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Clinical Trials on Epidermolysis Bullosa Dystrophica

Total 48 results

NCT04520022

Completed

Safety and Effectiveness Study of Allogeneic Umbilical Cord Blood-derived Mesenchymal Stem Cell in Patients With RDEB

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT04491604

Recruiting

The Objective of This Study is to Compare the Efficacy and Safety of Beremagene Geperpavec (B-VEC) Topical Gel With That of Placebo for the Treatment of Dystrophic Epidermolysis Bullosa (DEB).

Conditions: Dystrophic Epidermolysis Bullosa; Recessive Dystrophic Epidermolysis Bullosa; Dominant Dystrophic Epidermolysis Bullosa
NCT04285294

Not yet recruiting

Molecular Signatures of Cutaneous Squamous Cell Carcinoma During Recessive Dystrophic Epidermolysis Bullosa

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT04227106

Recruiting

Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Conditions: Epidermolysis Bullosa; Recessive Dystrophic Epidermolysis Bullosa
NCT04213261

Recruiting

A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT04213703

Recruiting

A Pilot Study to Explore the Role of Gut Flora in Epidermolysis Bullosa

Conditions: Epidermolysis Bullosa; Epidermolysis Bullosa Simplex; Epidermolysis Bullosa Dystrophica
NCT04214002

Recruiting

The Natural History of Wounds in Patients With Dystrophic Epidermolysis Bullosa (DEB)

Conditions: Dystrophic Epidermolysis Bullosa; DEB - Dystrophic Epidermolysis Bullosa
NCT04186650

Enrolling by invitation

Ex Vivo Gene Therapy Clinical Trial for RDEB Using Genetically Corrected Autologous Skin Equivalent Grafts

Conditions: Epidermolysis Bullosa Dystrophica, Recessive
NCT04177498

Not yet recruiting

Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT04173650

Not yet recruiting

MSC EVs in Dystrophic Epidermolysis Bullosa

Conditions: Dystrophic Epidermolysis Bullosa
NCT04171661

Active, not recruiting

Self-Assembled Skin Substitute for the Treatment of Epidermolysis Bullosa

Conditions: Epidermolysis Bullosa Dystrophica
NCT04153630

Active, not recruiting

Safety Study and Preliminary Efficacy of Infusion Haploidentical Mesenchymal Stem Cells Derived From Bone Marrow for Treating Recessive Dystrophic Epidermolysis Bullosa

Conditions: Epidermolysis Bullosa Dystrophica, Recessive
NCT03942250

Completed

Uses of Irradiated Human Amniotic Membrane in the Treatment of Dystrophic Epidermolysis Bullosa Patients

Conditions: Epidermolysis Bullosa; Chronic Skin Ulcer
NCT03928093

Recruiting

Pregabalin Treatment for RDEB Pain and Itch

Conditions: Pain, Neuropathic; Itch; Epidermolysis Bullosa
NCT03786237

Recruiting

Rigosertib for RDEB-SCC

Conditions: Epidermolysis Bullosa Dystrophica; Squamous Cell Carcinoma
NCT03752905

Active, not recruiting

A Phase 1/2 Trial of PTR-01 in Adult Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT03605069

Recruiting

Topical QR-313 in Dominant Dystrophic Epidermolysis Bullosa (DDEB) or Recessive Dystrophic Epidermolysis Bullosa (RDEB) Due to Mutation(s) in Exon 73 of the COL7A1gene

Conditions: Epidermolysis Bullosa Dystrophica, Recessive; Epidermolysis Bullosa Dystrophica, Dominant
NCT03578029

Recruiting

Evaluation of the Safety and Efficacy Study of RGN-137 Topical Gel for Junctional and Dystrophic Epidermolysis Bullosa

Conditions: Junctional Epidermolysis Bullosa; Dystrophic Epidermolysis Bullosa
NCT03536143

Active, not recruiting

Topical Beremagene Geperpavec (KB103) Gene Therapy to Restore Functional Collagen VII for the Treatment of Dystrophic Epidermolysis Bullosa

Conditions: Dystrophic Epidermolysis Bullosa
NCT03529877

Recruiting

Allogeneic ABCB5-positive Stem Cells for Treatment of Epidermolysis Bullosa

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT03472287

Completed

To Evaluate the Pharmacokinetic of Diacerein and Rhein After Maximum Use in Patients With Epidermolysis Bullosa (EB)

Conditions: Epidermolysis Bullosa (EB); Epidermolysis Bullosa Simplex; Dystrophic Epidermolysis Bullosa; Junctional Epidermolysis Bullosa
NCT03392909

Recruiting

Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT03241628

Completed

Proof of Concept Study for a Dressing Glove

Conditions: Epidermolysis Bullosa Dystrophica
NCT03183934

Unknown status

A Follow-up Study to Evaluate the Efficacy and Safety of ALLO-ASC-DFU in ALLO-ASC-EB-101 Clinical Trial

Conditions: Dystrophic Epidermolysis Bullosa
NCT03012191

Completed

Gentamicin for RDEB

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT02984085

Active, not recruiting

Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With RDEB.

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT02810951

Active, not recruiting

A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Conditions: Epidermolysis Bullosa Dystrophica, Recessive
NCT02698735

Completed

Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) Nonsense Mutation Patients

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT02579369

Unknown status

Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Dystrophic Epidermolysis Bullosa

Conditions: Dystrophic Epidermolysis Bullosa
NCT02493816

Completed

Safety Study of Gene-modified Autologous Fibroblasts in Recessive Dystrophic Epidermolysis Bullosa

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT02323789

Unknown status

Mesenchymal Stromal Cells in Adults With Recessive Dystrophic Epidermolysis Bullosa

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT02286427

Unknown status

A Comparative Study of the Healing of Chronic Ulcers of Recessive Epidermolysis Bullosa : Dressing vs Amniotic Membrane

Conditions: Epidermolysis Bullosa Dystrophica, Recessive; Ulcer
NCT02178969

Completed

Short Term Observational Study in DEB Patients

Conditions: Dystrophic Epidermolysis Bullosa
NCT02004600

Withdrawn

Pilot Study Evaluating the Efficiency and the Tolerance of the PDT in the Treatment of Epidermal Dysplasia for Patients Affected by Hereditary DEB

Conditions: Dystrophic Epidermolysis Bullosa
NCT01874769

Unknown status

Study of Immune Tolerance and Capacity for Wound Healing of Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Conditions: Recessive Dystrophic Epidermolysis Bullosa
NCT01768026

Withdrawn

Prospective, Longitudinal Natural History Study in Dystrophic Epidermolysis Bullosa

Conditions: Dystrophic Epidermolysis Bullosa
NCT01716169

Completed

Treatment of Chronic and Non-Chronic Wounds in Patients With Recessive Dystrophic Epidermolysis Bullosa Using Helicoll Collagen Dressings Versus Standard of Care

Conditions: Epidermolysis Bullosa Dystrophica; Epidermolysis Bullosa
NCT01538862

Completed

Efficacy of Granulocyte Colony Stimulating Factor (GCSF) In Patients With Dystrophic Epidermolysis Bullosa

Conditions: Dystrophic Epidermolysis Bullosa
NCT01528306

Withdrawn

A Pilot Study of HP802-247 in Dystrophic Epidermolysis Bullosa

Conditions: Dystrophic Epidermolysis Bullosa
NCT01263379

Active, not recruiting

Gene Transfer for Recessive Dystrophic Epidermolysis Bullosa

Conditions: Epidermolysis Bullosa Dystrophica; Epidermolysis Bullosa
NCT01019148

Recruiting

Characteristics of Patients With Recessive Dystrophic Epidermolysis Bullosa

Conditions: Epidermolysis Bullosa Dystrophica
NCT00951964

Completed

Treatment of Epidermolysis Bullosa Dystrophica by Polyphenon E (Epigallocatechin 3 Gallate)

Conditions: Epidermolysis Bullosa Dystrophica
NCT00904163

Completed

Characteristics of Adult Patients With Recessive Dystrophic Epidermolysis Bullosa

Conditions: Epidermolysis Bullosa Dystrophica
NCT00881556

Unknown status

Allogeneic Stem Cell Transplantation (ALLOSCT) in Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Conditions: Epidermolysis Bullosa
NCT00587223

Terminated

Safety and Efficacy of Apligraf in Nonhealing Wounds of Subjects With Junctional or Dystrophic Epidermolysis Bullosa (EB)

Conditions: Epidermolysis Bullosa, Junctional; Epidermolysis Bullosa Dystrophica
NCT00533572

Terminated

Recessive Dystrophic Epidermolysis Bullosa Screening for Possible Gene Transfer

Conditions: Epidermolysis Bullosa Dystrophica
NCT00478244

Terminated

Allogeneic Hematopoietic Stem Cell Transplant For Epidermolysis Bullosa

Conditions: Epidermolysis Bullosa
NCT00014729

Completed

Phase I Study of Isotretinoin in Patients With Recessive Dystrophic Epidermolysis Bullosa

Conditions: Epidermolysis Bullosa

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Clinical Trials on Epidermolysis Bullosa Dystrophica