Clinical Trials on Lumbar Disc Degeneration

Total 5296 results

  • First Affiliated Hospital of Fujian Medical University
    Recruiting
    Treatment of Transcranial Alternating Current Stimulation（tACS）on Cerebellar Ataxia
    Spinocerebellar Ataxia Type 3 | Multiple System Atrophy-cerebellar Type
    China
  • InSightec
    Active, not recruiting
    ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders
    Parkinson's Disease | Movement Disorders | Tardive Dyskinesia | Dystonia | Essential Tremor | Huntington's Disease | Wilson's Disease | Holmes Tremor | Orofacial Dyskinesias
    Canada
  • McMaster University
    Joseph Brant Hospital
    Completed
    The Effects of Whole-body Exercise to Improve Swallowing Function in Older Adults With Dementia
    Parkinson Disease | Cough | Neuro-Degenerative Disease | Swallowing Disorder | Old Age; Dementia
    Canada
  • University Hospitals Coventry and Warwickshire...
    Recruiting
    Volume Mode Non-invasive Ventilation in Amyotrophic Lateral Sclerosis
    Nervous System Diseases | Neuromuscular Diseases | Respiratory Failure | Respiratory Insufficiency | Amyotrophic Lateral Sclerosis | Sleep-Disordered Breathing | Neuro-Degenerative Disease | Neuron Disease, Motor
    United Kingdom
  • University of Pittsburgh
    Recruiting
    Longitudinal Study of Neurodegenerative Disorders
    Lysosomal Storage Diseases | Leukodystrophy | Niemann-Pick Diseases | Batten Disease | Gaucher Disease | Krabbe Disease | Alpha-Mannosidosis | Osteopetrosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | GM1 Gangliosidoses | MPS I | MPS II | Vanishing White Matter Disease | Multiple Sulfatase Deficiency... and other conditions
    United States
  • University of Rochester
    University of Colorado, Denver; Massachusetts General Hospital; Stanford University
    Recruiting
    Community Outreach for Palliative Engagement -- Parkinson Disease (COPE-PD)
    Parkinson Disease | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism | Dementia With Lewy Bodies | Vascular Parkinsonism | Parkinson Disease Dementia | Lewy Body Parkinsonism
    United States
  • Sheba Medical Center
    Enrolling by invitation
    Brain Network Activation in Patients With Movement Disorders (BNA-MDi)
    Parkinson Disease | Cerebellar Ataxia | Dystonia | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Essential Tremor | Dementia With Lewy Bodies | Normal Pressure Hydrocephalus
    Israel
  • Albert Einstein College of Medicine
    Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators
    Enrolling by invitation
    ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program (ScreenPlus)
    Mucopolysaccharidosis II | Fabry Disease | Niemann-Pick Disease, Type C | Mucopolysaccharidosis VI | Lysosomal Acid Lipase Deficiency | Metachromatic Leukodystrophy | Gaucher Disease | Cerebrotendinous Xanthomatosis | Mucopolysaccharidosis IV A | GM1 Gangliosidosis | Mucopolysaccharidosis VII | Acid Sphingomyelinase... and other conditions
    United States
  • Children's Hospital Los Angeles
    Completed
    Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
    Granuloma | Anemia | Thrombocytopenia | Neutropenia | Sickle Cell Disease | Thalassemia | Niemann-Pick Disease | Wiskott-Aldrich Syndrome | Osteopetrosis | Fucosidosis | Chediak Higashi Syndrome | Hurler Disease
    United States
  • Fairview University Medical Center
    Unknown
    Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
    Mucopolysaccharidosis I | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Metachromatic Leukodystrophy | Pulmonary Complications | Fucosidosis | Globoid Cell Leukodystrophy | Gaucher's Disease | Mannosidosis | I Cell Disease
    United States
  • Zimmer Biomet
    Recruiting
    Clinical Outcomes Study of the Nexel Total Elbow
    Post-traumatic Arthritis | Degenerative Arthritis | Elbow Joint Destruction | Post-traumatic Lesions | Ankylosed Joints | Advanced Rheumatoid Arthritis | Joint Instability or Loss of Motion | Acute Comminuted Articular Fracture of Elbow Joint Surfaces | Bone Loss Contributing to Elbow Instability | Bilateral...
    United States, Australia, Finland, France, Germany, Italy, Netherlands, United Kingdom
  • Capital Medical University
    Peking University First Hospital; The First Affiliated Hospital of Anhui Medical... and other collaborators
    Recruiting
    China Cognition and Aging Study (COAST)
    Alzheimer Disease, Late Onset | Mild Cognitive Impairment(MCI) | Familial Alzheimer Disease (FAD) | Vascular Dementia (VaD) | Normal Control | Non-Alzheimer Degenerative Dementia
    China
  • Physio-Assist
    University Hospital, Marseille; CEISO
    Terminated
    Evaluation of the Safety of the Medical Device Simeox® (SIMETOL)
    Cystic Fibrosis | Chronic Bronchitis | Chronic Obstructive Airway Disease | Broncho-degenerative Disease | Idiopathic Bronchiectasis | Ciliary Dyskinesia
    France
  • Beth Israel Deaconess Medical Center
    Recruiting
    Gait Analysis in Neurological Disease
    Parkinson's Disease | Parkinsonian Disorders | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Huntington Disease | Atypical Parkinson Disease | Gait, Frontal
    United States
  • Washington University School of Medicine
    Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators
    Completed
    Tracking Neurodegeneration in Early Wolfram Syndrome (TRACK)
    Diabetes Mellitus | Type 1 Diabetes | Diabetes Insipidus | Wolfram Syndrome
    United States
  • Talaris Therapeutics Inc.
    Duke University
    Terminated
    Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders
    Niemann-Pick Disease | Alpha-mannosidosis | Tay Sachs Disease | Sandhoff Disease | Metachromatic Leukodystrophy (MLD) | Hurler-Scheie Syndrome | Hurler Syndrome (MPS I) | Hunter Syndrome (MPS II) | Sanfilippo Syndrome (MPS III) | Krabbe Disease (Globoid Leukodystrophy) | Adrenoleukodystrophy (ALD and AMN) | Pelizaeus...
    United States
  • Capital Medical University
    Wangjing Hospital, China Academy of Chinese Medical Sciences; Bejing Fengtai...
    Recruiting
    Remote Ischemic Conditioning for Cerebral Amyloid Angiopathy-related Intracerebral Hemorrhage (RIC-CAAH)
    Cerebral Amyloid Angiopathy | Intracerebral Hemorrhage Lobar
    China
  • Fujian Cancer Hospital
    Not yet recruiting
    the Efficacy and Safety of Dalpiciclib Combined With Third-generation EGFR-TKI in Patients With EGFR Mutation and Meningial Metastasis in Non-small Cell Lung Cancer Progressing Through Third-generation TKI and Platinum-containing Two-drug Chemotherapy
    Non-small Cell Lung Cancer Confirmed by Histopathology or Cytology | The TNM (8th) Phase is IV | With EGFR Mutations | Meningeal Progression Occurred After Previous Platinum-containing Two-drug Chemotherapy and Third-generation EGFR-TKI Treatment | Male or Female | The Age of 18 Years Old or... and other conditions
  • Northwestern University
    National Cancer Institute (NCI); Vasgene Therapeutics, Inc
    Active, not recruiting
    sEphB4-HSA in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
    Progressive Disease | Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8 | PSA Progression | Metastatic Prostate Adenocarcinoma | Castration Levels of Testosterone | Prostate Carcinoma Metastatic in the Bone | Castration-Resistant Prostate Carcinoma Refractory to Second-Generation... and other conditions
    United States
  • LMU Klinikum
    Seventh Framework Programme; NBIA Alliance
    Recruiting
    TIRCON International NBIA Registry (TIRCON)
    Neurodegeneration With Brain Iron Accumulation (NBIA) | Pantothenate Kinase-associated Neurodegeneration (PKAN) | Aceruloplasminemia | Beta-Propeller Protein-Associated Neurodegeneration (BPAN) | Mitochondrial Membrane Protein Associated Neurodegeneration (MPAN) | Fatty Acid Hydroxylase-associated... and other conditions
    Canada, Czechia, Germany, Italy, Netherlands, Poland, Serbia, Spain
  • Washington University School of Medicine
    Enrolling by invitation
    I-Tracking Neurodegeneration in Early Wolfram Syndrome (I-TRACK)
    Wolfram Syndrome
    United States
  • Saccadous, Inc.
    Barrow Neurological Institute; Dignity Health
    Completed
    Complex Eye Movements in Parkinson's Disease and Related Movement Disorders
    Parkinson Disease | Parkinsonian Disorders | Corticobasal Degeneration | Progressive Supranuclear Palsy | Huntington Disease | Essential Tremor | Parkinson's Disease and Parkinsonism | Vascular Parkinsonism | Parkinsonian Syndrome | Multiple System Atrophy, Parkinson Variant
    United States
  • University of Colorado, Denver
    Recruiting
    Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)
    Hearing Loss | Smith-Lemli-Opitz Syndrome | Cone-Rod Dystrophy
    United States
  • Azienda Socio Sanitaria Territoriale degli Spedali...
    Completed
    Transcranial Alternating Current Stimulation (tACS) in Patients With Ataxia (SCAtACS)
    Ataxia | Multiple System Atrophy | Spinocerebellar Ataxias | Ataxia With Oculomotor Apraxia | CANVAS
    Italy
  • New York Medical College
    Completed
    Human Placental-Derived Stem Cell Transplantation (HPDSC)
    Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions
    United States
  • Azienda Socio Sanitaria Territoriale degli Spedali...
    Completed
    Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia (SCA02)
    Ataxia | Multiple System Atrophy | Spinocerebellar Ataxias | Spinocerebellar Ataxia 3 | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Ataxia With Oculomotor Apraxia | CANVAS
    Italy
  • Global Healthy Living Foundation
    University of Alabama at Birmingham
    Recruiting
    PatientSpot Formerly Known as ArthritisPower (GHLF)
    Heart Failure | Stroke | Epilepsy | Multiple Sclerosis | Obesity | Diabetes | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Peripheral Arterial Disease | Inflammatory Bowel Diseases | Amyotrophic Lateral Sclerosis | Psoriasis | Asthma | Muscular Dystrophy | Fibromyalgia | Alzheimer... and other conditions
    United States
  • Shaare Zedek Medical Center
    Completed
    Procalcitonin Level and Kinetics in Children With Bacterial Infections
    Bacterial Infections | Bacteremia | Cellulitis | Urinary Tract Infection | Meningitis | Osteomyelitis | Septic Arthritis | Mastoiditis | Lobar Pneumonia
    Israel
  • Michael Iv
    Completed
    Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS
    Brain Injury | Brain Cancer | Brain Tumors | Primary Brain Neoplasm | Ischemic Cerebrovascular Accident | Central Nervous System Degenerative Disorder | Central Nervous System Infectious Disorder | Central Nervous System Vascular Malformation | Hemorrhagic Cerebrovascular Accident
    United States
  • Sanko University
    Completed
    Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns (therapy)
    Preterm Birth | Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Mechanical Ventilation Complication | Chronic Liver Disease | Hyaline Membrane Disease | Premature | Oxygen Toxicity | Neonatal Respiratory Failure | Atelectasis Neonatal | Mechanical Ventilation Pressure High | Pneumonia Neonatal | Lobar...
    Turkey
  • Azienda Socio Sanitaria Territoriale degli Spedali...
    Completed
    Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia (CStDCSAtaxia)
    Cerebellar Ataxia | Multiple System Atrophy | Spinocerebellar Ataxias | Spinocerebellar Degenerations | Spinocerebellar Ataxia 3 | Friedreich Ataxia | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Ataxia, Spinocerebellar | Ataxia, Cerebellar | Ataxia With Oculomotor Apraxia
    Italy
  • M.D. Anderson Cancer Center
    Active, not recruiting
    Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer
    Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Small Cell Neuroendocrine Carcinoma | Metastatic Prostate Adenocarcinoma | Castration-Resistant...
    United States
  • University of Colorado, Denver
    National Institute on Aging (NIA)
    Active, not recruiting
    Advancing Understanding of Transportation Options (AUTO)
    Stroke | Multiple Sclerosis | Glaucoma | Brain Injuries | Macular Degeneration | Arthritis | Chronic Obstructive Pulmonary Disease | Parkinson Disease | Restless Legs Syndrome | Diabetic Retinopathy | Insomnia | Retinitis Pigmentosa | Obstructive Sleep Apnea | Dementia | End Stage Renal Disease | Sleep Apnea | Syncope | Seizures and other conditions
    United States
  • LMU Klinikum
    University of Pisa; German Federal Ministry of Education and Research; European...
    Recruiting
    Global Registry and Natural History Study for Mitochondrial Disorders
    Mitochondrial Diseases | MDS | Mitochondrial Myopathies | MELAS Syndrome | MIDD | Kearns-Sayre Syndrome | MERRF Syndrome | Barth Syndrome | Leigh Syndrome | MNGIE | LHON | Pearson Syndrome | NARP Syndrome | Coenzyme Q10 Deficiency | SANDO | SCAE | MIRAS | CPEO
    Austria, Germany, Italy
  • Burke Medical Research Institute
    Active, not recruiting
    Home Based Tele-exercise for People With Chronic Neurological Impairments (Telex)
    Stroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Spinal Cord Injuries | Neurologic Disorder | Hemiplegia | Hemiparesis | Friedreich Ataxia | Trauma, Brain | Transverse Myelitis
    United States
  • National Taiwan University Hospital
    Unknown
    Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals
    Hypertension | Diabetes | Dementia | Alzheimer Disease | Fabry Disease | Dry Eye Syndrome | Metabolic Disease | Healthy Individuals | Ocular Rosacea | Limbal Insufficiency | Phlyctenulosis | Graft Versus Host Disease in Eye
    Taiwan
  • University Hospital, Bordeaux
    Recruiting
    Functional Tests to Resolve Unsolved Rare Diseases. Rares. (RID)
    Intellectual Disability | Cystic Fibrosis | Neurodegeneration With Brain Iron Accumulation (NBIA) | Congenital Heart Defect | Albinism | Rubinstein-Taybi Syndrome | Periventricular Nodular Heterotopia
    France
  • Fred Hutchinson Cancer Center
    Active, not recruiting
    Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases
    Myasthenia Gravis | Neuromyelitis Optica | Autoimmune Disease | Chronic Inflammatory Demyelinating Polyneuropathy | Lambert Eaton Myasthenic Syndrome | Cerebellar Degeneration | Stiff Person Syndrome | Opsoclonus Myoclonus Syndrome | Neurologic Autoimmune Disease | Autologous Transplant Autoimmune | Multiple... and other conditions
    United States
  • University of Calgary
    Alberta Health services; University of Alberta
    Completed
    Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial (TNT)
    Stroke | Epilepsy | Autoimmune Diseases | Endocrine System Diseases | Diabetes | Hematologic Diseases | Genetic Diseases, Inborn | Traumatic Brain Injury | Autism Spectrum Disorder | Respiratory Disease | Cardiac Disease | Metabolic Disease | Renal Disease | Neuro-Degenerative Disease | Fetal Alcohol Spectrum Disorders | Gastro-Intestinal Disorder
    Canada
  • National Taiwan University Hospital
    Recruiting
    Taiwan Associated Genetic and Nongenetic Small Vessel Disease (TAG-SVD)
    Stroke | Magnetic Resonance Imaging | Fabry Disease | Cerebral Small Vessel Diseases | Cadasil | HTRA1-Related Autosomal Dominant Cerebral Angiopathy | COL4A1-Related Brain Small Vessel Disease With Haemorrhage | Next-generation Sequencing
    Taiwan
  • National Heart, Lung, and Blood Institute (NHLBI)
    National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
    Completed
    National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)
    Marfan Syndrome | Turner Syndrome | Ehlers-Danlos Syndrome | Loeys-Dietz Syndrome | Shprintzen-Goldberg Syndrome | FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation | Bicuspid Aortic Valve Without Known Family History | Bicuspid Aortic Valve With Family History | Bicuspid Aortic Valve With Coarctation and other conditions
    United States
  • Dana-Farber Cancer Institute
    Recruiting
    InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
    Lung Cancer | Cirrhosis | Barrett Esophagus | Hematologic Malignancy | Non-Alcoholic Fatty Liver Disease | Cancer Risk | Vulvar Intraepithelial Neoplasia | Childhood Cancer Survivors | Lung; Node | Non Alcoholic Steatohepatitis | Osteochondroma | Cancer Predisposition Syndrome | Hereditary Cancer Prediction | Adult... and other conditions
    United States
  • Sanford Health
    National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators
    Recruiting
    Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)
    Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions
    United States, Australia
  • RTI International
    Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators
    Enrolling by invitation
    Early Check: Expanded Screening in Newborns
    Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions
    United States
  • National Human Genome Research Institute (NHGRI)
    Recruiting
    A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
    Metabolic Disease | Purine-Pyrimidine Metabolism | AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2 | UNG, OMIM *191525, Hyper-IgM Syndrome 5 | NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency | UMPS, OMIM *613891, Orotic Aciduria | DHODH, OMIM *126064,... and other conditions
    United States
  • Centre Hospitalier Universitaire de Liege
    Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators
    Recruiting
    Baby Detect : Genomic Newborn Screening
    Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions
    Belgium

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