Clinical Trials on Infarction in South Africa

Total 846 results

National Institute of Allergy and Infectious Diseases...
Sanofi; GlaxoSmithKline; Bill and Melinda Gates Foundation

Completed

Pivotal Phase 2b/3 ALVAC/Bivalent gp120/MF59 HIV Vaccine Prevention Safety and Efficacy Study in South Africa (HVTN702)

HIV Infections

South Africa
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of Age

HIV-1-infection

United States, Brazil, South Africa, Uganda, Botswana, Thailand
Elpen Pharmaceutical Co. Inc.

Completed

Eplerenone in Heart Failure Treatment (INOSET)

Heart Failure | Hypertension | Acute Myocardial Infarction

Greece
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Biofabri, S.L

Recruiting

Evaluating the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South Africa (HVTN605A5421)

Tuberculosis | HIV I Infection

South Africa
The University of Queensland
Australasian Society for Infectious Diseases; International Society of Chemotherapy and other collaborators

Terminated

RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp. (MERINO)

Bloodstream Infections

Australia, Singapore, South Africa, Italy, Saudi Arabia, Canada, Lebanon, New Zealand, Turkey
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma (REACT-KS)

Kaposi's Sarcoma | HIV-1 Infection

Peru, Kenya, Malawi, Brazil, South Africa, Uganda
Debiopharm International SA

Recruiting

Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus

Bone or Joint Infection

United States, Ukraine, Argentina, South Africa, Georgia
University of Melbourne

Recruiting

Improving Early Reperfusion With Adjuvant Dornase Alfa in Large Vessel Ischemic Stroke (EXTEND-IA DNase)

Ischemic Stroke

Australia
Euphrates Vascular, Inc.

Recruiting

Pulse Endovascular ReperFUSION for Acute Ischemic Stroke (PERFUSION AIS)

Acute Ischemic Stroke AIS | Cerebral Arterial Disease

United States
Wentworth Area Health Services
Abbott

Unknown

Levosimendan Versus Dobutamine in Shock Patients

Septic Shock | Cardiogenic Shock

Australia
University of Washington
Bill and Melinda Gates Foundation

Completed

Herpes Simplex Virus Type 2 (HSV-2) Suppression to Prevent HIV Transmission

HIV Infection | Sexually Transmitted Diseases | Herpes Simplex, Genital

South Africa, Kenya, Botswana, Rwanda, Tanzania, Uganda, Zambia
National Institute of Allergy and Infectious Diseases...
Microbicide Trials Network

Completed

Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in Women

HIV Infections

South Africa, Uganda, Zimbabwe
TaiGen Biotechnology Co., Ltd.

Completed

Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections

Diabetic Foot Infections

Taiwan, United States, South Africa, Thailand
University of Michigan
Harvard School of Public Health (HSPH); Universidad de Costa Rica

Completed

A Case-control Study of Costa Rican Adults With Myocardial Infarction

Myocardial Infarction, Acute

Costa Rica
Medical University of South Carolina
Memorial Sloan Kettering Cancer Center; Ralph H. Johnson VA Medical Center

Completed

Efficacy Of Copper To Reduce Acquisition Of Microbes and Healthcare-acquired Infections

Healthcare-acquired Infection

United States
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

A Nurse Case Management Intervention to Improve MDR-TB/HIV Co-Infection Outcomes

HIV | MDR-TB

South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Study of Options for Second-Line Effective Combination Therapy (SELECT) (SELECT)

HIV-1 Infection

Peru, Kenya, Malawi, Brazil, South Africa, Zimbabwe, India, Thailand, Tanzania
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV

HIV Infection | Tuberculosis

Peru, Brazil, South Africa, Haiti, Kenya
Institut Pasteur
Institut Pasteur de Bangui

Completed

Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum (MACOMBA)

HIV Infection | Malaria in Pregnancy

Central African Republic
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women

HIV Infections

United States, Malawi, South Africa, Zambia, Zimbabwe
Wits Health Consortium (Pty) Ltd
Fred Hutchinson Cancer Center; Janssen Vaccines & Prevention B.V.; Right to Care and other collaborators

Recruiting

Sisonke 2 - A COVID-19 Vaccine Boost Open Label Study. (Sisonke Boost)

SARS CoV 2 Infection

South Africa
Spero Therapeutics
GlaxoSmithKline

Recruiting

A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (PIVOT-PO)

Urinary Tract Infection | Acute Pyelonephritis

Moldova, Republic of, Georgia, United States, Serbia, Bulgaria, Romania, South Africa
Zimmer Biomet

Recruiting

Zimmer® Natural Nail® (ZNN) Bactiguard Tibia Post-Market Clinical Follow-up Study

Tibial Fractures | Fracture Infection

United Kingdom, Germany, Italy, Switzerland, South Africa, Spain, France, Austria
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); United States...

Completed

Assess Therapeutic Efficacy and Emergence of HIV Drug Resistance Following Initiation of TLD

HIV-1-infection

Kenya, South Africa, Haiti, Malawi, Uganda, Zimbabwe
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection in Women

HIV Infections

South Africa, Zimbabwe, Malawi, Botswana, Kenya, Mozambique, Tanzania
Monash University
The Alfred

Recruiting

Duration of Cardiac Antimicrobial Prophylaxis Outcomes Study (CALIPSO)

Surgical Site Infection

Australia, New Zealand
Sanford Health

Unknown

Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application

Surgical Site Infection | Bacterial Colonization | Lower Extremity Surgery | Surgical Antiseptic

United States
Pfizer
ViiV Healthcare

Terminated

A Long Term Safety Study Of Lersivirine For The Treatment Of HIV-1 Infection In Subjects Who Have Completed Treatment With Lersivirine In Studies A5271015 And A5271022

HIV-1

South Africa, Australia, United Kingdom, Canada, Italy, Poland, Switzerland, Mexico, Brazil
Sanofi
Bristol-Myers Squibb

Completed

Clopidogrel as Adjunctive Reperfusion Therapy - Thrombolysis in Myocardial Infarction (CLARITY-TIMI28)

Acute Coronary Syndromes

Russian Federation, Belgium, Brazil, France, Germany, Hungary, Italy, Mexico, Netherlands, South Africa, Spain, Sweden, United States, Argentina, Australia, Ireland, Israel, Turkey, Austria, Poland, Canada, Portugal, Puerto Rico, United...
GlaxoSmithKline

Terminated

Evaluation of the Safety, Tolerability and Pharmacokinetics of Repeat Oral Doses of GSK580416

Infections, Bacterial | Bacterial Infection

Australia
University of Sydney
Genentech, Inc.

Recruiting

A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients. (RESTORE-MI)

STEMI | Elevated IMR (>32)

Australia, New Zealand
PENTA Foundation
Baylor College of Medicine; University Hospital Birmingham NHS Foundation Trust and other collaborators

Recruiting

DTG/3TC Fixed Dose Formulations for the Maintenance of Virological Suppression in Children With HIV Infection Aged 2 to <15 Years Old (D3 (Penta21))

HIV Infections

Spain, United Kingdom, Thailand, South Africa, Uganda
Merck Sharp & Dohme LLC

Completed

Doravirine/Islatravir (DOR/ISL) in Pediatric Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are <18 Years of Age and Weigh ≥35 kg (MK-8591A-028)

HIV-1 Infection

United States, Italy, Russian Federation, South Africa, Thailand
National Institute of Allergy and Infectious Diseases...

Completed

Acute HIV Infection Observational Study

HIV Infections

United States, Malawi, South Africa, Tanzania, Uganda
Henry M. Jackson Foundation for the Advancement...
Infectious Diseases Clinical Research Program

Completed

Screening for Latent Tuberculosis Infection (LTBI) in US Army Recruits (LTBI)

Latent Tuberculosis Infection

United States
Ark Biosciences Inc.

Terminated

A Study of AK0529 in Infants Hospitalized With RSV

Respiratory Syncytial Virus Infections

Australia
South West Sydney Local Health District

Recruiting

Capnodynamic Monitoring of Cardiorespiratory Function in Critically Ill Patients (PROFICIENT)

Sepsis | Acute Respiratory Infection | Postoperative Respiratory Distress

Australia
Medtronic Cardiac Rhythm and Heart Failure

Completed

Improve SCA Bridge Study

Acute Myocardial Infarction | Sudden Cardiac Arrest

Korea, Republic of, Saudi Arabia, Taiwan, China, Thailand, Singapore, Malaysia, India, Indonesia, South Africa, Bangladesh, Brunei Darussalam, Egypt, Pakistan, Philippines, Tunisia
Medical University of South Carolina

Completed

Use of Novel Sinusonic Device for Prevention of Community Acquired Upper Respiratory Infection (URI)

Upper Respiratory Infection

United States
Centers for Disease Control and Prevention
British Medical Research Council

Recruiting

Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine Given Daily for LTBI (ASTERoiD)

Latent Tuberculosis

Australia, United States, Canada, South Africa
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
Sanford Health

Completed

Prevalence of Human Papillomavirus in Men Living in the Northern Plains

Human Papillomavirus Infection

United States
Leiden University Medical Center

Recruiting

Patient Satisfaction and Long-term Safety of Intravesical Aminoglycoside Instillations in UTI Prevention (INSTILMENT)

Urinary Tract Infections | Recurrent Urinary Tract Infection

Netherlands
GlaxoSmithKline

Completed

A Three-Part Study Of GSK580416 In Healthy Subjects

Infections, Bacterial | Respiratory Tract Infection

Australia
Hippocration General Hospital

Not yet recruiting

Transcutaneous Vagal Nerve Stimulation to Prevent Tachyarrhythmias in Patients Early Following Myocardial Infarction (EARLY-VAGUS)

Myocardial Infarction | Tachyarrhythmia

Greece, United States, United Arab Emirates
Neurobiological Technologies

Terminated

Ancrod (Viprinex™) for the Treatment of Acute, Ischemic Stroke

Stroke | Brain Infarction | Cerebral Ischemia

Taiwan, United States, Australia, South Africa, Canada, Czech Republic, Netherlands, Poland, Russian Federation, United Kingdom
Erasmus Medical Center

Completed

PULsecath mechanicaL Support Evaluation (PULSE)

Coronary Artery Disease | Heart Failure | Cardiogenic Shock

France, Netherlands, United Kingdom
Swisse Wellness Pty Ltd
Commonwealth Scientific and Industrial Research Organisation, Australia

Completed

High Strength Cranberry Supplementation for Prevention of Recurrent Urinary Tract Infection

Urinary Tract Infection

Australia
University of Sydney

Unknown

Partially HLA-matched Third Party Antigen Specific T-cells for Infection Post-stem Cell or Solid Organ Transplantation (R3ACT)

CMV Infection | EBV | Adenovirus

Australia
Cerebrotech Medical Systems, Inc.

Completed

Volumetric Integral Phase-shift Spectroscopy for Noninvasive Detection of Hemispheric Bioimpedance Asymmetry in Acute Brain Pathology (VITAL)

Stroke | Hemorrhage | Ischemic Stroke | Cerebral Infarction | Subarachnoid Hemorrhage | Cerebral Hemorrhage | Stroke, Acute | Intracerebral Hemorrhage | Cerebral Stroke | Clot (Blood); Brain | Intracerebral Injury

United States

Clinical Trials on Infarction in South Africa

Sponsors and Collaborators

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CROs in Jordan

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