Clinical Trials on Muscle Hypotonia

Total 3717 results

University of Missouri-Columbia

Terminated

Bilateral Versus Unilateral Task Retraining Using the SaeboFlex Orthosis

Muscle Spasticity

United States
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Changes in Echogenicity and Muscle Stiffness in Elastography After Botulinum Toxin Injection a Spastic Muscle

Stroke

France
Daewoong Pharmaceutical Co. LTD.

Completed

A Randomized, Double Blind, Multi-center, Active Drug Controlled, Phase III Clinical Trial to Compare the Safety and Efficacy of DWP450 Versus Botox® in Treatment of Post Stroke Upper Limb Spasticity

Stroke | Spasticity

Korea, Republic of
Cliniques universitaires Saint-Luc- Université...

Recruiting

Effectiveness of Shock Wave Therapy for Upper Limb Spasticity

Stroke

Belgium
The University of Texas Health Science Center,...
University of Houston

Completed

Imaging of 3D Innervation Zone Distribution in Spastic Muscles From High-density Surface EMG Recordings

Spasticity

United States
National Rehabilitation Center, Seoul, Korea

Unknown

Upper Extremity Rehabilitation Using Robot and Botulinum Toxin

Stroke | Spasticity

Korea, Republic of
Medical University of Vienna

Completed

Skeletal Muscle Paralysis in Hypothermic Patients After Cardiac Arrest (RELAX)

Hypothermia | Cardiac Arrest With Successful Resuscitation | Skeletal Muscle Relaxant Overdose

Austria
William Carey University
American Osteopathic Association

Active, not recruiting

Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI

Quality of Life | Pain | Spasticity, Muscle

United States
Guadarrama Hospital
University of San Jorge

Completed

Dry Needling in Stroke to Improve the Upper Limb Functionality

Quality of Life | Spasticity, Muscle | Functionality

Spain
Charles University, Czech Republic

Completed

Reactibility of Muscle Volume to Ribs Mobilization According to Mojžíšová

Muscle Hypertonia | Rib Syndrome

Czechia
Centre Hospitalier Universitaire de Nīmes

Completed

Variability of the Unique Fiber Potentials of a Spastic Muscle Treated With Botulinum Toxin (JITTOX)

Stroke Patient

France
Vanderbilt University
Medtronic

Completed

Intrathecal (IT) Baclofen Drug Distribution (ITB)

Muscle Spasticity

United States
Ipsen

Completed

Study on the Use of Botulinum Toxin Type A in the Treatment of Chronic Post-stroke Spastic Patients (B-CAUSE)

Spasticity

Brazil
University Hospital, Clermont-Ferrand
Centre Hospitalier Universitaire de Saint Etienne; Centre Hospitalier Universitaire... and other collaborators

Unknown

HEMITOX : Effect of Botulinum Toxin Injections on Motor and Functional Ability of Upper Limb in Adults at Earlier Phases of Spastic Hemiplegia After Stroke

Hemiplegia

France
GlaxoSmithKline

Completed

Special Drug Use Investigation for Botox® (Botulinum) Spasticity (BOTOX is a Registered Trademark of Allergan, Inc.)

Mumps
Université du Québec à Chicoutimi
McGill University; Université de Sherbrooke; University of Alberta; University... and other collaborators

Not yet recruiting

Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias

SPG7 | ARSACS

Canada
Wan-Jin Chen

Recruiting

A Registered Cohort Study on Spastic Paraplegia

Spastic Paraplegia

China
Codman & Shurtleff

Terminated

Long-term Surveillance of the MedStream Programmable Infusion System

Spasticity

United States
MedtronicNeuro

Completed

SISTERS: Spasticity In Stroke Study - Randomized Study (SISTERS)

Severe Spasticity

Belgium, Spain, United States, Austria, Germany, Italy, Netherlands, Slovenia, United Kingdom
Fundació Institut de Recerca de l'Hospital de la...

Not yet recruiting

Valuation of the Evolution of Passive Mobility in the Spastic Upper Limb After Injection of Abobotulinumtoxin(Dysport®) (ROM-ICTUS)

Movement Disorders | Spasticity, Muscle | Stroke Sequelae

Spain
Mahidol University

Completed

0.6 vs. 1.2 mg Atropine Together With Neostigmine 2.5 mg on Heart Rate in Patient Receiving Muscle Relaxant

Bradycardia | Neostigmine Adverse Reaction | Adverse Reaction to Belladonna or Atropine
Ipsen

Recruiting

A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity. (LANTIMA)

Spasticity

United States, Spain, Austria, Czechia, Germany, Poland, Russian Federation, Hungary, Bulgaria
Merz Therapeutics GmbH

Completed

Validity and Inter-rater Reliability for Early Recognition of Spasticity Using the Decision Tree Tool (I-REFER)

Post-stroke Spasticity

Austria
AbbVie

Active, not recruiting

Study of Intramuscular Injections of ABBV-950 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Spasticity

Upper Limb Spasticity

United States
Ipsen

Completed

RELIEF Study: Lower Limb Pain Relief After Injection Cycles in Adults Suffering From Lower Limb Spasticity Following Stroke (RELIEF)

Lower Limb Spasticity

Spain
Cancer Institute and Hospital, Chinese Academy...

Unknown

Hemodynamic Changes During Dry Cupping Therapy on Low Back Pain

Muscle Spasticity | Oxygen Metabolism
JoAnn Harnar
Allergan

Completed

Efficacy and Safety Study of Botulinum Neurotoxin A With Rehabilitation Versus Botulinum Neurotoxin A Alone in Treatment of Post-stroke Spasticity

Upper Limb Spasticity

United States
Guadarrama Hospital

Completed

Dry Needling in Stroke in Sub-Acute Phase to Improve Upper Limb

Quality of Life | Spasticity, Muscle | Functionality

Spain
Supernus Pharmaceuticals, Inc.
Solstice Neurosciences

Active, not recruiting

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Lower Limb Spasticity

Spasticity

United States, Czechia
Ipsen

Completed

A Study to Review Treatment Outcomes From Treatment With Dysport® Injections in Adults for Upper and/or Lower Limb Focal Spasticity (DYSCOVER)

Upper and/or Lower Limb Focal Spasticity

United Kingdom
Ipsen

Completed

Relation Between Dose and Time to Reinjection of Botulinum Toxin-A in Patient With Poststroke Spasticity From a Real-world Healthcare Insurance Database. (Relax)

Post Stroke Spasticity

Netherlands
GlaxoSmithKline

Completed

JCP Study of Investigation of Patient Background Characteristics

Spasticity, Post-Stroke
Universidade do Vale do Paraíba

Unknown

Method Pilates X Pilates in Water Postural Alignment and Its Correlation With Respiratory Capacity With Hemiparesis Spastic

Stroke

Brazil
Merck KGaA, Darmstadt, Germany

Completed

An Observational Study to Examine the Patients With Isolated Systolic Hypertonia (ISH) Under Therapy With Eneas® (NIS ENEAS ISH)

Hypertension
Marmara University

Completed

Dynamic Lycra Orthosis as an Adjunct to Botulinum Toxin-A Injection for Post-stroke Spasticity

Stroke | Spasticity as Sequela of Stroke | Upper Limb Hypertonia

Turkey
Eva Ponten

Recruiting

How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery. (CPTDBiopsy)

Cerebral Palsy | Muscle Spasticity | Muscle | Muscle Contracture

Sweden
Eva Ponten

Recruiting

The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies. (CPMuscleSL)

Cerebral Palsy | Spasticity, Muscle | Muscle Contracture

Sweden
Mahidol University

Completed

Efficacy of Intravenous Glyco-P® in Patients Undergoing Procedure That Require Anesthesia Service

Bradycardia | Hypersalivation | Prevention of Drooling | Reversal of Muscle Relaxants

Thailand
University Hospital, Toulouse

Recruiting

Upper-limb Active Function and Botulinum Toxin A (ULAFBoT-Stroke)

Stroke | Muscle Spasticity | Upper Extremity Paralysis

France
The Hospital for Sick Children

Active, not recruiting

Administration of MELPIDA to Determine the Safety and Efficacy for Patients With Spastic Paraplegia Type 50

Spastic Paraplegia Type 50

Canada
Izmir Katip Celebi University

Completed

Inter-rater Reliability of the Australian Spasticity Assessment Scale (ASAS) in Post-stroke Spasticity

Hemiplegia, Spastic

Turkey
Assistance Publique Hopitaux De Marseille

Unknown

Central Effects of Botulinum Toxin: Neurophysiological Study in Stroke Patients With Spastic Lower Limb

Hemiplegic Patients Post-AVC

France
Chang Gung Memorial Hospital

Completed

Wearable Robotic System and Robotic Mirror Therapy in Spastic Hemiplegia Post Botulinum Toxin Injection

Spastic | Hemiplegia, Spastic

Taiwan
Ipsen

Completed

Arm Spasticity - Non-Interventional Study Early BIRD (BoNT Treatment: Initial and Repeated Documentation) (EARLYBIRD)

Post-stroke Arm Spasticity

Germany, Switzerland, Netherlands, Austria, France
University Hospital, Lille

Completed

Impact of Muscular Fatigability on Spastic Co-contractions After Stroke Patients (COCON)

Stroke | Spasticity, Muscle | Gait, Hemiplegic | Muscle Fatigue

France
KK Women's and Children's Hospital
Inerventions AB

Recruiting

Can Transcutaneous Electrical Stimulation Garment Improve Gait in Children With Cerebral Palsy?

Cerebral Palsy | Spasticity, Muscle

Singapore
Ipsen

Terminated

Comparing Lower-concentration Dysport Treatment Targeted to the Neuromuscular Junction With Current Clinical Practice (NMJ)

Arm Spasticity

Sweden, Norway, Denmark, Finland
Ipsen

Terminated

A Prospective, Non-interventional Survey to Evaluate Injection Intervals and Treatment Modalities of Botulinum Toxin A (BoNT-A) in Adult Patients Suffering From Upper Limb Spasticity After Stroke (DECIDE)

Upper Limb Spasticity After Stroke

Belgium
Ipsen

Completed

Dysport® Adult Lower Limb Spasticity Study

Leg Spasticity

United States, Australia, France, Belgium, Czechia, Hungary, Italy, Poland, Portugal, Russian Federation, Slovakia
Mackay Memorial Hospital

Completed

Comparing the Radial Extracorporeal Shock Waves and Botulinum Toxin Injection for Spasticity

Post-Stroke Upper Limb Spasticity

Taiwan

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