Clinical Trials on DNA Damage Repair Deficiency in France

Total 390 results

Assistance Publique - Hôpitaux de Paris

Recruiting

Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE) (ARTEGENE)

Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency

France
The Hospital for Sick Children
Bristol-Myers Squibb

Terminated

Pilot Study of Nivolumab in Pediatric Patients With Hypermutant Cancers

Refractory or Recurrent Hypermutated Malignancies | Biallelic Mismatch Repair Deficiency (bMMRD) Positive Patients

United States, France, Canada, Australia, Israel
Association Pour l'Aide a la Recherche en Immunologie...

Completed

Study Through Imaging of Visceral Lymphoid Organs in Patients With SCID Who Have Recieved Bone Marrow Allograft (LymphImaging)

Severe Combined Immunodeficiency

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

LIFSCREEN : Evaluation of Whole Body MRI for Early Detection of Cancers in Subjects With P53 Mutation (Li-Fraumeni Syndrome) (LIFSCREEN)

Li Fraumeni Syndrome

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Safety and Efficacy Study of Human T Lymphoid Progenitor (HTLP) Injection After Partially HLA Compatible Allogeneic Hematopoietic Stem Cell Transplantation in SCID Patients (HTLP Necker)

Pediatric Patients | Any Type of Severe Combined Immunodeficiency (SCID) | Partial HLA Incompatible Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

France
Assistance Publique - Hôpitaux de Paris

Completed

Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID2)

X-linked Severe Combined Immunodeficiency

France
Assistance Publique - Hôpitaux de Paris

Completed

CHROENDOHNPCC: Early Detection of Pre-cancer Lesions in Adults With Hereditary Nonpolyposis Colorectal Cancer Syndrome

Colorectal Neoplasms, Hereditary Nonpolyposis

France
Nantes University Hospital

Completed

Generalized Neonatal Screening of Severe Combined Immunodeficiencies (DEPISTREC)

Severe Combined Immunodeficiency, Atypical

France
University Hospital, Strasbourg, France

Recruiting

Metabolic Study of Cockayne Syndrome (METABO-CS)

Cockayne Syndrome

France
Centre Leon Berard

Withdrawn

A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts (EVAADE)

Myelodysplastic Syndromes | Severe Combined Immunodeficiency | Acute Leukemia | Haematological Malignancy | Hemoglobinopathy in Children | Bone Marrow Aplasia

France
Centre Leon Berard

Recruiting

Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation (EVAADE)

Myelodysplastic Syndromes | Severe Combined Immunodeficiency | Acute Leukemia | Haematological Malignancy | Hemoglobinopathy in Children | Bone Marrow Aplasia

France
University Hospital, Strasbourg, France

Recruiting

Growth Curves in Cockayne Syndrome Type 1 and Type 2 (Curves-CS)

Cockayne Syndrome, Type I and II

France
Direction Centrale du Service de Santé des Armées

Unknown

Epidemiological Description of the Kaposi's Disease in France's Southeast (KAPOSI-1)

Kaposi's Disease

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Faecal Microbiota Characterization in Lynch Syndrome (LS) Patients With or Without Colorectal Neoplasia (Microbiote)

Lynch Syndrome

France
French National Agency for Research on AIDS and...
Celgene Corporation

Terminated

Lenalidomide in Kaposi Disease Associated With HIV Infection (LENAKAP)

HIV Infection Associated Kaposi Disease

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Effect of Chemoprevention by Low-dose Aspirin of New or Recurrent Colorectal Adenomas in Patients With Lynch Syndrome (AAS-Lynch)

Lynch Syndrome

France
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Genetic Factors of Idiopathic Polypoidal Vasculopathies in the ATM Gene (Ataxia Telangiectasia Mutated) (ATM)

Choroidal Neovascularization

France
Assistance Publique - Hôpitaux de Paris
ARC Foundation for Cancer Research

Completed

NBI Versus Indigo Carmine During Colonoscopy in Lynch Syndrome (LYNCH-CHROMO)

Lynch Syndrome

France
Assistance Publique - Hôpitaux de Paris
EuroFancolen

Completed

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and Plerixafor (FancoMob)

Fanconi Anemia

France
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Lynch Syndrome | Stage III Colon Cancer AJCC v8 | Colon Adenocarcinoma | DNA Repair Disorder

United States, Puerto Rico, Germany
DNage B.V.

Terminated

Observational Study to Assess Natural History in Cockayne Syndrome Patients

Cockayne Syndrome

United States, France, United Kingdom
University Hospital, Lille

Completed

Predictive Factor Study of the Occurrence of Endometrial Cancer in Patients With Lynch Syndrome (PrediLynch)

Lynch Syndrome

France
Assistance Publique - Hôpitaux de Paris

Completed

Microcephaly Genetic Deficiency in Neural Progenitors (MICROFANC)

Microcephaly

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Microcephaly, Fanconi Anemia and Praxial Disorders (MicroFancII)

Fanconi Anemia

France
Bristol-Myers Squibb

Active, not recruiting

A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread (CheckMate142)

Microsatellite Stable Colorectal Cancer | Mismatch Repair Proficient Colorectal Cancer | Microsatellite Unstable Colorectal Cancer | Mismatch Repair Deficient Colorectal Cancer

United States, Australia, Belgium, Canada, Ireland, Italy, Spain, France
Centre Hospitalier de Cayenne

Recruiting

Precariousness and Sexual Vulnerability of People From Haiti Living With or Without HIV in French Guiana (ParcoursHaiti)

HIV Seropositivity

French Guiana
ANRS, Emerging Infectious Diseases
MCM Vaccines B.V.

Completed

Trial Comparing Three Strategies of Vaccination Against the Virus of Hepatitis B in HIV Infected Patients (VIHVAC-B)

HIV Infections

France
Centre Hospitalier de Cayenne

Recruiting

Study of Entry and Continuation in Care for People Living With HIV in French Guiana (EMVIH)

Human Immunodeficiency Virus

French Guiana
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France

Active, not recruiting

Covid-19 Vaccine Cohort in Specific Populations (COV-POPART)

Immune Deficiency

France
French National Agency for Research on AIDS and...

Completed

Accelerated Aging, HIV Infection, Antiretroviral Therapies (EP 45)

HIV Infection | Aging Accelerated | Antiretroviral Therapies

France
University Hospital, Strasbourg, France

Recruiting

Study of Neurological Damage From Coronavirus Disease (COVID-19) (NeuroBiomarK)

COVID-19

France
ANRS, Emerging Infectious Diseases
MCM Vaccines B.V.

Completed

Trial Comparing Two Strategies of Vaccination Against Hepatitis B in HIV-infected Patients Non Responding to Primary Immunization (B-BOOST) (B-BOOST)

HIV Infection | Hepatitis B

France
University Hospital Center of Martinique
Laboratoire Cerba

Completed

Influence of IL28B Genetic Variation on the Phenotype Infection of HTLV-1 (HAMIL28B)

HTLV-I Infections

Martinique
NEAT ID Foundation
PENTA Foundation; European Commission; VERDI Consortium

Recruiting

Morbidity, Mortality And Risk Factors of Mpox in HIV Negative High Risk Sexual Health Clinic Attenders and People Living With HIV (MASH 1)

Monkeypox | HIV Coinfection

Spain, France, Poland, United Kingdom
French National Agency for Research on AIDS and...

Completed

Cohort of Young Adults Infected With HIV Since Birth or During Childhood (CO19 COVERTE)

HIV Infection | Young Adult

France
ELHARRAR Xavier

Unknown

Prone Positioning in Spontaneously Breathing Nonintubated Covid-19 Patient: a Pilot Study (ProCov)

Coronavirus Infection | Oxygen Deficiency

France
University Hospital, Bordeaux

Completed

Exploring Brain Damages After COVID-19 Infection (BRAINCOV)

SARS-CoV 2

France
Centre Hospitalier Universitaire, Amiens

Active, not recruiting

Study of Morphological, Spectral and Metabolic Manifestations of Neurological Complications in Covid-19 Patients (NSpectroCovid)

Covid19 | Brain Damage | Neurological Manifestations

France
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Revealing Increased Axonal Loss in Treated HIV Patients (OCTIHIV)

HIV Seropositivity

France
Hopital Lariboisière

Completed

Antiretroviral Therapy and Extreme Weight (EXTATIC)

HIV Infection

France
Centre de Recherches et d'Etude sur la Pathologie...

Recruiting

HIV-1 Infected Patients, Phase II Trial, Dual Combination Doravirine/Raltegravir Open Label (DORAL)

HIV Infections

France
Centre de Recherches et d'Etude sur la Pathologie...

Active, not recruiting

Adipose Tissue After Switch to Doravirine (ADDORE)

HIV Infections

France
ANRS, Emerging Infectious Diseases

Completed

A Chronological Study of the Formation of HIV Cellular Reservoirs Through the Expression of Surface Markers on CD4 + T Lymphocytes, Including CD32a (ANRS EP63)

HIV Infections

France
French National Agency for Research on AIDS and...
Tibotec Pharmaceutical Limited

Completed

Study Comparing Efficacy and Safety of Darunavir Boosted With Ritonavir to HART With 2 NRTI and Darunavir Boosted With Ritonavir in HIV-1 Infected Patients ANRS136

HIV Infections

France
Gilead Sciences

Completed

TOTEM: Switch From Other Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to Once Daily Truvada (TOTEM)

HIV Infections

France
Assistance Publique - Hôpitaux de Paris

Suspended

Bioequivalence Study of Didanosine in Children Treated for HIV (ddI)

HIV Infections

France
French National Agency for Research on AIDS and...

Completed

Long-Term Supervised Treatment Interruption in HIV-Infected Patients

HIV Infections

France
French National Agency for Research on AIDS and...
Hoffmann-La Roche

Terminated

Evaluation of Therapeutic Drug Monitoring of Protease Inhibitors on Virologic Success and Tolerance of Highly Active Antiretroviral Therapy (HAART)

HIV Infections

France
French National Agency for Research on AIDS and...
Gilead Sciences; Abbott

Completed

Evaluation of a Lopinavir/Ritonavir Monotherapy vs a Triple Therapy as Maintenance Regimens in HIV-1 Infected Patients (ANRS 140 DREAM)

HIV Infections

France
ANRS, Emerging Infectious Diseases
Abbott

Completed

Prevention of HIV1 Mother to Child Transmission Without Nucleoside Analogue Reverse Transcriptase Inhibitors in the Pre-partum Phase. ANRS 135 Primeva

HIV Infections

France

Clinical Trials on DNA Damage Repair Deficiency in France

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