Clinical Trials on Difficult to Heal Wounds

Total 1848 results

Maisonneuve-Rosemont Hospital

Completed

Survival of Peritoneal Mesothelioma After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy (HIPEC)

Peritoneal Mesotheliomas

Canada
Poitiers University Hospital

Completed

Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia

Acute Myeloid Leukemia | Febrile Neutropenia | Bloodstream Infection

France
Fatih Sultan Mehmet Training and Research Hospital

Completed

Efficacy of Shortwave Diathermy in Ulnar Nerve Entrapment on the Elbow

Ulnar Nerve Entrapment at Elbow

Turkey
DePuy Orthopaedics

Recruiting

Actis Total Hip System 2 Year Follow-up (Actis14014)

Osteoarthritis | Rheumatoid Arthritis | Congenital Hip Dysplasia | Traumatic Arthritis | Avascular Necrosis of the Femoral Head | Acute Traumatic Fracture of the Femoral Head or Neck | Certain Cases of Ankylosis | Non-union of Femoral Neck Fractures | Certain High Sub-Capital & Femoral Neck Fractures...

United States
Corin

Active, not recruiting

Corin MiniHip and Trinity Cup Clinical Surveillance Study

Developmental Dysplasia of the Hip | Osteoarthritis, Hip | Total Hip Arthroplasty | Avascular Necrosis of the Femoral Head | Rheumatoid Arthritis of Hip | Traumatic Arthritis of Hip
Amgen

Completed

Prospective Observational Study of Febrile Neutropenia (FN) and Pegfilgrastim Primary Prophylaxis in Breast Cancer and Non-Hodgkin's Lymphoma Patients Receiving High (>20%) FN-risk Chemotherapy

Chemotherapy-induced Febrile Neutropenia

Belgium, Poland, Germany, Czechia, Austria, France, Greece, Romania, Bulgaria
Mark Dewhirst

Completed

Mitomycin C With Hyperthermia and Intravesical Mitomycin C to Treat Recurrent Bladder Cancer

Transitional Cell Carcinoma of Bladder | Superficial Bladder Cancer

United States
Arthrex, Inc.

Recruiting

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

Hyperpronated Foot | Reconstruction Surgeries of the Foot | Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle | Fixation of Small Bone Fragments of the Foot/Ankle | Lisfranc Arthrodesis | Mono or Bi-cortical Osteotomies in the Forefoot | First Metatarsophalangeal Arthrodesis and other conditions

Germany, United States, South Africa
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Withdrawn

KeraStat Skin Therapy in Treating Radiation Dermatitis in Patients With Newly Diagnosed Stage 0-IIIA Breast Cancer

Stage IIIA Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Ductal Breast Carcinoma in Situ | Skin Reactions Secondary to Radiation Therapy

United States
University of Kansas Medical Center

Recruiting

Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis

ColoRectal Cancer | Cancer, Appendiceal

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Comparison Between Laparoscopic Ovarian Diathermy and Clomiphene Citrate in Women With Anovulatory PCOS

Polycystic Ovary Syndrome

United Kingdom
Zimmer Biomet

Terminated

Outcomes Study of the TM Humeral Stem Used in Primary, Total or Hemi Shoulder Arthroplasty

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Ununited Humeral Head Fracture | Irreducible 3- and 4-part Proximal Humeral Fractures

United States
Centre Hospitalier Universitaire de Nice

Terminated

Intra Peritoneal Chemo Hyperthermia (IPCH) : Cellular and Metabolic Consequences (CHIP)

Peritoneal Carcinomatosis From Colorectal or Ovarian Origin

France
ThermoFisher Scientific Brahms Biomarkers France

Completed

Biomarkers Correlation With Volemia (ENVOL)

Renal Insufficiency | Cerebral Hemorrhage | Head Injury | Non Traumatic Post Surgery | Poly Trauma Patients Without Heart Failure

France
University of Pisa

Unknown

Study on the Incidence of Febrile Episodes During Stem Cells Collection After Chemotherapy in Patients With Multiple Myeloma

G-CSF, Multiple Myeloma, Febrile Episode, Filgrastim, Leograstim
Australian and New Zealand Intensive Care Research...
The Alfred

Not yet recruiting

Trial of ECMO to De-Sedate, Extubate Early and Mobilise in Hypoxic Respiratory Failure (REDEEM)

Pneumonia | Extracorporeal Membrane Oxygenation | Mechanical Ventilation Complication | Hypoxemia | COVID-19 Respiratory Infection | Acute Respiratory Distress Syndrome Due to COVID-19

Australia, Germany
Dr Caeymaex Laurence
Ministry of Health, France; Paris 12 Val de Marne University

Completed

SEPREVEN: a Stepped-wedge Randomised Controlled Trial (SEPREVEN)

Nosocomial Pneumonia | Extravasation Injury | Skin Lesion | Intubation Complication | Intensive Care Units, Neonatal | Misadventures to Patients During Surgical and Medical Care | Catheter-related Bloodstream Infection (CRBSI) Nos | Quality of Healthcare | Ventilator Adverse Event | Immature Newborn | Nasal... and other conditions

France
Hospital Universitario Ramon y Cajal

Recruiting

Pulmonary Inflammation in COVID-19 ARDS (IMPU-COVID)

COVID-19 Acute Respiratory Distress Syndrome | ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2

Spain
QuantalX Neuroscience

Completed

Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.

