Clinical Trials on Mechanical Ventilation Outcomes in South Africa

Total 38 results

University of KwaZulu
University of Cape Town; African Perioperative Research Group (APORG); Safe Surgery...

Completed

An African, Multi-centre Evaluation of Patient Care and Clinical Outcomes for Paediatric Patients Undergoing Surgery (ASOS-Paeds)

Surgery | Perioperative/Postoperative Complications | Perioperative Outcomes | Outcome Assessment | Prospective Studies | Paediatrics | Hospital Mortality | Paediatric Surgery | Developing Countries

South Africa, Sudan
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Medical Research Institute... and other collaborators

Enrolling by invitation

The TEAM Long-Term Cohort Study (A Sub-study of TEAM(III))

Critically Ill | Mechanical Ventilation | Long Term Outcome

Australia
Centre for the AIDS Programme of Research in South...

Completed

Trial to Assess the Impact of PrEP to Tenofovir Gel on the Efficacy of Tenofovir-containing ART on Viral Suppression (TOAST)

Antiretroviral Treatment Outcomes

South Africa
University of Witwatersrand, South Africa

Completed

The HIV Testing Trends and Outcomes at a Johannesburg Trauma ICU Unit

Outcome, Fatal

South Africa
Medical University of South Carolina

Terminated

Feasibility of Music Therapy for Spontaneous Breathing Trials

Intubation | Mechanical Ventilation | Music Therapy | Spontaneous Breathing Trial

United States
Duke University
Johns Hopkins University; National Institutes of Health (NIH); Vanderbilt University... and other collaborators

Terminated

DOSE Trial of Opioid Sparing Effect (DOSE)

Critically Ill | Dexmedetomidine | Mechanical Ventilation Complication

United States
National Institute of Environmental Health Sciences...

Completed

Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa

HIV Infections | Malaria | Pregnancy Outcome | Stillbirth | Spontaneous Abortion

South Africa
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia

Completed

Early Goal-Directed Sedation Compared With Standard Care in Mechanically Ventilated Critically Ill Patients (SPICE III RCT)

Critical Illness and Mechanical Ventilation

Australia, United Kingdom, Italy, New Zealand, Malaysia, Ireland, Switzerland, Saudi Arabia
Medical University of South Carolina

Completed

Safety and Efficacy of a Novel Facemask for Positive Pressure Ventilation

Anesthesia Induction Ventilation

United States
Medical University of South Carolina

Completed

Safety and Efficacy of the Tao Facemask for Positive Pressure Ventilation in the Patients With Significantly Elevated BMIs

Anesthesia Induction Ventilation

United States
Brno University Hospital
Simulation Centre of the Faculty of Medicine of Masaryk University

Completed

Simulation-based Comparative Study on Efficiency of Ventilation During Paediatric Cardiopulmonary Resuscitation (PEDIVENT)

Simulated Pediatric CRP Ventilation

Czechia
Foundation for Professional Development (Pty) Ltd
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes

HIV/AIDS | Pregnancy | Cost-effectiveness | Antenatal Care | Chlamydia Trachomatis | Vaginal Microbiome | Birth Outcomes | Sexually Transmitted Infection | Neisseria Gonorrhoeae | Trichomonas Vaginalis

South Africa
Royal North Shore Hospital

Completed

Wearable and Patient-reported Outcome-based Continuous Assessment and Support Alerts in Palliative Care (wePRO-CASA)

Cancer | Palliative Care | Patient Reported Outcome Measures | Caregiver | Digital Health | Wearable Electronic Devices

Australia
Walsh University
Proaxis Therapy

Withdrawn

Influence of Patient-Informed Choice in a Novel Treatment Model for LBP

Mechanical Low Back Pain

United States
University of Athens
Academy of Athens

Completed

Clinical and Biological Markers in Acute Respiratory Failure

Acute Respiratory Distress Syndrome | Ventilator-Associated Pneumonia

Greece
Australian and New Zealand Intensive Care Research...
The Alfred

Not yet recruiting

Trial of ECMO to De-Sedate, Extubate Early and Mobilise in Hypoxic Respiratory Failure (REDEEM)

Pneumonia | Extracorporeal Membrane Oxygenation | Mechanical Ventilation Complication | Hypoxemia | COVID-19 Respiratory Infection | Acute Respiratory Distress Syndrome Due to COVID-19

Australia, Germany
The George Institute
Sunnybrook Health Sciences Centre; Imperial College London

Completed

Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients (SuDDICU)

Sepsis | Critical Illness | Septic Shock | Ventilator Associated Pneumonia

Australia, Canada, United Kingdom
Brno University Hospital
Masaryk University

Withdrawn

Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic (MOVE) (MOVE)

Basic Life Support Ventilation

Czechia
Hospira, now a wholly owned subsidiary of Pfizer

Completed

A Safety and Efficacy Study of Dexmedetomidine in ICU Patients Requiring Continuous Sedation

Mechanically Ventilated and Intubated Subjects

United States, Australia, Argentina, Brazil, New Zealand
Australian and New Zealand Intensive Care Research...
Monash University; The Alfred; St Vincent's Hospital, Sydney; Royal Prince Alfred... and other collaborators

Completed

Extracorporeal Membrane Oxygenation Physical Training (ECMO-PT)

Extracorporeal Membrane Oxygenation Complication | Critically Ill, Mechanically Ventilated

Canada, Australia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Intensive Care National... and other collaborators

Completed

Treatment of Invasively Ventilated Adults With Early Activity and Mobilisation (TEAM(III))

Critically Ill, Mechanically Ventilated

Australia, New Zealand, United Kingdom, Ireland, Germany
Pfizer

Completed

A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia

Ventilator-associated Pneumonia (VAP) | Nosocomial Pneumonia (NP)

Bulgaria, France, Italy, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Turkey, United Kingdom, Vietnam, Philippines, China, Ukraine, Argentina, Brazil, Hungary, Romania, India, Japan, Taiwan, Latvia, Czechia, Slov... and more
Lungpacer Medical Inc.

Terminated

A Protocol Comparing Temporary Transvenous Diaphragm Pacing to Standard of Care for Weaning From Mechanical Ventilation (RESCUE3)

Ventilator Induced Diaphragm Dysfunction

United States, France, Germany
Arsanis, Inc.

Terminated

Prevention of S. Aureus Pneumonia Study in Mechanically Ventilated Subjects Who Are Heavily Colonized With S. Aureus.

Pneumonia, Ventilator-associated | Pneumonia, Staphylococcal

United States, Spain, France, Czechia, Portugal, Israel, Romania, Russian Federation, Hungary, Poland, Ukraine, India, Austria, Georgia, Serbia, South Africa
Aridis Pharmaceuticals, Inc.

Completed

Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301 (AR-301-002)

Staphylococcus Aureus | Pneumonia, Ventilator-Associated | Infection, Bacterial | Lung Infection

Belarus, Belgium, Brazil, China, Estonia, France, Georgia, Israel, Latvia, Mexico, Russian Federation, South Africa, Spain, Turkey, Ukraine
Medical University of South Carolina
Massachusetts General Hospital; University of Miami; Yale University; University... and other collaborators

Active, not recruiting

Registry of Emergent Large veSsel oCclUsion duE to IntraCranial AtherosclerosiS (RESCUE-ICAS)

Large Vessel Occlusion | Mechanical Thrombectomy | Intracranial Stenosis

United States, Switzerland, Germany, Italy, Portugal, Saudi Arabia
University of Sydney
University of Pennsylvania; University of California, San Diego; University of... and other collaborators

Completed

Appropriate Oxygen Levels for Extremely Preterm Infants: a Prospective Meta-analysis (NeOProM)

Infant, Newborn, Diseases | Infant, Premature, Diseases | Retinopathy of Prematurity | Bronchopulmonary Dysplasia | Infant, Very Low Birth Weight

Australia
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

CTTI Risk Factors for HABP/VABP Study (PROPHETIC)

Pneumonia, Bacterial | Pneumonia, Ventilator-Associated | Pneumonia, Hospital-Acquired

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants

Lung Diseases | Bronchopulmonary Dysplasia

United States
Mallinckrodt

Completed

Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants

Bronchopulmonary Dysplasia

United States, Canada
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia (BPD)

Bronchopulmonary Dysplasia

United States
Oak Hill Bio Ltd

Terminated

Safety and Efficacy Outcomes Following Previously Administered Short-Term Treatment With SHP607 in Extremely Premature Infants

Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Chronic Lung Disease of Prematurity | Retinopathy of Prematurity (ROP)

United States, Italy, United Kingdom
Roberta Ballard
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia (TOLSURF)

Bronchopulmonary Dysplasia

United States
Shionogi

Completed

Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens (CREDIBLE - CR)

Sepsis | Bloodstream Infections (BSI) | Hospital Acquired Pneumonia (HAP) | Complicated Urinary Tract Infection (cUTI) | Healthcare-associated Pneumonia (HCAP) | Ventilator Associated Pneumonia (VAP)

United States, Brazil, Croatia, France, Germany, Greece, Guatemala, Israel, Italy, Japan, Korea, Republic of, Spain, Taiwan, Thailand, Turkey, United Kingdom
Shionogi

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Participants

Gram-negative Bacterial Infections | Complicated Urinary Tract Infection (cUTI) | Hospital Acquired Bacterial Pneumonia (HABP) | Ventilator Associated Bacterial Pneumonia (VABP)

United States, Australia, Greece, Lithuania, Mexico, Philippines, Spain, Ukraine, Panama
OHB Neonatology Ltd.

Recruiting

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Chronic Lung Disease of Prematurity | Retinopathy of Prematurity (ROP)

Finland, United States, France, Italy, United Kingdom, Germany, Canada, Ireland, Japan, Netherlands, Portugal, Spain, Sweden
Medtronic

Recruiting

Product Surveillance Registry (PSR)

Coronary Artery Disease | Renal Insufficiency | Neurological Disorders | Intracranial Aneurysm | Surgical Procedures, Operative | Respiratory Therapy | Minimally Invasive Surgical Procedures | Cardiac Rhythm Disorders | Urological Disorders | Cardiovascular Disorders | Digestive Disorders | Mechanical Circulatory... and other conditions

China, France, Italy, United States, Spain, Australia, Belgium, Denmark, Germany, Greece, Hungary, Israel, Japan, Korea, Republic of, Malaysia, Netherlands, Norway, Portugal, Serbia, Sweden, Switzerland, United Kingdom, Argentina, Brazil and more
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada

Clinical Trials on Mechanical Ventilation Outcomes in South Africa

Sponsors and Collaborators

Medical Conditions

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CROs by country

CROs in Guatemala

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