Clinical Trials on Growth Hormone Deficiency in South Africa

Total 2445 results

Kirby Institute

Completed

Safety and Efficacy of Reduced Versus Standard Dose Efavirenz (EFV) Plus Two Nucleotides in Antiretroviral-naïve Adults. (ENCORE1)

HIV Infections

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Safety of and Immune Response to an HIV Vaccine in Healthy Adults

HIV Infections

Australia
Grifols Therapeutics LLC

Active, not recruiting

Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD) (SPARTA)

Pulmonary Emphysema in Alpha-1 PI Deficiency

United States, Australia, Denmark, New Zealand, Estonia, Poland, Russian Federation, Sweden, Brazil, Canada, France, Finland
Holdsworth House Medical Practice
Atomo Diagnostics

Completed

Performance and Usability Evaluation of the Atomo HIV Self-Test

HIV Infections

Australia
Kirby Institute
Hoffmann-La Roche

Completed

A 48-Week, Randomised, Study to Describe the Pharmacokinetic Profile and Durability of Atazanavir-Saquinavir-Ritonavir Once Daily and Describe the Pharmacokinetic Profile of Saquinavir-Ritonavir Using Saquinavir 500mg Formulation: the ASK-500 Study (ASK-500)

HIV Infections

Australia
PENTA Foundation
Institut National de la Santé Et de la Recherche Médicale, France; Program... and other collaborators

Active, not recruiting

A Randomised Trial of Dolutegravir (DTG)-Based Antiretroviral Therapy vs. Standard of Care (SOC) in Children With HIV Infection Starting First-line or Switching to Second-line ART

HIV Infection

United Kingdom, Spain, Portugal, South Africa, Thailand, Uganda, Germany, Zimbabwe
Janssen R&D Ireland

Completed

TMC125-TiDP2-C238: An Exploratory Pharmacokinetics, Safety and Anti-HIV Activity Study of Etravirine (ETR) When Given With Boosted Atazanavir (ATV/Rtv) at Two Different Doses and 1 Nucleoside Reverse Transcriptase Inhibitor (NRTI) in Treatment Experienced HIV Patients

HIV Infections | Acquired Immunodeficiency Syndrome

United States, France, Argentina, South Africa, Thailand
Avera McKennan Hospital & University Health Center

Withdrawn

A Placebo-Controlled, Randomized, Safety and Efficacy Study to Evaluate the Change in Hemoglobin A1c Levels in Type 2 Diabetic Subjects While Taking Nutralin

Diabetes

United States
Avera McKennan Hospital & University Health Center
Vintek, LLC

Completed

A Study to Evaluate Glucose and Insulin Response to Nutralin

Diabetes

United States
Novo Nordisk A/S

Completed

Effect of Different Insulin Administrations, All in Combination With Metformin, on Glycaemic Control in Subjects With Type 2 Diabetes Inadequately Controlled by Oral Anti-diabetic Drugs

Diabetes Mellitus, Type 2 | Diabetes

Morocco, Tunisia, Algeria, South Africa, Egypt
Takeda

Enrolling by invitation

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease

Alpha1-Antitrypsin Deficiency

United Kingdom, Germany, United States, Austria, Portugal
Pharming Technologies B.V.

Completed

Efficacy, Safety and Immunogenicity Study of Recombinant Human C1 Inhibitor for the Treatment of Acute HAE Attacks

Hereditary Angioedema

United States, Bulgaria, Canada, Hungary, Israel, Italy, Macedonia, The Former Yugoslav Republic of, Poland, Romania, Serbia, South Africa
Andrew Carr
Merck Sharp & Dohme LLC

Completed

Raltegravir Use as Nonoccupational Postexposure Prophylaxis (NPEP) in Men Who Have Sex With Men (RAL-NPEP)

HIV Infections | HIV Prevention

Australia
ViiV Healthcare
GlaxoSmithKline

Completed

Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects

HIV Infections | Infection, Human Immunodeficiency Virus

United States, Portugal, Russian Federation, Mexico, Argentina, South Africa, Puerto Rico
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of V114 in Children Infected With Human Immunodeficiency Virus (HIV) (V114-030/PNEU-WAY PED) (PNEU-WAY PED)

Pneumococcal Infections

South Africa, Thailand, Ukraine
Harokopio University
National and Kapodistrian University of Athens; Technische Universität Dresden and other collaborators

Unknown

Feel4Diabetes-study (Feel4Diabetes)

Obesity | Type 2 Diabetes

Greece
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study of Patients Who Develop HIV Infection After Enrolling in HIV Vaccine Trials or HIV Vaccine Preparedness Trials

HIV Infections

United States, South Africa, Peru, Brazil
Hoffmann-La Roche

Terminated

A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy (Veronica)

Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer

Canada, United States, United Kingdom, Australia, Germany
PENTA Foundation
Institut National de la Santé Et de la Recherche Médicale, France; MRC CTU... and other collaborators

Completed

Strategy for Maintenance of HIV Suppression With Once Daily Integrate Inhibitor+Darunavir/Ritonavir in Children (SMILE)

HIV Infection

United Kingdom, Spain, Argentina, France, Mexico, Portugal, South Africa, Switzerland, Thailand, Uganda, Ukraine
Grifols Therapeutics LLC

Enrolling by invitation

Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency (SPARTA-OLE)

Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency

United States, New Zealand, Denmark, Australia, Finland, Estonia, Canada, Poland, Russian Federation, Sweden, France
Kirby Institute

Completed

Raltegravir and Atazanavir Dosing Strategy Study (SPARTA)

HIV Infection

Australia
Medical University of South Carolina
National Institutes of Health (NIH)

Completed

Improving Medication Safety and CVD Risk Factor Control in Kidney Transplant Recipients

Cardiovascular Diseases | Diabetes Mellitus | Medication Adherence

United States
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide (Morning or Evening) in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin (GETGOAL-M)

Diabetes Mellitus, Type 2

United States, Canada, Romania, Russian Federation, Ukraine, Germany, Spain, Philippines, Czech Republic, Mexico, Croatia, Chile, Morocco, South Africa, Australia, Venezuela
ImmVirx Pty Ltd

Recruiting

Study of Intratumoral IVX037 in Patients With Advanced or Metastatic Solid Tumours

Colorectal Cancer | Ovarian Cancer | Gastroesophageal Cancer

Australia
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Safety of and Immune Response to Dolutegravir in HIV-1 Infected Infants, Children, and Adolescents

HIV Infections

United States, Botswana, Brazil, Kenya, South Africa, Tanzania, Thailand, Zimbabwe
Kirby Institute
Merck Sharp & Dohme LLC; amfAR, The Foundation for AIDS Research; Abbott

Completed

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen (SECOND-LINE)

HIV Infections

Taiwan, Australia, Argentina, Singapore, India, France, South Africa, Chile, Germany, Hong Kong, Ireland, Malaysia, Mexico, New Zealand, Nigeria, Peru, United Kingdom
Holdsworth House Medical Practice

Completed

RETRIeVE: ReversE TranscRiptase Inhibitor hiV Practice

HIV Positive

Australia
Baxalta now part of Shire

Completed

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

Alpha1-antitrypsin Deficiency

United States, Canada
University of Adelaide
Australian Catholic University; La Trobe University

Recruiting

What Or When to Eat to Reduce the Risk of Type 2 Diabetes (WOW)

Diet Quality | Time-restricted Eating

Australia
University of Adelaide

Completed

Intermittent Fasting for Metabolic Health, Does Meal Timing Matter?

Insulin Resistance | Type 2 Diabetes

Australia
Merck Sharp & Dohme LLC

Active, not recruiting

Oral ISL QM as PrEP in Cisgender Women at High Risk for HIV-1 Infection (MK-8591-022) (Impower-022)

Prophylaxis | Human Immunodeficiency Virus Type 1 | HIV-I

United States, South Africa, Uganda
Gerard Turino

Completed

Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency

Emphysema | Alpha 1-Antitrypsin Deficiency

United States, Canada
Sheffield Teaching Hospitals NHS Foundation Trust
Fluoptics Ltd, Grenoble, France

Completed

Near Infrared Fluorescent Imaging in Thyroid and Parathyroid Surgery With the Fluobeam(TM) System of Fluoptics

Primary Hyperparathyroidism

United Kingdom
Apollomics (Australia) Pty. Ltd.
Novotech (Australia) Pty Limited; Apollomics Inc. (formerly CBT Pharmaceuticals...