Healthy | Hemorrhage | Cognitive Impairment | Dementia | Fibromyalgia | TBI (Traumatic Brain Injury) | Cognitive Decline | Concussion, Brain | MS (Multiple Sclerosis) | Adhd | CVA | ABD | Mci

Israel
RenJi Hospital

Recruiting

Probiotics Attenuate Postoperative Cognition Decline

Knee Osteoarthritis | Lumbar Disc Herniation | Necrosis of Femoral Head | Fracture of Neck of Femur

China
Medacta International SA

Active, not recruiting

Prospective Study for the Evaluation of the Cementless Anatomic Femoral Stem Minimax -Launay

Rheumatoid Arthritis | Avascular Necrosis | Congenital Hip Dysplasia | Primary Osteoarthritis | Secondary Osteoarthritis | Traumatic Arthritis | Fracture; Femur, Head

France
University Hospital, Montpellier

Completed

Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children

Hirschsprung Disease | Febrile Urinary Tract Infection (Disorder)

France
Novartis Pharmaceuticals

Completed

An Extention Study of Safety of Canakinumab in Japanese Patients With Periodic Fever Syndromes

Periodic Fevers Syndrome

Japan
Pfizer

Terminated

A Study to Evaluate the Efficacy of Somatropin in Adults With Growth Hormone Deficiency Caused by Trauma and/or Head Injury (GHD)

Brain Injuries | Growth Hormone Deficiency Dwarfism

United States
Stryker Trauma GmbH

Recruiting

Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study (SiD)

Rotator Cuff Tears | Shoulder Deformity | Osteoarthritis Shoulder | Avascular Necrosis of the Head of Humerus | Rheumatoid Arthritis Shoulder | Fracture, Humeral | Traumatic Arthritis of Right Shoulder Region (Diagnosis)

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Unknown

Treatment of Bevacizumab Followed by Steroid in RN

Brain Injuries | Nasopharyngeal Carcinoma | Adverse Effect of Radiation Therapy

China
ThermalCore Inc

Suspended

A Phase 1 Trial of Perfusion Induced Systemic Hyperthermia (PISH) Over Multiple Cycles for Terminal Ovarian Cancer (PISH-2)

Ovarian Cancer

United States
Universitaire Ziekenhuizen KU Leuven

Recruiting

Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed (HIPEC)

Pseudomyxoma Peritonei | Peritoneal Carcinomatosis | Peritoneal Mesothelioma

Belgium
Hospices Civils de Lyon

Unknown

Tolerance of Intraperitoneal (IP) Nivolumab After Extensive Debulking Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Ovarian Carcinoma (ICONIC)

Ovarian Cancer

France
The Netherlands Cancer Institute

Completed

Secondary Debulking Surgery +/- Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer

Ovarian Cancer

Netherlands
Ludwig-Maximilians - University of Munich

Unknown

Combination Chemotherapy With or Without Whole-Body Hyperthermia in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

Germany, Netherlands, Hungary
Rennes University Hospital

Terminated

Study of Povidone Iodine to Reduce Pulmonary Infection in Head Trauma and Cerebral Hemorrhage in Intensive Care Unit (SPIRIT-ICU)

Ventilator Associated Pneumonia

France
The University of Texas Health Science Center,...

Unknown

Whole Body Hyperthermia Combined With Chemotherapy in Treating Patients With Metastatic Breast, Ovarian, Endometrial, or Cervical Cancer

Cervical Cancer | Breast Cancer | Ovarian Cancer | Endometrial Cancer

United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer. (Ronco-Onco)

Snoring | Sleep Apnea | Oral Cancer | Oral Squamous Cell Carcinoma | Pharynx Cancer

Canada
University College, London

Recruiting

Cancer Treatment Related Cardiovascular Toxicity: Comprehensive Myocardial and Vascular Phenotyping (PC-TOX)

Cardiovascular Diseases | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Cardiotoxicity | Malignancy | Oesophagus Cancer | Fluorouracil Adverse Reaction

United Kingdom
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Phase I Dose-finding Trial of Hyperthermic Intraperitoneal Paclitaxel Combined With Cisplatin

Ovarian Cancer | Paclitaxel | Hyperthermic Intraperitoneal Chemotherapy

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Efficacy of Neoadjuvant Hyperthermic Intraperitoneal Chemotherapy in Advanced High-grade Serous Ovarian Cancer (the NHIPEC Trial) (NHIPEC)

Neoadjuvant Chemotherapy | Hyperthermic Intraperitoneal Chemotherapy

China
Centre Oscar Lambret

Recruiting

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer (CHIPPI) (CHIPPI)

Ovarian Cancer | Ovarian Carcinoma | Ovary Neoplasms

France, Belgium
National Human Genome Research Institute (NHGRI)
Merck Sharp & Dohme LLC; Duke University; University of Massachusetts, Worcester

Recruiting

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

Fever | Genetic Diseases | Familial Mediterranean Fever (FMF) | Autoinflammation | Periodic Fever | ROSAH | ALPK1

United States
Jonathan Kiev
Exatherm, Inc

Completed

Perfusion-Induced Hyperthermia for Metastatic Carcinoma

Solid Tumor, Adult | Metastatic Non-Small Cell Lung Carcinoma

United States
Second Affiliated Hospital, School of Medicine,...
Zhejiang University

Recruiting

HIPEC in the Treatment of Stage IIc-IV Epithelial Ovarian Cancer After CRS (HIPECOC)

Ovarian Cancer | Hyperthermic Intraperitoneal Chemotherapy

China
Zimmer Biomet

Active, not recruiting

Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Revision Total Shoulder Arthroplasty | Ununited Humeral Head Fracture | Irreducible 3-and 4-part Proximal Humeral Fractures | Gross Rotator Cuff Deficiency

United States, United Kingdom
Zimmer Biomet

Active, not recruiting

AVANTAGE® RELOAD Double Mobility Acetabular Cup -Clinical Study

Femoral Neck Fracture | Congenital Hip Dysplasia | Primary Osteoarthritis | Post-Traumatic Arthritis | Inflammatory Joint Disease | Femoral Head Necrosis | Sequelae From Previous Hip Surgery | Osteotomies

France, Slovenia
Peter MacCallum Cancer Centre, Australia
Melbourne Health; Westmead Hospital; Victorian Infectious Diseases Reference...

Completed

PET/CT and Bacterial/Fungal PCR in High Risk Febrile Neutropenia (PIPPIN)

Acute Myeloid Leukemia | Febrile Neutropenia | Acute Lymphoblastic Leukemia | Haematopoietic Stem Cell Transplant, Autologous | Haematopoietic Stem Cell Transplant, Allogeneic

Australia
Providence VA Medical Center
University of Alabama at Birmingham; United States Department of Defense; Brown... and other collaborators

Active, not recruiting

Neuroimaging Biomarker for Seizures (NIBMSZS)

Epilepsy | Traumatic Brain Injury | Magnetic Resonance Imaging | Conversion Disorder | Head Injury | Seizure Disorder | Non-Epileptic Seizure | Seizure Disorder, Post Traumatic

United States
Fujian Medical University

Unknown

Effect of Reversed Tracking Method for Identification of EBSLN in Thyroid Surgery

Thyroid Cancer | Recurrent Laryngeal Nerve Injuries

China
University Hospital, Bonn

Unknown

Safety and Pharmacokinetics of Intraoperative Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) With Cisplatin to Treat Platinum-sensitive Recurrent Ovarian Cancer (HIPEC ROC I)

Ovarian Cancer

Germany
Aesculap AG

Active, not recruiting

Plasmafit® Revision Structan® Hip Endoprosthesis Cup

Arthroplasty Complications | Prosthesis Failure | Osteolysis | Degenerative Osteoarthritis | Rheumatic Arthritis | Fractures, Hip | Instability of Prosthetic Joint | Femoral Head Avascular Necrosis

Germany
Washington State University
National Institute of Allergy and Infectious Diseases (NIAID); Washington University... and other collaborators

Recruiting

RVF and Other Emerging Infectious Diseases in East and Central Africa

Hemorrhagic Fevers, Viral | Rift Valley Fever

Congo, The Democratic Republic of the, Kenya, Tanzania, Uganda
UMC Utrecht
Center for Translational Molecular Medicine; Dutch Cancer Society; Vrienden UMC...

Recruiting

Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer (i-GO)

Breast Cancer | Breast Neoplasms | Metastatic Cancer | Metastatic Breast Cancer | Stage IV Breast Cancer | Invasive Ductal Breast Cancer | Invasive Ductal Carcinoma of Female Breast | Adenocarcinoma Breast

Netherlands

Clinical Trials on Difficult to Heal Wounds

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations