Clinical Trials on Major Adverse Cardiovascular Events

Total 864 results

University of Pittsburgh
American Heart Association; VA Pittsburgh Healthcare System

Completed

Decreasing Risk of Coronary Artery Disease in Schizophrenia by Omega-3 Fatty Acid Supplementation (CAD)

Coronary Artery Disease | Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Major Depression

United States
Fundación Centro Nacional de Investigaciones Cardiovasculares...
European Commission

Recruiting

REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs (RESILIENCE)

Lymphoma | Anthracycline-induced Cardiac Toxicity

Netherlands, Spain, Denmark, Germany, France, Portugal
LifeBridge Health

Recruiting

Quantification of Binding and Neutralizing Antibody Levels in COVID-19 Vaccinated Health Care Workers Over 1 Year

Inflammation | Vaccine Adverse Reaction | Thrombosis | Corona Virus Infection | COVID-19 Vaccine | Vaccine Response

United States
Stony Brook University
Gilead Sciences

Unknown

Novel Biomarkers and Echocardiography for Subclinical Cardiac Toxicity in Breast Cancer Patients Receiving Anthracyclines

Heart Failure | Breast Cancer | Biomarkers | Cardiotoxicity | Echocardiography | Anthracycline Induced Cardiomyopathy

United States
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma

Sarcoma | Cardiac Toxicity

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Canada, Switzerland
Cambridge University Hospitals NHS Foundation Trust

Unknown

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Nonmetastatic Breast Cancer

Breast Cancer | Perioperative/Postoperative Complications | Cardiac Toxicity

United Kingdom
Assistance Publique - Hôpitaux de Paris

Recruiting

Early Detection of Patients at Risk of Developing Anthracycline Cardiotoxicity With TEP/CT -FDG (DETECT)

Lymphoma, Non-Hodgkin | Lymphoma, Hodgkin

France
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); University of Toronto

Active, not recruiting

Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI (EMBRACE-MRI)

Breast Neoplasms

Canada
Fudan University

Completed

Comparison Study of Doxorubicin Versus Epirubicin-induced Cardiotoxicity in Patients With DLBCL

Lymphoma

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Stanford University

Not yet recruiting

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness

Obesity | Metabolic Syndrome | Bipolar Disorder | Bipolar and Related Disorders | Bipolar Depression | Weight Gain | Bipolar I Disorder | Ketogenic Dieting | Bipolar Disorder I | Bipolar II Disorder | Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Brain Metabolic Disorder | Bipolar Disorder, Type... and other conditions

United States
University Health Network, Toronto

Recruiting

Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation (TICATS)

Thalassemia Major

Canada
Ospedale Microcitemico
Azienda Sanitaria Locale di Cagliari

Completed

Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia Major (DFODFPTM)

Iron Overload | Cardiomyopathy

Italy
Norwegian School of Sport Sciences
Uppsala University

Recruiting

Effects of Exercise Training in Survivors of Lymphoma (LYMfit)

Cardiovascular Diseases | Lymphoma | Cardiotoxicity | Chemotherapeutic Toxicity | Physical Exercise

Norway, Sweden
University Hospital, Akershus
Norwegian Cancer Society; Helse Sor-Ost; ChromaDex, Inc.; Norwegian Breast Cancer...

Recruiting

Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients (NARNIA)

Heart Failure | Breast Cancer | Metastatic Breast Cancer | Cardiotoxicity | Cancer Therapy-Related Cardiac Dysfunction

Norway
Ass. Prof. Jan Nyman

Recruiting

Study on Proton Radiotherapy of Thymic Malignancies (PROTHYM)

Thymus Neoplasms | Cardiotoxicity | Pulmonary Toxicity

Sweden
Prof Corinne Faivre-Finn
The Leeds Teaching Hospitals NHS Trust; University of Leeds; Manchester University... and other collaborators

Recruiting

Avoiding Cardiac Toxicity in Lung Cancer Patients Treated With Curative-intent Radiotherapy (ACCOLADE)

Lung Cancer

United Kingdom
Pontificia Universidad Catolica de Chile

Completed

Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients

Cancer | Breast Cancer | Esophageal Cancer | Lung Cancer | Cardiotoxicity | Radiotherapy; Complications

Chile
Abramson Cancer Center of the University of Pennsylvania

Completed

Cardiotoxicity of Radiation Therapy (CTRT)

Breast Cancer | Lung Cancer | Mediastinal Lymphomas

United States
Groupe Hospitalier Pitie-Salpetriere

Completed

cARdiotoxicity Profile of aBIraTeRone in prostAte Cancer : a pharmacoviGilancE Study (ARBITRAGE)

Arrhythmias, Cardiac | Tachycardia, Supraventricular | Cardiac Failure | Atrial Fibrillation and Flutter

France
Fondazione del Piemonte per l'Oncologia

Unknown

Cardiotoxicity and Risk Factors in Patients With Colorectal Cancer Receiving Fluoropyrimidine

Colorectal Cancer

Italy
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer Group

Completed

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Australia, Canada
Osaka City University

Completed

Prevention of CHOP-induced Chronic Cardiotoxicity

Non-Hodgkin's Lymphoma

Japan
Seoul National University Hospital
Samjin Pharmaceutical Co., Ltd.

Recruiting

Comparison of Clopidogrel-based Antiplatelet Therapy Versus Warfarin as Secondary Prevention Strategy for AntiPhospholipid Syndrome-related STROKE (APS-STROKE)

Cardiovascular Diseases | Ischemic Stroke | Transient Ischemic Attack | Antiphospholipid Syndrome | Cerebrovascular Disease | Major Bleed

Korea, Republic of
Turku University Hospital
Academy of Finland

Not yet recruiting

Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage (Xe-SAH)

Cerebral Infarction | Subarachnoid Hemorrhage, Aneurysmal | Cardiac Event | Cerebral Ischemia | Cardiac Failure | Cerebral Injury

Finland, Sweden
Samsung Medical Center
Boston Scientific Corporation

Active, not recruiting

DEvice-Detected CArdiac Tachyarrhythmic Events and Sleep-disordered Breathing (DEDiCATES) (DEDiCATES)

Sleep Disorder | Cardiac Event | Cardiac Arrythmias | Cardiac Implantable Electronic Device

Korea, Republic of
Isfahan University of Medical Sciences

Unknown

Familial Hypercholesterolemia Amongst Patients With Acute Coronary Syndrome

Acute Coronary Syndrome | Familial Hypercholesterolemia | Cardiac Event

Iran, Islamic Republic of
Azienda Ospedaliera Città della Salute e della...

Completed

Subclinical Cardio-toxicities Evaluation With Strain Rate Echocardiography After Chemotherapy and/or Mediastinal Radiotherapy in Patient With Lymphoma (Cardiocare)

Lymphoma, Non-Hodgkin | Hodgkin Lymphoma | Toxicity, Cardiac

Italy
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); MSH-UHN AMO Innovation Fund

Terminated

Efficacy of Cardio-Oncology Rehabilitation Exercise for Women With Breast Cancer and Treatment Related Cardiotoxicity (CORE)

Breast Cancer | Heart Failure, Systolic | Left Ventricular Dysfunction

Canada
Neuroganics LLC
Ramos Injury Law Firm

Recruiting

National Vaccine Adverse Event Reporting Survey and Etiology (NVAERS)

COVID-19 | Vaccine Adverse Reaction | Vaccine Reaction | Vasculitis | Neuritis | Thrombocytopenia | Influenza | Corona Virus Infection | Blood Clot | Guillain-Barré | Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use | GWAS | Genetic Sequencing

United States
King's College Hospital NHS Trust
Advanced Accelerator Applications

Not yet recruiting

Carcinoid Heart Disease and Peptide Receptor Radiotargetted Therapy (CHARRT)

Carcinoid Tumor | Carcinoid Syndrome | Carcinoid Heart Disease
Vejle Hospital
Region of Southern Denmark

Recruiting

Prevention of Chest Pain in Chemo-treated Cancer Patients (CATCH)

Chest Pain | Acute Coronary Syndrome | Cardiotoxicity | Chemotherapeutic Toxicity | Coronary Artery Calcification | Solid Carcinoma | 5-Fluorouracil Toxicity

Denmark
Washington University School of Medicine
Myocardial Solutions

Active, not recruiting

PROactive Evaluation of Function to Avoid CardioToxicity (PROACT)

Sarcoma | Lymphoma | Leukemia | Breast Cancer | Lung Cancer | Cardiotoxicity | Myeloma

United States
Abbott Medical Devices

Completed

SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)

Myocardial Ischemia | Coronary Artery Disease | Stent Thrombosis | Vascular Disease | Coronary Artery Stenosis | Stents | Total Coronary Occlusion | Coronary Artery Restenosis

United States
The Cleveland Clinic

Recruiting

Global Cardio Oncology Registry (G-COR)

Cardiovascular Diseases | Breast Cancer | Cardiotoxicity | Hematologic Malignancy | Immune Checkpoint Inhibitor-Related Myocarditis

United States
Abramson Cancer Center at Penn Medicine
American Heart Association

Recruiting

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer (PCT)

Cardiovascular Diseases | Prostate Cancer | Drug-Related Side Effects and Adverse Reactions | Cardiotoxicity

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Avon Foundation

Terminated

Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin

Breast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | Stage III Breast Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum

Breast Cancer | Malignant Neoplasm | Cardiac Toxicity

United States
Ospedale Andrea Tortora di Pagani

Unknown

Evaluation of Cardiotoxicity and Hypertension in Patients With Non Metastatic Castration Resistant Prostatic Carcinoma (Apa-CARDIO1)

Castration-resistant Prostate Cancer

Italy
Unity Health Toronto
Hoffmann-La Roche

Unknown

Assessment of Cardiotoxicity by Cardiac Magnetic Resonance (CMR) in Breast Cancer Patients Receiving Trastuzumab

Stage I-IV Breast Cancer (Neo-adjuvant, Adjuvant, Locally Advanced and Metastatic)

Canada
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Recurrence and Bleeding in Colorectal Cancer Patients With Cancer-associated Venous Thrombembolism

Bleeding | Colo-rectal Cancer | Major Bleed | Thrombosis, Venous

China
Joseph Calabrese, MD
Takeda Pharmaceuticals North America, Inc.

Completed

Pioglitazone for the Treatment of Major Depressive Disorder Comorbid With Metabolic Syndrome

Depressive Disorder, Major | Metabolic Syndrome X

United States
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Recruiting

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

Gastrointestinal Diseases | Heart Failure | Infections | Urologic Diseases | Shock | Hematologic Diseases | Critical Illness | Rheumatic Diseases | Asthma | Renal Failure | Neurologic Disorder | COPD Exacerbation | Cardiac Event | Oncology Problem | Arrythmia | Renal Disease

United States
Children's Cancer Hospital Egypt 57357

Completed

Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia

Cardiotoxicity | Bone Tumor | Acute Myeloid Leukemia in Children

Egypt
European Organisation for Research and Treatment...
Ipsen

Withdrawn

Lanreotide Combined With Telotristat Ethyl or Placebo for the First-line Treatment in Patients With Advanced Well Differentiated Small Intestinal Neuroendocrine Tumours (siNET) With Highly-functioning Carcinoid Syndrome (TELEFIRST)

Small Intestinal NET | Carcinoid Heart Disease
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy (CLARITY)

Cardiotoxicity | Radiation Toxicity | Lung Cancer Stage III | Lung Cancer Stage II

United States
Ente Ospedaliero Ospedali Galliera

Completed

Prevalence of Pulmonary Hypertension (PAH) in Patients With Thalassemia (PAH2010)

Pulmonary Arterial Hypertension | Thalassemia Major | Thalassemia Intermedia

Italy
University Hospital, Basel, Switzerland

Completed

Long-term Mortality in Diabetics Undergoing Major Surgery

Diabetes Mellitus | Coronary Heart Disease | Major Non-cardiac Surgery

Switzerland
Rajaie Cardiovascular Medical and Research Center
National Institute for Medical research and Development (NIMAD); Abidi Pharmaceuticals

Terminated

RIvoraxaban in Mitral Stenosis (RISE MS)

Atrial Fibrillation | Rheumatic Heart Disease | Mitral Stenosis | Anticoagulant Adverse Reaction

Iran, Islamic Republic of

Clinical Trials on Major Adverse Cardiovascular Events

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Medical Conditions

Drug Interventions

CROs by country

CROs in Mongolia

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Rare Diseases

Drug Interventions

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