Clinical Trials on NRG1 Fusion in Netherlands

Total 61 results

Merus N.V.

Recruiting

A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)

NSCLC Harboring NRG1 Fusion | Solid Tumours Harboring NRG1 Fusion | Pancreatic Cancer Harboring NRG1 Fusion | NRG1 Fusion

Spain, France, Israel, Belgium, Denmark, United States, Korea, Republic of, Japan, Germany, Netherlands, Austria, Canada, Italy, Norway, Singapore, Sweden, Taiwan, United Kingdom
M.C. Kruyt, MD, PhD
Kuros BioSciences B.V.

Active, not recruiting

MagnetOs™ Granules vs. Autograft in Instrumented Posterolateral Spinal Fusion (MaxA)

Spinal Fusion

Netherlands
Rijnstate Hospital

Recruiting

Intercorporal Bone Graft Measurement Study

Spinal Fusion | Spondylolisthesis

Netherlands
Centre Leon Berard

Recruiting

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING) (TRacKING)

Cancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditions

France, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
UMC Utrecht
NuVasive

Completed

RCT of AttraX® Putty vs. Autograft in Instrumented Posterolateral Spinal Fusion (AxA)

Instrumented Spinal Fusion | Spinal Deformity | Spinal Instability

Netherlands
Isala

Recruiting

Evaluating the Safety of Shortened Infusion Times for dIfferent Oncological Immunotherapie (MINUTE)

Oncology | Infusion Reaction

Netherlands
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Evaluation of a Standardised Orientation and Mobility Training in Older Adults With Low Vision

Aged | Low Vision

Netherlands
Ilse van de Wijgert
Radboud University Medical Center

Completed

Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery (RCT-ESPB)

Lumbar Disc Herniation | Lumbar Spinal Stenosis | Fusion of Spine | Spinal Fusion | Lumbar Spondylolisthesis | Spondylolisthesis | Lumbar Disc Disease | Lumbar Spondylosis | Lumbar Spine Disease | Lumbar Radiculitis | Spondylosis Lumbosacral Region

Netherlands
Royal Dutch Visio
Radboud University, Behavioural Science Institute, Nijmegen, The Netherlands

Recruiting

Viewing Strategy Training in Children With (Cerebral) Visual Impairment

Vision Disorders | Vision, Low

Netherlands
Radboud University Medical Center

Terminated

Cediranib as Palliative Treatment in Patients With Symptomatic Malignant Ascites or Pleural Effusion

Malignant Ascites | Malignant Pleural Effusion

Netherlands
St. Antonius Hospital

Completed

Validation of the Western Ontario Rotator Cuff Index in Patients With Arthroscopic Rotator Cuff Repair (WORC)

Disorder of Rotator Cuff | Other Instability, Shoulder | Rotator Cuff Lesion

Netherlands
Maatschap Cardiologie Zwolle
Abbott; Radboudumc Technology Center; Clinical Studies

Recruiting

Use of Physiology to Evaluate Procedural Result After PCI CTO (ULTRA-CTO)

Percutaneous Coronary Revascularisation | Complex Coronary Lesion

Netherlands
Maastricht University Medical Center

Unknown

Arginine and Nitric Oxide (NO) Early Prognostic Markers for Non-union Development

Fracture Healing | Atrophic Non Union Development | Hypertrophic Non Union Development

Netherlands
Onze Lieve Vrouwe Gasthuis
Mayo Clinic; University of New South Wales

Completed

Predicting the Outcome After Treatment of Meniscal Tears

Surveys and Questionnaires | Meniscus Lesion

Netherlands
VU University of Amsterdam

Completed

Effectiveness of the Serious Game 'Broodles' for Siblings of Children With Visual Impairment and/or Intellectual Disability

Healthy

Netherlands
Zuyderland Medisch Centrum

Completed

Long-term Follow-up Motion Analysis of ACD Versus ACDA

Spinal Stenosis | Cervical Radiculopathy | Cervical Myelopathy | Spine Degeneration | Spine Fusion | Spinal Disease

Netherlands
Radboud University Medical Center

Completed

Self-management for Dual Sensory Impaired

Hearing Loss | Low Vision

Netherlands
Amsterdam UMC, location VUmc
Royal Dutch Visio

Not yet recruiting

Gaining Insight Into Dual Sensory Loss (DSL)

Dual Sensory Impairment of Vision and Hearing

Netherlands
UMC Utrecht

Completed

IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee. (IMPACT)

Inflammation | Knee Pain Swelling | Foreign-Body Reaction | Effusion (L) Knee

Netherlands
Erasmus Medical Center

Active, not recruiting

The Effect of Early Glasses on the Development of Amblyopia (EGS)

Refractive Errors | Amblyopia

Netherlands
Erasmus Medical Center
Public Health Service of Amsterdam; Icare Youth Health Care

Completed

Disinvestment Study of Population-Based Vision Screening in Children

Amblyopia

Netherlands
Valérie Schuermans

Recruiting

Cervical Arthroplasty Cost Effectiveness Study (CACES) (CACES)

Cervical Disc Disease | Cervical Fusion | Fusion of Spine | Cervical Spondylosis | Cervical Disc Herniation | Myelopathy Cervical | Cervical Disc Degeneration | Radiculopathy, Cervical | Myelopathy, Compressive | Radiculopathy, Cervical Region | Radiculopathy; in Spondylosis | Radiculopathy; in Intervertebral... and other conditions

Netherlands
Erasmus Medical Center
Lijf & Leven; ODAS Stichting; Uitzicht; University of Applied Sciences Utrecht

Recruiting

Patching or Gaming as Amblyopia Treatment?

Amblyopia

Netherlands
Bayer

Active, not recruiting

A Study to Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumors With NTRK-fusion in Children (SCOUT)

Solid Tumors Harboring NTRK Fusion

United States, China, Poland, Australia, Germany, Japan, Canada, Italy, Czechia, Spain, Turkey, United Kingdom, Sweden, Netherlands, France, Switzerland, Korea, Republic of, Denmark, Ireland, Israel, Ukraine
Cathreine BV
Catharina Ziekenhuis Eindhoven; St. Antonius Hospital; Medical Centre Leeuwarden and other collaborators

Recruiting

Bifurcation PCI With a Hybrid Strategy With Drug Eluting Balloons Versus a Stepwise Provisional Two-stent Strategy (Hybrid DEB)

Coronary Artery Disease | Coronary Bifurcation Lesion

Netherlands
Bone Therapeutics S.A

Terminated

Study on Autologous Osteoblastic Cells Implantation in Hypotrophic Non-Union Fractures

Long Bone Non-Union

Belgium, France, Netherlands
Philips Healthcare

Completed

Optical Detection of Malignancy During Percutaneous Interventions

Breast Cancer | Colon Cancer Liver Metastasis | Pulmonary Coin Lesion

Netherlands
European Cardiovascular Research Center

Active, not recruiting

ABSORB Bioresorbable Scaffold vs. Xience Metallic Stent for Prevention of Restenosis in Patients at High Risk of Restenosis (Compare Absorb)

Coronary Artery Lesion

Italy, Spain, Belgium, Germany, United Kingdom, France, Czechia, Poland, Netherlands
Vedea Healthware BV
Elisabeth-TweeSteden Ziekenhuis; Jeroen Bosch Ziekenhuis; Health Holland; Oogziekenhuis... and other collaborators

Recruiting

Validation of New Virtual Reality Treatment for Children With Lazy Eye Using the Vedea Amblyopia Therapy (VAT) (VAT)

Amblyopia | Amblyopia, Anisometropic | Amblyopia Strabismic

Netherlands
TiGenix n.v.

Completed

RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee (TIGACT01)

Articular Cartilage Lesion of the Femoral Condyle

Belgium, Croatia, Germany, Netherlands
Increase Co., Ltd.
Erasmus Medical Center; Terumo Corporation; Fujita Health University

Unknown

Using 3D Imaging to Optimize Bifurcation Stenting

Coronary Artery Disease | Bifurcation Lesion

Japan, Netherlands
Academisch Ziekenhuis Maastricht
Radboud University Medical Center

Recruiting

Oral Microbioma and Oral Malignant Disease

Oral Cancer | Oral Squamous Cell Carcinoma | Premalignant Lesion

Netherlands
Novartis

Completed

A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study (RESTORE)

Diabetic Macular Edema

Greece, Belgium, Spain, France, Netherlands, Australia, Canada, Germany, Hungary, Italy, Switzerland, Turkey, United Kingdom
UMC Utrecht
Universitaire Ziekenhuizen KU Leuven; Maastricht University Medical Center; Carl...

