Clinical Trials on Meningitis, Bacterial

Total 17958 results

University of North Carolina, Chapel Hill

Completed

Auditory Brainstem Implantation in Young Children

Developmental Cochlear Nerve Deficiency | Acquired Cochlear Nerve Deficiency | Cochlear Aplasia | Post-meningitis Cochlear Ossification | Cochlear Malformation

United States
Jiangsu Province Centers for Disease Control and...
Royal (Wuxi) Biological Co., LTD

Completed

Phase 3 Study of A Group A, C Polysaccharide Meningococcal and Type b Haemophilus Influenzal Conjugate Vaccine

Influenza | Meningitis

China
Jacob Bodilsen

Not yet recruiting

Aciclovir Versus Placebo for HSV-2 Meningitis (AMEN)

Herpes Simplex 2 | Meningitis, Viral
M.D. Anderson Cancer Center
Reata Pharmaceuticals, Inc.

Terminated

RTA 744 Injection in Patients With Leptomeningeal Disease

Lymphoma | Leukemia | Solid Tumor | Brain Tumor | Neoplastic Meningitis

United States
Gamaleya Research Institute of Epidemiology and...

Not yet recruiting

Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV

Gram-Negative Bacterial Infections | Bacteremia Caused by Gram-Negative Bacteria | Gram Negative Pneumonia
The Methodist Hospital Research Institute
M.D. Anderson Cancer Center; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

Antibiotic Resistant Infection | Clostridium Difficile | Antimicrobial Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin Resistant Enterococci Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection | Extended Spectrum Beta-Lactamase...

United States
National Institute of Allergy and Infectious Diseases...
International Maternal Pediatric Adolescent AIDS Clinical Trials Group

Completed

Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth

HIV Infections | Meningitis

United States, Puerto Rico
Nantes University Hospital

Completed

Diagnostic Performance of Clinical Signs Patients Suspected of Meningitis to Emergencies (MEDWATCH)

Meningitis

France
Georgetown University

Terminated

Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain

Meningitis

United States
Nantes University Hospital

Completed

Pharmacological Study of High Doses of Ceftriaxone in Meningitidis

Meningitis | Neurological Infections

France
Assistance Publique - Hôpitaux de Paris

Completed

Interest of the Detection of Hyper-virulent Clone ST17 of Group B Strep (GBS) for the Prevention of Neonatal GBS Meningitis (Col-Strepto B)

Neonatal Infections Colonize With Group B Streptococci

France
Pfizer

Completed

Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis

HIV Infections | Meningitis

United States
Institute of Tropical Medicine, Belgium
Universiteit Antwerpen; Victor Babes Hospital, Bucharest, Romania

Withdrawn

Prospective Investigation of Oxidative Stress in West Nile Virus Infection (PROWENI)

Oxidative Stress | West Nile Virus | West Nile Fever | West Nile Fever Encephalitis | West Nile Fever Meningitis | West Nile Meningitis | West Nile Virus Meningoencephalitis | West Nile Fever Meningoencephalitis | West Nile Fever With Neurologic Manifestation

Romania
Xuanwu Hospital, Beijing

Recruiting

Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia

Syringomyelia

China
International Extranodal Lymphoma Study Group (IELSG)

Withdrawn

A Phase I Study of Intrathecal Rituximab in Patients With Lymphomatous Meningitis

Lymphoma, B Cell
University of Liverpool
Oswaldo Cruz Foundation; University of Warwick; National Institute for Health... and other collaborators

Active, not recruiting

BIGlobal Intervention Study: Improving Diagnosis and Management of Suspected Brain Infections Globally

Encephalitis | Meningitis | Abscess Brain

India, Brazil, Malawi
University of Oxford
Novartis Vaccines

Completed

Understanding the Immune Response to Meningitis Vaccines

Meningitis | Septicemia

United Kingdom
David M. Jackman, MD
Massachusetts General Hospital; AstraZeneca

Completed

High Dose Gefitinib for the Treatment of Carcinomatous Meningitis in Adult Patients With Non-Small Cell Lung Cancer and Known or Suspected EGFR Mutations

Non-Small Cell Lung Cancer

United States
University of Alabama at Birmingham

Terminated

Early Versus Expectant Treatment of Ureaplasma Infection in Very Low Birth Weight Neonates

Respiratory Tract Infections | Bacteria Infection

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Centers for Disease Control and Prevention; Wageningen University and Research

Completed

The Role of the Intestinal Microbiome in Enteric and Systemic Vaccine Immune Responses (Rota-biome)

Tetanus | Rotavirus Infections | Reaction - Vaccine Nos | Intestinal Bacteria Flora Disturbance | Streptococcal Pneumonia

Netherlands
Centre Oscar Lambret

Unknown

Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome

Breast Cancer | Brain and Central Nervous System Tumors | Metastatic Cancer

France
Karolinska Institutet
Mbarara University of Science and Technology; Science for Life Laboratory; Epicentre... and other collaborators

Completed

Paediatric Infections Point-Of-Care (PI-POC)

Meningitis | Pediatric Infectious Diseases

Uganda
the Jeunes en Neuroradiologie Interventionnelle...
University Hospital, Limoges; Sainte Anne Hospital (Paris)

Not yet recruiting

Neurological Complication of Infective Endocarditis: A Prospective Multi-site Cohort Study

Endocarditis, Bacterial | Aneurysm, Intracranial Mycotic
Hellenic Institute for the Study of Sepsis
European Commission

Completed

Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System (INCLASS)

Pneumonia | Sepsis | Mortality | Biomarkers | Respiratory Distress Syndrome | Multiple Organ Failure | Gram-Negative Bacteria Infection

Greece, Belgium
GlaxoSmithKline

Terminated

Feasibility Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants at 3, 5 and 11 Months of Age.

Hepatitis B | Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Neisseria Meningitidis | Haemophilus Influenzae Type b

Slovakia
Charles Drew University of Medicine and Science

Not yet recruiting

ACTIVATE in Public Housing

COVID-19 | Pneumonia | Influenza | Meningitis | Vaccine Hesitancy | Varicella Zoster
GlaxoSmithKline
PATH; Iqvia Pty Ltd; AMP (Agence de Médecine Préventive) (in French); RAFT (Réseau... and other collaborators

Completed

A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine

Malaria | Malaria Vaccines

Ghana, Burkina Faso, Kenya
GlaxoSmithKline

Completed

Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants

Hepatitis B | Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Neisseria Meningitidis | Haemophilus Influenzae Type b

Germany, France, Canada
Hôpital Louis Mourier

Completed

Microbial and Pharmacological Assessment of Chlorhexidine

Pneumonia, Ventilator-Associated | Infection, Bacterial | Chlorhexidine | Oropharynx Abnormality | Bacterium; Agent
Laurie Eisenberg
Children's Hospital Los Angeles; Huntington Medical Research Institutes; Keck...

Unknown

A Safety Study of the Auditory Brainstem Implant for Pediatric Profoundly Deaf Patients

Profound Bilateral Deafness Due to | Bilateral Cochlear Aplasia | Bilateral Cochlear Nerve Deficiency | Bilateral Cochlear Ossification Secondary to Meningitis

United States
University of California, San Francisco
University of California, Berkeley; University of California, Los Angeles; Children... and other collaborators

Completed

Precision Diagnosis of Acute Infectious Diseases; Neuroinflammatory Cohort (PDAID)

Encephalitis | Meningitis

United States
Laboratoires Thea

Completed

Clinical Efficacy and Safety of T1225 Versus Tobramycin 0.3 % Eye Drops in the Treatment of Purulent Bacterial Conjunctivitis of Children.

Purulent Bacterial Conjunctivitis

France
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
GlaxoSmithKline
Biomedical Advanced Research and Development Authority

Completed

Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Relative Bioavailability Study in Healthy Subjects (PDF112034)

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Repeat Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Subjects

Infections, Bacterial

Australia
Guangzhou Center for Disease Control and Prevention

Unknown

Early Waning of Maternal Measles and Meningitis C Antibodies (EWMM)

Measles

China
GlaxoSmithKline

Completed

Pharmacokinetics of Gepotidacin Tablets in Adults and Adolescents Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Three-part Study to Determine the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Volunteers and Healthy Male Japanese Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Amoxicillin Bioequivalence Study Brazil - Fast

Infections, Bacterial

Brazil
GlaxoSmithKline

Withdrawn

A Pharmacokinetics, Pharmacodynamics, and Safety Study of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol When Co-administered With GSK1322322 in Healthy Adult Women

Infections, Bacterial
Sir Run Run Shaw Hospital
University of Birmingham

Unknown

Gram-negative Bacilli and MRSA Screening in ICU in China

Infections, Bacterial

China
GlaxoSmithKline

Completed

Relative Bioavailability, Safety, Tolerability, Pharmacokinetics (PK) and Food Effect Study of GSK2140944 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Randomized, Single Blind, Placebo Controlled Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses and Repeat Escalating Oral Doses of GSK2251052 in Healthy Adult Subjects

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Single Dose Escalation First Time in Human PK Study

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Oral and Intravenous GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Study to Assess the Relative Bioavailability of Three Formulations and Food Effect on GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Retapamulin Ointment in Healthy Adults Nasally Colonized With Staphylococcus Aureus

Infections, Bacterial

United States

Clinical Trials on Meningitis, Bacterial

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