Clinical Trials on Intracranial Surgery in South Africa

Total 161 results

University of Cape Town
Bill and Melinda Gates Foundation

Completed

African Surgical OutcomeS-2 (ASOS-2) Trial (ASOS-2)

Surgery | Morality

South Africa
University of KwaZulu
South African Society of Anaesthesiologists (SASA); South African Vascular...

Completed

South African Surgical Outcomes Study (SASOS)

Mortality Following Noncardiac Surgery

South Africa
University of Cape Town

Completed

BNP Evaluation Before Surgery Study: an Observational Study of Natriuretic Peptide Levels Prior to Surgery. (EPIC-2)

Surgery, Cardiovascular

South Africa
University of KwaZulu
University of Cape Town; African Perioperative Research Group (APORG); Safe Surgery...

Completed

An African, Multi-centre Evaluation of Patient Care and Clinical Outcomes for Paediatric Patients Undergoing Surgery (ASOS-Paeds)

Surgery | Perioperative/Postoperative Complications | Perioperative Outcomes | Outcome Assessment | Prospective Studies | Paediatrics | Hospital Mortality | Paediatric Surgery | Developing Countries

South Africa, Sudan
University of KwaZulu
South African Society of Anaesthesiologists (SASA); Safe Surgery South Africa...

Completed

South African Paediatric Surgical Outcomes Study (SAPSOS) (SAPSOS)

Postoperative Complications | Surgery | Anesthesia | Pediatrics | Child Mortality | Hospital Mortality

South Africa
Aarhus University Hospital
University of Aarhus

Completed

Acute Kidney Injury After Cardiac Surgery: Novel Ultrasound Techniques for Prediction of Acute Kidney Injury

Acute Kidney Injury | Cardiac Surgery | Acute Renal Failure

Denmark, South Africa
Pulsar Vascular

Completed

Adjunctive Neurovascular Support for Wide-neck Aneurysm Embolization and Reconstruction (ANSWER)

Intracranial Aneurysms

United States
Medical University of South Carolina

Completed

COAST: Coiling of Aneurysms Smaller Than 5mm With Hypersoft® and Hydrogel Coils (COAST)

Small Intracranial Aneurysms

United States
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
University of Cape Town
University of Stellenbosch; University of KwaZulu

Recruiting

South African Paediatric Surgical Outcomes Study 2 (SAPSOS2)

Iron Deficiency Anemia | Anaemia | Iron | Prospective Studies | Paediatric Surgery | Interventional Studies

South Africa
Icahn School of Medicine at Mount Sinai
Kaneka Corporation

Recruiting

Kaneka iED Coil System for the Treatment of Wide Necked Ruptured and Unruptured Intracranial Aneurysms (CLASS)

Intracranial Aneurysms | Wide Neck Intracranial Aneurysms

United States
Medical University of South Carolina
University of California, Los Angeles; University of Southern California; Augusta...

Completed

Pilot Study of Pre-Ischemic Conditioning for Intracranial Atherosclerosis (PICASSO)

Intracranial Atherosclerosis

United States
Medical University of South Carolina

Completed

A Trial of Adding Lung Protective Strategies to Existing Enhanced Recovery After Surgery (ERAS) Protocols and Its Effects on Improving Post-Operative Lung Function

Colorectal Surgery | Hepatobiliary Surgery

United States
Aretaieio Hospital

Unknown

The Effect of Volatile Anesthetics Sevoflurane and Desflurane on Liver, Renal and Cardiovascular Systems During Liver Surgery

Liver Surgery | Apoptosis

Greece
Medical University of South Carolina

Terminated

LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling Therapy (LARGE)

Intracranial Aneurysm

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

Investigating the Tolerability and Feasibility of Transcutaneous Vagus Nerve Stimulation Following Aneurysmal Subarachnoid Haemorrhage (tVNS in aSAH)

Subarachnoid Haemorrhage From Cerebral Aneurism Rupture

United Kingdom
Microvention-Terumo, Inc.

Completed

Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device (LVIS)

Intracranial Aneurysms

United States
Eyegate Pharmaceuticals, Inc.

Completed

Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")

Refractive Surgery | Ophthalmology | Photorefractive Keratectomy ("PRK") | Laser Assisted Surgery

United States
Medical University of South Carolina

Completed

A Pilot Trial to Determine the Effective N-acetylcysteine Dose for Opioid Reduction for Spine Surgery.

Surgery

United States
Medical University of South Carolina

Completed

QL vs LP Blocks for Analgesia Following THA

Surgery

United States
3M

Recruiting

Continuous Treatment With PREVENA Therapy for 14 Days

Abdominal Surgery | Orthopedic Surgery | Vascular Surgery | Cardiovascular Surgery

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Can the 6MWT Can be Used to Identify Reduced Patient Fitness at Surgical Clinic

Surgery

United Kingdom
Medical University of South Carolina

Completed

Quadratus Lumborum Block for Analgesia Following Hip Arthroscopy

Surgery

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Terminated

Do Noise Cancelling Headphones Reduce Sedation Requirements in Primary Knee Arthoplasty (NOISE)

Anaesthesia | Knee Surgery

United Kingdom
Mercy Health Ohio
Stryker Neurovascular

Unknown

TARGET Intracranial Aneurysm Coiling Registry (TARGET)

Intracranial Aneurysms

United States
BioFirst Corporation

Completed

A Phase I Study of Vitargus® in Vitrectomy

Vitreo-retinal Surgery

Australia
University of KwaZulu
Medical Research Council, South Africa

Completed

African Surgical Outcomes Study (ASOS) (ASOS)

Mortality | Surgery | Surgery- Complications

South Africa, Algeria, Benin, Burundi, Cameroon, Congo, The Democratic Republic of the, Congo, Egypt, Ethiopia, Gambia, Ghana, Kenya, Libyan Arab Jamahiriya, Madagascar, Mali, Mauritius, Namibia, Nigeria, Niger, Senegal, Tanzania, Tog... and more
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Verbal Probability Expressions in Peri-operative Risk

Surgery--Complications | Risk Reduction

United Kingdom
Gold Coast Hospital and Health Service
Prince of Wales Hospital, Sydney; Sir Charles Gairdner Hospital; Liverpool Hospital...

Unknown

Safety and Clinical Effectiveness of Pipeline™ Shield Devices for Intracranial Aneurysms (SCOPE-AUS)

Subarachnoid Hemorrhage | Cerebral Hemorrhage | Neurologic Disorder | Stroke, Acute | Cerebral Aneurysm | Intracranial Aneurysm | Cerebral Stroke

Australia
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Amgen

Completed

Effect of Denosumab on Inflammatory Osteolytic Lesion Activity in Total Hip Arthroplasty

Revision Surgery of Total Hip Arthroplasty

United Kingdom
Allergan

Completed

A Study to Compare the Safety and Efficacy of a New Eye Drop Formulation With REFRESH PLUS® in Participants Following LASIK Refractive Surgery

Bilateral LASIK Surgery

Australia, Canada
Minimally Invasive Devices, Inc.

Completed

Comparison FloShield Air System Versus Clearify Visualization System (D-HELP)

Laparoscopic Surgery

United States
Edwards Lifesciences

Completed

Assisted Fluid Management IDE Study (AFM)

Abdominal Surgery | Pelvic Surgery | Non-Cardiac/ Non-Thoracic Surgery | Major Peripheral Vascular Surgery

United States
Microvention-Terumo, Inc.

Completed

Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support) (LVIS)

Intracranial Aneurysms

United States
Microvention-Terumo, Inc.

Unknown

The WEB-IT Clinical Study (WEB-IT)

Intracranial Aneurysms | Wide Neck Bifurcation Intracranial Aneurysms

United States, Denmark, Canada, Hungary, Germany, Turkey
Spartanburg Regional Healthcare System
Edward Via Virginia College of Osteopathic Medicine

Completed

The Effectiveness and Safety of Human Lumbar Puncture Assist Device (LPat) (LPat)

Encephalitis | Meningitis | Subarachnoid Hemorrhage | Intracranial Neoplasm | Guillain-Barré | Intracranial CNS Disorder

United States
Cerus Endovascular, Ltd

Recruiting

US IDE Study of the Contour NEurovasCular System™ for IntraCranial Aneurysm Repair (NECC)

Aneurysm, Intracranial

United States
The George Institute
University of Sydney

Terminated

Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial Magnetic Resonance Imaging Sub-study (TRIDENT-MRI)

Stroke | Hypertension | Cerebral Small Vessel Diseases | Vascular Dementia | Intracerebral Hemorrhage

Australia
Vance Thompson Vision
Ocular Therapeutix, Inc.

Completed

The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospective Study

Refractive Surgery

United States
J. Mocco
University at Buffalo; MOUNT SINAI HOSPITAL

Completed

INVEST Feasibility - Minimally Invasive Endoscopic Surgery With Apollo in Patients With Brain Hemorrhage

Intracranial Hemorrhage

United States
J. Mocco
University at Buffalo; MOUNT SINAI HOSPITAL

Completed

INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage

Intracranial Hemorrhage

United States
Microvention-Terumo, Inc.

Completed

Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms (FRED)

Intracranial Aneurysms

United States, Japan
Medical University of South Carolina
Massachusetts General Hospital; University of Miami; Yale University; University... and other collaborators

Active, not recruiting

Registry of Emergent Large veSsel oCclUsion duE to IntraCranial AtherosclerosiS (RESCUE-ICAS)

Large Vessel Occlusion | Mechanical Thrombectomy | Intracranial Stenosis

United States, Switzerland, Germany, Italy, Portugal, Saudi Arabia
The George Institute
National Health and Medical Research Council, Australia

Completed

Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage

Intracranial Hemorrhages | Cerebral Hemorrhage | CVA (Cerebrovascular Accident)

Australia, New Zealand, China
Medical University of South Carolina

Completed

Transcranial Magnetic Stimulation Effects on Pain Perception (TMS)

Gastric Bypass Surgery Pain Management

United States
Medical University of South Carolina

Withdrawn

Accuracy of the Pentacam and IOL Master to Calculate the Effective Corneal Power After Corneal Refractive Surgery

Cataract Extraction | Refractive Surgery

United States
Medical University of South Carolina

Completed

Evaluation of the Aspheric ReSTOR Intraocular Lens (IOL) After Routine Cataract Extraction

Cataract Extraction | Refractive Surgery

United States
Invex Therapeutics Ltd.
Premier Research Group plc; University Hospitals Birmingham Neuro Ophthalmology... and other collaborators

Terminated

A Trial to Determine the Efficacy and Safety of Presendin in IIH (IIH EVOLVE)

Idiopathic Intracranial Hypertension

Israel, Germany, Australia, United States, United Kingdom, New Zealand
Duke University
Daiichi Sankyo, Inc.; Medtronic; Chiesi Farmaceutici S.p.A.

Completed

IMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke Care

Intracranial Hemorrhages | Subarachnoid Hemorrhage | Acute Stroke

United States
The George Institute
University of Sydney

Terminated

Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study (TRIDENT COG)

Hypertension | Cerebral Small Vessel Diseases | Dementia, Vascular | Stroke Hemorrhagic | Cognitive Decline | Intracerebral Hemorrhage

Australia, Netherlands

Clinical Trials on Intracranial Surgery in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bahrain

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Rare Diseases

Drug Interventions

Dietary Supplements

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