Clinical Trials on Nigella Sativa With Beta Thalassemia Major

Total 103 results

HaEmek Medical Center, Israel

Completed

Endocrine and Nutritional Assessment in B Thalassemia Major

Thalassemia

Israel
Cerus Corporation

Completed

Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion

Thalassemia Major

Turkey, Italy
Sun Yat-sen University

Recruiting

The Safety and Efficiency of Luspatercept in Chinese Adults With Transfusion Dependent β-thalassemia: a Real-world Study

Thalassemia Major | Transfusion-dependent Anemia

China
National Taiwan University Hospital

Recruiting

Observing the Changes of Endocrine and Metabolism in Patients With Thalassemia Major

Thalassemia Major

Taiwan
DisperSol Technologies, LLC

Completed

Pilot Study to Assess the Safety, PK and Iron Chelating Activity of DST-0509 (Deferasirox) in Thalassemia Patients Refractory to Chelation

Thalassemia Major

Thailand, United States
Assiut University

Completed

Evaluation of Nutritional Status in Thalassemia Major Patients in Assiut Children Hospital

Thalassemia Major

Egypt
National Human Genome Research Institute (NHGRI)

Completed

Perceptions of Thalassemia Major in Singapore: An Exploratory Study of Stigma

Thalassemia Major

Singapore
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of INC424 in Regularly Transfused Patients With Thalassemia.

Thalassemia Major

Thailand, Turkey, Italy, Lebanon, Greece
First Affiliated Hospital of Guangxi Medical University

Unknown

Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major

Thalassemia Major

China
Nanfang Hospital of Southern Medical University

Unknown

Unrelated Umbilical Cord Blood Following HLA-haploidentical Hematopoietic Stem Cell Transplantation in Patients With β-thalassemia Major

Thalassemia Major

China
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Long Term Outcomes in β Thalassemia Major

Thalassemia Major

United States
Dana-Farber Cancer Institute
Tehran University of Medical Sciences

Completed

Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major

Thalassemia Major

United States, Iran, Islamic Republic of
Weill Medical College of Cornell University

Unknown

The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study

Thalassemia Major

United States
Tanta University

Completed

Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Ain Shams University

Unknown

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Sickle Cell Disease | Beta-thalassemia Major | Iron Hemosiderosis

Egypt
First Affiliated Hospital of Guangxi Medical University
Peking University People's Hospital; Ruijin Hospital; The Affiliated Hospital... and other collaborators

Recruiting

Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study

Thalassemia Major

China
Bioray Laboratories
First Affiliated Hospital of Guangxi Medical University

Suspended

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Thalassemia Major

China
Assiut University

Unknown

Sexual Maturation in β-Thalassemia Major Patients in Assiut University Hospital

β-Thalassemia Major Patients Receiving Chelation Therapy
Fakultas Kedokteran Universitas Indonesia

Completed

Zinc Supplementation on Cellular Immunity in Thalassemia Major

Thalassemia | Immunosuppression | Splenectomy; Status

Indonesia
Paul Szabolcs

Recruiting

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Sickle Cell Anemia | Diamond-blackfan Anemia | Beta-thalassemia Major

United States
UCSF Benioff Children's Hospital Oakland
Novartis Pharmaceuticals

Completed

Reproductive Capacity and Iron Burden in Thalassemia (Fertility thal)

THALASSEMIA MAJOR

United States
Ain Shams University

Unknown

Role of Vitamin C to Augment Iron Chelation With DFP or DFX

Thalassemia Major | Iron Chelation | Vitamin c

Egypt
Timothy Olson

Active, not recruiting

Pilot Study PBSCT With TCRab Depletion For Hemoglobinopathies

Sickle Cell Disease | Thalassemia Major

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Longitudinal Study on the QoL of Pediatric Patients After HSCT and Its Influencing Factors

Acute Leukemia | Thalassemia Major

China
National Institute of Allergy and Infectious Diseases...

Terminated

Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia

Anemia, Sickle Cell | Hemoglobinopathies | Thalassemia | Hemoglobin SC Disease | Thalassemia Major

United States
Ente Ospedaliero Ospedali Galliera
University of Campania "Luigi Vanvitelli"; Reggio Calabria; Ospedale Maggiore... and other collaborators

Completed

Efficacy and Safety of Neridronate (Nerixia®)to Treat Osteoporosis in Patients With TM and TI (Nerixia)

Osteoporosis | Thalassemia Major | Thalassemia Intermedia

Italy
Assiut University

Not yet recruiting

NAC Effect on Iron Overload and Blood Transfusion in β-thalassemia Major

Thalassemia Major
Beni-Suef University

Completed

The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia Major

Thalassemia Major

Egypt
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major (AmloThal)

Iron Overload | Thalassemia

Brazil
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major (AnloThal)

Thalassemia Major

Brazil
Beni-Suef University
University of Arizona; Maternity and Children Hospital, Makkah; Beni-Suef Health...

Completed

Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia

Iron Overload | Oxidative Stress | Thalassemia Major

Egypt, Saudi Arabia
King Saud University

Completed

Periodontal Therapy in Thalassemia Major Patients

Chronic Periodontitis | Thalassemia Major
National Center for Research Resources (NCRR)
Children's Hospital of Philadelphia

Completed

Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia Major

Osteoporosis | Osteopenia | Thalassemia Major
Novartis Pharmaceuticals

Completed

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Transfusional Iron Overload | β-thalassemia Major | Pediatric Rare Anemia

Italy, France
Ersi Voskaridou

Completed

Denosumab vs Placebo in Patients With Thalassemia Major and Osteoporosis

Osteoporosis | Thalassemia Major

Greece
Fakultas Kedokteran Universitas Indonesia

Completed

Pneumococcal Vaccination for Splenectomised Thalassemia Major Patients in Indonesia

Thalassemia | Pneumococcal Infection

Indonesia
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders

Neutropenia | Sickle Cell Anemia | Red-Cell Aplasia, Pure | Thalassemia Major

United States
University Health Network, Toronto

Recruiting

Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation (TICATS)

Thalassemia Major

Canada
ApoPharma

Completed

Efficacy Study in Removing Excess Iron From the Heart

Hemosiderosis | Thalassemia Major

Greece, Italy
University Health Network, Toronto

Completed

MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias (MAFIO)

Thalassemia Major | Chronic Blood Transfusion Related Iron Overload

Canada
Ospedale Microcitemico
Azienda Sanitaria Locale di Cagliari

Completed

Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia Major (DFODFPTM)

Iron Overload | Cardiomyopathy

Italy
Ente Ospedaliero Ospedali Galliera

Completed

Prevalence of Pulmonary Hypertension (PAH) in Patients With Thalassemia (PAH2010)

Pulmonary Arterial Hypertension | Thalassemia Major | Thalassemia Intermedia

Italy
Wolfson Medical Center

Unknown

GDF 15 in Sickle Cell Disease and Hereditary Spherocytosis (GDF 15)

Patients With Thalassemia Intermedia, | Congenital Dyserythropoietic Anemia Type I
Azienda Ospedaliero-Universitaria di Modena

Recruiting

"Iron Overload and Endocrinological Diseases"

Iron Overload | Hemochromatosis | Thalassemia Major | Thalassemia Intermedia | Endocrinopathy

Italy
Boston Children's Hospital
Novartis

Completed

Pilot Study for Patients With Poor Response to Deferasirox

Sickle Cell Disease | Thalassemia Major | Transfusion-dependent Hemachromatosis

United States
University of Milano Bicocca

Completed

Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological Diseases (ThalaCoV)

Covid19 | Thalassemia Major

Italy
Columbia University

Completed

High-Tc Susceptometer to Monitor Transfusional Iron Overload

Myelodysplastic Syndromes | Sickle Cell Disease | Aplastic Anemia | Transfusional Iron Overload | Thalassemia Major

United States
University of Milano Bicocca
Comitato Maria Letizia Verga,Italy

Recruiting

Precision Exercise in Children With Malignant Hemopathies (SportTherapy)

Lymphoma, Non-Hodgkin | Leukemia, Myeloid, Acute | Leukemia, B-cell | Adrenoleukodystrophy | Lymphoma, Hodgkin | Thalassemia Major | Leukemia, T Cell | Drepanocytosis

Italy
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Stem Cell Transplantation (SCT) for Genetic Diseases

Thrombocytopenia | Inborn Errors of Metabolism | Metachromatic Leukodystrophy | Fanconi's Anemia | Thalassemia Major | Pure Red-Cell Aplasia

United States
Emory University

Completed

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Sickle Cell Disease | Fanconi Anemia | Hurler Syndrome | Chronic Granulomatous Disease | Severe Congenital Neutropenia | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Thalassemia Major | Leukocyte... and other conditions

United States

Clinical Trials on Nigella Sativa With Beta Thalassemia Major

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CROs in Dominican Republic

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