Clinical Trials on Neoplasia

Total 107973 results

Stony Brook University

Active, not recruiting

A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies

Parkinson Disease | Multiple System Atrophy | Normal Pressure Hydrocephalus | Rapid Eye Movement Sleep Behavior Disorder

United States
Washington University School of Medicine
Massachusetts General Hospital; Mayo Clinic; McGill University; University of California... and other collaborators

Enrolling by invitation

North American Prodromal Synucleinopathy Consortium (NAPS)

Parkinson Disease | Lewy Body Disease | Multiple System Atrophy | REM Sleep Behavior Disorder | Dementia With Lewy Bodies | REM Sleep Parasomnias

United States, Canada
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs

HIV Infections | Hepatitis B | Measles | Pneumococcal Infections | Pertussis

United States, Puerto Rico
Skane University Hospital
AC Immune SA

Completed

Optimization of Morphomer-based Alpha-synuclein PET Tracers

Parkinson Disease | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Dementia With Lewy Bodies

Sweden
Nestlé
Nestec Ltd.; Regulatory and Clinical Research Institute Inc; Cytel Inc.

Terminated

Videofluoroscopic Swallowing Study (VFSS) (PORSCHE)

Stroke | Multiple Sclerosis | Parkinson Disease | Dementia | Alzheimer Disease | Oropharyngeal Dysphagia

United States, Finland
University Health Network, Toronto

Enrolling by invitation

Decreased Empathy and Emotion Recognition in Patients With Neurodegenerative Disease (Empathy)

Parkinson Disease | Dementia | Alzheimer Disease | Vascular Dementia | Frontotemporal Lobar Degeneration | Neuro-Degenerative Disease | Caregiver Burnout

Canada
Riphah International University

Completed

Providing Speech Therapy Awareness in Private Schools

Head and Neck Cancer | Stuttering | Hearing Impairment | Swallowing Disorder | Speech Therapy | Developmental Delay Disorder | Speech Delay | Speech and Language Disorder | Acquired Language Disorders

Pakistan
University of Minnesota
GE Healthcare

Completed

Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism

Parkinson Disease | Gaucher Disease | Idiopathic Rapid Eye Movement Sleep Disorder

United States
University of Pennsylvania
National Institute on Aging (NIA)

Completed

Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Lewy Body Disease | Dementia, Vascular | Delirium, Dementia, Amnestic, Cognitive Disorders

United States
Francisco Marín Ortuño
Hospital General Universitario Elche; Hospital Universitario San Juan de Alicante

Unknown

Myocardial Affectation in Patients With Fabry Disease Without Phenotypic Manifestation. Diagnostic Value of Biomarkers (FAMY)

Right Ventricular Hypertrophy | Fabry Disease, Cardiac Variant
Fred Hutchinson Cancer Center
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Terminated

huJCAR014 CAR-T Cells in Treating Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Adult Acute Lymphoblastic Leukemia | Refractory Diffuse... and other conditions

United States
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Myelodysplastic Syndrome With Excess Blasts | Adult Acute Monocytic Leukemia | Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 and other conditions

United States, Israel, Peru
National Cancer Institute (NCI)

Active, not recruiting

Veliparib and Temozolomide in Treating Patients With Acute Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Adult Acute... and other conditions

United States
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | Prolymphocytic Leukemia and other conditions

China
National Cancer Institute (NCI)

Completed

Alisertib and Romidepsin in Treating Patients With Relapsed or Refractory B-Cell or T-Cell Lymphomas

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent Mantle Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With... and other conditions

United States
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

Diffuse Large B-Cell Lymphoma | Chronic Lymphocytic Leukemia | Anaplastic Large Cell Lymphoma | Small Lymphocytic Lymphoma | Angioimmunoblastic T-Cell Lymphoma | Hepatosplenic T-Cell Lymphoma | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Aggressive Non-Hodgkin Lymphoma | Enteropathy-Associated... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Anti-ICOS Monoclonal Antibody MEDI-570 in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma Follicular Variant or Angioimmunoblastic T-cell Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Advanced Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Recurrent Mycosis Fungoides | Recurrent Primary Cutaneous... and other conditions

United States, Canada
Chinese PLA General Hospital

Completed

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
The Second Affiliated Hospital of Henan University...
Xuzhou Medical University; Xinqiao Hospital of Chongqing

Unknown

Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma (MatchCART)

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19 (CART19)

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
Massachusetts General Hospital
Johns Hopkins University; BioSensics LLC

Recruiting

A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes

Corticobasal Degeneration | Frontotemporal Dementia | Frontotemporal Lobar Degeneration | Progressive Supranuclear Palsy | CBD | FTD | PSP

United States
Lawson Health Research Institute

Recruiting

Investigating Genetic Status in Patients Presenting to Clinic

Lewy Body Dementia (LBD) | Alzheimer Dementia (AD) | Dementia, Frontotemporal

Canada
Cedars-Sinai Medical Center

Recruiting

MS-ResearchBiomarkerS (MS-ReBS)

Multiple Sclerosis | Clinically Isolated Syndrome | Multiple Sclerosis, Relapsing-Remitting | Healthy Aging | Neurologic Disorder | Neuromyelitis Optica Spectrum Disorders | Radiologically Isolated Syndrome | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive | Neurologic... and other conditions

United States
University Hospitals Coventry and Warwickshire...
University of Warwick

Completed

The Impact of Obstructive Sleep Apnoea in Women With Polycystic Ovary Syndrome.

Polycystic Ovary Syndrome | Obstructive Sleep Apnea

United Kingdom
Centre Hospitalier Universitaire de Besancon
Novartis Pharmaceuticals; National Cancer Institute, France; National Research... and other collaborators

Terminated

Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-Comté (ICE)

Breast Cancer | Ischemic Stroke | Parkinson Disease | Age-related Macular Degeneration | Colorectal Cancer | Alzheimer Disease | Prostate Cancer | Hemorrhagic Stroke | Cardiac Disease

France
Ultragenyx Pharmaceutical Inc

Terminated

Adeno-Associated Virus (AAV) Antibody Study in Subjects OTC Deficiency, GSDIa, and Wilson Disease

Wilson Disease | Ornithine Transcarbamylase Deficiency | Glycogen Storage Disease Type IA

Spain, United Kingdom, Canada, United States, Brazil
TidalSense
National Institute for Health Research, United Kingdom; Innovate UK

Completed

Cardiorespiratory Diagnostic Study (CARES)

Healthy | Bronchiectasis | Anemia | Asthma | Lung Cancer | Interstitial Lung Disease | COPD | Long COVID | Upper Respiratory Disease | Congestive Cardiac Failure

United Kingdom
CuraSen Therapeutics, Inc.

Active, not recruiting

A Study of CST-103 Co-administered With CST-107 in Subjects With Neurodegenerative Disorders (CLIN-011)

Mild Cognitive Impairment, Lewy Body Dementia, Parkinson's Disease Rapid Eye Movement Sleep Behavior Disorder, Parkinson's Disease Dementia

Australia, New Zealand, United Kingdom
West Virginia University

Completed

Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS)

COVID-19 | Acute Respiratory Distress Syndrome

United States
Centre Hospitalier Régional d'Orléans

Completed

Latest Imaging SPECT System Evaluation Phase 1 (LISSE1)

Heart Diseases | Neoplasms | Kidney Diseases | Parathyroid Diseases | Thyroid Diseases | Parkinsonian Disorders | Dementia | Pulmonary Embolism | Rheumatic Disease

France
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Pathogenesis of Compromised Bone Quality and Mechanics in Chronic Kidney Disease

Chronic Kidney Disease | Secondary Hyperparathyroidism | End Stage Kidney Disease | Chronic Kidney Disease Mineral and Bone Disorder | Renal Osteodystrophy

United States
Massachusetts General Hospital
ALS Association

Completed

Electronic-health Application To Measure Outcomes REmotely Clinical Trial (EAT MORE)

Parkinson's Disease | Amyotrophic Lateral Sclerosis | Weight Loss | Cachexia | Huntington's Disease | Neurodegenerative Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi Anemia

Previously Treated Myelodysplastic Syndrome | Fanconi Anemia | de Novo Myelodysplastic Syndrome | Acute Myeloid Leukemia in Remission

United States, Brazil
Chang Gung Memorial Hospital

Completed

18F-PM-PBB3 PET Study in Tauopathy Including Alzheimer's Disease, Other Dementias and Normal Controls

Frontotemporal Dementia | Progressive Supranuclear Palsy | Alzheimer's Disease | Vascular Cognitive Impairment | Cortical Basal Syndrome

Taiwan
Centre Hospitalier Universitaire, Amiens

Terminated

Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies (GREFEXII)

Stroke | Parkinson Disease | Alzheimer Disease | Traumatic Brain Injury | Huntington Disease | Frontal Dementia

France
Assistance Publique - Hôpitaux de Paris
Pr Joel COSTE, Hôpital Hôtel Dieu - Unité de Bio Statistiques et Epidémiologiques...

