Clinical Trials on Health Information Technology

Total 87786 results

SphinCS Lyso Gemeinnutzige UG (Haftungsbeschrankt)

Recruiting

Registry Gangliosidoses

Gangliosidoses | Galactosialidosis | Sialidosis | GM1 Gangliosidosis | Tay-Sachs Disease | Sandhoff Disease | Morquio B Disease | Gm2-Gangliosidosis, Variant B1 | GM2 Activator Deficiency

Germany
Culicchia Neurological Clinic
Flowonix Medical

Recruiting

Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)

Traumatic Brain Injury | Muscle Spasticity | CVA (Cerebrovascular Accident) | Cerebral Palsy, Spastic | MS (Multiple Sclerosis) | Injuries, Spinal Cord

United States
University Hospitals Cleveland Medical Center
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism

Parkinson Disease | Parkinsonism | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Dementia With Lewy Bodies

United States
Compugen Ltd

Recruiting

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Multiple Myeloma | Ovarian Cancer | Lung Cancer | Advanced Cancer | Colon Cancer | Plasma Cell Neoplasm | HNSCC | Microsatellite Stable Colorectal Carcinoma | MSS-CRC

United States
Vancouver Island Health Authority

Recruiting

Ceftriaxone as Home IV for Staph Infections

Abscess | Staphylococcal Infections | Diabetic Foot Infection | Osteomyelitis | Vertebral Osteomyelitis | CNS Infection | Septic Arthritis | Coagulase Negative Staphylococcal Infection

Canada
Rush University Medical Center

Completed

In-Home Care for Patients With PSP and Related Disorders

Multiple System Atrophy | Progressive Supranuclear Palsy | Corticobasal Syndrome | Dementia With Lewy Bodies | Atypical Parkinson Disease

United States
Loxo Oncology, Inc.
Eli Lilly and Company

Active, not recruiting

A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL

B-cell Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States, Korea, Republic of, Australia, Japan, United Kingdom, Italy, Poland, France, Switzerland, Sweden
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

Nausea | Constipation | Diarrhea | Purpura | Lymphadenopathy | Gastrointestinal Hemorrhage | Hepatomegaly | Primary Systemic Amyloidosis | Amorphous, Eosinophilic, and Acellular Deposit | Early Satiety | Macroglossia | Recurrent Primary Amyloidosis | Refractory Primary Amyloidosis

United States
GE Healthcare
PPD

Completed

A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients

Essential Tremor | Multiple System Atrophy (MSA) | Parkinsonian Syndrome | Parkinson Disease(PD) | Progressive Supranuclear Palsy (PSP)

China
University of Maryland, Baltimore
Gilead Sciences; University of Miami Sylvester Comprehensive Cancer Center

Active, not recruiting

1630GCC: Zydelig Maintenance in B-Cell Non-Hodgkin's Lymphoma After Autologous Stem Cell Transplantation

Follicular Lymphoma | B-cell Lymphoma | Waldenstrom Macroglobulinemia | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Non Hodgkin Lymphoma | Small Lymphocytic Lymphoma | Transformed Lymphoma | Indolent Lymphoma

United States
University of Iowa

Completed

Cool vs Room-temperature Artificial Tears

Eye Pain | Ocular Surface Disease | Cystoid Macular Edema | Central Retinal Vein Occlusion With Macular Edema | Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis) | Exudative Age-Related Macular Degeneration, Unspecified Eye | Dry Eye Sensation

United States
University of Nottingham

Completed

Vaccination Perception in Inflammatory Conditions - Flu, Pneumonia and COVID-19 (OPINION)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Inflammatory Bowel Diseases | Vasculitis | Psoriatic Arthritis | Ankylosing Spondylitis | Reactive Arthritis | Inflammatory Disease

United Kingdom
Center for Vascular Pathology, Moscow

Completed

A New Approach in Laser Surgery Using the Regenerative Solution in Children Diagnosed With Vascular Pathology (DOUBLE-SKIN)

Vascular Diseases | Port-Wine Stain | Sturge-Weber Syndrome | Vascular Malformation | Capillary Malformation-Arteriovenous Malformation | Vascular Tumor

Russian Federation
University of Liege
University Hospital, Ghent; AZ Sint-Jan AV; Cliniques universitaires Saint-Luc-... and other collaborators

Terminated

MSC and HSC Coinfusion in Mismatched Minitransplants

Lymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Myeloproliferative Disorders | Multiple Myeloma | Leukemia, Lymphoblastic, Acute | Hodgkin's Disease | Leukemia, Lymphocytic, Chronic | Leukemia, Myelocytic, Chronic

Belgium
Russian Academy of Medical Sciences

Completed

Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain Syndrome

Neurocognitive Disorders | Brain Ischemia | Delirium, Dementia, Amnestic, Cognitive Disorders | Organic Brain Syndrome, Nonpsychotic | Mental Disorder, Organic | Nonpsychotic Organic Brain Syndrome | Organic Mental Disorder | Encephalopathy, Post-Traumatic, Chronic | Encephalopathy, Ischemic

Russian Federation
Dr Caeymaex Laurence
Ministry of Health, France; Paris 12 Val de Marne University

Completed

SEPREVEN: a Stepped-wedge Randomised Controlled Trial (SEPREVEN)

Nosocomial Pneumonia | Extravasation Injury | Skin Lesion | Intubation Complication | Intensive Care Units, Neonatal | Misadventures to Patients During Surgical and Medical Care | Catheter-related Bloodstream Infection (CRBSI) Nos | Quality of Healthcare | Ventilator Adverse Event | Immature Newborn | Nasal... and other conditions

France
University of Pennsylvania

Terminated

Trial of Donor Lymphocyte Infusion (DLI) and Activated DLI Following Relapse After Allogeneic Stem Cell Transplant

Multiple Myeloma | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Hodgkin's Disease

United States
Case Comprehensive Cancer Center

Completed

Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Severe Aplastic Anemia

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Terminated

Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI); Duke University; Vitrolife; XVIVO...

Completed

Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability

Bronchiectasis | Emphysema | Pulmonary Fibrosis | Cystic Fibrosis | Alpha-1 Antitrypsin Deficiency | Pulmonary Hypertension | Chronic Obstructive Pulmonary Disease (COPD) | Sarcoidosis

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Flu Vaccine in Preventing Influenza Infection in Healthy Volunteers and in Patients Who Have Undergone Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
William Gahl, M.D.
National Human Genome Research Institute (NHGRI)

Completed

Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome

Pulmonary Fibrosis | Inborn Errors of Metabolism | Albinism | Oculocutaneous Albinism | Platelet Storage Pool Deficiency

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Implandata Ophthalmic Products GmbH

Completed

Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation

Congenital Glaucoma | Stevens-Johnson Syndrome | Graft vs Host Disease | Congenital Aniridia | Chemical Burns

Germany
National Institute of Neurological Disorders and...

Completed

Assessment of Patients With Multiple Sclerosis (MS)

Multiple Sclerosis | Vasculitis | Tropical Spastic Paraparesis | HTLV-I Infection | Herpesviridae Infection

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Shandong Provincial Institute of Dermatology and...
Shandong Provincial Hospital; Jinan Military General Hospital; Jinan Central... and other collaborators

Unknown

Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome

Psoriasis | Urticaria | Acne | Leprosy | Pneumocystis Pneumonia | Allergic Cutaneous Vasculitis | Bullous Skin Diseases | Sterile Pustulosis

China
London Health Sciences Centre

Completed

Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma

Lymphoma | Kidney Cancer | Breast Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Endometrial Cancer

Canada
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Caregiver Support in the Quality of Life of Patients Who Are Undergoing Donor Bone Marrow Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Psychosocial Effects of Cancer and Its Treatment

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

T-Cell-Depleted Allogeneic Stem Cell Transplantation After Immunoablative Induction Chemotherapy and Reduced-Intensity Transplantation Conditioning in Treating Patients With Hematologic Malignancies

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Amgen

Completed

Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates

Bone Metastases in Men With Hormone-Refractory Prostate Cancer | Bone Metastases in Subjects With Advanced Breast Cancer | Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Tacrolimus and Mycophenolate Mofetil in Preventing Acute Graft-Versus-Host Disease in Patients With Advanced Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Office of Rare Diseases (ORD)
Rare Diseases Clinical Research Network

Unknown

Identifying Characteristics of Bone Marrow Failure Syndromes

Myelodysplastic Syndromes | Purpura, Thrombocytopenic | Anemia, Aplastic | Red-Cell Aplasia, Pure | Bone Marrow Failure Syndromes | Hemoglobinuria, Paroxysmal | Leukemia, Lymphocytic

United States
Mayo Clinic

Completed

Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Multiple Sclerosis | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Uveitis | Vasculitis | Psoriasis | Graves Disease | Systemic Sclerosis | Celiac Disease | Crohn Disease | Type 1 Diabetes Mellitus | Myasthenia Gravis | Ulcerative Colitis | Dermatomyositis | Polymyositis | Vitiligo | Hepatitis, Autoimmune | Polymyalgia... and other conditions

United States
Catholic University of the Sacred Heart

Unknown

Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) in Ovarian Cancer Recurrence (HORSE)

First Recurrence of Ovarian Cancer

Italy
National and Kapodistrian University of Athens
Ioulia And Irene Tseti Pharmaceutical Laboratories S.A.

Completed

Assessing the Efficacy of a Hydrogen Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia Relief

Postoperative Pain | Dental Plaque | Wound Heal | Sjogren's Syndrome | Mouth Dryness | Gingival Inflammation | Biopsy Wound | Oral Dryness | Mouth; Wound

Greece
Maimónides Biomedical Research Institute of Córdoba

Completed

Role of Intraperitoneal Intraoperative Chemotherapy With Paclitaxel in the Surgical Treatment of Peritoneal Carcinomatosis From Ovarian Cancer. Hyperthermia Versus Normothermia

Peritoneal Carcinomatosis
Zhongnan Hospital

Active, not recruiting

Cytoreductive Surgery(CRS) Plus Hyperthermic Intraperitoneal Chemotherapy(HIPEC) With Lobaplatin in Advanced and Recurrent Epithelial Ovarian Cancer (HIPECOV)

Ovarian Neoplasms | Ovarian Cancer | Epithelial Ovarian Cancer | Ovarian Cancer, Epithelial | Hyperthermic Intraperitoneal Chemotherapy(HIPEC) | Ovary Neoplasm

China
Scott R. Plotkin, MD, PhD
Takeda; National Comprehensive Cancer Network; The Children's Tumor Foundation

Recruiting

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) (INTUITT-NF2)

Ependymoma | Meningioma | Neurofibromatosis Type 2 | Vestibular Schwannoma | Non-vestibular Schwannoma

United States
Children's Hospital Medical Center, Cincinnati
AstraZeneca

Active, not recruiting

Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors (SEL-TH-1601)

Glioma | Ependymoma | Meningioma | Neurofibromatosis 2 | Vestibular Schwannoma

United States
National Cancer Institute (NCI)

Completed

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Neurofibromatosis Type 1 | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Visual Pathway Glioma

United States
Apurano Pharmaceuticals GmbH

Recruiting

Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis

Stroke | Pain | Multiple Sclerosis | Chronic Pain | Traumatic Brain Injury | Neuropathic Pain | Pain, Chronic | Chronic Pain Syndrome | Paraplegia | Phantom Pain | Pain Syndrome | Central Neuropathic Pain | Phantom Limb Syndrome With Pain

Germany
University Hospital Inselspital, Berne

Recruiting

Prognosis of Cerebral Small Vessel Disease - a Prospective Cohort Study (PRO-SVD)

Cerebral Amyloid Angiopathy | Cadasil | Small Vessel Cerebrovascular Disease | CAA - Cerebral Amyloid Angiopathy

Switzerland
Totus Medicines

Recruiting

A Study to Evaluate the Safety and Tolerability of TOS-358 in Adults With Select Solid Tumors

Cervical Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Squamous Cell Carcinoma of Head and Neck | Endometrial Cancer | Non-small Cell Lung Cancer | Urothelial Carcinoma | HER2-negative Breast Cancer

United States
The Cleveland Clinic

Recruiting

Vascular Lab Resource (VLR) Biorepository

Cardiovascular Diseases | Lymphedema | Thrombosis | Vasculitis | Peripheral Artery Disease | Metabolic Disease | Lipedema | Thoracic Outlet Syndrome | Vasospasm | Venous Disease | Fibromuscular Dysplasia | May-Thurner Syndrome | Carotid Disease | Aneurysmal Disease | Non-Atherosclerotic Chronic Arterial Occlusive Disease and other conditions

United States
University of Birmingham
IMPACT (funded by NHS Blood & Transplant, Anthony Nolan and Leukaemia UK)

Recruiting

Methods of T Cell Depletion Trial (MoTD) (MoTD)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Non Hodgkin Lymphoma | Chronic Myelogenous Leukemia

United Kingdom
Hjalmar Bouma

Recruiting

Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine (Acutelines)

Pneumonia | Sepsis | Shock | Hemorrhage | Emergencies | Thrombosis | Frailty | Syncope | Urinary Tract Infections | Acute Kidney Injury | Acute Disease | Pulmonary Embolism | Dyspnea | Anaphylaxis | Polypharmacy | Complication of Treatment | Electrolyte Disturbance | Skin Infection | Intoxication by Drug

Netherlands
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Registry of Older Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Cognitive/Functional Effects | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Leigh R. Hochberg, MD, PhD.
National Institute of Neurological Disorders and Stroke (NINDS); US Department... and other collaborators

Recruiting

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia (BrainGate2)

Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Cord Injuries | Tetraplegia | Brain Stem Infarctions | Locked in Syndrome

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Natural Killer Cells and Bortezomib to Treat Cancer

Multiple Myeloma | Chronic Myeloid Leukemia (CML) | Pancreatic Ca | Colon/Rectal Ca | Carcinoma, Non-Small -Cell Lung

United States

Clinical Trials on Health Information Technology

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