Clinical Trials on Hyper-IgM+Immunodeficiency+Syndrome%2C+Type+1

Total 582 results

Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

Sleep Apnea in Type 1 Diabetes (DIASOM)

Type 1 Diabetes, Sleep Apnea Syndrome

France
Hospices Civils de Lyon

Recruiting

Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1) (MESO-SDRC)

Neuropathic Pain | Complex Regional Pain Syndrome Type 1

France
Novartis Pharmaceuticals

Completed

Canakinumab in Patients With Active Hyper-IgD Syndrome

Mevalonate Kinase Deficiency

Spain
Montefiore Medical Center
National Cancer Institute (NCI); University of Rwanda; Rwanda Military Hospital

Recruiting

HPV Vaccine Effectiveness Study in Rwandan Women Living With HIV

Cervical Cancer | Human Immunodeficiency Virus | HPV-Related Carcinoma | Human Papilloma Virus

Rwanda
National Human Genome Research Institute (NHGRI)

Completed

Twins Study of Gene Therapy for HIV Infection

Acquired Immunodeficiency Syndrome | HIV Infection | Kaposi's Sarcoma

United States
Medical University Innsbruck

Unknown

Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 Mutation (CMMRD in NF1)

Neurofibromatosis Type 1
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Completed

Effect of Methamphetamine on Residual Latent HIV Disease Study (EMRLHD)

Methamphetamine-dependence | HIV-1-infection

United States
National Institute of Cancerología
Instituto Nacional de Enfermedades Respiratorias

Completed

Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.

Kaposi Sarcoma | Human Immunodeficiency Virus | Immune Reconstitution Syndrome

Mexico
The Eye Center and The Eye Foundation for Research...

Completed

Tyrosine Hydroxylase Antibody Levels in Autoimmune Polyglandular Syndrome Type 1 Associated Keratitis

Autoimmune Polyglandular Syndrome Type I | Autoimmune Keratitis
Ferring Pharmaceuticals

Completed

A Study of Terlipressin in Patients With Hepatorenal Syndrome Type 1 (HRS)

Hepatorenal Syndrome Type 1

Japan
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Orpha Labs

Completed

Study of ORL-1F (L-fucose) in Patients With Leukocyte Adhesion Deficiency Type II

Leukocyte Adhesion Deficiency, Type II
Medical University of South Carolina
National Institute of Mental Health (NIMH); Muhimbili University of Health...

Completed

Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care In Kisarawe, Tanzania

Hypertension | Diabetes Mellitus, Type 2 | Human Immunodeficiency Virus

Tanzania
University Hospital, Grenoble
ResMed; Société francophone de pneumologie de langue francaise

Completed

Effect of Sleep Apnea Treatment on Type 1 Diabetes (DIADEME)

Type 1 Diabetes | Sleep Apnea Syndrome

France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Retrovirus Epidemiology Donor Study-II (REDS-II)

HIV Infections | Acquired Immunodeficiency Syndrome | Retroviridae Infections | Hepatitis B | Hepatitis, Viral, Human | Blood Transfusion | HIV-1 | Blood Donors | Hepacivirus | HIV-2 | HTLV-I | HTLV-II | West Nile Virus
Postgraduate Institute of Medical Education and...

Completed

Terlipressin Infusion Alone Vs Terlipressin With Noradrenaline Infusion In The Treatment of Hepatorenal Syndrome Type 1

Type 1 HEPATO RENAL SYNDROME(HRS)

India
University of Utah
University of British Columbia; Children's Hospital Medical Center, Cincinnati and other collaborators

Terminated

Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1) (VitDBoneNF1)

Neurofibromatosis Type 1 (NF1)

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myelodysplastic Syndrome With Excess Blasts | Chronic Myelomonocytic Leukemia-1 | Chronic Myelomonocytic Leukemia-2 | Myelodysplastic Syndrome With Excess Blasts-1 | Myelodysplastic Syndrome/Acute Myeloid Leukemia

Canada, United States
University of Padova

Unknown

Terlipressin Given As I.V. Boluses Versus Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome

Cirrhosis | Type 1 Hepatorenal Syndrome

Italy
Brown University
The Miriam Hospital; National Institute of General Medical Sciences (NIGMS)

Recruiting

Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection

Alcohol Drinking | HIV-1-infection

United States
University of Alabama at Birmingham

Completed

MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1 (MEK Inhibitor)

Neurofibromatosis Type 1 and Growing or Symptomatic, Inoperable PN

United States
Freeman-Sheldon Research Group, Inc.

Terminated

Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome (STOP-FSS)

Craniofacial Abnormalities | Arthrogryposis | Freeman-Sheldon Syndrome | Arthrogryposis Distal Type 2A | Whistling Face Syndrome | Craniocarpotarsal Dysplasia | Craniocarpotarsal Dystrophy | Freeman-Sheldon Syndrome Variant | Sheldon-Hall Syndrome | Arthrogryposis Distal Type 2B | Gordon Syndrome | Arthrogryposis... and other conditions

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Safety and Efficacy Study of Human T Lymphoid Progenitor (HTLP) Injection After Partially HLA Compatible Allogeneic Hematopoietic Stem Cell Transplantation in SCID Patients (HTLP Necker)

Pediatric Patients | Any Type of Severe Combined Immunodeficiency (SCID) | Partial HLA Incompatible Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

France
The University of Texas Health Science Center at...
National Heart, Lung, and Blood Institute (NHLBI)

Completed

KSHV Infection in Blood Donors From Texas

HIV Infections | Acquired Immunodeficiency Syndrome | Sarcoma, Kaposi | Blood Transfusion | Blood Donors | Herpesvirus, Kaposi Sarcoma-Associated
Merck Sharp & Dohme LLC

Completed

Study of Sotatercept for the Treatment of Anemia in low-or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) or Non-proliferative Chronic Myelomonocytic Leukemia (CMML)

Myelodysplastic Syndromes | Anemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndromes (MDS) | Chronic Myelomonocytic Leukemia (CMML) | Low to Intermediate-1 MDS

United States, France
University of British Columbia

Recruiting

A Study of Reduced Dosing of the Nonavalent HPV Vaccine in Women Living With HIV (NOVA-HIV)

Human Immunodeficiency Virus | HPV | Human Papilloma Virus

Canada
Vitaflo International, Ltd

Withdrawn

Evaluation of Krio in Children and Adults With Epilepsy (Krio)

Epilepsy | Glucose Transporter Type 1 Deficiency Syndrome | Ketogenic Dieting
National Cancer Institute (NCI)

Completed

A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents, and Young Adults

Adolescent | Human Immunodeficiency Virus | Papillomavirus Vaccines | Human Papillomavirus- 6, 11, 16, 18

United States
SpringWorks Therapeutics, Inc.

Active, not recruiting

MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas (ReNeu)

Plexiform Neurofibroma | Neurofibromatosis Type 1 (NF1)

United States
Fondazione Telethon

Unknown

Natural History Study in Subjects With Usher Syndrome

Usher Syndrome, Type 1B

Italy, Netherlands, Spain
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)

Plexiform Neurofibroma Associated With Neurofibromatosis Type 1

Israel
Hospices Civils de Lyon

Unknown

Rhythmic Risk of Type 1 Brugada Syndrome and Pulmonary Infundibulum Mapping (SB-CARTO)

Brugada Syndrome Type 1

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Withdrawn

HIV-Resistant Gene Modified Stem Cells and Chemotherapy in Treating Patients With Lymphoma With HIV Infection

Stage III Adult Hodgkin Lymphoma | Stage IV Adult Hodgkin Lymphoma | Human Immunodeficiency Virus 1 Positive | Stage I Adult Hodgkin Lymphoma | Stage II Adult Hodgkin Lymphoma | Stage I Adult Non-Hodgkin Lymphoma | Stage II Adult Non-Hodgkin Lymphoma | Stage III Adult Non-Hodgkin Lymphoma | Stage IV...

United States
University of California, Irvine
Doris Duke Charitable Foundation

Withdrawn

The Genetics of Diabetes in Southern California Chinese Americans

Metabolic Syndrome | Type 1 Diabetes | Type 2 Diabetes

United States
Pharvaris Netherlands B.V.