Completed

The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation (ADVISE)

Vision Disorders | Fuchs Dystrophy | Bullous Keratopathy | Endothelial Corneal Dystrophy

Netherlands, Belgium
University Medical Center Groningen

Not yet recruiting

Perimetry Based on Eye-movements in Patients With (Supra)Sellar Tumors

Pituitary Tumor | Visual Fields Hemianopsia

Netherlands
UMC Utrecht
Isala

Completed

Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis (PRE-FURTHER)

Quality of Life | Pain | Neoplasm Metastasis | Bone Cancer | Bone Metastases | Tumor | Radiation Toxicity | Bone Neoplasm | Bone Lesion | Cancer Induced Bone Pain

Netherlands
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan, United Kingdom
Radboud University Medical Center
Stichting Ushersyndroom

Active, not recruiting

Characterizing Rate of Progression in USHer Syndrome (CRUSH) Study (CRUSH)

Retinitis Pigmentosa | Usher Syndrome, Type 2A | USH2A

Netherlands
Zimmer Biomet

Active, not recruiting

G7 BiSpherical Acetabular Shell PMCF Study

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Femoral Neck Fractures | Trochanteric Fractures | Noninflammatory Degenerative Joint Disease | Correction of Functional Deformity | Non-Union Fracture

Netherlands, France, Germany, Switzerland
CorNeat Vision Ltd.

Recruiting

Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal Blindness

Corneal Opacity | Corneal Disease | Corneal Injuries

France, Canada, Israel, Netherlands
Fondazione Telethon

Unknown

Natural History Study in Subjects With Usher Syndrome

Usher Syndrome, Type 1B

Italy, Netherlands, Spain
UMC Utrecht
Turku University Hospital; University of Bologna; University of Roma La Sapienza and other collaborators

Recruiting

Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases (FURTHER)

Quality of Life | Pain | Neoplasm Metastasis | Bone Cancer | Bone Metastases | Tumor | Bone Neoplasm | Bone Lesion | Cancer Induced Bone Pain

Netherlands, Germany, Finland, Italy
CorNeat Vision Ltd.

Terminated

First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness

Corneal Opacity | Corneal Disease | Corneal Injuries

France, United States, Canada, Netherlands, Israel
Relay Therapeutics, Inc.

Active, not recruiting

REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors

Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Amplification | FGFR2 Gene Fusion/Rearrangement | FGFR2 Gene Translocation | FGFR2 Gene Activation | Other Solid Tumors, Adult

United States, France, Italy, United Kingdom, Korea, Republic of, Spain, Taiwan, Sweden, Germany, Netherlands, Singapore, Australia, Hong Kong
Centre Hospitalier National d'Ophtalmologie des...
Institut National de la Santé Et de la Recherche Médicale, France

Unknown

Clinical and Genetic Examination of Usher Syndrome Patients' Cohort in Europe (EURUSH)

Usher Syndrome

France, Germany, Netherlands, Portugal
QLT Inc.

Completed

Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01)

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

Canada, United States, Germany, Netherlands, United Kingdom
QLT Inc.

Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

United States, Canada, Germany, Netherlands, United Kingdom
Editas Medicine, Inc.

Completed

Natural History Study of CEP290-Related Retinal Degeneration

Eye Diseases | Retinal Degeneration | Eye Diseases, Hereditary | Vision Disorders | Blindness | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

United States, Netherlands, France, Germany
ProQR Therapeutics

Recruiting

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene. (BRIGHTEN)

Eye Diseases | Neurologic Manifestations | Retinal Degeneration | Retinal Dystrophies | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

Belgium, Brazil, Canada, Germany, Italy, Netherlands, United Kingdom
QLT Inc.

Completed

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Leber Congenital Amaurosis (LCA) | Retinitis Pigmentosa (RP)

United States, Canada, Denmark, Germany, Netherlands, Switzerland, United Kingdom

Clinical Trials on NRG1 Fusion in Netherlands

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