United Kingdom, Ireland
Mitsui Memorial Hospital
Teikyo University; Tokai University

Unknown

Effect of Combination of Non-sLip Element Balloon (NSE) and druG-coated bAlloon (DCB) for In-steNT Restenosis Lesions (ELEGANT)

Coronary Restenosis

Japan
Bristol-Myers Squibb

Active, not recruiting

A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy (ODYSSEY-HCM)

Cardiomyopathy, Hypertrophic

Spain, Austria, Belgium, Brazil, Canada, Denmark, France, Germany, Hungary, Israel, Japan, Netherlands, Norway, Poland, Portugal, United Kingdom, United States, Australia, China, Czechia, India, Italy, Korea, Republic of
Philip Morris Products S.A.

Completed

Comparison of Abdominal Aortic Aneurysm Growth in Adult Smoking Patients Who Either Switch to IQOS, Continue Smoking, or Quit Smoking.

Smoking | Abdominal Aortic Aneurysm | IQOS Use

Japan
W.L.Gore & Associates

Active, not recruiting

Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta (Zone 0/1) (SSB 11-02)

Aortic Aneurysm, Thoracic | Aorta, Lesion

United States, Japan
C. R. Bard
Medicon, Inc.

Completed

LEVANT Japan Clinical Trial

Femoral Artery Occlusion | Femoral Arterial Stenosis | Stenosis of Popliteal Arteries | Occlusion of Popliteal Arteries

Japan
Medtronic Cardiovascular
NAMSA

Active, not recruiting

DISSECT-N Post Market Data Collection Registry (DISSECT-N)

Thoracic Aortic Dissection

United States, Korea, Republic of, Netherlands, Denmark, New Zealand, Thailand, Japan, Slovakia, Greece, Italy
Cordis Corporation
Quintiles, Inc.; HealthCore-NERI

Completed

A Multicenter, Open Label, Prospective, Non-randomized Study of the InCraft® Stent Graft System in Subjects With Abdominal Aortic Aneurysms (INSPIRATION) (INSPIRATION)

Abdominal Aortic Aneurysm

United States, Japan
Medtronic Endovascular

Completed

MDT-2113 Drug-Eluting Balloon vs. Standard PTA for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery and/or Proximal Popliteal Artery (MDT-2113 SFA)

Popliteal Artery Stenosis | Popliteal Artery Occlusion | Femoral Artery Occlusion | Femoral Artery Stenosis

Japan
Medtronic Cardiovascular

Active, not recruiting

Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients

Aortic Valve Stenosis

United States, Australia, New Zealand, Canada, Netherlands, France, Japan
Bayer

Completed

Bioequivalence Study of BAY 77-1931 Orally Disintegrating Tablet

Clinical Pharmacology

Japan
Imperial College London
McGill University; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Completed

Protocoled Quantitative Assessment of Aortic Regurgitation Using Videodensitometry in a Multicontinental Trial in Rotterdam, Montreal, Yamaguchi, Segeberg, Amsterdam. (ASSESS-REGURGE)

Aortic Valve Insufficiency | Aortic Valve Regurgitation

Netherlands, Canada, Germany, Japan, United Kingdom
Abbott Medical Devices

Completed

XIENCE PRIME Japan Post-Marketing Surveillance (PMS)

Myocardial Ischemia | Coronary Artery Disease | Coronary Occlusion | Coronary Artery Stenosis | Angina

Japan
Abbott Medical Devices

Completed

AVJ-514 Japan Trial

Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency | Functional Mitral Regurgitation | Mitral Stenosis With Insufficiency

Japan
Abbott Medical Devices

Completed

A Clinical Evaluation of the XIENCE PRIME Small Vessel Everolimus Eluting Coronary Stent System in Japanese Population (SV JAPAN)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Coronary Restenosis | Vascular Disease | Coronary Artery Stenosis

Japan
Takeda

Completed

TAK-114 Single- and Multiple-Dose Phase 1 Study

Clinical Pharmacology

Japan
Takeda

Completed

Effect of Food on the Pharmacokinetics of Single Oral Dose Administration of a Fixed-Dose Combination of SYR-322 and Metformin Hydrochloride in Healthy Adult Male Subjects

Clinical Pharmacology

Japan
Takeda

Completed

A Phase I Clinical Pharmacology Study of TAK-233 in Healthy Subjects

Clinical Pharmacology

Japan
Osaka University
Hospital Rebagliati

Unknown

Prone Positioning and Spontaneous Breathing (PROSE)

Critical Illness | ARDS

Japan
Ethicon Endo-Surgery

Completed

A Study of the ENSEAL® X1 Curved Jaw Tissue Sealer and Generator G11 in Thoracic, Urologic, and Ear, Nose, and Throat (ENT) Procedures

Thoracic Procedure | Urologic Procedure | Ear, Nose and Throat Procedure

United Kingdom, Japan, United States, Netherlands
Bayer
Janssen Research & Development, LLC

Completed

Study to Compare the Effect of the Formulations (Orally Disintegrating Tablet and Film-coated Tablet) on Bioequivalence of Drug Rivaroxaban (Xarelto) at Dose of 10 mg in Japanese Healthy Male Adult Subjects

Clinical Pharmacology

Japan
Cook Group Incorporated

Completed

Zenith® TXD Post-market Surveillance in Japan

Aortic Dissection

Japan
Bayer
Janssen Research & Development, LLC

Completed

Study to Compare the Effect of the Formulations (Orally Disintegrating Tablet and Film-coated Tablet) on the Bioequivalence of Drug Rivaroxaban (Xarelto) at Dose of 15 mg in Japanese Healthy Male Adult Subjects

Clinical Pharmacology

Japan
Hyogo College of Medicine

Withdrawn

Relationship Between Pressure and Flow Velocity on Coronary Physiology

Coronary Stenosis

Japan
Kurashiki Central Hospital

Unknown

Bifurcation Stenting Using 2 Link Stent Nobori Versus 3 Link Stent Xience (BEGIN)

Coronary Stenosis

Japan
Abbott Medical Devices

Completed

XIENCE V/PROMUS Everolimus-Eluting Stent System Post-marketing Surveillance Protocol for Japan

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Stent Thrombosis | Coronary Restenosis | Chronic Coronary Occlusion | Vascular Disease | Coronary Artery Stenosis | Angina

Japan
Deep Breeze

Completed

Vibration Response Imaging (VRI) in Patients That Are Undergoing Pulmonary Interventional Procedure

Central Airway Stenosis

United States, France, Germany, Japan
Nagasaki University

Unknown

Oral Prednisolone in the Treatment of Esophageal Stricture After Esophageal Surgery

Esophageal Anastomotic Stricture

Japan
Osaka University

Unknown

The Impact of Higher Positive End Expiratory Pressure on Patient-Ventilator Asynchrony

Critical Illness

Japan
Abbott Medical Devices

Completed

ABSORB EXTEND Clinical Investigation (ABSORB EXTEND)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Cardiovascular Disease | Coronary Restenosis | Coronary Artery Stenosis

Netherlands, Taiwan, China, New Zealand, Singapore, France, United Kingdom, Austria, Israel, Italy, Malaysia, India, Poland, Sweden, Spain, South Africa, Canada, Australia, Japan, Argentina, Brazil, Switzerland, Belgium, Denmark, Germany

Clinical Trials on Critical Aortic Stenosis in Japan

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Singapore

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Rare Diseases

Drug Interventions

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