Clinical Trials on Drug-resistant in Ireland

Total 125 results

University College Cork

Completed

Prevention of Adverse Drug Events (ADEs) in Hospitalised Older Patients

Adverse Drug Reaction

Ireland
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
University College Cork
University of East Anglia; Hospital Universitario Ramon y Cajal; University Ghent and other collaborators

Completed

Clinical Trial of a New Software ENgine for the Assessment & Optimization of Drug and Non-drug Therapy in Older peRsons (SENATOR)

Adverse Drug Reactions

Ireland
University College Cork

Completed

Adverse Drug Event Prevention Using Structured Pharmacist Review

Adverse Drug Reactions

Ireland
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
COMPASS Pathways

Completed

The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression

Treatment Resistant Depression

United States, Ireland
University of Limerick

Unknown

Protein Supplementation and Recovery of Muscle Function

Muscle Damage | Resistance Training

Ireland
GH Research Ireland Limited

Recruiting

A Trial of GH001 in Patients With Treatment-resistant Depression

Treatment-resistant Depression

Ireland, Germany, Czechia, Spain, Netherlands, Poland
Brown University
National Institute on Drug Abuse (NIDA)

Completed

The Rhode Island Prescription and Illicit Drug Study (RAPIDS)

Drug Overdose | Opioid Overdose

United States
University College Cork

Unknown

Discontinuation of Long-term Medications in Older People Entering Nursing Home Care (STOPPFrail)

Frail Elderly Syndrome | Drug-Related Side Effects and Adverse Reactions | Polypharmacy | Inappropriate Prescribing

Ireland
Brown University
National Institute on Drug Abuse (NIDA); New York University

Active, not recruiting

Preventing Overdose Using Information and Data From the Environment (PROVIDENT)

Drug Overdose | Opioid Overdose

United States
Jørgen Bjerggaard Jensen
Odense University Hospital; Karolinska University Hospital; Zealand University... and other collaborators

Recruiting

NORTH-REG Dwell-Time Study

Side Effect of Drug

Denmark, Sweden, Iceland
Butler Hospital
National Institute of General Medical Sciences (NIGMS)

Recruiting

Exercise to Augment TMS in Those With Treatment Resistant Depression

Treatment Resistant Depression

United States
Helsinki University Central Hospital
Tampere University Hospital

Enrolling by invitation

Feasibility of Switching Fluoropyrimidine Due to Cardiotoxicity Study (CardioSwitch)

Solid Tumor

Denmark, Norway, Sweden, Finland, Netherlands, Iceland, Ireland
University College Dublin
Enterprise Ireland

Completed

The Role of Milk Derived Peptides on Glycaemic Control

Insulin Resistance

Ireland
COMPASS Pathways

Completed

Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)

Treatment Resistant Depression

United States, Czechia, Netherlands, United Kingdom, Ireland
University College Dublin
University of Oslo; Uppsala University; Institut National de la Santé Et de la... and other collaborators

Completed

The Effect of Dietary Fat Modification on Risk Factors Associated With the Metabolic Syndrome

Metabolic Syndrome

Ireland
Massachusetts General Hospital
National Institute of Mental Health (NIMH); Temple University; Butler Hospital; University of Kansas and other collaborators

Terminated

Proof-of-Concept Trial of CERC-501 Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (RAPID KOR)

Treatment Resistant Depression

United States
Neurovalens Ltd.
University College Dublin; Exploristics Ltd; Compliance Solutions Ltd.

Completed

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Reducing Excess Body Weight

Obesity | Overweight | Metabolic Syndrome | Overweight and Obesity | Overweight or Obesity

Ireland
MedtronicNeuro

Completed

Reclaim Deep Brain Stimulation Clinical Study for Treatment-Resistant Depression

Depression

United States
Centre Hospitalier Universitaire de la Réunion

Unknown

Community Epidemiology and Typology of Third-generation Cephalosporins Resistant Enterobacteriaceae in Reunion Island (AB-RUN)

Bacterial Resistance

Réunion
Queen's University, Belfast

Completed

Effect of Fruit and Vegetables on Insulin Resistance (FIRST)

Cardiovascular Disease

United Kingdom
Health Service Executive, Ireland

Recruiting

Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study. (D-FOREST)

Personality Disorders | Cardiovascular Diseases | Obesity | Schizophrenia | Frailty | Recovery | Psychosis | Violence | Type II Diabetes | Treatment-resistant Schizophrenia | Forensic Psychiatry | Outcome Measure

Ireland
Neurovalens Ltd.
University College Dublin; Exploristics Ltd; Compliance Solutions Ltd.

Completed

Effect of VeSTAL Device in Type 2 Diabetes Mellitus

Metabolic Syndrome | Type 2 Diabetes

Ireland
COMPASS Pathways

Recruiting

Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD

Treatment Resistant Depression

United States, Spain, Ireland, France, United Kingdom, Canada
Renal Dynamics GmbH
Biosensors Europe SA; Physio-Logic Ltd. Israel; AmeRuss Clinical Trials LLC, USA

Unknown

A Study to Evaluate Safety and Efficacy of the Redy™ Renal Denervation System in the Treatment of Patients With Uncontrolled Hypertension

Hypertension Resistant to Conventional Therapy

Israel, Belgium, Germany, Hungary, Ireland, Poland, Russian Federation, Serbia
University Hospital Inselspital, Berne
UMC Utrecht; Cliniques universitaires Saint-Luc- Université Catholique de Louvain and other collaborators

Completed

OPtimising thERapy to Prevent Avoidable Hospital Admissions in the Multimorbid Older People (OPERAM)

3 or More Chronic Conditions for 6 Months or Longer | 5 or More Regular Drugs

Belgium, Ireland, Netherlands, Switzerland
National University of Ireland, Galway, Ireland
Clinical Research Facility Galway; CORRIB Research Centre for Advanced Imaging...

