Clinical Trials on Mucopolysaccharidosis III

Total 4578 results

University of Illinois at Chicago
National Institute of Mental Health (NIMH)

Recruiting

Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK) (UnMASCK)

Mood Disorders | Major Depressive Disorder | Bipolar Disorder I | Bipolar Disorder II | Persistent Depressive Disorder (Dysthymia) | Cyclothymia

United States
Laval University
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie... and other collaborators

Active, not recruiting

Diet Quality and Coronary Artery Calcification in Adults With Heterozygous Familial Hypercholesterolemia (FH-CAC)

Diet Habit | Hypercholesterolemia, Familial | Calcification; Heart

Canada
Riphah International University

Completed

Effects of Moderate Physical Activity on Early Symptoms of Peripheral Diabetic Neuropathy in Type-II Diabetes: A Randomized Clinical Trial

Peripheral Diabetic Neuropathy

Pakistan
Jair Bar, M.D., Ph.D.
Merck Sharp & Dohme LLC

Completed

Anti PD-1 Neo-adjuvant Treatment for NSCLC (MK3475-223)

Non Small Cell Lung Carcinoma | Stage II | Stage I

Israel
University Hospital, Strasbourg, France

Terminated

Determination of Genetic Susceptibility in Severe Recurrences of Ocular Toxoplasmosis (TREXO)

Toxoplasmosis Infection | Genotype II | Ocular Toxoplasmosis With Recurrences

France
Stanford University

Completed

B-mode Ultrasound Imaging in Detecting Early Liver Cancer

Fibrosis | Cirrhosis | Stage I Hepatocellular Carcinoma | Stage II Hepatocellular Carcinoma | Early Hepatocellular Carcinoma

United States
National Taiwan University Hospital

Completed

The Analysis of Heart Rate Variability With 24hrs Holter ECG and Serum Cardiac Fibrosis Markers in Critical Illness Patients Who Are With Cardiogenic Shock, With ECMO or IABP Support, or With APACH II Score >25)

Cardiogenic Shock, | With ECMO or IABP Support, | With APACH II Score >25)

Taiwan
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Stage 0 Chronic Lymphocytic Leukemia | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Ann Arbor Stage I Small Lymphocytic Lymphoma | Ann Arbor Stage II Small Lymphocytic Lymphoma | Chronic Lymphocytic Leukemia... and other conditions

United States
National Cancer Institute (NCI)

Completed

Suberoylanilide Hydroxamic Acid in Treating Patients With Metastatic and/or Locally Advanced or Locally Recurrent Thyroid Cancer

Insular Thyroid Cancer | Recurrent Thyroid Cancer | Stage II Follicular Thyroid Cancer | Stage II Papillary Thyroid Cancer | Stage IV Follicular Thyroid Cancer | Stage IV Papillary Thyroid Cancer | Thyroid Gland Medullary Carcinoma

United States
University of Washington
National Cancer Institute (NCI)

Terminated

Nivolumab and Plinabulin in Treating Patients With Stage IIIB-IV, Recurrent, or Metastatic Non-small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | EGFR Activating Mutation | Stage IV Non-Small Cell Lung Cancer AJCC v7 | ALK Gene Translocation | Stage IIIB Non-Small Cell Lung Cancer AJCC v7 | ROS1 Gene Translocation

United States
National Cancer Institute (NCI)

Completed

Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors

Stage IV Ovarian Germ Cell Tumor | Recurrent Ovarian Germ Cell Tumor | Stage III Testicular Cancer | Recurrent Malignant Testicular Germ Cell Tumor | Recurrent Extragonadal Seminoma | Recurrent Malignant Extragonadal Germ Cell Tumor | Recurrent Malignant Extragonadal Non-Seminomatous Germ Cell... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial

Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Ovarian Serous Adenocarcinoma | Primary Peritoneal Serous Adenocarcinoma | Primary Peritoneal Clear... and other conditions

United States
University of Padova

Completed

Factor XIII and Other Biomarkers in ST Segment Elevation Myocardial Infarction (eXIST)

Coronary Microvascular Disease | Factor XIII Deficiency | ST-Elevation Myocardial Infarction | Myocardial Haemorrhage

Italy
University of Washington
National Cancer Institute (NCI)

Completed

Imatinib Mesylate and Paclitaxel in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Malignant Pleural Effusion

United States
Peregrine Pharmaceuticals

Completed

Phase 3 Study of Bavituximab Plus Docetaxel Versus Docetaxel Alone in Patients With Late-stage Non-squamous Non-small-cell Lung Cancer (SUNRISE)

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Non-Small-Cell Lung Carcinoma | Non-Small-Cell Lung Cancer Stage IIIB | Non-Small-Cell Lung Cancer Stage IV | Non-Small-Cell Lung Cancer Metastatic

United States, Australia, Belgium, France, Germany, Greece, Hungary, Italy, Korea, Republic of, Romania, Russian Federation, Spain, Taiwan, Ukraine
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine, Paclitaxel, Doxorubicin in Metastatic or Unresectable Bladder Cancer With Decreased Kidney Function

Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Regional Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional... and other conditions

United States
Federico II University
Azienda Ospedaliera Città della Salute e della Scienza di Torino; Fondazione... and other collaborators

Recruiting

Characterization of Different Phenotypes of Microvascular Dysfunction and Their Impact on Angina Severity in Patients With Chronic Angina in the Absence of Obstructive Coronary Artery Disease. (MiVa)

Angina CCS Classe II-IV - IMR, RFR, FFR,CFR

Italy
Laval University
Université de Montréal; Centre de Recheche du Centre Hospitalier Université...

Recruiting

Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia. (FH-Diet)

Cardiovascular Diseases | Familial Hypercholesterolemia | Cholesterol, Elevated | Nutrition, Healthy | Cholesterol; Metabolic Disorder

Canada
NewAmsterdam Pharma

Active, not recruiting

Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies. (BROOKLYN)

Dyslipidemias | Hypercholesterolemia | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Familial Hypercholesterolemia | Metabolic Disease | High Cholesterol | Genetic Disease, Inborn | Lipid Metabolism Disorder

United States, Canada, Czechia, Georgia, Netherlands, Norway, Poland, South Africa, Spain, United Kingdom
Johns Hopkins University
Beth Israel Deaconess Medical Center

Active, not recruiting

Dietary Approaches to Stop Hypertension for Diabetes (DASH4D)

Hypertension | Diabetes Mellitus, Type 2 | Diabetes | Diabetes type2 | Type 2 Diabetes | Type2 Diabetes | Type II Diabetes | High Blood Pressure

United States
Muhimbili University of Health and Allied Sciences

Completed

Integrated Hypertension and Diabetes Mellitus Type II Treatment and Care Among People Living With HIV/AIDS

HIV Infections | Hypertension | Diabetes Mellitus

Tanzania
Karolinska Institutet

Enrolling by invitation

Evaluation of a Digiphysical Screening Method to Identify and Diagnose Familial Hypercholesterolemia (DigiLipids)

Hypercholesterolemia | Familial Hypercholesterolemia

Sweden
Organon and Co

Completed

Vytorin Reexamination Study (0653A-174)

Primary Hypercholesterolemia and Homozygous Familial Hypercholesterolemia (HoFH)
REGENXBIO Inc.

Completed

Identifying and Genotyping Homozygous Familial Hypercholesterolemia (HoFH) Patients

Homozygous Familial Hypercholesterolemia (HoFH)

United States
Washington University School of Medicine

Completed

A Phase I/II Trial of Stereotactic Body Radiation Therapy (SBRT)

Inoperable Stage I/II Non-small Cell Lung Cancer

United States
City of Hope Medical Center

Terminated

ED Recovery in Men Age </=65 Treated With Bilateral Nerve Sparing Robotic Assisted Prostatectomy for Prostate Cancer

Prostate Cancer | Stage I Prostate Cancer | Stage II Prostate Cancer | Male Erectile Disorder

United States
National Taiwan University Hospital

Unknown

A Registration Study for Familial Hypercholesterolemia in Taiwan

Familial Hypercholesterolemia

Taiwan
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Urinary Diversion During Robotic Assisted Radical Cystectomy in Patients With Bladder Cancer

Recurrent Bladder Cancer | Urinary Complications | Stage 0 Bladder Cancer | Stage I Bladder Cancer | Stage II Bladder Cancer
Prima BioMed Ltd

Withdrawn

Cvac as Maintenance Treatment Patients With Resected Stage I or Stage II Adenocarcinoma (Cancer) of the Pancreas

Pancreatic Carcinoma Stage I | Pancreatic Carcinoma Stage II
Chang Gung Memorial Hospital

Completed

Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic Nephropathy

Diabetic Nephropathies | Diabetes Mellitus, Type II

China
Shahid Beheshti University of Medical Sciences

Unknown

Effect of the Innovated Seifi's Functional Appliance on Skeletal and Dentoalveolar Changes of Class II/ 1, Deep Bite (Seifi-Fx)

Malocclusion, Angle Class II | Orthodontic Appliance Design | Retrognathism | Deepbite

Iran, Islamic Republic of
Advaxis, Inc.

Completed

Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer

Effects of Immunotherapy | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Cervical Small Cell Carcinoma | Stage III Cervical Cancer | Stage IVA Cervical Cancer | Stage IVB Cervical Cancer | Metastatic/Recurrent Cervical Cancer | Cervical Adenosquamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Refractory Non-Hodgkin Lymphoma | Refractory Primary Central Nervous System Neoplasm | Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma and other conditions

United States, Puerto Rico
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Polyglutamate Paclitaxel and Carboplatin in Treating Patients With Ovarian Epithelial, Peritoneal, or Fallopian Tube Cancer

Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma | Malignant Ovarian Mixed Epithelial Tumor | Ovarian Brenner Tumor | Ovarian Mucinous Cystadenocarcinoma | Undifferentiated Ovarian... and other conditions

United States
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Patients With Advanced Urinary Tract Cancer

Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Regional Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional... and other conditions

United States
Children's Hospital of Philadelphia
Illumina, Inc.

Active, not recruiting

LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies

Mucopolysaccharidoses | Leukodystrophy | Adrenoleukodystrophy | Adrenomyeloneuropathy | X-linked Adrenoleukodystrophy | Gangliosidoses | Metachromatic Leukodystrophy | Krabbe Disease | Refsum Disease | Cadasil | Sjogren-Larsson Syndrome | Allan-Herndon-Dudley Syndrome | White Matter Disease | GM2 Gangliosidosis | Zellweger... and other conditions

United States
Quovadis Associazione

Recruiting

Physiological Ventricular Pacing Vs Managed Ventricular Pacing for Persistent AF Prevention in Prolonged AV Interval (PhysioVP-AF)

Sinus Node Disease | Atrioventricular; Block, Second Degree (Types I and II)

Italy
Ankara Etlik City Hospital

Completed

The Impact of Neoadjuvant Chemotherapy on Survival Outcomes in Patients With Variant Histologies Bladder Cancer Who Underwent Radical Cystectomy

Bladder Cancer | Bladder Cancer Stage I | Bladder Cancer Stage II

Turkey
REGENXBIO Inc.

Active, not recruiting

A Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501

Homozygous Familial Hypercholesterolemia (HoFH)

United States, Canada, Netherlands
Karo Bio AB

Terminated

Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of Care (AKKA)

Heterozygous Familial Hypercholesterolaemia
Sanjiv Sam Gambhir
National Cancer Institute (NCI)

Completed

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Tongue Cancer | Stage... and other conditions

United States
King's College London
South London and Maudsley NHS Foundation Trust

Recruiting

Synaptic Imaging and Network Activity in Treatment Resistant Depression (SIGNATURE)

Depressive Disorder | Mood Disorders | Anhedonia | Bipolar Disorder | Depressive Disorder, Major | Depressive Disorder, Treatment-Resistant | Bipolar Disorder I | Bipolar Disorder II

United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Intermediate Grade Prostate Cancer

Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8

United States
BioXcel Therapeutics Inc
Cognitive Research Corporation

Recruiting

Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder

Schizophrenia | Bipolar Disorder I | Schizo-Affective Disorder | Schizophreniform; Schizophrenic | Bipolar Disorder II

United States
University of Campinas, Brazil

Completed

EXpanded Combination of Evolocumab Plus Empagliflozin on Diabetes: EXCEED-BHS3 Trial (EXCEED-BHS3)

Diabetes Mellitus, Type 2 | Dyslipidemia Associated With Type II Diabetes Mellitus | Hypertension Arterial

Brazil
Bayer

Completed

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY1142524 in Patients With Type II Diabetes and a Clinical Diagnosis of Diabetic Kidney Disease (CADA DIA)

Diabetic Kidney Disease

Spain, Denmark, Bulgaria, Israel, Sweden, Finland, Italy
University of Minnesota
Brown University; Hennepin County Medical Center, Minneapolis

Completed

Treating Smokers With Mental Illness

Psychotic Disorders | Smoking Cessation | Schizophrenia | Major Depressive Disorder | Mental Illness | Cigarette Smoking | Bipolar Disorder I | Bipolar II Disorder

United States
Jordan University of Science and Technology

Completed

Mild Intraoperative Hyperventilation to Decrease Post-op. Shoulder Pain After LSG

Laparoscopic Gastric Sleeve Surgery | ASA-I and II Risk Class Patients | Same Surgeon

Jordan
Nij Smellinghe Hosptial

Completed

Study the Usefulness of Bio-impedance Spectroscopy in the Early Assessment of Breast Cancer Related Lymphoedema

Lymphedema | Breast Cancer Stage II | Early Disease Onset

Netherlands
Institute of Cardiometabolism and Nutrition, France
Amgen

Unknown

MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR) (CHOLCOEUR)

Familial Hypercholesterolemia - Heterozygous

France

Clinical Trials on Mucopolysaccharidosis III

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Equatorial Guinea

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations