Clinical Trials on Limb Deformities, Congenital in Singapore

Total 46 results

Tan Tock Seng Hospital

Completed

Effectiveness of Specifically Optimized Off-the-counter Foot Orthosis for the Subtle Cavus Foot

Plantar Fasciitis | Achilles Tendinopathy | Insertional Achilles Tendinopathy | Metatarsalgia | Pes Cavus | Subtle Cavus Foot | Mechanical Foot Pains | Strain of Peroneal Tendon | Pes Cavus, Bilateral | Pes Cavovarus

Singapore
National Heart Centre Singapore

Unknown

Generation of Marfan Syndrome and Fontan Cardiovascular Models Using Patient-specific Induced Pluripotent Stem Cells

Marfan's Syndrome

Singapore
Singapore General Hospital
Diana Chan Xin Hui; Lin Xufeng; Yap Haoyun

Recruiting

Incidence and Factors Affecting the Development and Outcome of Phantom Limb Pain (PLP) - A Single-centre Prospective Cohort Study.

Phantom Limb Pain

Singapore
Changi General Hospital

Completed

Drug Impregnated Bioabsorbable Stent in Asian Population Extremity Arterial Revascularization (DISAPEAR Study) (DISAPEAR)

Critical Limb Ischemia

Singapore
Singapore General Hospital

Completed

Investigating the Safety and Efficacy of the Treatment With the Selution Sirolimus Coated Balloon in TASC C and D Tibial Occlusive Disease in Patients With Critical Limb Ischemia From Singapore (PRESTIGE)

Critical Limb Ischemia

Singapore
Singapore General Hospital

Completed

Investigating the Safety and Efficacy of the Treatment With Luminor DCB and Angiolite DES of iVascular in TASC C and D Tibial Occlusive Disease in Patients With Critical Limb Ischemia (MERLION)

Critical Limb Ischemia

Singapore
National University of Singapore

Completed

Tele-Rehabilitation Pilot Evaluation Study

Stroke | Pneumonia | Fractures, Bone | Fall | Lower Limb Amputation | Deconditioning | Lower Limb Joint Replacement (Hip or Knee) | Musculoskeletal Conditions (e.g., Tendinitis, Capsulitis)

Singapore
National Heart Centre Singapore

Unknown

Study of RV Remodeling in Congenital Heart Disease (RVShape)

Congenital Heart Disease

Singapore
Singapore General Hospital

Recruiting

Evaluation of Post-Angioplasty Outcomes

Peripheral Arterial Disease | Critical Limb Ischemia

Singapore
National Heart Centre Singapore
Ministry of Health, Singapore

Unknown

Integrated Computational modelIng of Right Heart Mechanics and Blood Flow Dynamics in Congenital Heart Disease

Pulmonary Hypertension | Congenital Heart Disease

Singapore
Singapore General Hospital
National University Hospital, Singapore

Unknown

Investigating the Safety and Efficacy of the Treatment With the Non-compliant Jade Balloon in TASC C and D Athero-occlusive Infra-inguinal Disease in Patients With Chronic Limb Threatening Limb Ischemia From SingaporE (PINNACLE)

Peripheral Artery Disease | Critical Limb Ischemia

Singapore
KK Women's and Children's Hospital
Covidien Private Limited

Completed

Near Infrared Spectroscopy in Cyanotic Congenital Heart Disease

Congenital Heart Defects

Singapore
Singapore General Hospital

Active, not recruiting

Prospective Registry to Investigate the Safety and Efficacy of the Treatment With the Selution Sirolimus Drug Coated Balloon in TASC C and D Atheroma-occlusive Infra-Inguinal Disease in Patients With Chronic Limb Threatening Ischemia From Singapore (PRISTINE)

Peripheral Artery Disease | Critical Lower Limb Ischemia

Singapore
KK Women's and Children's Hospital
National University Hospital, Singapore; Cumberland Pharmaceuticals

Withdrawn

Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature Babies

Ductus Arteriosus, Patent | Very Low Birth Weight Infants

Singapore
Singapore General Hospital

Completed

Review of Anaesthetic Practice in Orthognathic Surgery

Blood Pressure | Maxillofacial Abnormalities | Anesthesia

Singapore
National Human Genome Research Institute (NHGRI)

Completed

Perceptions of Thalassemia Major in Singapore: An Exploratory Study of Stigma

Thalassemia Major

Singapore
Singapore General Hospital

Active, not recruiting

Intervention With Selution SLR™ Agent Balloon for Endovascular Latent Limus Therapy for Failing AV Fistulas (ISABELLA) Trial (ISABELLA)

Arteriovenous Fistula | Dialysis Access Malfunction

Singapore
Singapore General Hospital

Recruiting

A Real-world Registry Investigating Sirolimus-coated Balloon Versus Paclitaxel-coated Balloon Angioplasty for the Treatment of Dysfunctional Arteriovenous Fistula (SAVE AVF)

Stenosis | Dialysis Access Malfunction

Singapore
LimFlow SA

Active, not recruiting

PROMISE International

Critical Limb Ischemia

New Zealand, Singapore, Netherlands, Germany, Austria
Singapore General Hospital
Boston Scientific Corporation

Completed

Recurrent Stenoses in Arteriovenous Fistula (AVF) for Dialysis Access: CuttIng ballooN angioplaSTy Combined wITh Paclitaxel drUg coaTed Balloon Angioplasty, an observatIONal Clinical Study (INSTITUTION)

Dialysis Access Malfunction

Singapore
Changi General Hospital

Completed

Prospective Study Assessing Blood Pressure and Other Outcomes Post-treatment in Patients With Primary Aldosteronism (PA_PACES)

Primary Aldosteronism | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Completed

COmbiNing Cutting and Drug-Eluting Balloon for Resistant Arteriovenous Fistula sTenOsis (CONCERTO) (CONCERTO)

Arteriovenous Fistula Stenosis

Singapore
National University Hospital, Singapore

Active, not recruiting

Does an Educational Video for Aneuploidy Screening Improve Informed Choice Among Pregnant Women? (EVA)

Down Syndrome | Aneuploidy | Pregnancy Early

Singapore
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Recruiting

Sirolimus Drug-coated Balloon Versus Stent Graft (SUSTAIN)

Blood Vessel Prosthesis | Arteriovenous Shunt Thrombosis

Singapore
Singapore General Hospital

Unknown

Use of Implanting the Biotronik Passeo-18 Lux Drug Coated Balloon to Treat Failing Haemodialysis Arteriovenous Fistulas and Grafts. (SEMPER FI)

Hemodialysis Access Failure | Dialysis Access Malfunction | Arterio-venous Fistula | Arteriovenous Graft Stenosis

Singapore
Ipsen

Completed

Study to Assess Impact of Dysport Injections Early After Stroke on Upper Limb Spasticity Progression (ONTIME Pilot)

Stroke | Upper Limb Spasticity

Malaysia, Philippines, Singapore, Thailand
Changi General Hospital
Singapore General Hospital

Recruiting

Outcome of Patients With Primary Aldosteronism (PA_Outcome)

Primary Aldosteronism | Hypokalemia | Chronic Renal Disease | Cardiovascular Morbidity | Mineralocorticoid Excess | Adrenalectomy; Status | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral) | Mineralocorticoid Antagonists [Aldosterone...

Singapore
Singapore General Hospital

Recruiting

Effect of Pre-operative Forearm Exercises on Arterial Venous Fistula Maturation and Blood Flow

End Stage Renal Disease | Arteriovenous Fistula

Singapore
Changi General Hospital

Completed

A Randomised Trial Comparing Supraclavicular Block vs Supraclavicular and Pecs II Block in Arteriovenous Grafting

Kidney Failure, Chronic | Arteriovenous Fistula | Arteriovenous Graft | Renal Failure, End-stage

Singapore
Singapore General Hospital
Shanghai Yueyang Integrated Medicine Hospital; Singapore Bao Zhong Tang TCM...

Completed

Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders

Myelodysplastic Syndrome (MDS) | Myelofibrosis (MF) | Thalassemia Intermedia | Aplastic Anaemia (AA)

Singapore
Singapore General Hospital

Completed

MAgicTouch™ Intervention Leap for Dialysis Access (MATILDA) Trial (MATILDA)

End Stage Renal Disease | End Stage Renal Failure on Dialysis | Stenosis | Dialysis Access Malfunction | Fistulas Arteriovenous

Singapore
Abbott Medical Devices

Active, not recruiting

LIFE-BTK Randomized Controlled Trial (LIFE-BTK)

Critical Limb Ischemia (CLI)

United States, Hong Kong, Australia, New Zealand, Singapore, Taiwan
MedAlliance, LLC
NAMSA

Recruiting

SELUTION4BTK Trial

Peripheral Arterial Disease | Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities

United States, Switzerland, New Zealand, Singapore, Hong Kong, Netherlands, France, Germany, Austria, Italy
Sanofi
Bristol-Myers Squibb

Completed

Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt Palliation (CLARINET)

Heart Defects, Congenital

France, Canada, Brazil, Poland, Russian Federation, Germany, Italy, Netherlands, Portugal, Spain, Sweden, India, Malaysia, Singapore, Taiwan, Belgium, Mexico, Argentina, Denmark, Egypt, Finland, Hungary, Israel, Norway, Korea, Republic of, Hong Kong and more
Mirum Pharmaceuticals, Inc.

Completed

Evaluation of Maralixibat in Biliary Atresia Response Post-Kasai (EMBARK)

Biliary Atresia

United States, United Kingdom, China, Taiwan, Germany, Poland, Singapore, Vietnam
National Hospital Organization Nagoya Medical Center

Recruiting

ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016

Acute Lymphoblastic Leukemia | Down Syndrome | Childhood Cancer

Taiwan, Thailand, Hong Kong, Singapore, Malaysia, Japan
Merck KGaA, Darmstadt, Germany

Completed

Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®

Growth Hormone Deficiency | Turner Syndrome

Argentina, Australia, Austria, Canada, France, Germany, Italy, Norway, Russian Federation, Singapore, Spain, Sweden, United Kingdom
C. R. Bard

Completed

Lutonix® Global AV Registry Investigating Lutonix Drug Coated Balloon for Treatment of Native and Synthetic AV Fistulae (AVR)

Arteriovenous Fistula

United Kingdom, Singapore, France, Italy, Germany, Switzerland, Greece, Austria, Poland, Portugal, Saudi Arabia, Taiwan, Turkey
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia (RADICHOL 1)

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Taiwan, Brazil, Canada, South Africa, United Kingdom, Singapore
Novartis Pharmaceuticals

Completed

A Dose Escalation/Expansion Study of LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase

Tumors Characterized by Genetic Abnormalities of ALK

Australia, Belgium, Germany, Netherlands, Spain, Italy, Singapore, Korea, Republic of, United Kingdom, United States, Canada
Hoffmann-La Roche

Completed

A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)

Down Syndrome

United States, Spain, Canada, New Zealand, Argentina, Mexico, Singapore
Hoffmann-La Roche

Completed

A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)

Down Syndrome

United States, Italy, Argentina, France, Spain, Mexico, Canada, New Zealand, Singapore, United Kingdom
Amryt Research Limited

Completed

Phase III Efficacy and Safety Study of Oleogel-S10 in Epidermolysis Bullosa (EASE)

Epidermolysis Bullosa

United States, Spain, Israel, Australia, France, Denmark, Switzerland, Italy, Hong Kong, Argentina, Austria, Brazil, Chile, Colombia, Czechia, Georgia, Germany, Greece, Hungary, Ireland, Romania, Russian Federation, Serbia, Singapore, U... and more
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Canada, Brazil, Taiwan, Singapore, South Africa, United Kingdom
Merck Sharp & Dohme LLC

Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Von Hippel-Lindau Disease | Pancreatic Neuroendocrine Tumor | Pheochromocytoma/Paraganglioma | Advanced Gastrointestinal Stromal Tumor | HIF-2α Mutated Cancers

Canada, United States, Denmark, France, Germany, Hungary, Italy, Russian Federation, Spain, Sweden, Turkey, Israel, United Kingdom, Netherlands, Australia, China, Singapore, Japan
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore

Clinical Trials on Limb Deformities, Congenital in Singapore

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