Clinical Trials on Major Salivary Gland Carcinoma

Total 4565 results

Roxane Laboratories

Completed

Bioequivalency Study of 5 mg Piolocarpine Tablets Under Fed Conditions

Dry Mouth

United States
MeiraGTx, LLC

Recruiting

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia (AQUAX2)

Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

United States, Canada
King Saud University

Completed

The Management of RT-induced Hyposalivation Using LLLT (REACH-LLLT)

Head and Neck Cancer

Saudi Arabia
Ain Shams University

Completed

Effectiveness of Thyme Honey in Management of Xerostomia in Post Radiation Cancer Patients

Head and Neck Cancer Patients

Egypt
University of Washington
National Cancer Institute (NCI)

Completed

L-lysine in Treating Oral Mucositis in Patients Undergoing Radiation Therapy With or Without Chemotherapy For Head and Neck Cancer

Mucositis | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Verrucous Carcinoma... and other conditions

United States
Massachusetts General Hospital
National Alliance for Research on Schizophrenia and Depression

Completed

Biochemical Brain Changes Correlated With The Antidepressant Effect Of Thyroid Hormones

Major Depressive Disorder

United States
National Institute of Dental and Craniofacial Research...

Completed

Structure and Functional Status of Parotid Glands Exposed to Therapeutic Irradiation

Radiation Injuries | Xerostomia

United States
Changhua Christian Hospital

Not yet recruiting

The Effect of Intervention About Dry Mouth and Thirst in Patients With Endotracheal Tube

Endotracheal Tube | Thirst | Dry Mouth

Taiwan
Pia Lopez Jornet

Completed

Effect of Photobiomodulation for Patients With Xerostomia (xeros)

Low-Level Light Therapy | Photobiomodulation

Spain
Nova Scotia Health Authority
Dalhousie University

Unknown

The Effect of Biotene® on the Symptoms of Xerostomia and Mastication and Swallowing

Xerostomia | Hyposalivation
Zhongshan People's Hospital, Guangdong, China

Recruiting

Xerostomia-optimised IMRT Versus Standard IMRT in NPC

Nasopharyngeal Carcinoma ,Xerostomia,Radiotherapy

China
MeiraGTx UK II Ltd

Completed

A Phase 1 Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity of AAV2hAQP1 in Subjects With Radiation-Induced Parotid Gland Hypofunction and Xerostomia

Head and Neck Cancer | Radiation-Induced Parotid Gland Hypofunction | Xerostomia Due to Radiotherapy

United States, Canada
Mansoura University

Unknown

Gender and Opioid Consumption (GenderOpioid)

Postoperative; Parotitis
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Symptoms of Frey's Syndrome

Parotid Neoplasms

Italy
Stanford University

Completed

Immunohistochemical & Immunoblot Analysis of NIS (Na+/I-Symporter) in Archival & Frozen Tissue Sample

Stomach Neoplasms | Breast Cancer | Thyroid Cancer | Salivary Gland Neoplasms

United States
Boston Children's Hospital

Completed

Effect of Childhood Radioiodine Therapy on Salivary Function

Hyperthyroidism | Xerostomia | Thyroid Cancer

United States
Proveca Pharma Limited

Recruiting

Double-blind, Placebo-controlled, Randomized Clinical Trial Comparing the Efficacy and Safety of Sialanar Plus orAl rehabiLitation Against Placebo Plus Oral Rehabilitation for chIldren and Adolescents With seVere Sialorrhoea and Neurodisabilties, (SALIVA)

Neurodevelopmental Disorders | Sialorrhea

France
University College, London

Completed

A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer (LEONIDAS-2)

Head and Neck Neoplasms | Xerostomia
Centre Hospitalier Universitaire de Besancon

Completed

Frequency of Xerostomia and Their Management in Upper Aerodigestive Tract Cancer Patients After the End of Radiotherapy (XEROSTOMIA)

Head and Neck Neoplasms

France
Hadassah Medical Organization

Unknown

Implications of Pacifier Use in Israeli Children

Drooling | Crossbite | Openbite

Israel
Emory University
National Institute of Mental Health (NIMH)

Completed

Thyroid Medication and Antidepressants for Treating Major Depression

Major Depression

United States
Ludwig-Maximilians - University of Munich

Completed

Quetiapine Prolong, Escitalopram and Hypothalamic-pituitary-adrenocortical (HPA) Axis Activity in Depressed Patients

Major Depression

Germany
Roxane Laboratories

Completed

Bioequivalency Study of 7.5 mg Pilocarpine Under Fed Conditions

Dry Mouth

United States
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Cevimeline 30 mg Capsules Under Fed Conditions

Dry Mouth

United States
NeuroHealing Pharmaceuticals Inc.
Michael J. Fox Foundation for Parkinson's Research

Completed

Study of the Safety and Efficacy of Tropicamide Thin Films to Reduce Hypersalivation in Parkinson's Patients

Sialorrhea (Excessive Drooling)

France
Chang Gung Memorial Hospital

Completed

TENS to Alleviate the Effect of Thirty After Surgery Xerostomia (Dry Mouth) After Surgery

Postoperative Complications

Taiwan
Università degli Studi di Sassari

Completed

Effect of a Self-adhering Material in Dental Hypersensitivity

Dentin Sensitivity | Xerostomia

Italy
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC

Terminated

Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection

HIV Infection | Unspecified Adult Solid Tumor, Protocol Specific | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Recurrent Breast Cancer | Recurrent Ovarian Epithelial Cancer | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult... and other conditions

United States
Sun Yat-sen University

Completed

Impact on Xerostomia for Nasopharyngeal Carcinoma Patients Treated With or Without Superficial Parotid Lobe-sparing Intensity-modulated Radiotherapy

Nasopharyngeal Carcinoma | Radiation-induced Xerostomia

China
National Cancer Institute (NCI)
Exelixis

Completed

Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer

Recurrent Thyroid Gland Carcinoma | Poorly Differentiated Thyroid Gland Carcinoma | Stage I Thyroid Gland Papillary Carcinoma | Stage II Thyroid Gland Papillary Carcinoma | Stage III Thyroid Gland Papillary Carcinoma | Tall Cell Variant Thyroid Gland Papillary Carcinoma | Stage I Thyroid Gland... and other conditions

United States
Hadassah Medical Organization

Completed

Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.

Major Depressive Disorder

Israel
National Cancer Institute (NCI)

Recruiting

Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors and Carcinomas

Neuroendocrine Tumors | Carcinoma, Neuroendocrine | Neuroendocrine Carcinomas | Carcinoma, Adrenal Cortical | Carcinoma, Adrenocortical

United States
Klus Pharma Inc.

Completed

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Cervical Cancer | Head and Neck Cancer | Mucoepidermoid Carcinoma | Pancreatic Cancer | Recurrent Prostate Cancer | Lung Cancer | Rectal Cancer | Solid Tumor | Prostate Cancer | Cholangiocarcinoma | Bile Duct Cancer | Recurrent Ovarian Carcinoma | Bladder Cancer | Skin Cancer | HER2-positive Breast Cancer | Rare Diseases | Colo-rectal Cancer and other conditions

United States
Tufts University

Recruiting

Effect of Whitening Agent With Emulsion Gel in Saliva and Halitosis

Xerostomia | Halitosis

United States
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Xerostomia in Patients With a Life-limiting Condition or Frailty

Xerostomia | Dry Mouth
Umraniye Education and Research Hospital

Unknown

Malignancy Predictors, Bethesda and TI-RADS Scores Correlated With Final Histopathology in Thyroid Diseases

Thyroid Diseases | Thyroid Neoplasms | Thyroid Cancer, Papillary | Thyroid Carcinoma | Thyroid Nodule | Aspiration | Thyroid Goiter | Thyroid Papillary Carcinoma | Multinodular Goiter, Adolescent | Solitary Thyroid Nodule | Multifocal Dysplasia

Turkey
Brock University
Dr. Peter C. Fritz, Periodontal Wellness & Implant Surgery

Completed

Periodontal Outcomes After Sanative Therapy

Periodontal Diseases | Xerostomia | Periodontal Pocket | Dry Mouth

Canada
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer

Tongue Cancer | Recurrent Colon Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral... and other conditions

United States
Samsung Medical Center

Completed

Intra-parotid Facial Nerve Imaging in Parotidectomy

Facial Nerve Paresis | Parotid Tumors

Korea, Republic of
You First Services

Completed

"Hyaluronan" Formulation for Type 2 Diabetic Patients With Dry Mouth

Xerostomia | Dry Mouth | Type 2 Diabetics

United States
National Institute of Dental and Craniofacial Research...

Recruiting

The Pathogenesis and Natural History of Sjogren's Disease

Sjogren's Syndrome | Pathogenesis | Salivary Gland

United States
National Institute of Dental and Craniofacial Research...

Terminated

Evaluation of Salivary Gland Dysfunction

Sjogren's Syndrome | Salivary Gland

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Acupuncture for Prevention of Radiation-Induced Xerostomia

Nasopharyngeal Cancer | Xerostomia | Mouth Dryness

China
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Completed

Lenvatinib and Pembrolizumab in Differentiated Thyroid Cancers (DTC)

Poorly Differentiated Thyroid Gland Carcinoma | Recurrent Differentiated Thyroid Gland Carcinoma | Columnar Cell Variant Thyroid Gland Papillary Carcinoma | Follicular Variant Thyroid Gland Papillary Carcinoma | Metastatic Thyroid Gland Follicular Carcinoma | Metastatic Thyroid Gland Papillary... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Sunitinib Malate in Treating Patients With Thyroid Cancer That Did Not Respond to Iodine I 131 and Cannot Be Removed by Surgery

Recurrent Thyroid Gland Carcinoma | Refractory Thyroid Gland Carcinoma | Stage III Thyroid Gland Follicular Carcinoma AJCC v7 | Stage IV Thyroid Gland Follicular Carcinoma AJCC v7 | Stage IV Thyroid Gland Papillary Carcinoma AJCC v7 | Stage IVA Thyroid Gland Follicular Carcinoma AJCC v7 | Stage... and other conditions

United States
Loma Linda University

Withdrawn

Saliva, Hyperbaric Oxygen Therapy, & Gland Function: A Prospective Study (SHOTGUN)

Xerostomia | Osteoradionecrosis of the Jaw

United States
Mayo Clinic

Recruiting

HEADLIGHT: Hypofractionated Proton Therapy for Head and Neck Cancers

Head and Neck Carcinoma | Metastatic Malignant Neoplasm in the Lymph Nodes | Nasal Cavity Carcinoma | Oral Cavity Carcinoma | Paranasal Sinus Carcinoma | Salivary Gland Carcinoma | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Hypopharyngeal Carcinoma | Laryngeal Carcinoma | Oropharyngeal Carcinoma and other conditions

United States
Tirat Carmel Mental Health Center
University of Michigan; The Nazareth Hospital, Israel; Ariel University

Completed

Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression

Major Depression

Israel
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Lenvatinib and Pembrolizumab for the Treatment of Stage IVB Locally Advanced and Unresectable or Stage IVC Metastatic Anaplastic Thyroid Cancer

Poorly Differentiated Thyroid Gland Carcinoma | Thyroid Gland Squamous Cell Carcinoma | Unresectable Thyroid Gland Carcinoma | Metastatic Thyroid Gland Carcinoma | Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8 | Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8

United States
National Institute of Dental and Craniofacial Research...

Recruiting

Characterization of Diseases With Salivary Gland Involvement

Healthy Volunteer | Sjogren's Syndrome | Salivary Gland Disease

United States

Clinical Trials on Major Salivary Gland Carcinoma

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