Clinical Trials on Hepatic Enzymes in Finland

Total 42 results

University of Helsinki
GE Healthcare

Completed

Neuromonitoring of Hepatic Encephalopathy

Liver Failure, Acute | Hepatic Encephalopathy

Finland
Helsinki University Central Hospital
University Hospital Inselspital, Berne

Completed

Targeted Tissue Perfusion Versus Macrocirculatory-guided Standard Care in Patients With Septic Shock (TARTARE-2S)

Critical Illness | Shock; Septic

Finland, Switzerland
Helsinki University Central Hospital

Completed

Assessment of Fluid Responsiveness by Elevation of PEEP in Patients With Septic Shock

Septic Shock

Finland
Rigshospitalet, Denmark

Completed

A Study of the Effect of Plasmaexchange in Patients With Acute Liver Failure

Acute Liver Failure

Denmark, Finland, United Kingdom
Turku University Hospital
University of Turku

Recruiting

Safety and Efficacy of HA380 Hemoadsorption in Patients With Septic Shock (HEMOX-HDF)

Septic Shock | Acute Kidney Injury

Finland
Herlev Hospital

Completed

Lactic Acid in the Rectum and Life-Threatening Infection

Septic Shock

Denmark, Finland
Alteco Medical AB
Uppsala University; TFS Trial Form Support

Terminated

ASSET - a Double-Blind, Randomized Placebo-Controlled Clinical Investigation With Alteco® LPS Adsorber (ASSET)

Septic Shock

Finland, Norway, Sweden
University Hospital, Linkoeping

Recruiting

May the Risk of PHLF be Predicted With Preoperative Liver Gadoxetate MRI (MR-Predict)

MRI | Liver Resection | Liver Failure as A Complication of Care

Sweden, Norway, Denmark, Finland
Helsinki University Central Hospital
University of Helsinki; Academy of Finland

Completed

Donor Simvastatin Treatment in Organ Transplantation (SIMVA)

Liver Failure | Heart Failure | Respiratory Failure | Kidney Failure | Transplantation

Finland
Anders Perner

Completed

Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care (CLASSIC)

Sepsis | Septic Shock

Denmark, Finland
Tampere University Hospital
Tampere University; Tampere University of Technology

Completed

Suitability of Unobtrusive Bed Monitoring and Wrist-worn Heart Rate Monitor for Patient Monitoring (BedMon)

Hemorrhage | Septic Shock | Sleep | Arrhythmia | Consciousness, Loss of

Finland
Rhode Island Hospital

Completed

Restrictive Intravenous Fluids Trial in Sepsis (RIFTS)

Septic Shock | Severe Sepsis

United States
Alnylam Pharmaceuticals

Completed

EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)

Acute Hepatic Porphyria

United States, Belgium, Bulgaria, France, Italy, Mexico, Spain, Taiwan, United Kingdom, Netherlands, Korea, Republic of, Switzerland, Czechia, Poland, Finland, Australia, Germany, Israel, Norway, South Africa
Shire
PPD

Completed

Blinded Safety & Efficacy Placebo Controlled Study of Icatibant for Angiotensin Converting Enzyme Inhibitor Induced Angioedema

Angiotensin Converting Enzyme Inhibitor Induced Angioedema

United States, Canada, United Kingdom, Israel
Clinuvel Pharmaceuticals Limited

Completed

Phase III Confirmatory Study in Erythropoietic Protoporphyria (EPP)

Erythropoietic Protoporphyria

Netherlands, Finland, France, Germany, Ireland, United Kingdom
Scandinavian Critical Care Trials Group
Rigshospitalet, Denmark; University of Copenhagen; Copenhagen Trial Unit, Center...

Completed

Transfusion-requirements in Septic Shock Trial (TRISS)

Septic Shock

Sweden, Norway, Finland, Denmark
Alnylam Pharmaceuticals

Completed

ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)

Acute Hepatic Porphyria | Acute Intermittent Porphyria | Porphyria, Acute Intermittent | Acute Porphyria | Hereditary Coproporphyria (HCP) | Variegate Porphyria (VP) | ALA Dehydratase Deficient Porphyria (ADP)

United States, Spain, United Kingdom, Korea, Republic of, Australia, Bulgaria, Canada, Denmark, Finland, France, Germany, Italy, Japan, Mexico, Netherlands, Poland, Sweden, Taiwan
Anders Perner
Rigshospitalet, Denmark; University of Copenhagen; B. Braun Melsungen AG; Copenhagen...

Completed

Scandinavian Starch for Severe Sepsis/Septic Shock Trial (6S)

Septic Shock | Severe Sepsis

Denmark, Norway, Finland, Iceland
Boehringer Ingelheim

Completed

A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic Functions

Hepatic Insufficiency | HIV Infections

France, United States, Spain
Rhode Island Hospital

Recruiting

Assessment for Implementation Methods in Sepsis (AIMS)

Septic Shock | Sepsis Severe

United States
The Miriam Hospital

Recruiting

De-resuscitation Informed by Ultrasound for Patients With Sepsis (DRI-US)

Sepsis | Septic Shock | Sepsis, Severe | Volume Overload

United States
Bausch Health Americas, Inc.

Active, not recruiting

Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis (RED-C-3132)

Hepatic Encephalopathy

United States, Australia, Belgium, Bulgaria, Canada, France, Germany, Hungary, India, Italy, Korea, Republic of, Mongolia, New Zealand, Poland, Puerto Rico, Spain, United Kingdom
AstraZeneca

Completed

A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer

Gastrointestinal Hemorrhage

Sweden, Russian Federation, South Africa, Spain, Turkey, United Kingdom, Germany, Romania, Finland, Norway, Hong Kong, Austria, Denmark, Netherlands, Greece, France
AstraZeneca

Completed

A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock

Septic Shock | Severe Sepsis

Czech Republic, France, Spain, Finland, Canada, Australia, Belgium
Eli Lilly and Company

Completed

Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock

Sepsis

Italy, United Kingdom, United States, Germany, Spain, Belgium, France, Australia, Czech Republic, Netherlands, Canada, Mexico, New Zealand, Finland, Portugal, Brazil, India, Switzerland
Inotrem

Active, not recruiting

Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock (ASTONISH)

Shock, Septic

Belgium, France, Spain, Denmark, Finland, Ireland
AstraZeneca

Completed

Esomeprazole (NEXIUM) vs. Surgery (LOTUS)

Gastroesophageal Reflux

Italy, Sweden, Germany, Denmark, Finland, Norway, Netherlands, Austria, Belgium, United Kingdom, France, Iceland
Children's Hospital of Philadelphia
M.D. Anderson Cancer Center; The Hospital for Sick Children; Eunice Kennedy Shriver... and other collaborators

Recruiting

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (PRoMPT BOLUS)

Shock | Septic

United States
Takeda

Completed

Comparison of Dexlansoprazole MR to Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, Canada, Peru, Russian Federation, Australia, New Zealand, Czech Republic, Slovakia, South Africa, Latvia, Lithuania, Colombia, Germany
AstraZeneca

Completed

NEXIUM® in the Treatment of Moderate and Severe Erosive Esophagitis

Gastroesophageal Reflux Disease | Erosive Esophagitis | Reflux Esophagitis

United States
Brown University

Recruiting

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Arthritis | Chronic Pain | Chronic Low-back Pain | Irritable Bowel Syndrome | Fibromyalgia | Acute Pain | Trauma, Multiple | Neuropathic Pain | Temporomandibular Joint Disorders | Post Operative Pain | Chronic Pain Syndrome | Chronic Shoulder Pain | Painful Diabetic Neuropathy | Chronic Migraine | Painful Bladder Syndrome and other conditions

United States
Eisai Inc.

Completed

Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Moderate Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

United States
Shire

Completed

Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Czechia, Germany, Latvia, Poland, Romania
Pfizer

Completed

A Study To Compare Pregabalin/PF-00489791 Combination Versus Pregabalin Alone In Post-Herpetic Neuralgia

Postherpetic Neuralgia

United States
Eisai Inc.

Completed

Dose-Tolerability Titration Study to Evaluate The Efficacy And Safety Of Perampanel (E2007) In Patients With Post-Herpetic Neuralgia (PHN)

Neuralgia

United States, Canada
Ironwood Pharmaceuticals, Inc.

Completed

Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Gastroesophageal Reflux Disease (GERD)

United States, Canada
Eisai Inc.

Completed

Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroesophageal Reflux Disease (sGERD)

United States
Takeda

Completed

Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Heartburn

Gastroesophageal Reflux Disease

United States
AstraZeneca

Completed

Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on Low Dose Acetylsalicylic Acid (LDA) (Oberon)

Gastric Ulcer | Duodenal Ulcer

United States, Bulgaria, Czech Republic, Korea, Republic of, Russian Federation, South Africa, Philippines, Poland, Romania, Finland, Norway, Canada, Mexico, Argentina, Australia, Germany, Portugal, Slovakia, Thailand, Indonesia
Celldex Therapeutics
Merck Sharp & Dohme LLC

Completed

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Melanoma | Follicular Lymphoma | Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Fallopian Tube Cancer | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | ... and other conditions

United States
Rigshospitalet, Denmark
University College, London

Enrolling by invitation

EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV (EuroSIDA)

End Stage Liver Disease | Cardiovascular Diseases | Fractures, Bone | Diabetes Mellitus | Renal Insufficiency | Hepatitis B | Hepatitis C | Kidney Failure, Chronic | Proteinuria | HIV | Coinfection | Acidosis, Lactic | AIDS

Spain, Switzerland, Germany, United Kingdom, Austria, Sweden, Finland, Israel, Denmark, France, Italy, Iceland, Belgium, Slovakia, Norway, Lithuania, Portugal, Poland, Croatia, Czechia, Greece, Hungary, Luxembourg, Argentina, Belarus, Bosnia... and more

Clinical Trials on Hepatic Enzymes in Finland

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