Clinical Trials on Intracranial Atherosclerotic Disease

Total 379339 results

Beijing Tiantan Hospital

Recruiting

Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial (DREAM-PRIDE)

Stroke | Intracranial Atherosclerotic Disease

China
Montreal Heart Institute

Completed

Colchicine in Vascular Inflammation Assessed With PET Imaging (COLPET)

Atherosclerotic Vascular Disease

Canada
Brigham and Women's Hospital

Terminated

The Effect(s) of Sevelamer Carbonate (Renvela) on Atherosclerotic Plaque Inflammation Judged by FDG-PET Scan

Inflammation | Cardiovascular Disease | Atherosclerosis | Hyperphosphatemia | Dialysis

United States
Sheba Medical Center
Carmel Medical Center; University Hospital Goettingen; CVPath Institute Inc.

Unknown

Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques

Peripheral Vascular Diseases | Atherosclerosis | Aortic Aneurysm

Israel
Novartis Pharmaceuticals

Not yet recruiting

VictORION-INCLUSION is a Multicenter, Randomized, Open Label, Study of Inclisiran + Usual Care vs Usual Care Alone in an Inclusive and Underrepresented Population at High Risk for or Diagnosed With ASCVD Within a Pragmatic EHR Framework. (V-INCLUSION)

Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals

Completed

A Randomized Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE) (V-INITIATE)

Atherosclerotic Cardiovascular Disease

United States
Creighton University

Completed

Utility of Clinical Examination in the Noninvasive Prediction of Aortic Atheroma - A Prospective Study

Atherosclerosis

United States
Xiang Xie
Xinjiang Medical University

Not yet recruiting

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Cancer | Atherosclerotic Cardiovascular Disease | ASCVD | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Icahn School of Medicine at Mount Sinai
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study (CIRT)

Atherosclerotic Cardiovascular Disease | Vascular Inflammation

United States, Canada
University of Helsinki
University of Eastern Finland

Completed

The Influence of Dietary Plant Sterols and Plant Stanols on Cholesterol and Plant Sterol Levels in Atheromatous Plaques

Atherosclerosis

Finland
Massachusetts General Hospital

Completed

Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque (BRIGHT-CEA)

Atherosclerosis | Carotid Stenosis | Atherosclerotic Plaque

United States
National Cerebral and Cardiovascular Center

Unknown

Atheroma Progression and Vulnerability Under Continuous Glucose Monitoring (OPTIMAL)

Coronary Atherosclerosis

Japan
Jordan Collaborating Cardiology Group

Terminated

Tracking of Lipid Lowering Therapy in Jordan (JoLLA)

Dyslipidemias | Atherosclerotic Cardiovascular Disease

Jordan
Aristotle University Of Thessaloniki

Completed

Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque

Stroke | Metabolic Syndrome | Type 2 Diabetes | Carotid Atherosclerosis

Greece
University of Louisville

Recruiting

Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) (ARTCAP)

Coronary Artery Disease | Atherosclerosis | Heart Attack

United States
Esperion Therapeutics, Inc.

Completed

Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
University of Vermont
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Epidemiology of Vascular Inflammation & Atherosclerosis

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Atherosclerosis | Coronary Arteriosclerosis | Cerebrovascular Accident | Cerebral Arteriosclerosis
Aristotle University Of Thessaloniki

Unknown

Coronary Artery Geometry and the Severity of Coronary Atherosclerosis (GEOMETRY-CTA)

Coronary Artery Disease | Atherosclerosis | Stable Angina | Atherosclerotic Plaque

Greece
Northwell Health

Active, not recruiting

The Young Heart Study

Coronary Artery Disease | Atherosclerotic Cardiovascular Disease

United States
Novartis Pharmaceuticals

Completed

In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease (SIRIUS)

Atherosclerotic Cardiovascular Disease

France
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Cardiovascular Diseases | Atherosclerosis | Hypertriglyceridemia

United States, Spain, Italy, Denmark, Hungary, Netherlands, Canada, France, Poland, Bulgaria, Czechia, Portugal, Slovakia, Norway
Second Affiliated Hospital, School of Medicine,...

Withdrawn

Study of Urinary Kallikrein to Enhance Collateral Circulation in Symptomatic Intracranial Atherosclerosis

Intracranial Arteriosclerosis | Collateral Circulation | Anterior Cerebral Circulation Infarction

China
Sanofi
Regeneron Pharmaceuticals

Completed

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Atherosclerotic Cardiovascular Disease

China, Hong Kong, Austria, Bulgaria, Norway, Peru, France, Japan, Spain, Lithuania, Philippines, Israel, Belgium, Croatia, Poland, Hungary, Chile, Mexico, Latvia, Singapore, Switzerland, Colombia, Greece, Ukraine, Turkey, Finland, United States and more
Tabba Heart Institute
Getz Pharma

Recruiting

Pakistan Study of Premature Coronary Atherosclerosis in Young Adults (PAKSEHAT)

Stroke | Hypertension | Diabetes Mellitus, Type 2 | Atherosclerotic Plaque

Pakistan
China National Center for Cardiovascular Diseases

Not yet recruiting

Natural History of Coronary Atherosclerosis (NASCENT)

Coronary Artery Disease Progression | Optical Coherence Tomography | Atherosclerotic Lesion | Radial Wall Strain
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events (SANTORINI)

Cardiovascular Diseases | Dyslipidemia | Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Finland, Netherlands, Spain, Belgium, Sweden, Austria, United Kingdom, Switzerland, Denmark, France, Germany, Portugal, Italy, Ireland
Canadian Atherosclerosis Imaging Network
Canadian Institutes of Health Research (CIHR)

Completed

Correlation Between Coronary and Carotid Atherosclerotic Disease (CAD) and Links With Clinical Outcomes

Atherosclerosis

Canada
Assaf-Harofeh Medical Center

Completed

Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation

Atherosclerosis

Israel
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cholesterol-Lowering Atherosclerosis Study (CLAS)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Cerebrovascular Disorders | Coronary Disease | Arterial Occlusive Diseases | Atherosclerosis | Carotid Artery Diseases | Coronary Arteriosclerosis | Cerebral Arteriosclerosis
Esperion Therapeutics, Inc.

Completed

Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk (CLEAR Wisdom)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
Ionis Pharmaceuticals, Inc.

Completed

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia

Hypertriglyceridemia | Atherosclerotic Cardiovascular Disease | Severe Hypertriglyceridemia

United States, Canada
State University of Maringá

Completed

Short-term Changes on C-Reactive Protein (CRP) Levels After Non-surgical Periodontal Treatment

Chronic Periodontitis | Atherosclerotic Cardiovascular Disease

Brazil
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Reducing Total Cardiovascular Risk in an Urban Community (COACH)

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Hypertension | Diabetes Mellitus | Atherosclerosis | Cerebral Arteriosclerosis

United States
Case Western Reserve University
National Institute of Neurological Disorders and Stroke (NINDS)

Not yet recruiting

REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis

Stroke | Hemodynamics | Intracranial Atherosclerotic Disease | Angioplasty, Balloon | Device Safety

United States
Assiut University

Unknown

Predictors of Subclinical Atherosclerotic Cardiovascular Diseases (ASCVD) in Patients With Inflammatory Bowel Disease

Inflammatory Bowel Diseases
University Hospital, Grenoble

Recruiting

Impact of PCSK9 Inhibitors on Coronary Microvascular Dysfunction in Patients With Atherosclerotic Cardiovascular Disease Proved by Myocardial Ischemia and Needing Coronarography (MICROPROTECT)

Atherosclerotic Cardiovascular Disease

France
The Medicines Company

Completed

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol (ORION-10)

Elevated Cholesterol | ASCVD

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gene-by-Smoking Interactions and Risk of Atherosclerosis - Ancillary to ARIC

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Peripheral Vascular Diseases | Atherosclerosis | Carotid Artery Diseases | Cerebrovascular Accident | Cerebral Arteriosclerosis
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intolerant (CLEAR Serenity)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease | Statin Adverse Reaction

United States, Canada
Stanford University

Active, not recruiting

Incidental Coronary Calcification Quality Improvement Project (ICC QI)

Coronary Artery Disease | Atherosclerotic Cardiovascular Disease

United States
Korea University Guro Hospital

Recruiting

Comprehensive Assessment of Interconnection Between Brain Emotional Activity and Coronary Plaque Instability

Inflammation | Atherosclerosis | Acute Coronary Syndrome | Emotional Stress | Atherosclerosis, Coronary | Hematopoiesis | Atherosclerosis Coronary Artery With Angina Pectoris | Atheroma; Heart

Korea, Republic of
Population Health Research Institute

Completed

Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease

Ischemic Stroke | Intracranial Atherosclerotic Disease

Canada
University of Florida

Completed

Transcranial Doppler Ultrasound Monitoring During Flow-Diverter Embolization

Intracranial Aneurysm | Aneurysm, Intracranial | Giant Intracranial Aneurysm

United States
National Institute of Diabetes and Digestive and...

Completed

Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CT

HIV Infections | Cardiovascular Disease | Atherosclerosis | HIV/AIDS | Insulin Resistance

United States
Sanofi

Completed

Non-interventional Study on the Monthly Administration of 300 mg AliRocumab (PRALUENT®) With the 2 ml SYDNEY Auto-injector (MARS)

Atherosclerotic Cardiovascular Disease | Primary Hypercholesterolaemia and Mixed Dyslipidaemia

Germany
Radboud University Medical Center
Dutch Heart Foundation

Completed

Time Restricted Eating and Innate Immunity (SIGNATURE)

Myocardial Infarction | Atherosclerotic Cardiovascular Disease | Time Restricted Feeding

Netherlands
Microvention-Terumo, Inc.

Unknown

The WEB-IT Clinical Study (WEB-IT)

Intracranial Aneurysms | Wide Neck Bifurcation Intracranial Aneurysms

United States, Denmark, Canada, Hungary, Germany, Turkey
Medical University of South Carolina

Recruiting

Stroke Thrombectomy and Aneurysm Registry (STAR)

Stroke | Thromboses, Intracranial | Aneurysm, Brain

United States, Spain, Korea, Republic of, Germany, Switzerland, Canada, Argentina, Japan, Portugal, Uruguay, Egypt
Assiut University

Unknown

Normal Parameters of Cranial Vessels Using Cranial Vascular Duplex Among Egyptian Population

Atherosclerosis | Atheroma of Cerebral Arteries | Atheroma; Carotid Artery | Atheroma; Cerebral
Lashmi Venkatraghavan
University Health Network, Toronto

Completed

Optic Nerve Sheath Diameter (ONSD) With the Raised PCO2 and Internal Jugular Venous Occlusion

Elevated Intracranial Pressure (ICP)

Canada

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