Completed

APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors

Solid Tumor | Microsatellite Instability | Mismatch Repair Deficiency | Cancer of Unknown Primary Site

Australia
TaiGen Biotechnology Co., Ltd.

Completed

Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections

Diabetic Foot Infections

Taiwan, United States, South Africa, Thailand
Agricultural University of Athens

Completed

Effects of Yogurt With Spirulina on Cardiometabolic Risk Markers

Hypertension | Dyslipidemias | PreDiabetes | Overweight and Obesity

Greece
Agricultural University of Athens

Completed

Effects of Biofunctional Orange Juice on Cardiometabolic Risk Markers

Hypertension | Dyslipidemias | Overweight and Obesity | Prediabetes

Greece
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability and Efficacy of ISIS-GCGRRx in Type 2 Diabetes

Type 2 Diabetes Mellitus

United States, South Africa
BeiGene

Terminated

Treatment of Metastatic Castration-Resistant Prostate Cancer With Homologous Recombination Deficiency

Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Homologous Recombination Deficiency (HRD)

United States, Australia, Puerto Rico, Spain
Grifols Therapeutics LLC

Withdrawn

Study Evaluating IGSC 20% Flexible Dosing in Treatment-Experienced and Treatment-Naive Subjects With Primary Immunodeficiency

Primary Immunodeficiency

United States
Keryx Biopharmaceuticals

Completed

Ferric Citrate in Managing Serum Phosphorus and Iron Deficiency in Anemic Chronic Kidney Disease (CKD) Subjects Not on Dialysis

Iron Deficiency Anemia | Iron Deficiency

United States
National Taipei University of Nursing and Health...

Completed

The Effect of Yoga for Stress Among HIV Patients in Indonesia

Human Immunodeficiency Virus

Indonesia
407 Doctors
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Unknown

Once Daily 3TC, Efavirenz and ddI for HIV Infection

HIV Infection | AIDS

Australia
Sanofi

Completed

baSal BoluS Therapy in patIenTs With TypE 1 Diabetes Mellitus (SUBSTITUTE)

Diabetes Mellitus, Type 1

Tunisia, South Africa, Algeria, Argentina, Brazil, Colombia, Kuwait, Mexico, Saudi Arabia
American Regent, Inc.
Duke Clinical Research Institute

Completed

Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency (HEART-FID)

Heart Failure | Iron-deficiency

United States, Canada, Australia, Bulgaria, Georgia, New Zealand, Latvia, Hungary, Poland, Czechia, Lithuania, Russian Federation, Ukraine
Grifols Therapeutics LLC

Completed

The Safety and Tolerability of Alpha-1 Modified Process (MP) In Subjects With Alpha-1-antitrypsin (AAT) Deficiency (STAMP)

Alpha 1-Antitrypsin Deficiency

United States, United Kingdom
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Patients With AIDS and AIDS-Related Complex

HIV Infections

United States
ViiV Healthcare
GlaxoSmithKline

No longer available

An Expanded Access Protocol for Subjects Who Have Completed Clinical Studies Involving Maraviroc

Infection, Human Immunodeficiency Virus

Belgium, Russian Federation, Italy, South Africa, Argentina, Switzerland, Poland
Dionyssiotis, Yannis, M.D.
University of Thessaly

Completed

Sarcopenia and Diabetes Mellitus (SARCoDM)

Sarcopenia

Greece
Sheffield Children's NHS Foundation Trust

Completed

Neonatal, Infant and Toddler Salivary Study (NITS Study) (NITS)

Adrenal Insufficiency

United Kingdom

Clinical Trials on Growth Hormone Deficiency in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Brazil

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations