Clinical Trials on Neutral Lipid Storage Disease in Switzerland

Total 956 results

University of Zurich

Completed

Pulmonary Involvement in Patients With Fabry Disease

Fabry Disease

Switzerland
Albina Nowak, MD
Swiss National Science Foundation

Recruiting

Effect of Cannabinoids on Pain in Fabry Disease Patients

Pain, Neuropathic

Switzerland
Spital Linth
University of Zurich; National University, Singapore

Unknown

Lipidomics and Functional Analyses of Platelets in Fabry Disease

Fabry Disease

Switzerland
Alexion Pharmaceuticals

Completed

An Observational Study of Patients With Lysosomal Acid Lipase Deficiency/Cholesteryl Ester Storage Disease Phenotype

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD)

United States, United Kingdom, France, Canada, Czech Republic, Italy, Poland, Switzerland
University of Zurich

Completed

Sleepiness and Sleep-disordered Breathing in Fabry Disease. A Prospective Cohort Study.

Fabry Disease

Switzerland
University Children's Hospital, Zurich
Sanofi

Completed

Development of an Assessment Tool for Health-related Quality of Life in Children and Adolescents With Pompe Disease (Pompe_HrQol)

Pompe Disease

Switzerland
University of Lausanne
University of Modena and Reggio Emilia

Completed

Sialic Acid Supplementation in N-Acetylneuraminic Acid Synthase (NANS) Deficiency

N-Acetylneuraminic Acid Storage Disease

Switzerland, Italy
University of Lausanne

Completed

Acute Effect of Fructose on Lipid Metabolism and Gender Differences

Lipid Metabolism

Switzerland
University of Zurich

Completed

Overnight Feeding Study in Glycogen Storage Disease Type 1

Glycogen Storage Disease Type 1 (GSD 1)

Switzerland
Center for Primary Care and Public Health (Unisante)...
Swiss Heart Foundation

Completed

Cascade Genetic Testing of Familial Hypercholesterolemia (CATCH)

Familial Hypercholesterolemia

Switzerland
Novartis

Completed

Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia

Mixed Dyslipidemia | Heterozygous Familial Hypercholesterolemia

Switzerland
Idorsia Pharmaceuticals Ltd.

Completed

Natural History Study for Pediatric Patients With Early Onset of Either GM1 Gangliosidosis, GM2 Gangliosidoses, or Gaucher Disease Type 2 (RETRIEVE)

GM2 Gangliosidosis | GM1 Gangliosidosis | Tay-Sachs Disease | Sandhoff Disease | Gaucher Disease, Type 2 | AB Variant Gangliosidosis GM2

United States, Spain, Germany, Italy, Belgium, Brazil, France, Portugal, Switzerland, United Kingdom
University Hospital Inselspital, Berne
Takeda

Completed

Physiologic Plasticity of Intramyocardial Lipid Storage

Lipid Metabolism

Switzerland
Idorsia Pharmaceuticals Ltd.

Active, not recruiting

A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease

Fabry Disease

United States, United Kingdom, Norway, Germany, Australia, Canada, Spain, Switzerland, Austria, Belgium, France, Netherlands, Poland
Idorsia Pharmaceuticals Ltd.

Completed

Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease (MODIFY)

Fabry Disease

United States, Spain, Belgium, Australia, Austria, Canada, Germany, Ireland, Italy, Netherlands, Norway, Poland, Switzerland, United Kingdom
University Hospital, Basel, Switzerland

Completed

Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism

Metabolic Syndrome | Familial Combined Hyperlipidemia | Familial Hypertriglyceridemia

Switzerland
Centre Hospitalier Universitaire Vaudois
Agroscope Liebefeld-Posieux Research Station ALP

Completed

Effects of a Probiotics on the Health of Normal Young Males (FFF)

Inflammation | Dyslipidemia

Switzerland
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function (BALANCE)

Fabry Disease

United States, Netherlands, Hungary, United Kingdom, Czechia, Norway, Slovenia, Spain, Finland, France, Italy, Switzerland
KemPharm Denmark A/S

Completed

A Prospective Non-therapeutic Study in Patients Diagnosed With Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

Spain, France, United Kingdom, Switzerland, Denmark, Poland, Italy, Germany
Centre Hospitalier du Centre du Valais
University of Lausanne Hospitals; Research Unit CHCVs Hôpital de Sion Switzerland and other collaborators

Unknown

Effects of High Cut-off (HCO) Hemodialysis on Central Memory CD4+ T and Treg Cells in Patients With End-stage Kidney Disease

End-stage Kidney Disease | CD4 T Cells | Central Memory T Cells | Regulatory T Cells | Uremic Toxins

Switzerland
University of Lausanne
University Hospital Inselspital, Berne; Centre Hospitalier Universitaire Vaudois

Completed

Reduction of Sweetened Beverages and Intrahepatic Fat (REDUCS)

Obesity | Metabolic Syndrome | Dyslipidemia

Switzerland
Novartis

Completed

A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and Hypercholesterolemia

Hypercholesterolemia | Essential Hypertension

Switzerland, Germany
IntraBio Inc

Active, not recruiting

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, Slovakia, Netherlands, Czechia, Switzerland
University of Basel
University of Lausanne; Technical University of Munich

Recruiting

Reducing Circulating Sphingolipid Levels to Optimise Cardiometabolic Health - The SphingoFIT Trial (SphingoFIT)

Cardiovascular Diseases | Dyslipidemias | Blood Pressure | Overweight and Obesity | Metabolic Disease

Switzerland
Novartis

Completed

Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic Syndrome

Dyslipidemia

Germany, Switzerland
ZevraDenmark

Active, not recruiting

Arimoclomol Prospective Study in Participants Diagnosed With Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

United States, Spain, United Kingdom, Denmark, France, Germany, Italy, Poland, Switzerland
Alain Kaelin
Clinical Trial Unit Ente Ospedaliero Cantonale

Recruiting

Effect of Safinamide on Sleep Quality in Patients With Parkinson's Disease

Idiopathic Parkinson's Disease (at Later Stage)

Switzerland
University Hospital Inselspital, Berne

Terminated

The Influence of Different Hydrocortisone Replacement Doses on the Partitioning and Flexibility of Ectopic Lipids in Patients With Corticotropic Hypopituitarism (Hydrocort)

Hypopituitarism | Insulin Sensitivity | Hydrocortisone | Lipids | Fatty Acids, Nonesterified

Switzerland
Genzyme, a Sanofi Company

Recruiting

International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

Gaucher Disease | Cerebroside Lipidosis Syndrome | Glucocerebrosidase Deficiency Disease | Glucosylceramide Beta-Glucosidase Deficiency Disease

Hungary, Croatia, United States, Australia, Belgium, Brazil, Bulgaria, Canada, Denmark, Germany, Greece, Hong Kong, India, Indonesia, Italy, Jordan, Korea, Republic of, Kuwait, Lebanon, Malaysia, Pakistan, Philippines, Poland, Saudi Arabia and more
Sanofi

Recruiting

A Study to Evaluate the Effect of Venglustat Tablets on Neuropathic and Abdominal Pain in Male and Female Participants ≥16 Years of Age With Fabry Disease (PERIDOT)

Fabry Disease

China, Finland, Germany, Norway, United Kingdom, United States, Denmark, Austria, Greece, Romania, Argentina, Brazil, Canada, Japan, Mexico, Poland, Italy, France, Turkey, Australia, Switzerland
University of Zurich
University Ghent; University Hospital of Sao Paulo, Brazil

Completed

Conditioning With Volatile Anesthetics in Liver Transplantation

End-stage Liver Disease

Switzerland
Mandos LLC

Terminated

Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Turkey, Switzerland, Germany, New Zealand, Singapore, France
University of Lausanne Hospitals
Salk Institute for Biological Studies

Completed

Study of Eating Patterns With a Smartphone App and the Effects of Time Restricted Feeding in the Metabolic Syndrome

Obesity | Metabolic Syndrome | Dyslipidemias | Glucose Intolerance | Eating Behavior | Steatosis of Liver

Switzerland
Clarunis - Universitäres Bauchzentrum Basel

Recruiting

Different Limb Lengths in Gastric Bypass Surgery (SLIM)

Hypertension | Diabetes Mellitus, Type 2 | Dyslipidemias | Sleep Apnea | Obesity, Morbid

Switzerland
Cendres+Métaux

Terminated

BONE ANCHORED PORT for Hemodialysis Treatment (BAP)

Hemodialysis Access Failure (Disorder) | End-Stage Renal Disease Requiring Haemodialysis

Switzerland
University of Zurich

Completed

Transoesophageal Echocardiography in Liver Transplantation

End Stage Liver Disease

Switzerland
Foundation for Cardiovascular Research, Zurich
Bristol-Myers Squibb

Completed

Effect of Atazanavir on Endothelial Function in HIV-Infected Patients (ENDOPACT)

HIV Infections | Dyslipidemia

Switzerland
University Hospital Inselspital, Berne
Swiss National Science Foundation

Completed

The Effect of Dietary Fat Load and Physical Exercise on the Flexibility and Partitioning of Ectopic Lipids.

Growth Hormone Deficiency | Insulin Sensitivity | Aerobic Exercise | Ectopic Lipids | Fat Load

Switzerland
Genzyme, a Sanofi Company

Completed

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease (COMET)

Glycogen Storage Disease Type II;Pompe's Disease

Czechia, Taiwan, Belgium, Germany, Korea, Republic of, United States, Argentina, Australia, Austria, Brazil, Canada, Denmark, France, Hungary, Italy, Japan, Mexico, Netherlands, Poland, Portugal, Russian Federation, Spain, Switzerland, Turk... and more
Zemp Damiano
Ente Ospedaliero Cantonale, Bellinzona; ETH Zurich

Completed

Feasibility of an Interactive Tablet-based Exercise Program for People With Chronical Diseases (TABEX-CD)

End Stage Renal Disease

Switzerland
University of Zurich

Recruiting

Intrathecal Double Checkpoint Inhibition (IT-IO)

Melanoma Stage IV | Leptomeningeal Metastasis | Non-small Cell Lung Cancer Stage IV

Switzerland
University Hospital Inselspital, Berne

Terminated

Daptomycin in Pediatric Patients With Bacterial Meningitis

Meningitis

Switzerland
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Swiss Study With Atorvastatin in Hyperlipidemic Patients Measuring LDL-Cholesterol (ACTFAST SWISS)

Hyperlipidemia

Switzerland
University Hospital Inselspital, Berne

Completed

Pilot Study to Investigate the Effects of Increased Dialysate Magnesium and Dialysate Bicarbonate on the Calcification Propensity of Serum (BicMag)

End Stage Renal Failure on Dialysis | Vascular Calcification

Switzerland
Sarah Schiebler
University of Zurich

Recruiting

Effectiveness of Acceptance Commitment Therapy or Micro Breaks in Patients With Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis

Fatigue Syndrome, Chronic

Switzerland
Cantonal Hospital of St. Gallen

Completed

Recurrence and Patient Satisfaction After Laparoscopic Hernia Repair With Intraperitoneal Onlay-mesh (IPOM) (SGChirIPOM)

Ventral Hernia | Recurrent Ventral Hernia

Switzerland
University Hospital Inselspital, Berne
Rigshospitalet, Copenhagen, Denmark (Prof. Moller, Dr. Krag)

Completed

Sup-Icu RENal (SIREN) (SIREN)

Critical Illness | Acute Kidney Injury | Renal Replacement Therapy | End-stage Renal Disease | Proton Pump Inhibitor

Denmark, Switzerland
PD Dr. Grégoire Wuerzner
University Hospital, Geneva; Central Hospital, Nancy, France; Universitair Ziekenhuis... and other collaborators

Completed

Blood Pressure Measurement in Dialysed Patients (DIALBP)

End Stage Renal Disease

Switzerland
University Hospital, Basel, Switzerland

Completed

Non-invasive Assessments of Central Venous Pressure

Ultrasonic Diagnosis | Venous Pressure, Central

Switzerland
European Organisation for Research and Treatment...

Unknown

Radiation Therapy in Treating Patients Who Have Undergone Surgery for Newly Diagnosed Grade II or Grade III Meningioma

Brain and Central Nervous System Tumors

Switzerland

Clinical Trials on Neutral Lipid Storage Disease in Switzerland

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CROs in Malta

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