Clinical Trials on Hypercholesterolemia in Ireland

Total 36 results

AstraZeneca

Completed

A Study Measuring Effects on Intima Media Thickness: An Evaluation of Rosuvastatin 40 mg (METEOR)

Hypercholesteremia

United States, France, Norway, Netherlands, Belgium, Germany, Finland, Czech Republic
PepsiCo Global R&D

Completed

The Effect of Oats Containing 1.4g Beta Glucan on Fecal Bacterial Population(s) and Plasma Cholesterol in Healthy Adults With Elevated Cholesterol Levels

Microbiome | Plasma Cholesterol | Prebiotic

Ireland
Sunnybrook Health Sciences Centre
Merck Frosst Canada Ltd.; Schering-Plough

Terminated

INdians Followed for INtensive Lipid Lowering Treatment and Its safetY (INFINITY)

Hypercholesterolemia

Canada
Brown University
Johns Hopkins University; National Institute on Aging (NIA); Tufts Medical Center and other collaborators

Completed

Pharmacy Home Adherence Reporting and Monitoring Outcomes Study (PHARxMOS)

Hypertension | Diabetes | Hypercholesterolemia

United States
Novartis Pharmaceuticals

Completed

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C (ORION-8)

Elevated Cholesterol | Homozygous Familial Hypercholesterolemia | Heterozygous Familial Hypercholesterolemia | ASCVD

United States, Canada, Czechia, Denmark, Germany, Hungary, Netherlands, Poland, South Africa, Spain, Sweden, Ukraine, United Kingdom
Pfizer

Completed

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia (SPIRE-FH)

Heterozygous Familial Hypercholesterolemia

Canada, Netherlands, United Kingdom, United States, Spain, Poland, Finland, Norway, South Africa, Italy, Bulgaria
Bristol-Myers Squibb

Completed

Safety Study of BMS-770767 in Subjects With Hypercholesterolemia

Dyslipidemia

Canada, Australia, United States
Memorial Hospital of Rhode Island
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Translating ATP III Cholesterol Management Guidelines Into Primary Care Practice

Coronary Disease | Hypercholesterolemia | Primary Health Care | Management, Risk

United States
Pfizer

Completed

A Multiple Dose Study Of PF-04950615 (RN316) In Subjects On Maximum Doses Of Statins

Dyslipidemia | Hypercholesterolemia

United States, Canada
Amgen

Completed

Open-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Hypercholesterolemia

Canada, Netherlands, Spain, Belgium, United States, Russian Federation, Czechia, Mexico, Korea, Republic of, Australia, United Kingdom, Argentina, Israel, France, Hungary, Germany, Greece, Poland, Switzerland, Italy, Brazil, Sweden, Norwa... and more
Pfizer

Completed

Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia

Hyperlipidemia | Hypercholesterolemia, Familial

Australia, Canada, United States, France, South Africa, Sweden, Norway, Denmark, Iceland
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE)

Hypercholesterolemia

United States, France, Italy, Israel, United Kingdom, Austria, Canada, Norway
Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (V-Mono)

Hypercholesterolemia

United States, Hungary, Mexico, Germany, Colombia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Canadians Achieve Cholesterol Targets Fast With Atorvastatin Stratified Titration (CANACTFAST)

Hypercholesterolemia

Canada
Pfizer

Completed

A Multiple Dose Study of PF-04950615 (RN316) in Subjects on High Doses of Statins

Dyslipidemia | Hypercholesterolemia

United States, Canada
Pfizer

Completed

Monthly And Twice Monthly Subcutaneous Dosing Of PF-04950615 (RN316) In Hypercholesterolemic Subjects On A Statin

Hypercholesterolemia

United States
Regeneron Pharmaceuticals

Completed

Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia

Hypercholesterolemia

United States, Spain, Australia, Netherlands, Japan, Jordan, Denmark, Israel, Sweden, South Africa, Canada, Austria, Czechia, France, Italy, New Zealand, Norway, Poland, Russian Federation, United Kingdom
Takeda

