Clinical Trials on Infant Newborn in South Africa

Total 278 results

University of Stellenbosch
Stanford University

Completed

Transcutaneous Screening for Risk of Severe Hyperbilirubinemia in South African Newborns

Hyperbilirubinemia | Neonatal Jaundice

South Africa
Centers for Disease Control and Prevention
United States Agency for International Development (USAID); Bill and Melinda... and other collaborators

Unknown

Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

Sepsis | Infant, Newborn, Diseases | Puerperal Infection

South Africa
Charles G. Prober
Stanford University; Heidelberg University; University of Stellenbosch; University...

Completed

The Philani Mobile Video Intervention for Exclusive Breastfeeding (MOVIE) Study (MOVIE)

Exclusive Breastfeeding | Infant Feeding Practices

South Africa
University of Stellenbosch
Fogarty International Center of the National Institute of Health

Unknown

Neonatal Bacterial Colonization Study

Prematurity | Bloodstream Infection | Neonatal SEPSIS | Very Low Birth Weight Baby

South Africa
Abbott Nutrition

Completed

Growth and Tolerance of Young Infants Fed Infant Formulas

Infant Newborn

United States
Nestlé

Terminated

Effect of a Starter Formula With Synbiotics on Stool Microbiota in Infants After Normal or Caesarean Section Delivery

Healthy Full Term Infants

South Africa
Cardiff and Vale University Health Board
Cardiff University

Completed

Estimating Insertion Length of Umbilical Catheters in Newborn Infants

Infant, Newborn, Diseases

United Kingdom
University of Cape Town
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV (BifIID)

Vaccine Reaction | Hiv | Microbial Colonization | Infant Development

South Africa
University of KwaZulu
University of California, San Francisco; Centers for Disease Control and Prevention and other collaborators

Completed

Effectiveness of an HIV-adapted IMCI Training and Supervision Programme for Community Health Workers

Infant Feeding Practices | Prevention of Mother-to-child Transmission of HIV | Antenatal Health Care Utilization | Postnatal Health Care Utilization

South Africa
ByHeart
Paidion Research, Inc.

Completed

Evaluation of Growth, Safety, and Efficacy of an Infant Formula for Healthy Term Infants

Newborn | Infants

United States
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Mitigating Infectious Morbidity and Growth Deficits in HIV Exposed Uninfected infanTs With Human Milk Oligosaccharides (MIGH-T MO)

HIV | Breast Feeding | Infant Morbidity

South Africa
University of Athens
University of Thessaly

Completed

Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure (HFO-TGI-2)

Respiratory Distress Syndrome

Greece
Swiss Federal Institute of Technology
North-West University, South Africa

Completed

Establishing the Iodine Requirement in Infancy

Focus: Establish the Iodine Requirement During Infancy

Switzerland, South Africa
Novartis Vaccines
GlaxoSmithKline

Completed

Study to Identify Factors Influencing Access of Pregnant Women and Their Infants to Local Healthcare Systems

Pregnancy, Newborn Health

Dominican Republic, Mozambique, Panama, South Africa
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir (ORCHID)

Obesity | HIV | Maternal Obesity During Childbirth | Maternal Obesity Complicating Pregnancy | Obesity, Infant

South Africa
University of Athens

Completed

Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome

Respiratory Distress Syndrome, Adult

Greece
Draeger Medical Systems, Inc.

Unknown

Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW Neonates

Respiratory Distress Syndrome In Premature Infants

United States
Sonderborg Hospital
Aase and Ejnar Danielsens Foundation; The Augustinus Foundation, Denmark.; The...

Completed

Acupuncture for Pain Relief During Perineal Repair After Childbirth

Pain | Lacerations | Birth Injuries

Denmark
Drugs for Neglected Diseases
Universiteit Antwerpen; PENTA Foundation; St George's, University of London

Completed

NeoAMR Observational Study in Neonatal Sepsis

Neonatal SEPSIS

Bangladesh, Uganda, Thailand, South Africa, Italy, Greece, India, Brazil, China, Kenya, Vietnam
University of Athens
University of Thessaly

Terminated

High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS)

Acute Respiratory Distress Syndrome

Greece
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
Prisma Health-Midlands

Withdrawn

N-Acetyl-cysteine in Early Acute Respiratory Distress Syndrome (NARDS)

Acute Respiratory Distress Syndrome

United States
Cardiff and Vale University Health Board
Cardiff University

Recruiting

nSeP: Detecting Neonatal Sepsis by Immune-Metabolic Network Analysis (nSeP)

Sepsis

United Kingdom
University of Athens

Completed

Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO

Acute Respiratory Distress Syndrome | Acute Cor Pulmonale

Greece
South Shore Hospital
Q-Med Scandinavia, Inc.

Terminated

Minimally Invasive Closure of Umbilical Hernias (MIC)

Umbilical Hernia

United States
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Completed

IMPAACT P1106: Pharmacokinetic Characteristics of Antiretrovirals and Tuberculosis Medicines in Low Birth Weight Infants

HIV | Tuberculosis | Low-Birth-Weight Infant

South Africa
Mednax Center for Research, Education, Quality...

Completed

Registry for Severe ROP and Treatment on Visual Outcomes

Retinopathy of Prematurity

United States
University of Alberta

Completed

Acupuncture for Preterm Infants Requiring Eye-exam (MAGNIFIC-ROP)

Pain | Retinopathy of Prematurity | Acupuncture | Premature Infant

Canada, Australia, Malaysia
University of Athens
Academy of Athens

Completed

Clinical and Biological Markers in Acute Respiratory Failure

Acute Respiratory Distress Syndrome | Ventilator-Associated Pneumonia

Greece
Novartis Pharmaceuticals

Completed

Second Open Label Extension to Bridging Study CTBM100C2303

Pseudomonas Aeruginosa | Pulmonary Infections

Russian Federation, Romania, Estonia, Latvia, Lithuania, Bulgaria, South Africa
Anchora Medical

Recruiting

Laparoscopic Primary Umbilical Hernia Repair With Routine Defect Closure Using Su2ura Approximation Device

Primary Umbilical Hernia

Israel, Slovenia
University of Athens

Recruiting

Cerebral Autoregulation and COVID-19 (CA-COVID)

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

Greece
Spark Biomedical, Inc.
Medical University of South Carolina

Completed

tAN to Mitigate Withdrawal Behaviors in Neonates

Neonatal Abstinence Syndrome

United States
ONY

Completed

Comparison of Aerosol Delivery of Infasurf to Usual Care in Spontaneously Breathing RDS Patients

Respiratory Distress Syndrome

United States
Aerogen Pharma Limited

Active, not recruiting

A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact

Respiratory Distress Syndrome in Premature Infant

United States, Canada
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia (RADICHOL 1)

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Taiwan, Brazil, Canada, South Africa, United Kingdom, Singapore
Novartis Pharmaceuticals

Completed

A Study of Tobramycin Inhalation Powder From a Modified Manufacturing Process Versus Placebo (EDIT)

Cystic Fibrosis

Russian Federation, Egypt, Romania, Estonia, Latvia, Lithuania, Bulgaria, South Africa, India
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Inhaled Therapy Adherence and Outcomes to Kaftrio in Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Evaluation of a Behavioural Intervention Using App Technology in CF (EAT-CF)

Cystic Fibrosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Using Remote Telemonitoring to Detect Early Decline in Lung Function & Streamline Clinics in Adults With Cystic Fibrosis (RIGHT-CF)

Cystic Fibrosis

United Kingdom
AlgiPharma AS
AlgiPharma Australia Pty. Ltd.

Unknown

A Phase 2b Randomised, Placebo Controlled Study of OligoG in Patients With Cystic Fibrosis

Cystic Fibrosis

Australia
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Pilot Study of Behavioural Intervention for Nutrition in Cystic Fibrosis (PIN-CF)

Cystic Fibrosis

United Kingdom
Krystal Biotech, Inc.
Novotech (Australia) Pty Limited

Withdrawn

A Study of Inhaled KB407 for the Treatment of Cystic Fibrosis

Cystic Fibrosis

Australia
Mucpharm Pty Ltd
St George Hospital, Australia; Mobius Medical Pty Ltd.

Completed

Nebulised BromAc in Healthy Volunteers

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome | Bromelains Adverse Reaction | Acetylcysteine Adverse Reaction | Mucus; Plug

Australia
Australian and New Zealand Intensive Care Research...

Terminated

A Multi-centre Trial of an Open Lung Strategy Including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in Patients With Acute Respiratory Distress Syndrome (PHARLAP)

Acute Respiratory Distress Syndrome

Australia, Ireland, United Kingdom, New Zealand, Saudi Arabia
Chiesi Farmaceutici S.p.A.

Completed

A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)

Respiratory Distress Syndrome, Newborn

United States
Cynata Therapeutics Limited
Cerebral Palsy Alliance

Completed

The MEseNchymal coviD-19 Trial: MSCs in Adults With Respiratory Failure Due to COVID-19 or Another Underlying Cause (MEND)

Covid19 | Acute Respiratory Distress Syndrome

Australia
The University of Texas Health Science Center,...

Unknown

Bevacizumab Eliminates the Angiogenic Threat for Retinopathy of Prematurity (BEAT-ROP)

Retinopathy of Prematurity

United States
Evolve BioSystems, Inc.

Completed

The EFFECT Study: Probiotic and HMO Supplementation in Infants (EFFECT)

Infant Gut Microbiome

United States
The University of Queensland
Telethon Kids Institute

Completed

Prevention of Bronchiectasis in Infants With Cystic Fibrosis (COMBATCF)

Bronchiectasis | Cystic Fibrosis

Australia, New Zealand

Clinical Trials on Infant Newborn in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Turkmenistan

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Rare Diseases

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Dietary Supplements

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