Clinical Trials on Heart-Assist Devices in South Africa

Total 2728 results

Armaron Bio Pty Ltd

Unknown

NP202 for Treatment of Post -STEMI Left Ventricular Systolic Dysfunction

ST Elevation Myocardial Infarction

Australia
BioMarin Pharmaceutical

Recruiting

Safety, Tolerability, and Efficacy Study of Valoctocogene Roxaparvovec in Hemophilia A With Active or Prior Inhibitors (GENEr8-INH)

Hemophilia A With Inhibitor | Hemophilia A With Anti Factor VIII

United States, United Kingdom, Taiwan, Israel, Korea, Republic of, South Africa, Brazil, Italy, Germany
University of Adelaide

Unknown

Effects of Renal Sympathetic Denervation on the Cardiac and Renal Functions in Patients With Drug-resistant Hypertension Through MRI Evaluation (RDN)

Uncontrolled Hypertension

Australia
Medtronic Cardiovascular
Medtronic Australasia

Completed

CoreValve® System Australia/New Zealand Clinical Study

Aortic Valve Stenosis

New Zealand, Australia
Stanford University
Brigham and Women's Hospital; Allegheny Singer Research Institute (also known... and other collaborators

Completed

Low Fluoroscopy Afib Ablation Registry

Atrial Fibrillation

United States
Cala Health, Inc.

Not yet recruiting

Peripheral Nerve Stimulation Therapy for Atrial Fibrillation

Atrial Fibrillation

United States
Cardiac Dimensions Pty Ltd

Terminated

An Initial Evaluation of the Carillon Mitral Contour System for Treatment of Atrial Function Mitral Regurgitation (AFIRE)

Atrial Fibrillation | Functional Mitral Regurgitation | Atrial Functional Mitral Regurgitation

Australia, Greece
Mast Therapeutics, Inc.

Terminated

Evaluation of Vepoloxamer in Chronic Heart Failure

Chronic Heart Failure

United States, Australia
Synvista Therapeutics, Inc

Terminated

Safety & Efficacy of ALT-711 (Alagebrium) in Chronic Heart Failure (BENEFICIAL)

Chronic Heart Failure

United States
The Medicines Company

Completed

A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX) (CHAMPION)

Atherosclerosis | Acute Coronary Syndrome | Percutaneous Coronary Intervention

United States
Resverlogix Corp
South Australian Health and Medical Research Institute

Terminated

Characterization of Multi-dose RVX000222 in Combination With Statin Treatment in Dyslipidemia

Coronary Artery Disease | Dyslipidemia

Australia
Nigel E. Drury

Unknown

Pharmacology of Immunosuppressants Following Heart Transplantation

Heart Transplantation

Australia, United Kingdom
University of New England, Australia

Completed

Isometric Handgrip Exercise for Blood Pressure Management

Hypertension

Australia
GlaxoSmithKline

Completed

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Amlodipine and Losartan in Health Volunteers

Hypertension

Australia
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Dicrotic Notch and Hypotension at Caesarean Under Spinal Anaesthesia (DINOCS)

Hypotension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Terminated

The Efficacy of Spironolactone in Patients With Resistant Hypertension

Hypertension

United Kingdom
University of New England, Australia

Completed

Isometric Handgrip Exercise for Blood Pressure Management

Hypertension

Australia
GlaxoSmithKline

Completed

A Fixed Dose Combination Amlodipine + Enalapril Bioavailability Study

Hypertension

Australia
Alcon Research

Completed

IOP-Lowering Efficacy of Brinzolamide 1.0% Added to Travoprost 0.004%/Timolol 0.5% Fixed Combination as Adjunctive Therapy

Glaucoma

Australia
South Western Ambulance Service NHS Foundation...
Royal Devon and Exeter NHS Foundation Trust; Academic Health Science Centres

Completed

Evaluation of the Valsalva Assist Device to Treat SVT (EVADE)

Emergencies | SVT | Vagal Bradycardia

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

The Effect of Exercise on Peripheral Blood Gene Expression in Angina

Angina Pectoris

United Kingdom
Novartis Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Amlodipine in Essential Hypertension

Hypertension

Sweden, United States, Peru, Russian Federation, Romania, Mexico, Panama, Spain, Denmark, Italy, Greece, South Africa, Canada, Argentina, Australia, Colombia, Finland, Taiwan
Attikon Hospital

Unknown

Non-invasive Stroke Volume-based ﬂuid Management in Elderly Patients Undergoing Hip Fracture Surgery Under Spinal Anaesthesia (AttikonHSV)

Fluid Management | Haemodynamic Instability

Greece
Rapid City Regional Hospital, Inc
AstraZeneca

Completed

Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients

Coronary Artery Disease

United States
Wentworth Area Health Services
Abbott

Unknown

Levosimendan Versus Dobutamine in Shock Patients

Septic Shock | Cardiogenic Shock

Australia
Medical University of South Carolina
Shockwave Medical, Inc.

Terminated

Shockwave Assisted Large Bore Access

Vascular Diseases

United States
Medical University of South Carolina
MUSC Center for Biomedical Research Excellence (COBRE) in Stroke Recovery

Completed

Gait Mate: Examining Neural Networks Engaged During Lower Extremity Movement in the MRI

Stroke | Motor Activity

United States
Stereotaxis
Medtronic

Terminated

HEAL-HF: A Cardiac Resynchronization Therapy (CRT) Outcomes Study

Heart Failure, Congestive

United States, Canada, Italy
Bristol-Myers Squibb
Cardioxyl Pharmaceuticals, Inc

Completed

A Dose-Defining Study of CXL-1020 in Patients With Systolic Heart Failure

Heart Failure

United States
Tenaxis Medical, Inc.

Completed

ArterX Surgical Sealant, A Randomized Prospective Multicenter Trial (StEPS)

Vascular Disease

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Withdrawn

Study of the Vascular Response to Percutaneous Coronary Intervention in Patients With Non-ST-elevation Acute Coronary Syndromes Using Intravascular Blood Sampling (IN HEART)

Non ST Segment Elevation Acute Coronary Syndrome

United Kingdom
Monash University
Curtin University; Flinders University; Ambulance Victoria; SA Ambulance Service; St John Ambulance Australia (Western Australia)

Unknown

Reduction of Oxygen After Cardiac Arrest (EXACT)

Out-of-Hospital Cardiac Arrest

Australia
TaiGen Biotechnology Co., Ltd.

Completed

Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections

Diabetic Foot Infections

Taiwan, United States, South Africa, Thailand
Sydney South West Area Health Service

Unknown

IVUS Controlled Stenting

Coronary Angioplasty and Stenting | Single de Novo Coronary Artery Stenoses

Australia
US Department of Veterans Affairs

Completed

Veteran Preference For Group Visits and Its Effect on Hypertension Outcomes

Hypertension | Blood Pressure

United States
The George Institute
National Health and Medical Research Council, Australia; New South Wales Health and other collaborators

Completed

Changing Population Salt Consumption in Lithgow, Australia

Hypertension | Cardiovascular Disease | Blood Pressure

Australia
Regado Biosciences, Inc.
Icahn School of Medicine at Mount Sinai; The Cleveland Clinic; Parexel; Duke Clinical... and other collaborators

Terminated

A Study To Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI (Regulate)

Coronary Artery Disease

United States
Boston Scientific Corporation

Completed

ACURATE Prime XL Human Feasibility Study

Aortic Stenosis

Australia
Cadrock Pty. Ltd.
Centre for Digestive Diseases, Australia

Terminated

Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease (ACAC-CHD)

Coronary Heart Disease | Chlamydophila Pneumoniae Infections

Australia
AMAG Pharmaceuticals, Inc.

Terminated

Study of the Efficacy and Safety of AMAG-423 (Digoxin Immune Fab) in Antepartum Subjects With Severe Preeclampsia

Severe Preeclampsia

United States, Poland, South Africa
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

The Pleth Variability Index and Hypotension at Caesarean Under Spinal.

Caesarean Section

United Kingdom
Eli Lilly and Company

Completed

Hyperglycemia and Cardiovascular Outcomes With Type 2 Diabetes (IONM)

Diabetes Mellitus, Type 2 | Acute Myocardial Infarction

Canada, Croatia, Czech Republic, Germany, Hungary, India, Israel, Lebanon, Poland, Romania, Russian Federation, Slovakia, Slovenia, South Africa, Spain, Turkey, United Kingdom
Flinders University
Flinders Medical Centre; Lyell McEwin Hospital

Recruiting

Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)

Myocardial Injury | Myocarditis | Cardiotoxicity | Immune Checkpoint Inhibitors

Australia
National Center for Research Resources (NCRR)

Completed

Vitamin D Metabolism and the Williams Syndrome

Williams Syndrome

United States
Ural State Medical University
Ural Institute of Cardiology; De Haar Research Foundation

Completed

Paricalcitol Versus Calcitriol for the Management of Renocardiac Syndrome in Renal Transplant Patients

Cardiorenal Syndrome | Chronic Allograft Nephropathy

Netherlands, Russian Federation
Medical University of South Carolina

Active, not recruiting

Patient Centered Health Technology Medication Adherence Program for African American Hypertensives (SMASH)

Hypertension | Medication Non-Adherence

United States
Medical University of South Carolina

Completed

Feasibility Study of Cryotherapy for Chronic Venous Disorders (Cryo)

Venous Insufficiency

United States
Abbott Medical Devices

Completed

Cardiac Resynchronization Therapy Defibrillator Based Impedance Monitoring Study

Heart Failure

United States
Angiodynamics, Inc.

Completed

Initial Experience With the AngioVac Venous Drainage Cannula

Heart Disease

United States
Corvia Medical

Active, not recruiting

REDUCE LAP-HFREF TRIAL

Heart Failure

Australia, United States, Czechia

Clinical Trials on Heart-Assist Devices in South Africa

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