Clinical Trials on Marfan Syndrome Cardiovascular Manifestations

Total 9781 results

Eunice Kennedy Shriver National Institute of Child...

Completed

The Role of Susceptibility to Thrombosis in the Pseudotumor Cerebri of Nephropathic Cystinosis: A Case-Control Study

Pseudotumor Cerebri | Cystinosis

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Immune Response of Patients With Chronic, Staphylococcus Aureus-infected Wounds (ORISA)

Diabetic Foot | Foot Ulcer | Leg Ulcer | Bacteremia | Infection

France
Genetic Disease Investigators
Optos, PLC

Completed

Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Multiple Sclerosis | Ehlers-Danlos Syndrome

United States
Prof. Dr. Sonia Lippke
Dr. Becker Hospital Group; Dr. Becker Kiliani Clinic; Dr. Becker Clinic Möhnesee and other collaborators

Completed

ASAP - Assisted Immediate Augmented Post-/Long-COVID Plan for Patients Infected With COVID-19 (ASAP)

Psychological Distress | Healthy Lifestyle | Psychological Adjustment | Psychological Disorder | Psychological Disease | Long-COVID | Psychosomatic Disorder | Post-COVID | Psychological Impairment | Physiological Disease | Physiological Disorder | Physiological Impairment | Physiological Adjustment

Germany
Wake Forest University Health Sciences

Completed

HIRREM Developmental Study

Sleep Initiation and Maintenance Disorders | Hot Flashes | Anxiety | Headache | Traumatic Brain Injury | Post-Traumatic Stress Disorder | Post Concussion Symptoms

United States
Sanguine Biosciences

Completed

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Depression | Melanoma | Epilepsy | Lymphoma | Multiple Sclerosis | Kidney Cancer | Cervical Cancer | Diabetes Mellitus | Leukemia | Breast Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Parkinson's Disease | Systemic Lupus Erythematosus | Multiple Myeloma | Hepatitis B | Insomnia | Colorectal Cancer | HIV/AID... and other conditions

United States
Washington University School of Medicine

Active, not recruiting

Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes (CHARMED)

Heart Diseases | Virus Diseases | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Diabetes Mellitus, Type 1 | Enterovirus Infections | Pregnancy Complications | Heart Defects, Congenital | Viremia | Congenital Heart Disease | Pregnancy in Diabetic | Enterovirus | Prenatal Infection | Prenatal

United States
Pinar Yasar

Completed

The Relationship Between Urinary Incontinence and Motor Symptoms

Stroke | Urinary Incontinence | Motor Skills Disorders

Turkey
CENTOGENE GmbH Rostock

Completed

Screening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP) (TRAP2-1)

Neuropathic Pain | Orthostatic Hypotension | Cardiac Failure | Gastrointestinal Disorders | Polyneuropathy, Amyloid

Spain, Austria, Hungary, North Macedonia, Poland, Serbia
University of Pittsburgh

Completed

COVID-19 Brain Injury

Ischemic Stroke | Traumatic Brain Injury | Subarachnoid Hemorrhage | Hemorrhagic Stroke | Intracerebral Hemorrhage | Status Epilepticus | Sars-CoV2 | Severe Neurologic Injury

United States
Junior Doctors Network-Hellas
Andreas Papandreou Rhodes General Hospital; Hellenic Red Cross Hospital

Completed

Adrenaline Reduces Ecchymoses and Hematomas and Improves Quality of Life After Classic Saphenous Vein Stripping (ARESQOLSAVES)

Venous Stasis | Venous Insufficiency of Leg | Venous Reflux | Ecchymosis | Venous Disease | Bruising | Venous Insufficiency (Chronic)(Peripheral) | Subcutaneous Haematoma

Greece
Infectopharm Arzneimittel GmbH
INPADS GmbH; Dr. Oestreich + Partner GmbH

Recruiting

Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

Respiratory Tract Infections | Sepsis | Encephalitis | Bacterial Infections | Intraabdominal Infections | Bacteremia | Skin Diseases, Bacterial | Pneumonia, Bacterial | Urinary Tract Infections | Meningitis, Bacterial | Central Nervous System Bacterial Infections | Soft Tissue Infections | Endocarditis, Bacterial | Bone Diseases, Infectious and other conditions

Germany, Austria, Greece, Italy, United Kingdom
Massachusetts General Hospital

Completed

Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan

Fabry Disease | Mitochondrial Disease | Small Fiber Neuropathy | Ehlers Danlos Syndrome

United States
National University of Singapore
National Heart Centre Singapore

Completed

Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI

Coronary Artery Disease | Diabetes Mellitus | Obstructive Sleep Apnea

Singapore
Istanbul Medeniyet University

Completed

Methylenetetrahydrofolate Reductase Deficiency in Ischemic Stroke

Epilepsy | Ischemic Stroke | Hyperhomocysteinemia, Thrombotic, Cbs-Related

Turkey
National Institute of Arthritis and Musculoskeletal...
The Cleveland Clinic; Rare Diseases Clinical Research Network; Office of Rare...

Completed

Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis

Giant Cell Arteritis | Takayasu's Arteritis

United States, Canada
Emory University
National Cancer Institute (NCI)

Withdrawn

Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection)

Coronary Artery Disease | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Cerebrovascular Accident | Chronic Renal Failure | Malignant Neoplasm | SARS Coronavirus 2 Infection

United States
VA Office of Research and Development

Active, not recruiting

Addressing Sleep Apnea Post-Stroke/TIA (ASAP)

Ischemic Stroke | Obstructive Sleep Apnea | Transient Ischemic Attack (TIA)

United States
Bispebjerg Hospital

Withdrawn

Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction (REPARE)

Acute Kidney Injury | Hernia, Ventral | Restrictive Lung Disease | Intraabdominal Hypertension | Hernia Incisional

Denmark
Helse Nord-Trøndelag HF

Completed

Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic

Liver Failure | HEART DISEASE | DEPRESSIVE DISORDER | Alcoholic Neuropathy

Norway
Nanjing Medical University

Completed

CPAP Treatment and Postoperative Outcomes in Patients With Rheumatic Valvular Heart Disease (CPAP)

Obstructive Sleep Apnea | Rheumatic Valvular Heart Disease

China
Shenzhen Ausa Pharmed Co.,Ltd
Nanfang Hospital of Southern Medical University

Withdrawn

CSPPT- Chronic Kidney Diseases Study (CSPPT-CKD)

Hypertension | Hyperhomocysteinemia

China
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Preventing Sickle Cell Kidney Disease

Hypertension | Proteinuria | Sickle Cell Disease | Anemia, Sickle Cell | Kidney Disease

United States
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Nurses' Health Study (Cardiovascular Component)

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus | Angina Pectoris | Menopause | Cerebrovascular Accident | Pulmonary Embolism | Postmenopause
University of California, Los Angeles

Completed

Smarter Care Virginia, Examining Low-Value Care in Virginia

Eye Diseases | Chronic Kidney Diseases | Low Back Pain | Surgery | Cardiac Disease

United States
Kobe University
Mochida Pharmaceutical Company, Ltd.

Completed

Protective Effect of EPA on Cardiovascular Events

Myocardial Infarction, Unstable Angina Pectoris, Sudden Cardiac Death, Stroke, Peripheral Artery Disease

Japan
University College, London
Wellcome Trust; National Institute for Health Research, United Kingdom

Unknown

Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease

Myocardial Infarction | Heart Failure | Stroke | Peripheral Arterial Disease | Atrial Fibrillation | Bleeding | Coronary Heart Disease | Stable Angina | Death, Sudden, Cardiac

United Kingdom
Singapore Eye Research Institute
University of Melbourne; Curtin University; Singapore National Eye Centre; Ministry...

Unknown

Living Successfully With Chronic Eye Diseases (ADAPT-LAH)

Glaucoma | Diabetic Retinopathy | Age-related Macular Degeneration | Low Vision | Chronic Diseases

Singapore
Medipol University

Completed

Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia

Perinatal Asphyxia | Hypoxic-Ischemic Encephalopathy | Swallowing Disorder | Feeding; Difficult, Newborn | Speech Therapy | Feeding Disorder of Infancy or Early Childhood

Turkey
University of Rostock
German Center for Neurodegenerative Diseases (DZNE); Fraunhofer Institute

Completed

SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia (SAIN_UMR)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Frontotemporal

Germany
Groupe Éthique et Santé
Novo Nordisk A/S; University Grenoble Alps; Lyon Est University

Not yet recruiting

Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients (SCOOP-RNPC) (SCOOP-RNPC)

Cardiovascular Diseases | Sleep Apnea, Obstructive | NAFLD | Overweight and Obesity | Metabolic Disease | NASH | Diabete Type 2
Michael Arzt

Recruiting

Sleep-disordered Breathing and Perioperative Atrial Fibrillation in Cardiac Surgery (CONSIDER-AF)