Recruiting

Understanding CARdiac Events in Breast Cancer (UCARE)

Heart Failure | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Chemotherapeutic Toxicity | Oncology

Ireland
Galway Clinic

Unknown

Fasting Mimicking Diet in Prostate Cancer and Metabolic Syndrome

Metabolic Syndrome | Prostate Cancer | Intermittent Fasting

Ireland
University Hospital Inselspital, Berne
UMC Utrecht; Cliniques universitaires Saint-Luc- Université Catholique de Louvain and other collaborators

Completed

Health Economic Evaluation Alongside the OPERAM Trial

3 or More Chronic Conditions for 6 Months or Longer | 5 or More Regular Drugs

Belgium, Ireland, Netherlands, Switzerland
COMPASS Pathways

Completed

The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression (P-TRD)

Treatment Resistant Depression

United States, Netherlands, Ireland, Germany, United Kingdom, Canada, Czechia, Denmark, Portugal, Spain
Queen's University, Belfast
Northern Ireland Chest Heart and Stroke; HSC Research & Development Division... and other collaborators

Completed

Effect of Vitamin D3 Supplementation on Insulin Resistance- The DIR Study

Insulin Resistance | Pre-diabetes | Sub-optimal Vitamin D Status

United Kingdom
Cyberonics, Inc.

Completed

Study Comparing Outcomes for Patients With Treatment Resistant Depression Who Receive VNS Therapy at Different Doses

Depression

United States
Renaissance RX
Syntactx

Unknown

Diagnosing Adverse Drug Reactions Registry (DART)

Genetics of Drug Metabolism

United States
A-Mansia Biotech S.A.

Completed

Effect of Pasteurized Akkermansia Muciniphila on Insulin Resistance in Otherwise Healthy Subjects With Dysglycaemia

Metabolic Syndrome | Overweight and Obesity | Pre-diabetes

Ireland, Germany
University of Rhode Island

Recruiting

Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents

Alcohol Drinking | Tobacco Use | Drug Use

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Treatment of Acute Lymphoblastic Leukemia in Children

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
LNC THERAPEUTICS
Biofortis Mérieux NutriSciences; StatistiCal BV Wassenarr, The Netherland represented...

Completed

Efficacy of STABLOR® on Visceral Fat Mass Reduction in Patients With Metabolic Syndrome (OBEMINALE2)

Metabolic Syndrome

France, Ireland
Synspira, Inc.

Terminated

A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis

Lung Diseases | Cystic Fibrosis | Pulmonary Disease | Antibiotic Resistant Infection | Respiratory Tract Disease | Cystic Fibrosis Pulmonary Exacerbation | Lung Inflammation | Burkholderia Infections | Lung Infection | Multi-antibiotic Resistance | Pulmonary Inflammation | Lung Infection Pseudomonal | Cystic Fibrosis... and other conditions

United Kingdom
Royal College of Surgeons, Ireland
Steroid Metabolism Analysis Core, University of Birmingham; Institute of Systems...

Not yet recruiting

Exploring the Relationship Between Androgen Metabolism, Metabolic Disease and Skeletal Muscle Energy Balance in Men (MMetdMH)

Cardiovascular Diseases | Obesity | Diabetes | Metabolic Syndrome | Prostate Cancer | NAFLD | Metabolic Disturbance | Metabolic Disease | Hypogonadism, Male | Testosterone Deficiency | Androgen Deficiency

Ireland
Ruairí Floyd
Tallaght University Hospital

Recruiting

Time-restricted Eating to Improve Metabolic Abnormalities in Polycystic Ovarian Syndrome (TimeMAP)

Insulin Resistance | Hyperinsulinemia | PCOS

Ireland
E-Star BioTech, LLC
Mayo Clinic; Integrium

Completed

Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects (DTC/RHS)

Resistant Hypertension | Difficult to Control Hypertension

United States
Royal College of Surgeons, Ireland
University of Oxford; University of Birmingham

Recruiting

Dissecting the IMpact of 11-OXygenated and Classic Androgens on Skeletal Muscle Insulin Sensitivity (DIMOXIS) (DIMOXIS)

Endocrine System Diseases | Polycystic Ovary Syndrome | Insulin Resistance | Androgen; Hypersecretion

Ireland
Cancer Trials Ireland

Completed

CADY Study ICORG 08-01

Breast Cancer | Cardiac Toxicity

Ireland
Solvay Pharmaceuticals

Terminated

Fenofibrate and Metformin Insulin Sensitivity in Type 2 Diabetics Study

Type 2 Diabetes | Dyslipidemia

Finland, Ireland, Italy
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (TRANSFORM-1)

Treatment-resistant Depression

United States, France, Belgium, Mexico, Canada, Brazil, Estonia, Hungary, Slovakia
Janssen Research & Development, LLC

Completed

A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression (SUSTAIN-2)

Treatment-resistant Depression

United States, Australia, France, United Kingdom, Belgium, Germany, Taiwan, Spain, Argentina, Mexico, Poland, Bulgaria, Malaysia, South Africa, Turkey, Finland, Korea, Republic of, Brazil, Austria, Sweden, Lithuania
Baystate Medical Center
National Institute on Drug Abuse (NIDA); The Miriam Hospital; Boston Medical... and other collaborators

Completed

Prescribe to Save Lives (PTSL)

Opioid-Related Disorders | Drug Overdose

United States
Brown University

Completed

Rapid Self-Testing to Prevent Fentanyl Overdose Among Young People Who Use Drugs (RAPiDS2)

Accidental Overdose of Opiate

United States

Clinical Trials on Drug-resistant in Ireland

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gambia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations