Transoesophageal Echocardiography in Liver Transplantation
April 9, 2014 updated by: University of Zurich
Transoesophageal Echocardiography in Liver Transplantation: Left Ventricular Function During Reperfusion
Severe hypotension during reperfusion in liver transplantation is a frequent adverse event. Rare data exist so far about pathophysiology of this phenomenon. The exact role of left ventricular function, which might be impaired causing hypotension, has not been elucidated during the period of reperfusion.
Goal of this study is to:
- perform transesophageal echocardiography in order to assess systolic and diastolic left ventricular function during reperfusion
- determine inflammatory mediators in the plasma which could cause left ventricular dysfunction
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Observational
Enrollment (Anticipated)
17
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Zurich, Switzerland
- University Hospital Zurich, Institute for Anesthesiology
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 75 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
Patients on waiting list for liver transplantation
Description
Inclusion criteria:
- Patients on waiting list for liver transplantation.
- Age: 18-75 years.
Exclusion criteria:
- Strictures, tumours and diverticula of the oesophagus.
- History of oesophageal varices with recent bleeding.
- Oesophageal varices and prothrombin time less than 20% or platetlets les than 30000/ml.
- Instable cervical spine.
- Involvement in other studies.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Marco Zalunardo, MD, Universitaetsspital Zuerich
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
April 1, 2006
Primary Completion (Actual)
January 1, 2010
Study Completion (Actual)
January 1, 2010
Study Registration Dates
First Submitted
October 22, 2007
First Submitted That Met QC Criteria
October 22, 2007
First Posted (Estimate)
October 23, 2007
Study Record Updates
Last Update Posted (Estimate)
April 10, 2014
Last Update Submitted That Met QC Criteria
April 9, 2014
Last Verified
April 1, 2014
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- StV 11-2006
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.