Coronary Artery Disease | Atrial Fibrillation | Sleep-disordered Breathing (SDB) | Elective Coronary Artery Bypass Grafting (CABG) Surgery

Germany
University Hospital, Montpellier

Terminated

The Role of the Coagulation Pathways in Recurrent Angioedema (Angiocoag)

Chronic Spotaneous Urticaria, Idiopathic Non Histaminergic Angioderma, Hereditary Angioedema With C1 Inhibitor Deficiency

France
The University of Hong Kong

Terminated

Endothelial Damage and Atherosclerosis in Obstructive Sleep Apnea

Insulin Resistance | Obstructive Sleep Apnea | Oxidative Stress | Endothelial Function

Hong Kong
University of Saskatchewan

Completed

Sleep Disordered Breathing and Gestational Hypertension

Obstructive Sleep Apnea | Sleep Disordered Breathing | Preeclampsia | Gestational Hypertension

Canada
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Phase IA Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia

Myocardial Fibrosis | Cardiomyopathies | Friedreich Ataxia | Cardiac Hypertrophy

United States
Erasmus Medical Center

Recruiting

PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions (PRESENT)

Coronary Artery Disease | Stable Angina | Percutaneous Coronary Intervention | Unstable Angina | Multi Vessel Coronary Artery Disease | Non-ST Elevation Myocardial Infarction | Optical Coherence Tomography

Netherlands
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Acquired Pure Red Cell Aplasia | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Acquired Amegakaryocytic Thrombocytopenia
Stanford University
Patient-Centered Outcomes Research Institute

Completed

Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study (SMART DOCS)

Insomnia | Obstructive Sleep Apnea of Adult | Circadian Rhythm Sleep Disorder | Sleep Related Movement Disorders | Narcolepsy and Hypersomnia | Parasomnia

United States
Centre Hospitalier Universitaire, Amiens

Completed

Evaluation and Characterization of Behavioural Disorders and Dementias by the Behavioural Dysexecutive Syndrome Inventory (BDSI) (ISDC)

Alzheimer Disease | Frontotemporal Dementia | Dementia, Vascular | Semantic Dementia | Huntington Disease

France
University of Washington
National Cancer Institute (NCI)

Completed

Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
University of California, Davis
VA Northern California Health Care System; Center for Medicinal Cannabis Research

Completed

Effects of Vaporized Marijuana on Neuropathic Pain

Multiple Sclerosis | Reflex Sympathetic Dystrophy | Neuropathic Pain | Peripheral Neuropathy | Spinal Cord Injury | Post-herpetic Neuralgia

United States
Central Carolina Surgery, PA
EndoVx, Inc.

Terminated

Laparoscopic Adjustable Gastric Banding With Truncal Vagotomy

Hypertension | Diabetes | Urinary Incontinence | Obstructive Sleep Apnea | Hypercholesterolemia | Morbid Obesity | Hypertriglyceridemia
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
Thomas Jefferson University

Recruiting

Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Hodgkin Lymphoma | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma and other conditions

United States
Polyphor Ltd.

Completed

Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malignancies

Myeloproliferative Disorders | Adult Acute Lymphoblastic Leukemia in Remission | Chronic Lymphocytic Leukemia (CLL) | Myelodysplastic Syndrome (MDS) | Acute Myeloid Leukemia in Remission | Chronic Myelogenous Leukemia (CML) | Multiple Myeloma (MM) | Non-Hodgkin's Lymphoma (NHL) or Hodgkin's Disease...

United States
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases (TRANSREG)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Psoriasis | Systemic Sclerosis | Crohn's Disease | Ulcerative Colitis | Idiopathic Thrombocytopenic Purpura | Autoimmune Hepatitis | Wegener's Granulomatosis | Ankylosing Spondylitis | Behcet's Disease | Takayasu's Disease | Sclerosing Cholangitis | Gougerot-sj...

France
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) (BAH242)

Autoimmune Diseases | Systemic Lupus Erythematosus | Systemic Sclerosis | Lupus Nephritis | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Granulomatous Polyangiitis

China
Virginia Commonwealth University
Massey Cancer Center

Completed

Adoptive Immunotherapy in Relapsed Hematological Malignancy: Early GVHD Prophylaxis

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Hodgkin's Lymphoma | Recurrent Hodgkin Lymphoma | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Recurrent Non-Hodgkin Lymphoma | Recurrent Plasma... and other conditions

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Collecting and Storing Tissue and DNA Samples From Patients Undergoing a Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United States

Clinical Trials on Marfan Syndrome Cardiovascular Manifestations

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo, DR of

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations