Clinical Trials on Familial Longevity

Total 1173 results

Recursion Pharmaceuticals Inc.

Recruiting

Evaluate REC-4881 in Patients With FAP (TUPELO)

Familial Adenomatous Polyposis

United States
Changhai Hospital

Not yet recruiting

Colorectal Adenoma Canceration in FAP

Familial Adenomatous Polyposis

China
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH) (BioHoFH)

Lipoprotein Lipase Deficiency | Inborn Error of Lipid Metabolism | Corneal Arcus

Germany, India, Sri Lanka
Postgraduate Institute of Medical Education and...

Unknown

To Compare the Efficacy of Combination Therapy vs Monotherapy for Pulmonary Arterial Hypertension in Systemic Sclerosis (BosSilSS)

Associated Pulmonary Arterial Hypertension

India
The Cleveland Clinic

Completed

Rilonacept for Treatment of Familial Mediterranean Fever (FMF)

Familial Mediterranean Fever

United States
Actelion

Completed

Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Canada, United Kingdom, Italy, United States, Netherlands, Australia, Austria, Belgium, France, Germany, Spain
University of Palermo

Recruiting

Can Gluten/Wheat or Other Foods be Responsible for FMF Attacks

Familial Mediterranean Fever | Non-celiac Gluten Sensitivity

Italy
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)

Idiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Pulmonary Arterial Hypertension Associated With Connective Tissue Disease

United States
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection

Systemic Juvenile Idiopathic Arthritis | Periodic Fever Syndrome

China
Vanderbilt University Medical Center

Enrolling by invitation

Visualization of the Papilla Through Use of the NuView Device in Patients With FAP (NuView)

Familial Adenomatous Polyposis

United States
Novartis Pharmaceuticals

Completed

An Extension Trial of Inclisiran in Participants With Cardiovascular Disease and High Cholesterol (ORION-3)

Type2 Diabetes | Familial Hypercholesterolemia | Atherosclerotic Cardiovascular Disease | Symptomatic Atherosclerosis

Germany, United Kingdom, Netherlands, United States, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers

Familial Adenomatous Polyposis

United States
National Cancer Institute (NCI)

Completed

Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01

Familial Adenomatous Polyposis

United States
Mirum Pharmaceuticals, Inc.

Completed

Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease

Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis

United States, Canada
Westfälische Wilhelms-Universität Münster
ICON plc

Unknown

Natural History of GACI With or Without ARHR2 or PXE

Pseudoxanthoma Elasticum | Generalized Arterial Calcification in Infancy | Autosomal Recessive Hypophosphatemic Rickets

Germany
Nova Scotia Health Authority
Atlantic Provinces Dermatology Association

Completed

The Use of Kineret (Anakinra) in the Treatment of Familial Cold Urticaria

Familial Cold Urticaria

Canada
French Cardiology Society

Completed

Observatory of Pulmonary Arterial Hypertension of Congenital Heart Disease (ItinerAir)

Pulmonary Arterial Hypertension of Congenital Heart Disease

France
Dr. Ersin Arslan Education and Training Hospital

Completed

Incidental Cancer in Familial Adenomatous Polyposis

Cancer

Turkey
Yonsei University

Completed

The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study

Familial Adenomatous Polyposis

Korea, Republic of
Kinderkrankenhaus auf der Bult

Completed

Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, Germany (Fr1dolin)

Type 1 Diabetes | Familial Hypercholesterolemia
Heart Care Foundation
Fondazione SISA

Completed

Prevalence of Familial Hypercholesterolaemia (FH) in Italian Patients With Coronary Artery Disease (POSTER)

Coronary Artery Disease

Italy
University of Wisconsin, Madison
United Therapeutics

Terminated

Cardiac Metabolic Remodeling After Pulmonary Vasodilator Therapy in Pulmonary Arterial Hypertension: A Pilot Study

Pulmonary Arterial Hypertension | Right-Sided Heart Failure

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Genetic Epidemiology of Hypertriglyceridemia

Cardiovascular Diseases | Coronary Disease | Hyperlipidemia, Familial Combined | Hyperlipoproteinemia Type iv
Indiana University

Completed

Effect of Dietary Protein Source on Phosphaturia, PTH and FGF23 in Patients With CKD 3 and 4

Chronic Kidney Disease

United States
ZonMw: The Netherlands Organisation for Health...
Cardiff University; University Medical Center Groningen; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) and other collaborators

Unknown

Implementation of Guidelines on Hereditary or Familial Colorectal Cancer (RISCO)

Colorectal Neoplasms, Hereditary Nonpolyposis
London North West Healthcare NHS Trust

Unknown

Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy

Familial Adenomatous Polyposis

United Kingdom
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders

Paralysis, Hyperkalemic Periodic | Paramyotonia Congenita | Hypokalemic Periodic Paralysis
Marmara University

Recruiting

Investigation of Autonomic Dysfunction in Patients With Familial Mediterranean Fever

Familial Mediterranean Fever | Autonomic Dysfunction

Turkey
University of Texas Southwestern Medical Center
Massachusetts General Hospital

Recruiting

Dystonia Genotype-Phenotype Correlation

Dystonia | Dystonia; Idiopathic | Dystonia, Primary | Dystonia, Secondary | Dystonia, Familial | Dystonia Disorder | Dystonias, Sporadic | Dystonia; Orofacial | Dystonia Lenticularis | Dystonia, Paroxysmal | Dystonia 6 | Dystonia 5 | Dystonia 8 | Dystonia 9 | Dystonia 19 | Dystonia 10 | Dystonia 11 | Dystonia 20 | Dystonia 12 | Dystonia... and other conditions

United States
Johns Hopkins University
Pentax Medical

Active, not recruiting

CryoBalloon Ablation for Treatment of Duodenal Adenomas (C2D2)

Familial Adenomatous Polyposis | Duodenal Adenomas

United States
Imperial College London
Fu Wai Hospital, Beijing, China

Completed

IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients

Pulmonary Arterial Hypertension | Iron Deficiency

United Kingdom, China, Germany
Inozyme Pharma

Not yet recruiting

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

Pseudoxanthoma Elasticum | Arterial Calcification | Gene Mutations | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency | Autosomal Recessive Hypophosphatemic Rickets Type 2
Mirum Pharmaceuticals, Inc.

Active, not recruiting

A Study to Evaluate the Safety and Tolerability of Maralixibat in Infant Participants With Cholestatic Liver Diseases Including Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille Syndrome (ALGS). (RISE)

Cholestatic Liver Disease | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis

United States, United Kingdom, France, Belgium, Poland, Brazil, Mexico
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Amlodipine/Atorvastatin (Caduet®) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)

Hypertension | Angina Pectoris | Hypercholesterolemia | Familial Hypercholesterolemia
Assistance Publique - Hôpitaux de Paris

Unknown

Musculoskeletal Ultrasound of the Ankles in Erysipelas-like Erythema of Familial Mediterranean Fever (ECHOPERY)

Erysipelas

France
Arcispedale Santa Maria Nuova-IRCCS

Completed

Endoscopic Papillectomy for Ampullary Adenomas (Papillectomy)

Familial Adenomatous Polyposis | Ampullary Adenoma
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hyperapo B and Coronary Heart Disease

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Obesity | Diabetes Mellitus | Hypercholesterolemia, Familial
Rambam Health Care Campus
Schneider Children's Hospital

Unknown

Controlled Ceasing of Colchicine Therapy in Familial Mediterranean Fever (FMF) Patients With Single MEFV (Mediterranean Fever) Gene Mutation

Familial Mediterranean Fever

Israel
National Heart, Lung, and Blood Institute (NHLBI)

Completed

NHLBI Type II Coronary Intervention Study

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Hypercholesterolemia, Familial
Mansoura University

Completed

Is Diverting Ileostomy Necessary in Stapled Ileoanal Pouch?

Ulcerative Colitis | Familial Adenomatous Polyposis
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University; National... and other collaborators

Recruiting

DCE MRI in Patients With Pancreatic Cancer

Pancreatic Adenocarcinoma | Familial Pancreatic Cancer | Pancreatic Intraductal Papillary-Mucinous Neoplasm

United States
Xijing Hospital of Digestive Diseases

Completed

Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride

Colorectal Adenomas

China
Mayo Clinic
National Institute of Neurological Disorders and Stroke (NINDS); National Institute...

Completed

Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS)

Familial Frontotemporal Dementia

United States, Canada
University of Alabama at Birmingham

Completed

MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.

REM Sleep Behavior Disorder | Movement Disorders (Incl Parkinsonism) | Tremor Familial Essential, 1

United States
University of Arizona
Lipedema Foundation

Unknown

Insight Into Subcutaneous Adipose Tissue Disorders (INSIGHT)

Lipedema | Dercum's Disease | Familial Multiple Lipomatosis | Madelung's Disease

United States
Prof. Evelien Dekker, MD, PhD
Dutch Digestive Diseases Foundation

Completed

Identifying Patients With Hereditary and Familial Colorectal Cancer by Using an Online Risk Tool (FR-QUENT)

Colorectal Cancer | Lynch Syndrome | Familial Colorectal Cancer
Inozyme Pharma

Not yet recruiting

Natural History Study of ENPP1 Deficiency and and the Early-onset Form of ABCC6 Deficiency

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency | ATP-Binding Cassette Subfamily C Member 6 Deficiency
University of Minnesota

Completed

FMBI With War-affected Families

War-Related Trauma | Intergenerational Trauma | Family Mindfulness-based Intervention in War-affected Families

United States
Novartis Pharmaceuticals

Completed

Clinical Outcomes and Safety: A Registry Study of Ilaris (Canakinumab) Patients (B-Confident)

Cryopyrin-associated Periodic Syndromes (CAPS) | Familial Cold Autoinflam Syn (FCAS) | Muckle-wells Syn (MWS) | Neonatal Onset Multisystem Inflam Disease (NOMID)

Switzerland, United States, Germany, Norway, Austria
University of Utah
National Cancer Institute (NCI)

Withdrawn

Exisulind in Preventing Polyps in Patients With Familial Adenomatous Polyposis

Colorectal Cancer | Small Intestine Cancer

Clinical Trials on Familial Longevity

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