Completed

Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, Canada
Amgen

Completed

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound (GLAGOV)

Hypercholesterolemia

United States, Canada, Denmark, Germany, Italy, Netherlands, Spain, Sweden, Belgium, Taiwan, Russian Federation, France, Czechia, Mexico, Korea, Republic of, Australia, United Kingdom, Argentina, Israel, Hungary, South Africa, Greece and more
Takeda

Completed

Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, Canada
Takeda

Completed

Efficacy of Lapaquistat Acetate and Atorvastatin on Blood Cholesterol Levels in Subjects With Primary Hypercholesterolemia

Hypercholesterolemia

United States
Pfizer

Terminated

A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol (A5091031).

Dyslipidemia | Hypercholesterolemia | Hyperlipidemia

United States
Amgen

Completed

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study (DESCARTES)

Hypercholesterolemia

United States, Denmark, Belgium, Czechia, Austria, Australia, Canada, Hungary, South Africa
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)

Hypercholesterolemia

United States, France, Italy, Germany, Spain, Canada, United Kingdom, Australia, Mexico
Takeda

Terminated

Efficacy of Lapaquistat Acetate Co-Administered With Statins in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States
Pfizer

Completed

A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol.

Dyslipidemia | Hypercholesterolemia | Hyperlipidemia

United States
Regeneron Pharmaceuticals
Sanofi

Completed

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

Hypercholesterolemia

United States, Bulgaria, Chile, Estonia, Japan, Mexico, Russian Federation, South Africa, Ukraine
Regeneron Pharmaceuticals
Sanofi

Completed

Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)

Hypercholesterolemia

United States, France, Italy, Germany, Spain, Mexico, Canada, United Kingdom, Australia
Sanofi
Regeneron Pharmaceuticals

Completed

Long-term Safety and Tolerability of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY Long Term)

Hypercholesterolemia

Sweden, Germany, Russian Federation, Denmark, Israel, South Africa, Spain, Hungary, United States, Colombia, Czech Republic, Argentina, Belgium, Bulgaria, Canada, Chile, Finland, France, Italy, Mexico, Netherlands, Norway, Poland, Por... and more
Amgen

Completed

Open Label Study of Long Term Evaluation Against LDL-C Trial (OSLER)

Hypercholesterolemia

United States, Denmark, Finland, Czechia, Hungary, South Africa, Spain, Australia, Belgium, Canada, Netherlands, Germany, Sweden, Hong Kong, Japan, Singapore, United Kingdom, Norway
Esperion Therapeutics, Inc.
Medpace, Inc.

Completed

Evaluation of ETC-1002 in Participants With Hypercholesterolemia and Hypertension

Hypertension | Hypercholesterolemia

United States
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intolerant (CLEAR Serenity)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease | Statin Adverse Reaction

United States, Canada
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events (SANTORINI)

Cardiovascular Diseases | Dyslipidemia | Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Finland, Netherlands, Spain, Belgium, Sweden, Austria, United Kingdom, Switzerland, Denmark, France, Germany, Portugal, Italy, Ireland
The Medicines Company

Completed

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol (ORION-10)

Elevated Cholesterol | ASCVD

United States
Furiex Pharmaceuticals, Inc

Completed

Study of the Safety and Tolerability Associated With PPD10558 Versus Atorvastatin in Patients Previously Intolerant to Statins Due to Statin-associated Myalgia (SAM)

Myalgia | Hypercholesterolemia | Hyperlipidemia

United States
Amgen

Completed

Evaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemia (BANTING)

Type 2 Diabetes | Hypercholesterolemia | Mixed Dyslipidemia

United States, Italy, Belgium, Spain, Canada, Poland, Mexico

Clinical Trials on Hypercholesterolemia in Ireland

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