Clinical Trials on Ischemic White Matter Disease

Total 14679 results

Baycrest
Sunnybrook Health Sciences Centre

Unknown

Cognitive Changes and Rehabilitation in People With Transient Ischemic Attack, Stroke, or Stroke Risk Factors

Transient Ischemic Attack | Mild Stroke | Ischemic White Matter Disease | Stroke Risk

Canada
Wei Wang

Unknown

MRI,Gene And Cognitive Performance Study of Patients With Cerebral White Matter Lesions(WMLs)

Cerebral White Matter Lesions

China
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Assessment of the Impact of Gadolinium Injection on the Measurement of the QSM Signal (GADO-QSM)

White Matter Disease

France
Virginia Commonwealth University
Foundation for Physical Therapy, Inc.; Children's Hospital Foundation

Completed

Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention (SPEEDI)

Infant, Premature, Diseases | Brain White Matter Disease Periventricular

United States
Children's Hospital Medical Center, Cincinnati
The Gerber Foundation

Completed

Protein Supplementation in Infants With Brain Injury

Perinatal Stroke | White Matter Injury | Hypoxic-ischemic Encephalopathy

United States
Wake Forest University Health Sciences
National Institute on Aging (NIA)

Completed

Brain Networks and Mobility Function: B-NET (B-NET)

Central Nervous System | White Matter Disease

United States
National Cheng-Kung University Hospital

Recruiting

Assessment of Motor Adaptation in Precision Grip Performance of Children

Hand Strength, Child, Sensation, White Matter

Taiwan
Calico Life Sciences LLC
AbbVie

Recruiting

An Open-Label Exploratory Study of ABBV-CLS-7262 Subjects With Vanishing White Matter Disease

Vanishing White Matter Disease

United States, Netherlands
Shengjing Hospital

Unknown

Brain White Matter Injury in Late Preterm Infants

White Matter Injury

China
Dr. Sandra E Black

Recruiting

Amyloid and Glucose PET Imaging in Alzheimer and Vascular Cognitive Impairment Patients With Significant White Matter Disease (MITNEC C6)

Alzheimer's Disease | Vascular Cognitive Impairment | Small Vessel Disease White Matter Hyperintensities Subtype

Canada
Chinese University of Hong Kong

Recruiting

Use of Gou-Teng to Treat Patients With Mild Cognitive Impairment

Mild Cognitive Impairment | White Matter Hyperintensity

Hong Kong
Centre Hospitalier Universitaire, Amiens

Recruiting

Impact of Cerebral Ventricular Dilatations and Cerebrospinal Fluid Pulsations on Periventricular White Matter in Hydrocephalic Patients (HYDRODIFF)

Hydrocephalus | Cerebrospinal Fluid | Cerebral Ventricle | White Matter Fiber

France
IRCCS Eugenio Medea

Active, not recruiting

Evaluation of Brain Waste Clearance Pathways Using Magnetic Resonance Imaging in Pediatric Patients With White Matter Diseases

Pediatric Disorder | Glymphatic System | White Matter Disease | Perivascular Disease

Italy
Akira Sekikawa
National Institute on Aging (NIA)

Recruiting

Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers (ACE)

Cognitive Decline | Arterial Stiffness | White Matter Lesions

United States
University of Pittsburgh

Recruiting

MR Imaging of Perinatal Brain Injury

Perinatal White Matter Brain Injury

United States
Hadassah Medical Organization

Withdrawn

VEGF as a Prognostic Factor for White Matter Damage in Preterm Infants

Preterm Infants With White Matter Damage | Preterm Infants Developing Normally
The First Hospital of Jilin University
National Natural Science Foundation of China

Unknown

The Relationship Between Right-to-left Shunt and Brain White Matter Lesions in Patients With Migraine (CAMBRAIN)

Migraine Disorders | White Matter Disease | Right-to-left Shunt

China
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Evaluation of the Reproducibility of the Measurement of the QSM Signal (Quantitative Susceptibility Mapping) (ERESI)

Multiple Sclerosis | White Matter Hyperintensity

France
Augusta University
Georgia Rehabilitation Institute

Recruiting

Chronic Remote Ischemic Conditioning in Vascular Cognitive Impairment: A Dose Escalation Study

Cognition Disorder | Age-related Cerebral White Matter Changes

United States
Centre Hospitalier Universitaire de Nice

Recruiting

Diagnostic Value of eVOG (DIVEyes)

Multiple Sclerosis | Radiologically Isolated Syndrome | White Matter Lesions

France
AstraZeneca

Completed

THALES - Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death (THALES)

Acute Ischaemic Stroke | Transient Ischaemic Attack

Belgium, France, Italy, Spain, Sweden, Thailand, Germany, Korea, Republic of, Brazil, Hungary, India, Mexico, Vietnam, China, Taiwan, Hong Kong, Slovakia, Australia, Poland, Saudi Arabia, Ukraine, Canada, Russian Federation, Bulgaria, R... and more
AstraZeneca

Completed

[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES] (SOCRATES)

Acute Ischaemic Stroke | Transient Ischaemic Attack

Sweden, United States, Australia, Brazil, Bulgaria, France, Italy, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Turkey, Vietnam, Germany, Philippines, China, Hungary, Romania, Ukraine, Hong Kong, Argentina, Bel... and more
St. Luke's Hospital, Chesterfield, Missouri
Washington University School of Medicine

Terminated

Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease (HBO)

Encephalopathy | Impaired Oxygen Delivery | White Matter Hyperintensities

United States
Columbia University
National Institute on Aging (NIA)

Completed

Brain Vascular Disease in Aging and Dementia

Dementia | Alzheimer Disease | Aging | White Matter Hyperintensities

United States
University of Alabama at Birmingham
Troy University

Completed

Use of Automated Office Blood Pressure Monitoring

Hypertension | Hypertension, Resistant to Conventional Therapy | Uncontrolled Hypertension | Hypertension, White Coat

United States
Bayer

Completed

Study to Gather Information to What Extent Patients Follow the Treatment Regimen of Low-dose Aspirin for Primary and Secondary Prevention of Diseases of the Heart and Blood Vessels (PALACE)

Myocardial Infarction | Unstable Angina | Angina | Ischaemic Heart Disease | Stroke (Including Ischaemic Stroke and Transient Ischaemic Attack)

Germany, United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust; The Stroke Association, United Kingdom

Completed

Psychoeducation for Transient Ischaemic Attack and Minor Stroke (OPTIMISM)

Stroke | Transient Ischaemic Attack

United Kingdom
IRCCS Policlinico S. Donato

Completed

White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study

Congenital Heart Disease | Aging, Premature | White Matter Hyperintensities

Italy
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion in Man - A Bradykinin Dependent Pathway

Ischaemic Heart Diseases

United Kingdom
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-reperfusion on the Endogenous Fibrinolysis in Man

Ischaemic Heart Diseases

United Kingdom
West China Hospital
National Natural Science Foundation of China; Chengdu University of Traditional... and other collaborators

Completed

Cohort Study for Severe Ischaemic Stroke (SIS)

Severe Ischaemic Stroke | Malignant Ischaemic Stroke

China
Hospital de Clinicas de Porto Alegre

Completed

Hemodynamic Responses of Stable Ischemic Heart Disease Patients to a Comedy Session

Ischaemic Heart Disease

Brazil
Aarhus University Hospital Skejby
Abbott

Active, not recruiting

The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER) (OCTOBER)

Ischemic Heart Disease | Ischaemic Heart Disease

Denmark, United Kingdom, Sweden, Finland, Germany, Belgium, Norway, Poland, Netherlands, Estonia, Ireland, Italy, Latvia
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion and Remote Ischaemic Preconditioning in Man - A Bradykinin Dependent Pathway

Ischaemic Heart Diseases

United Kingdom
University of Edinburgh
University of Aarhus; University of Oxford

Completed

The Effect of Ischaemic-Reperfusion and Ischaemic Preconditioning on the Endogenous Fibrinolysis in Man

Ischaemic Heart Diseases

United Kingdom
Assistance Publique - Hôpitaux de Paris

Terminated

Therapeutic Effects of Maternal Melatonin Administration on Brain Injury and White Matter Disease (PREMELIP)

Premature Birth

France
Assistance Publique Hopitaux De Marseille

Recruiting

Neonatal Hypoxic Ischemic Encephalopathy : Safety and Feasibility Study of a Curative Treatment With Autologous Cord Blood Stem Cells (NEOSTEM)

Neonatal Hypoxic-ischaemic Encephalopathy

France
Tel-Aviv Sourasky Medical Center

Unknown

White Matter Pathology in Parkinson's Disease (PD)

White Matter Lesions | Postural Instability Gait Disorders

Israel
University Children's Hospital, Zurich

Completed

Correlation of Risk Factors and Severity of Hypoxic-ischaemic Encephalopathy

Hypoxic Ischaemic Encephalopathy

Switzerland
UNC Lineberger Comprehensive Cancer Center

Recruiting

MRI Biomarkers for Radiation-Induced Neurocognitive Decline Following SRS of Newly Diagnosed Brain Mets

Neurocognitive Deficit | Brain Metastases | Radiation Exposure | White Matter Alterations

United States
University College Cork
Karolinska Institutet

Completed

BiHiVE2 Study. The Investigation and Validation of Predictive Biomarkers in Hypoxic-ischaemic Encephalopathy. (BiHiVE2)

Asphyxia | Hypoxic Ischaemic Encephalopathy (HIE)

Sweden, Ireland
Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

A Research Study To Test How Multiple Doses Of Filgrastim Hospira Works In The Body Of Healthy Study Subjects When Given by Subcutaneous Injection (SC) (Shot) Compared To An Already U.S.-Approved Drug Neupogen® (Amgen)

Neutropenia (Low White Blood Cell Count)

United States
Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

A Research Study To Test How Filgrastim Hospira Works In The Body Of Healthy Study Subjects When Given By Subcutaneous Injection (Shot) Compared To An Already U.S.-Approved Drug Neupogen® (Amgen)

Neutropenia (Low White Blood Cell Count)

United States
Ottawa Heart Institute Research Corporation
The Ottawa Hospital

Terminated

Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease

Stroke | Carotid Artery Stenosis | TIA

Canada
Li Haiyan

Unknown

Diagnosis and Treatment of Minor Ischaemic Stroke According to the Etiology and Pathogenesis

Ischaemic Stroke

China
Fundación Pública Andaluza para la Investigación...

Unknown

Homebased Monitoring Cardiac Rehabilitation Program (NUUBO)

Homebased Cardiac Rehabilitation Program After Ischemic Heart Disease

Spain
Prehospital Center, Region Zealand

Active, not recruiting

Using Machine Learning to Optimise the Danish Drowning Formula (DROWN_DDF2)

Drowning | Drowning, Near | Drowning; Asphyxia | Drowning and Nonfatal Submersion | Drowning and Submersion While in Bath-Tub | Drowning and Submersion While in Natural Water | Drowning and Submersion Due to Fall Off Ship | Drowning and Submersion While in Swimming-Pool

Denmark
King Abdulaziz University

Unknown

Effect of Light Curable Resin Modified Glass Ionomer Varnish on Non-Cavitated Proximal Carious Lesions' Progression

Dental Caries | Dental White Spot

Saudi Arabia
The University of Hong Kong
Queen Mary Hospital, Hong Kong; Ruttonjee Hospital, Hong Kong

Completed

Endovascular Therapy in Acute Ischaemic Stroke Due to Large Vessel Occlusion

Acute Ischaemic Stroke

Hong Kong
NHS Greater Glasgow and Clyde
King's College London; University of Edinburgh; University of Glasgow

Unknown

Penumbra and Recanalisation Acute Computed Tomography in Ischaemic Stroke Evaluation (PRACTISE)

Ischaemic Stroke

United Kingdom

Clinical Trials on Ischemic White Matter Disease

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