Active, not recruiting

Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (HAE CHAPTER-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Poland, Germany, Austria, Bulgaria, Canada, Ireland, Italy, United Kingdom
National Cancer Institute (NCI)

Completed

Clinical, Laboratory and Epidemiologic Pilot Studies of Individuals at High Risk for Viral-Associated Cancers

HIV Infections | Acquired Immunodeficiency Syndrome | Lymphoma | Leukemia | Kaposi's Sarcoma | Tumor Virus Infection

United States
Dufresne, Craig, MD, PC

Recruiting

Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome (FINDFSS)

Freeman-Sheldon Syndrome | Whistling Face Syndrome | Freeman-Sheldon Syndrome Variant | Sheldon-Hall Syndrome | Gordon Syndrome | Arthrogryposis Distal Type 3 | Arthrogryposis Distal Type 1 | Freeman-Burian Syndrome

United States
Pharvaris Netherlands B.V.

Completed

Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

Bulgaria, United States, Spain, Israel, Germany, Canada, Czechia, France, Hungary, Italy, Netherlands, Poland, United Kingdom
AstraZeneca

Completed

A Study to Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants

Healthy Participants | Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)

United States
Joslin Diabetes Center
ImmusanT, Inc.

Completed

Gluten Immunity and Islet Autoimmunity in Type-1 Diabetes

Type 1 Diabetes | Celiac Disease

United States
Pacific Northwest Research Institute
University of Exeter

Enrolling by invitation

Combined Antibody Screening for Celiac and Diabetes Evaluation (CASCADE)

Type 1 Diabetes | Celiac Disease

United States
TC Erciyes University

Recruiting

The Effect of Exercise on Metabolic Parameters, Anthropometric Measurement Values and Quality of Life

Type1diabetes | Metabolic Syndrome | Nursing Caries

Turkey
Reata, a wholly owned subsidiary of Biogen

Completed

A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX (PHOENIX)

Focal Segmental Glomerulosclerosis | IgA Nephropathy | Autosomal Dominant Polycystic Kidney | CKD Associated With Type 1 Diabetes

United States
Centre Hospitalier Universitaire Dijon

Unknown

Type 1 Multiple Endocrine Neoplasia Cohort Study (MEN1-GTEcohort)

Type 1-Multiple Endocrine Neoplasia Syndrome

France
Mozart Therapeutics Australia Pty Ltd

Not yet recruiting

Safety, Pharmacokinetics, and Pharmacodynamics of MTX-101 in Healthy Adults and Patients

Type 1 Diabetes | Celiac Disease | Healthy Volunteers

Australia
University Hospital, Grenoble
ResMed; VitalAire

Completed

Prevalence of Obstructive Sleep Apnea Syndrome in Type 1 Diabetic Patients Treated With Insulin Pump (At1Home) (AT1Home)

Type 1 Diabetes

France
Louisiana State University Health Sciences Center...
Merck Sharp & Dohme LLC

Recruiting

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV (AGO-Gard)

Cervical Intraepithelial Neoplasia | Human Immunodeficiency Virus | Anal Intraepithelial Neoplasia | Papillomavirus Infection | Papillomavirus Vaccines | Serology | Oral Cavity Infection

United States
Fred Hutchinson Cancer Center
University of Washington; Seattle Children's Hospital

Active, not recruiting

Blood Samples to Identify Biomarkers of Busulfan

Lymphoma | Leukemia | Multiple Myeloma | Myelodysplastic Syndrome | Immunodeficiency

United States
National Cancer Institute (NCI)

Recruiting

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Neurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome

United States
SpringWorks Therapeutics, Inc.

Available

Individual Patient Compassionate Use of Mirdametinib

Neurofibromatosis Type 1-Associated Plexiform Neurofibromas | Histiocytic Neoplasm | Other MAP-K Pathway Driven Diseases

Clinical Trials on Hyper-IgM+Immunodeficiency+Syndrome%2C+Type+1

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CROs by country

CROs in Cyprus

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