Clinical Trials on Ischemia-reperfusion Injury

Total 22827 results

University of Nottingham
Nottingham University Hospitals NHS Trust; The Stroke Association, United Kingdom

Completed

Psychoeducation for Transient Ischaemic Attack and Minor Stroke (OPTIMISM)

Stroke | Transient Ischaemic Attack

United Kingdom
University of Nottingham

Not yet recruiting

Validation of Renal Perfusion CEUS Against MRI, and Its Application in Acute Kidney Injury

Kidney Diseases | Ultrasonography | Kidney Injury, Acute | Perfusion Imaging

United Kingdom
West China Hospital
National Natural Science Foundation of China; Chengdu University of Traditional... and other collaborators

Completed

Cohort Study for Severe Ischaemic Stroke (SIS)

Severe Ischaemic Stroke | Malignant Ischaemic Stroke

China
Daping Hospital and the Research Institute of Surgery...
Children's Hospital of Chongqing Medical University; Children's Hospital of... and other collaborators

Withdrawn

Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE)

Brain Injury | Hypoxic- Ischemic Encephalopathy | Whole-Body Hypothermia

China
Xiangya Hospital of Central South University

Unknown

Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases

Sepsis | Ischemic Stroke | TBI (Traumatic Brain Injury) | Subarachnoid Hemorrhage, Aneurysmal | ICH - Intracerebral Hemorrhage | HIE - Hypoxic - Ischemic Encephalopathy

China
Children's Hospital Los Angeles

Recruiting

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1) (ICHOR 1)

TBI (Traumatic Brain Injury) | Hypoxic-Ischemic Encephalopathy | Hemodynamic Instability | TBI | HIE

United States
University Hospital, Antwerp

Terminated

CLAD: Finding Biomarkers to Predict Rejection and/ or Outcome After Lung Transplantation

Lung Transplant Failure and Rejection | Primary Graft Dysfunction

Belgium
Assistance Publique Hopitaux De Marseille

Recruiting

Neonatal Hypoxic Ischemic Encephalopathy : Safety and Feasibility Study of a Curative Treatment With Autologous Cord Blood Stem Cells (NEOSTEM)

Neonatal Hypoxic-ischaemic Encephalopathy

France
University Hospital "Sestre Milosrdnice"

Completed

Impact of Injection Pressure on Myocardial Reperfusion During Primary PCI (ImPress)

STEMI - ST Elevation Myocardial Infarction | Myocardial Reperfusion

Croatia
Fundación Pública Andaluza para la gestión de la...

Recruiting

Salicornia for Neurovascular Health Improve

Stroke | Ischemic Stroke | Brain Ischemia | Neurovascular Injury

Spain
Indonesia University
National Cardiovascular Center Harapan Kita Hospital Indonesia

Unknown

The Effect of IABP Early Insertion on Mortality in Post Cardiac Arrest Patients With Acute Coronary Syndrome

Post-Cardiac Arrest Syndrome

Indonesia
University Children's Hospital, Zurich

Completed

Correlation of Risk Factors and Severity of Hypoxic-ischaemic Encephalopathy

Hypoxic Ischaemic Encephalopathy

Switzerland
University of Florence
Sandro Gelsomino; Edvin Prifti; Francesco Cabrucci; Marco Bugetti; Orlando Parise; Aleksander...

Recruiting

Post-Surgery Extracorporeal Life Support (PC-ECLS)

Cardiogenic Shock | Extracorporeal Membrane Oxygenation Complication | Post-cardiac Surgery | Extracorporeal Life Support | Post Cardiac Arrest Syndrome

Italy
Hospital de Clinicas de Porto Alegre

Completed

Hemodynamic Responses of Stable Ischemic Heart Disease Patients to a Comedy Session

Ischaemic Heart Disease

Brazil
Aarhus University Hospital Skejby
Abbott

Active, not recruiting

The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER) (OCTOBER)

Ischemic Heart Disease | Ischaemic Heart Disease

Denmark, United Kingdom, Sweden, Finland, Germany, Belgium, Norway, Poland, Netherlands, Estonia, Ireland, Italy, Latvia
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion and Remote Ischaemic Preconditioning in Man - A Bradykinin Dependent Pathway

Ischaemic Heart Diseases

United Kingdom
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion and Ischaemic Preconditioning on the Endogenous Fibrinolysis in Man

Ischaemic Heart Diseases

United Kingdom
Gilead Sciences

Completed

Effect of Ranolazine on Myocardial Perfusion Assessed by Serial Quantitative Exercise SPECT Imaging

Myocardial Ischemia | Myocardial Perfusion Imaging

United States, Finland, Israel, Canada, Italy, Singapore, Czech Republic, United Kingdom
Advanced Circulatory Systems
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion

Head Injury | Intracranial Pathology | Compromised Cerebral Perfusion

United States
Helsinki University Central Hospital

Recruiting

Neuropsychological Rehabilitation Over the Internet (IRENE)

Encephalitis | Traumatic Brain Injury | Hypoxia-Ischemia, Brain | Brain Hemorrhage | Stroke, Acute Ischemic

Finland
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion in Man - A Bradykinin Dependent Pathway

Ischaemic Heart Diseases

United Kingdom
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-reperfusion on the Endogenous Fibrinolysis in Man

Ischaemic Heart Diseases

United Kingdom
University College Cork
Karolinska Institutet

Completed

BiHiVE2 Study. The Investigation and Validation of Predictive Biomarkers in Hypoxic-ischaemic Encephalopathy. (BiHiVE2)

Asphyxia | Hypoxic Ischaemic Encephalopathy (HIE)

Sweden, Ireland
Tongji Hospital

Unknown

PGE1 Improves Coronary Microcirculation Dysfunction in Patients With CAD and Diabetes

Coronary Microvascular Perfusion in Patients With Ischemic Heart Disease
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress

Ischemic Stress | Transient Non-Lethal Ischemia

United States
University of Padova

Completed

Primary Graft Dysfunction, Pronation, Bilateral Lung Transplants (PGD-PRONATION)

Lung Transplant | Primary Graft Dysfunction

Italy
Advanced Circulatory Systems
United States Army Institute of Surgical Research

Terminated

Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion (4hour)

Head Injury | Intracranial Pathology | Compromised Cerebral Perfusion

United States
Li Haiyan

Unknown

Diagnosis and Treatment of Minor Ischaemic Stroke According to the Etiology and Pathogenesis

Ischaemic Stroke

China
University of Oulu
Helsinki University Central Hospital; Oulu University Hospital; Cerenion Oy

Completed

Propofol-induced EEG Changes in Hypoxic Brain Injury (PROPEA3)

Cardiac Arrest | Hypoxic-Ischemic Encephalopathy

Finland
Turku University Hospital
University of Turku; Academy of Finland

Completed

Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients (Xe-hypotheca)

Ischemic Brain Injury

United States, Finland
Lund University Hospital

Recruiting

Exhaled Breath Particles in Lung Transplantation

Lung Transplant Rejection | Chronic Rejection of Lung Transplant | Primary Graft Dysfunction

Sweden
Apeptico Forschung und Entwicklung GmbH

Completed

Study in Intensive Care Patients Regarding the Effect of Inhaled AP-301 After Primary Graft Dysfunction After Lung Transplantation

PGD Primary Graft Dysfunction

Austria
Boston Children's Hospital

Not yet recruiting

A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

Hypoxic-Ischemic Encephalopathy | Infant Development | Neurodevelopment | HIE
McGill University Health Centre/Research Institute...
Wayne State University; Brown University; Imperial College London; Ohio State University and other collaborators

Completed

Prospective Research in Infants With Mild Encephalopathy (PRIME)

Brain Injury | Hypoxic-Ischemic Encephalopathy | Neonatal Seizure

Canada, United States, Thailand, United Kingdom
Niaz Ahmed

Recruiting

Imatinib in Acute Ischaemic Stroke

Acute Ischaemic Stroke

Sweden
Fundacion para la Investigacion Biomedica del Hospital...

Completed

Efficacy and Security of an Endovascular Treatment as First Choice Procedure Compared With a Standard Intravenous Thrombolytic Therapy Treatment for Patients With Acute Ischemic Stroke Within 4.5 Hours After Onset (FUN-TPA)

Acute Ischaemic Stroke

Spain
Tasly Biopharmaceuticals Co., Ltd.

Completed

Study of rhPro-UK in Patients With Acute Ischaemic Stroke in 4.5 Hours After Stroke Onset(PROST)

Acute Ischaemic Stroke

China
Tasly Biopharmaceuticals Co., Ltd.

Completed

Thrombolysis With rhPro-UK in 4.5-6 Hours After Acute Ischemic Stroke in a Double-blinded,Controlled Trial (PROUD)

Acute Ischaemic Stroke

China
NHS Greater Glasgow and Clyde
University of Edinburgh; Newcastle University; University of Glasgow

Terminated

Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE)

Acute Ischaemic Stroke

United Kingdom
University Hospital, Geneva

Completed

PeRiOperaTivE CardioproTection With Ivabradine in Non-cardiac Surgery (PROTECTIN)

Myocardial Ischemia | Myocardial Injury

Switzerland
Harbin Medical University
The Second Hospital of Hebei Medical University; Beijing Anzhen Hospital; Daqing... and other collaborators

Terminated

Deferred or Immediate Stent Implantation Based on Microvascular Function in STEMI (SALVAGE)

ST Elevation Myocardial Infarction | Microcirculatory Perfusion

China
Technical University of Munich

Unknown

Extracorporeal Perfusion of Microvascular Free Flaps

Perfusion | Complication of Perfusion

Germany
The University of Hong Kong
Queen Mary Hospital, Hong Kong; Ruttonjee Hospital, Hong Kong

Completed

Endovascular Therapy in Acute Ischaemic Stroke Due to Large Vessel Occlusion

Acute Ischaemic Stroke

Hong Kong
NHS Greater Glasgow and Clyde
King's College London; University of Edinburgh; University of Glasgow

Unknown

Penumbra and Recanalisation Acute Computed Tomography in Ischaemic Stroke Evaluation (PRACTISE)

Ischaemic Stroke

United Kingdom
BDH-Klinik Hessisch Oldendorf

Recruiting

Prognostic Factors to Regain Consciousness

Stroke | Traumatic Brain Injury | Neurologic Disorder | Disorder of Consciousness | Hypoxic-Ischemic Encephalopathy

Germany
Semmelweis University

Completed

Hypoxic-Ischemic Encephalopathy Therapy Optimization in Neonates for Better Neuroprotection With Inhalative CO2 (HENRIC)

Perinatal Asphyxia | Hypocapnia | Hypoxic-Ischaemic Encephalopathy

Hungary
National Institute of Cardiology, Warsaw, Poland

Completed

The Influence of Coronary Chronic Total Occlusion on Myocardial Perfusion on Computed Tomography (COPACABANA)

Myocardial Ischemia | Percutaneous Coronary Intervention | Coronary Occlusion | Myocardial Perfusion Imaging

Poland
Irmandade Santa Casa Misericórdia Marília

Completed

Vascular Closure Device Versus Transradial Approach in Primary Percutaneous Coronary Intervention (ARISE-2)

Myocardial Infarction | Injury of Radial Artery | Complications; Device, Vascular | Injury; Blood Vessel, Femoral, Artery

Brazil
The Hospital for Sick Children

Not yet recruiting

Early Virtual Intervention for Infants With CP Following HIE Diagnosis (RECOVER)

Cerebral Palsy | Brain Injuries | Hypoxic-Ischemic Encephalopathy | Perinatal Hypoxia

Canada
Universitätsklinikum Hamburg-Eppendorf

Completed

The Effect of Perioperative Cardiac Output-guided GDT on Oxygen Delivery, Consumption, and Microcirculatory Perfusion (CUSTOM)

Oxygen Consumption | Postoperative Acute Kidney Injury | Major Non-cardiac Surgery | Oxygen Delivery | Microcirculatory Perfusion | Caridac Output-guided Goal-directed Hemodynamic Therapy | Postoperative Acute Myocardial Injury

Germany

Clinical Trials on Ischemia-reperfusion Injury

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