Completed

Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases (DYSLIM)

COPD (With - Without Rehabilitation) | Diffuse Interstitial Lung Diseases | Pulmonary Arterial Hypertension Primary or Secondary (Post Embolic .....) | Cystic Fibrosis of the Adult

France
Centre Hospitalier Universitaire, Amiens

Completed

Assessment of Social-emotional Functioning in Neurological Diseases (Emotion)

Stroke | Parkinson's Disease | Alzheimer Disease | Huntington Disease | Lewy Body Dementia

France
Thomas Jefferson University
Abbott

Terminated

Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease (VINCA-CKD)

Coronary Artery Disease | Chronic Kidney Disease | Secondary Hyperparathyroidism | Hypovitaminosis D

United States
Wuhan University
Peking University; Pfizer

Unknown

Efficacy and Safety of Ziprasidone to Treat Depressive Symptoms in Patients With Schizophrenia

The Primary Evaluation is the Change From Baseline at End of Study for CDSS Total Scores. | The Secondary Efficacy Evaluations Include: MADRS, PANSS Total Scores and Subscales and Responder Rate; CGI-S and CGI-I Scales. | Safety Evaluations Include: Laboratory Test Abnormalities; BARS... and other conditions
National Cancer Institute (NCI)

Terminated

Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States
University of Chicago

Not yet recruiting

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

Multiple Sclerosis | Obesity | Obesity, Morbid | Obese | Long COVID | Long Covid19 | Acute Leukemia in Remission
Washington University School of Medicine
Massachusetts General Hospital; Mayo Clinic; McGill University; University of California... and other collaborators

Recruiting

North American Prodromal Synucleinopathy Consortium Stage 2 (NAPS2)

Parkinson Disease | Multiple System Atrophy | REM Sleep Behavior Disorder | Dementia With Lewy Bodies | REM Sleep Parasomnias | Lewy Body Dementia

United States, Canada
Xiaoyan Jia

Recruiting

Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients (NGAL)

Chronic Kidney Disease-Mineral and Bone Disorder

China
First Affiliated Hospital of Fujian Medical University

Recruiting

Treatment of Transcranial Alternating Current Stimulation（tACS）on Cerebellar Ataxia

Spinocerebellar Ataxia Type 3 | Multiple System Atrophy-cerebellar Type

China
Capital Medical University

Recruiting

Integrated Diagnosis and Treatment of CKD on Outcomes

Hyperglycemia | Hypertension | Chronic Kidney Diseases | Anemia | Malnutrition | Hyperlipidemias | Chronic Kidney Disease-Mineral and Bone Disorder

China
Brigham and Women's Hospital

Recruiting

Advance Care Planning in the Emergency Department

Chronic Obstructive Pulmonary Disease | Metastatic Cancer | Congestive Heart Failure | Chronic Kidney Disease Requiring Chronic Dialysis

United States
Milton S. Hershey Medical Center
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Inositol Supplementation to Treat PCOS (INSUPP-PCOS) (INSUPP-PCOS)

Polycystic Ovary Syndrome | Hyperandrogenism | Insulin Resistance | Glucose Intolerance | Anovulation | Metabolic Complication

United States
North Sichuan Medical College
University of Glasgow; Afﬁliated Hospital of North Sichuan Medical College; Nanchong...

Completed

Evaluating the Potential of Large Language Models for Respiratory Disease Consultations (EPLLMMRDC)

Pneumonia | Bronchiectasis | Asthma | Pulmonary Fibrosis | Lung Cancer | Tuberculosis | Acute Upper Respiratory Infection | Pulmonary Embolism | Hay Fever | Acute Bronchitis

China
Lawson Health Research Institute
Alexion Pharmaceuticals, Inc.

Active, not recruiting

Paroxysmal Nocturnal Hemoglobinuria in ESUS & ETUS

Transient Ischemic Attack | Paroxysmal Nocturnal Hemoglobinuria | Cerebral Vein Thrombosis | Embolic Stroke of Undetermined Source

Canada

Clinical Trials on Neoplasia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Portugal

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations