Clinical Trials on Investigating Spinal Atrophy in Patients With Spinal Injury in United States

Total 47 results

Mayo Clinic

Completed

Safety of Spine Radiofrequency Procedures

Radiofrequency Ablation in Patients With Spinal Hardware

United States
Kevin Kilgore
National Institute of Neurological Disorders and Stroke (NINDS); Case Western... and other collaborators

Recruiting

Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury (NNP-UE+T)

Spinal Cord Injuries | Spinal Cord Injury at C5-C7 Level | Spinal Cord Injury Cervical | Spinal Cord Injury at C5-C7 Level With Complete Lesion | Spinal Cord Injury at C5-C7 Level With Incomplete Lesion

United States
Grand Valley State University

Active, not recruiting

Pediatric Powered Wheelchair Standing Devices: An Exploratory Study

Cerebral Palsy | Spinal Cord Injuries | Spinal Muscular Atrophy | Genetic Disease | Spina Bifida | Development Delay

United States
Hospital for Special Surgery, New York

Recruiting

ESP Block in MIS Lumbar Spine Surgery

Patients With Spinal Stenosis Indicated for MIS TLIF

United States
Hospital for Special Surgery, New York

Withdrawn

Indirect vs. Direct Decompression for Treatment of Central Stenosis: RCT (IDVD)

Patients With Spinal Stenosis Indicated for LLIF

United States
Harvard Medical School (HMS and HSDM)
Boston Children's Hospital; Ashwini Health System, Gudalur, India; Harvard Center... and other collaborators

Completed

Task-based Credentialing for Medical Officers in Spinal Anesthesia

Spinal Anesthesia | Task Sharing in Anesthetic Delivery in Areas With Limited Access to Care

United States, India
Ohio State University

Completed

Metabolic Health in Individuals With Spinal Cord Injury (SCI) (SCI)

Spinal Cord Injuries | Metabolic Disease | Skeletal Muscle Atrophy

United States
National Institutes of Health Clinical Center (CC)

Recruiting

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

Cerebral Palsy | Muscular Dystrophy | Spina Bifida | Incomplete Spinal Cord Injury

United States
National Institutes of Health Clinical Center (CC)

Recruiting

Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders

Cerebral Palsy | Muscular Dystrophy | Spina Bifida | Incomplete Spinal Cord Injury

United States
Universidad Autonoma de Madrid
King's College London; Centro Superior de Estudios Universitarios Lasalle

Completed

50% Body Weight Reverses Stature, Lumbar Disc Expansion and Vertebral Compliance by Hyper-Buoyancy Floatation.

Muscle Atrophy | Intervertebral Disc Compression | Spine Injury

Spain, United Kingdom
Icahn School of Medicine at Mount Sinai

Completed

Exoskeleton-assisted Walking in SCI Inpatient Rehabilitation

Spinal Cord Injuries | Inpatients

United States
University of Miami
Florida

Recruiting

Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)

Insulin Resistance | Spinal Cord Injuries | Tetraplegia | Muscle Loss | Paraplegia | Atrophy, Muscular

United States
University of Utah

Completed

High-Resolution Diffusion Tensor Imaging (DTI) of the Cervical Spinal Cord in the Setting of Spinal Cord Injury (SCI)

Spinal Cord Injury | Cervical Spondylosis With Myelopathy | Degenerative Disorder

United States
The Alfred E. Mann Foundation for Scientific Research
Walter Reed Army Medical Center

Terminated

Use of Implanted Microstimulators for Decreasing Spasticity and Improving Motion Following Spinal Cord Injury

Spinal Cord Injury at C5-C7 Level With Incomplete Lesion

United States
Synchron Medical, Inc.

Active, not recruiting

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

Paralysis | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Neurologic Disorder | Spinal Muscular Atrophy | Cervical Spinal Cord Injury | Stroke, Lacunar | Paralysis; Stroke | Stroke Brainstem | Tetraplegic; Paralysis | Quadriplegia/Tetraplegia

United States
Georgetown University
Solstice Neurosciences

Completed

Myobloc Atrophy Study (MAS)

Stroke | Brain Injury | Tumor | Spinal Cord Injury (SCI) | Spasticity Secondary to Either a Disorder or Trauma

United States
Nemours Children's Clinic

Recruiting

Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases

Charcot-Marie-Tooth Disease | Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Muscular Atrophy | Neuromuscular Disease | Spinal Muscular Atrophy With Respiratory Distress 1 | Peroneal Muscular Atrophy

United States
University of Michigan
National Institute on Disability, Independent Living, and Rehabilitation...

Completed

Clinical Trial of a Serious Game for Individuals With SCI/D

Spinal Cord Diseases | Spinal Stenosis | Spinal Cord Injury | Spina Bifida | Syringomyelia | Spinal Neoplasms | Transverse Myelitis | Spinal Cord Involvement | Polio and Post-polio Syndrome

United States
University of Kansas

Completed

A Randomized Exercise Trial for Wheelchair Users

Stroke | Multiple Sclerosis | Cerebral Palsy | Arthritis | Muscular Dystrophy | Amputation | Spinal Cord Injury | Spina Bifida

United States
Karunesh Ganguly
National Institute on Deafness and Other Communication Disorders (NIDCD)

Recruiting

ECoG BMI for Motor and Speech Control (BRAVO)

Stroke | Multiple Sclerosis | Muscular Dystrophies | ALS | SCI - Spinal Cord Injury

United States
AstraZeneca

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease (HESTIA 1)

Investigation of Platelet Aggregation in Paediatric Patients With Sickle Cell Disease

United States, Canada, United Kingdom, South Africa, Lebanon, Kenya
Thomas Jefferson University

Recruiting

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

Stroke | Cerebral Palsy | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Hemiparesis | Spinal Muscular Atrophy | Quadriplegia | Arthrogryposis | Neurologic Diseases | Charcot-Marie-Tooth | Weakness of Extremities as Sequela of Stroke | Weakness Due to Upper Motor Neuron Dysfunction | Arm Paralysis

United States
University of Pittsburgh

Completed

ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis

Muscular Dystrophy | ALS | Spinal Cord Injury | Tetraplegia | Brachial Plexus Injury | Brainstem Stroke

United States
VA Office of Research and Development

Not yet recruiting

iBCI Optimization for Veterans With Paralysis

Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Cord Injury | Brain Stem Infarctions | Locked-in Syndrome

United States
Shirley Ryan AbilityLab
Otto Bock Healthcare Products GmbH

Active, not recruiting

Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis

Arthritis | Spinal Cord Injuries | Poliomyelitis | Post-polio Syndrome | Lower Motor Neurone Lesion

United States
Leigh R. Hochberg, MD, PhD.
National Institute of Neurological Disorders and Stroke (NINDS); US Department... and other collaborators

Recruiting

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia (BrainGate2)

Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Cord Injuries | Tetraplegia | Brain Stem Infarctions | Locked in Syndrome

United States
University of Iowa

Completed

Aspirin Attenuates Inflammation in Human Cerebral Aneurysms

The Focus of the Study is to Monitor MRI Signal Changes and Inflammatory Biomarkers With Use of Aspirin in Patients With Unruptured Cerebral Aneurysm

United States
Oregon Health and Science University

Recruiting

Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit (BCI-FIT)

Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Multiple System Atrophy | Parkinson's Disease and Parkinsonism | Brain Tumor Adult | Locked-in Syndrome | Brainstem Stroke

United States
Leigh R. Hochberg, MD, PhD.
National Institute on Deafness and Other Communication Disorders (NIDCD)

Recruiting

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-01)

Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Tetraplegia | Dysarthria | Brain Stem Infarctions | Locked in Syndrome | Anarthria

United States
Leigh R. Hochberg, MD, PhD.
National Institute on Deafness and Other Communication Disorders (NIDCD)

Recruiting

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02) (BG-Speech-02)

Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Spinal Cord Injuries | Tetraplegia | Dysarthria | Brain Stem Infarctions | Locked-in Syndrome | Anarthria

United States
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Power Over Pain (POP) Study (POP)

Multiple Sclerosis | Low Back Pain | Chronic Pain | Muscular Dystrophies | Spinal Cord Injury | Other and Unspecified Amputation Stump Complications

United States
University of Utah

Completed

Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit

Post-operative Craniotomy Patients | Carotid Endarterectomy and Carotid Artery Stenosis Patients | Post-op Spine Patients Admitted to the NCCU | Endovascular Patients Undergoing Intracranial Intervention | Traumatic Brain Injuries NPO for at Least 12 Hours

United States
University of Washington

Completed

Enhance Wellness for Individuals With Long-Term Physical Disabilities

Multiple Sclerosis | Muscular Dystrophy | Spinal Cord Injury | Post-polio Syndrome

United States
Shirley Ryan AbilityLab

Recruiting

Nomad P-KAFO Study

Multiple Sclerosis | Paralysis | Muscular Dystrophy | Spinal Cord Injuries | Cerebrovascular Accident | Post-polio Syndrome

United States
Casa Colina Hospital and Centers for Healthcare

Completed

Exploring Accessible Beauty for Individuals With Upper Extremity Deficits

Multiple Sclerosis | Amyotrophic Lateral Sclerosis | Muscular Dystrophies | Graves Disease | Myasthenia Gravis | Traumatic Brain Injury | Stroke, Ischemic | Stroke, Acute | Stroke Hemorrhagic | SCI - Spinal Cord Injury | Guillain-Barre Syndrome | Lupus Erythematosus | Stroke (CVA) or TIA | Ehlers-Danlos Syndromes...

United States
University of Pennsylvania
Michael J. Fox Foundation for Parkinson's Research

Completed

Biomarkers in Neural Disorders

Parkinson's Disease | Myasthenia Gravis | Spinal Cord Injuries | Multiple System Atrophy | Progressive Supranuclear Palsy | Essential Tremor | Alzheimer's Disease | Diffuse Lewy Body Disease | Drug Induced Parkinson's Disease

United States
Bastyr University

Recruiting

Modifiable Variables in Parkinsonism (MVP)

Parkinson's Disease | Parkinsonism | Corticobasal Degeneration | Shy-Drager Syndrome | Progressive Supranuclear Palsy | Dementia With Lewy Bodies | MSA - Multiple System Atrophy | Olivopontocerebellar Atrophies | Pick Disease

United States
Beth Israel Deaconess Medical Center
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Innovative Ultrasound Technology in Neuromuscular Disease (AQUIRe)

Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Radiculopathy | Trauma Injury | Orthopedic Disorder | Myopathy | Polyneuropathy and Mononeuropathies

United States
ConvaTec Inc.

Completed

GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology

Multiple Sclerosis | Lower Urinary Tract Symptoms | Parkinson Disease | Spinal Cord Injuries | Bladder Outlet Obstruction | Cauda Equina Syndrome | Detrusor Underactivity | Enlarged Prostate With Lower Urinary Tract Symptoms

United Kingdom, United States, France
University of Massachusetts, Worcester

Enrolling by invitation

Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Frontotemporal Dementia | Miyoshi Myopathy | Amyotrophic Lateral Sclerosis, Sporadic | PLS | Lou Gehrigs Disease | Familial Disease | Amyotrophic Lateral Sclerosis With Dementia

United States
Global Healthy Living Foundation
University of Alabama at Birmingham

Recruiting

PatientSpot Formerly Known as ArthritisPower (GHLF)

Heart Failure | Stroke | Epilepsy | Multiple Sclerosis | Obesity | Diabetes | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Peripheral Arterial Disease | Inflammatory Bowel Diseases | Amyotrophic Lateral Sclerosis | Psoriasis | Asthma | Muscular Dystrophy | Fibromyalgia | Alzheimer... and other conditions

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
MD Stem Cells

Recruiting

Neurologic Stem Cell Treatment Study (NEST)

Stroke | Nervous System Diseases | Diabetic Neuropathies | Neurodegenerative Diseases | Cognitive Impairment | Amyotrophic Lateral Sclerosis | Dementia | Neurological Disorders | Alzheimer Disease | ALS | Traumatic Brain Injury | Cerebral Infarction | Lewy Body Disease | Cerebral Hemorrhage | Frontotemporal Dementia | Progressive... and other conditions

United States, United Arab Emirates
Children's Hospital of Philadelphia
Illumina, Inc.

Active, not recruiting

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

Mucopolysaccharidoses | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2 Gangliosidosis | Zellweger... and other conditions

United States
Cure CMD

Recruiting

Congenital Muscle Disease Study of Patient and Family Reported Medical Information (CMDPROS)

Emery-Dreifuss Muscular Dystrophy | Congenital Myasthenic Syndrome | Limb-Girdle Muscular Dystrophy | Congenital Muscular Dystrophy With ITGA7 (Integrin Alpha-7) Deficiency | Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy and Abnormal Glycosylation of Dystroglycan With Severe Epilepsy) and other conditions

United States
Children's Hospital of Philadelphia
Eli Lilly and Company; University of Pennsylvania; Takeda; National Institute of... and other collaborators

Recruiting

The Myelin Disorders Biorepository Project (MDBP)

Mucopolysaccharidoses | Leukoencephalopathies | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2... and other conditions

United States
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States

Clinical Trials on Investigating Spinal Atrophy in Patients With Spinal Injury in United States

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kuwait

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations