Clinical Trials on Late-onset Retinal Degeneration

Total 2619 results

OcuTerra Therapeutics, Inc.

Completed

Safety and Exploratory Efficacy Study of SF0166 in the Treatment of Neovascular Age-Related Macular Degeneration (AMD)

Age-Related Macular Degeneration

United States
AbbVie
AbbVie

Enrolling by invitation

Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy (RGX-314 SRLTFU)

Wet Macular Degeneration | Neovascular Age-related Macular Degeneration

United States
Semmelweis University

Completed

Seven-year Outcomes Following Intensive Anti-VEGF Therapy in Wet AMD

Age-Related Macular Degeneration

Hungary
Alkahest, Inc.

Completed

A Study to Assess the Efficacy and Safety of AKST4290 With Aflibercept in Patients With Newly Diagnosed nAMD (PHTHALO-205)

Neovascular Age-related Macular Degeneration

United States, Germany, Poland, Hungary
Institute of Biophysics and Cell Engineering of...
Belarusian State Medical University

Enrolling by invitation

Treatment of Age-related Macular Degeneration Using Retinal Stem and Progenitor Cells

Age-Related Macular Degeneration

Belarus
Samsung Bioepis Co., Ltd.

Completed

A Study to Compare SB11 (Proposed Ranibizumab Biosimilar) to Lucentis in Subjects With Neovascular Age-related Macular Degeneration (AMD)

Age-Related Macular Degeneration

Korea, Republic of, United States, India, Germany, Hungary, United Kingdom, Czechia, Poland, Russian Federation
King's College Hospital NHS Trust
King's College London

Completed

A Pharmacokinetic Study: Ranibizumab, Aflibercept and the Effect of Vitrectomy. (VITCLEAR)

Age Related Macular Degeneration

United Kingdom
Stealth BioTherapeutics Inc.

Completed

An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States
Wills Eye
Mid Atlantic Retina

Completed

Dorzolamide-timolol in Combination With Anti-vascular Endothelial Growth Factor Injections for Wet Age-related Macular Degeneration (DAWN)

Wet Macular Degeneration | Neovascular Age-related Macular Degeneration

United States
Second Sight Medical Products

Completed

Argus II Retinal Prosthesis System Dry AMD Feasibility Study Protocol

Age Related Macular Degeneration

United Kingdom
AnewPharma
West China Hospital

Suspended

Phase 1 Study of CM082 in Patients With wAMD

Age-Related Macular Degeneration

China
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab 0.5 mg Administered as Two Alternative Dosing Regimens in Chinese Patients With nAMD (Age Related Macular Degeneration) (DRAGON)

Neovascular Age-related Macular Degeneration

China
University of California, San Diego
Genentech, Inc.

Completed

Study EvAluating Genotypes While Using Lucentis 2 (SEAGUL2)

Age-Related Macular Degeneration

United States
Duke University
National Institute on Aging (NIA)

Completed

Brain Connectivity in Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States
University Health Network, Toronto

Completed

Intraocular Cytokines in Non-responders to Ranibizumab Treatment for Neovascular AMD

Age Related Macular Degeneration

Canada
Moorfields Eye Hospital NHS Foundation Trust

Completed

VITAL - Individualising Therapy for Neovascular AMD With Aflibercept (VITAL)

Age Related Macular Degeneration

United Kingdom
Associated Retinal Consultants, Michigan
Genentech, Inc.

Completed

Genetic Analysis of Patients Responsive to Ranibizumab But Resistant to Aflibercept

Age-Related Macular Degeneration

United States
Association for Innovation and Biomedical Research...

Completed

Epidemiological Study of the Prevalence of Age-Related Macular Degeneration in Portugal

Age-Related Macular Degeneration

Portugal
Bayer

Terminated

Regorafenib Eye Drops: Investigation of Efficacy and Safety in Neovascular Age Related Macular Degeneration (DREAM)

Macular Degeneration

Hong Kong, Korea, Republic of, United States, Canada, Switzerland, Spain, Japan, Italy, Czech Republic, Australia, Austria, Slovakia, Germany, Hungary, Israel, Chile, France, Colombia
Alcon Research

Completed

First-in-Human Study of LHA510 in Elderly Subjects and Patients With Age-Related Macular Degeneration

Age-Related Macular Degeneration
Jeffrey S Heier
Regeneron Pharmaceuticals

Unknown

IAI Versus Sham as Prophylaxis Against Conversion to Neovascular AMD (PRO-CON)

Age-Related Macular Degeneration

United States
David M. Brown, M.D.
Novartis Pharmaceuticals

Terminated

Lucentis Utilizing Visudyne (LUV Trial) Combination Therapy in the Treatment of Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States
Thomas Jefferson University
Johns Hopkins University; Dartmouth-Hitchcock Medical Center

Completed

Improving Function in Age-Related Macular Degeneration (IF-AMD)

Age-Related Macular Degeneration

United States
East Florida Eye Institute
Genentech, Inc.

Unknown

Comparison of Pharmacokinetics of and Effect on Systemic VEGF Levels in Age Related Macular Degeneration Patients

Age Related Macular Degeneration

United States
Regeneron Pharmaceuticals
Bayer

Completed

Open-label Extension Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Neovascular ("Wet") Age-related Macular Degeneration (AMD)

Neovascular Age-related Macular Degeneration

United States, Canada
Medical University of Vienna

Completed

Effects of Lutein Supplementation on Macular Pigment Optical Density and Visual Acuity in Patients With Age-related Macular Degeneration

Age-Related Macular Degeneration

Austria
Alcon Research

Completed

WALTZ - Wet Age-Related Macular Degeneration (AMD) AL-39324 Treatment Examination

Age Related Macular Degeneration
Genentech, Inc.

Completed

Extension Study of rhuFab V2 in Subjects With Neovascular Age-Related Macular Degeneration (AMD)

Macular Degeneration
Al-Azhar University
Hassan , Hosny , M.D. M.Sc; Samour , Hany M.D. M.Sc; Ismail , Mahmoud M.D. M.Sc; Higazy , Hasan M.D. M.Sc and other collaborators

Unknown

Safety Study of Use of Autologous Bone Marrow Derived Stem Cell in Treatment of Age Related Macular Degeneration

Age Related Macular Degeneration

Egypt
Notal Vision Ltd.

Completed

Foresee Home for Monitoring Age Related Macular Degeneration (AMD) (Foresee Home)

Age Related Macular Degeneration

Israel
Ziv Hospital

Unknown

Plaqenil Role in Prevention of Age Related Macular Degeneration

Age Related Macular Degeneration

Israel
University of Roma La Sapienza

Completed

MP-1 Biofeedback: Pattern Stimulus Versus Audio-feedback in AMD

Age Related Macular Degeneration

Italy
The Ludwig Boltzmann Institute of Retinology and...
Medical University of Graz; Medical University of Vienna; Medical University... and other collaborators

Unknown

Manta Study: Avastin Versus Lucentis in Age Related Macular Degeneration (MANTA)

Age Related Macular Degeneration

Austria
MacuCLEAR, Inc.

Completed

A Pilot Study of the Safety of MC-1101 in Both Normal Volunteers and Patients With Early Dry AMD

Age-Related Macular Degeneration

United States
Centre de Recherche en Nutrition Humaine Rhone-Alpe

Completed

Superoxide Dismutase (SOD) as Antioxidant Treatment OF Age Related Macular Degeneration (ARMD)

Age Related Macular Degeneration

France
The Ludwig Boltzmann Institute of Retinology and...

Completed

Transplantation of Autologous RPE Versus Translocation of Autologous RPE and Choroid in AMD

Age-Related Macular Degeneration

Austria
Rudolf Foundation Clinic

Unknown

Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population

Age-Related Macular Degeneration

Austria
Eyetech Pharmaceuticals
Pfizer

Terminated

Macugen (Pegaptanib Sodium) Alone, Versus Macugen in Combination With PDT (Photodynamic Therapy) With Visudyne (Verteporfin) in Patients With Age-Related Macular Degeneration (AMD)

Age-Related Macular Degeneration

United States
Eyetech Pharmaceuticals
Pfizer

Completed

Study of the Safety, Tolerability and Pharmacokinetics of 1 Mg/Eye and 3 Mg/Eye Pegaptanib Sodium in Patients With Exudative Age-Related Macular Degeneration (AMD)

Age-Related Macular Degeneration
Hospital St. Joseph, Marseille, France

Unknown

The Evolution of Visual Acuity Measured by Electronic Tablet / Computer of Exudative AMD Patients

Macular Degeneration Exudative Eye Bilateral

France
Tel Aviv Medical Center

Completed

Pars Plana Vitrecromy in Patients Aged 85 Years and Above (PPV)

Age Related Macular Degeneration | Retinal Detachment | Vitreous Injury
Moorfields Eye Hospital NHS Foundation Trust
King's College London; Cardiff University; University College, London; Newcastle... and other collaborators

Recruiting

Quality-Assured Follow-up of Quiescent Neovascular Age -Related maculaR dEgeneration by Non-medical Practitioners (FENETRE)

AMD

United Kingdom
Novartis Pharmaceuticals

Completed

Safety and Tolerability of Ranibizumab in Mono/Bilateral Wet Age Related Macular Degeneration (w-AMD) Patients in Eyes With BCVA<2/10 and/or 2nd Affected Eye (TWEYES)

Wet Age Related Macular Degeneration

Italy
Changhua Christian Hospital

Completed

Real World Outcomes of Intravitreal Anti-vascular Endothelial Growth Factors for Neovascular Age Related Macular Degeneration in Taiwan (OIVAEGFFAMDIT)

AMD

Taiwan
Regeneron Pharmaceuticals

Completed

Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection) (RE-VIEW)

Age - Related Macular Degeneration (AMD)

United States
Klinikum Bremen-Mitte, gGmbH
Kompetenzzentrum für Klinische Studien, Bremen

Unknown

Prevention of Vision Loss in Patients With Age-Related Macular Degeneration (AMD) by Intravitreal Injection of Bevacizumab and Ranibizumab (VIBERA)

Age-Related Neovascular Macular Degeneration

Germany
Beijing Tongren Hospital

Recruiting

Safety and Efficacy of Autologous Transplantation of iPSC-RPE in the Treatment of Macular Degeneration

Macular Degeneration

China
Hoffmann-La Roche

Recruiting

Study of Zifibancimig in Participants With Neovascular Age-Related Macular Degeneration (BURGUNDY)

Macular Degeneration

United States
University Hospital, Bordeaux
University of Bordeaux

Withdrawn

MacuTest Website for Personalized AMD Risk Prediction and Prevention (MACUTEST)

Macular Degeneration

France
Bayer
Regeneron Pharmaceuticals

Completed

Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye (ARIES)

Macular Degeneration

Spain, Hungary, United Kingdom, Australia, Italy, Canada, France, Germany

Clinical Trials on Late-onset Retinal Degeneration

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