Clinical Trials on Oesophageal Adenocarcinoma

Total 13398 results

UMC Utrecht

Completed

Esophagectomy for Patients With Esophageal Cancer and Cervical Lymph Node Metastases (Node)

Adenocarcinoma | Cancer | Squamous Cell Carcinoma | Malignancy

Netherlands
Merck Sharp & Dohme LLC

Active, not recruiting

Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002)

Breast Neoplasms | Colorectal Cancer | Metastatic HER2+ Advanced Breast Cancer | Gastric or Gastroesophageal Junction Adenocarcinoma (GEC)

China
University of Southern California
Sanofi

Completed

Study of Irinotecan and Docetaxel in Patients With Metastatic or Unresectable Gastric or Gastroesophageal Junction Adenocarcinoma

Gastric Cancer | Esophageal Neoplasms

United States
University Hospital, Clermont-Ferrand
Université d'Auvergne; Ligue contre le cancer, France; CRNH Auvergne

Not yet recruiting

Chemotherapy in the Context of Esophageal and Gastroesophageal Junction Cancer Cachexia (CHIFMEOE)

Esophageal Adenocarcinoma

France
University of North Carolina, Chapel Hill
CSA Medical, Inc.

Completed

Prevalence of Dysplasia of the Gastric Cardia

Barrett's Esophagus | Intestinal Metaplasia | Intramucosal Adenocarcinoma

United States
University Hospital, Lille
Groupement Interrégional de Recherche Clinique et d'Innovation; french patient...

Not yet recruiting

Dumping Syndrome and Esophageal Atresia (DUMTORING)

Dumping Syndrome | Oesophageal Atresia

France
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Recruiting

A Phase I Clinical Study of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab Injection in Patients With Advanced Solid Tumors

Liver Cancer, Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma, Cervical Cancer, MSI-H Colorectal Cancer

China
Boston Scientific Corporation

Terminated

Efficacy and Safety of OncoGel™ Added to Chemotherapy and Radiation Before Surgery in Subjects With Esophageal Cancer

Esophageal Cancer | Squamous Cell Carcinoma | Adenocarcinoma of the Esophagus

United States, India, Czechia, Poland
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer

Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant... and other conditions

United States
Mayo Clinic

Terminated

Endoscopic Mucosal Resection and Cellular Matrix

Barretts Esophagus With High Grade Dysplasia | Barrett Adenocarcinoma

United States
Anwaar Saeed
AstraZeneca; Exelixis

Active, not recruiting

Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies (CAMILLA)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Adenocarcinoma

United States
University Hospital, Gasthuisberg

Completed

Signet Ring Cell Carcinoma in Esophageal Adenocarcinoma (SRCC)

Adenocarcinoma | Esophageal Cancer

Belgium
Imperial College London
University College London Hospitals; Northern Care Alliance NHS Foundation... and other collaborators

Recruiting

Non-invasive Testing for Early oEesophageal Cancer and Dysplasia (NEED)

Barrett Esophagus | Oesophageal Cancer | Barretts Esophagus With Dysplasia

United Kingdom
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Massachusetts General Hospital; Guangdong Provincial People's Hospital

Completed

Neoadjuvant Chemotherapy or Chemoradiotherapy in Resectable Oesophageal Carcinoma（NewEC Study）

Chemotherapy Effect | Safety Issues | Radiotherapy Side Effect | Effect of Drugs | Oesophageal Carcinoma

China, United States
University Hospital, Lille

Completed

Dumping Syndrome After Operation of Esophageal Atresia Type III (DUMPING)

Dumping Syndrome | Oesophageal Atresia

France
Arbele Pty Ltd

Recruiting

Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients

Gastric Cancer | Pancreatic Cancer | Cholangiocarcinoma | Esophageal Adenocarcinoma | Gastrointestinal Cancer | Liver Cancer | Colorectal Adenocarcinoma | Gastroesophageal Junction

Hong Kong, Australia
Northern Jiangsu People's Hospital

Completed

A 3-Arm Study Comparing the Efficacy of Anti-Reflux Reconstruction Protocols After Laparoscopic Proximal Gastrectomy

Anti-Reflux Alimentary Reconstruction | Laparoscopic Proximal Gastrectomy | Siewert Type II/III Adenocarcinoma of the Esophagogastric Junction

China
Rigshospitalet, Denmark

Unknown

Study Assessing the Effects of Chemotherapy in Advanced Esophagogastric Adenocarcinoma (SEED)

Stomach Neoplasms | Esophageal Neoplasms

Denmark
Bristol-Myers Squibb
Exelixis

Completed

A Study of BMS-833923 With Cisplatin and Capecitabine in Inoperable, Metastatic Gastric, Gastroesophageal, or Esophageal Adenocarcinomas

Stomach Neoplasms | Esophageal Neoplasms

United States, Canada, France, Netherlands
PharmaEngine

Completed

Study of PEP02, Irinotecan or Docetaxel in Gastric or Gastroesophageal Junction Adenocarcinoma

Stomach Neoplasms | Esophageal Neoplasms

Korea, Republic of, Spain, Taiwan, Bosnia and Herzegovina, United Kingdom, Croatia
Royal Marsden NHS Foundation Trust

Completed

Neoadjuvant Epirubicin, Cisplatin and Capecitabine (ECX) Followed by Definitive Chemoradiation With/Without Surgery for Squamous Cell Carcinoma of the Oesophagus

Oesophageal Carcinoma

United Kingdom
NYU Langone Health

Terminated

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Gastric Cancer | Esophageal Cancer | Gastric Adenocarcinoma

United States
Memorial Sloan Kettering Cancer Center
Sanofi; Genentech, Inc.

Completed

Study of Docetaxel, Cisplatin, and Fluorouracil (Modified DCF) With Bevacizumab in Patients With Unresectable or Metastatic Gastroesophageal Adenocarcinoma

Stomach Neoplasms | Esophageal Neoplasms

United States
Johannes Gutenberg University Mainz

Completed

Safety and Efficacy of Neoadjuvant Radiochemotherapy in Adenocarcinoma of the Gastric-oesophageal Junction

Stomach Neoplasms | Esophageal Neoplasms

Germany
Chiron Corporation

Completed

Tezacitabine With or Without 5-Fluorouracil (5-FU) for Advanced Esophageal Cancer or Gastric Cancer

Adenocarcinoma | Stomach Neoplasms | Esophageal Neoplasms

United States
University Hospital, Angers
Filière des Maladies Rares Abdomino-THOraciques : FIMATHO; Institut de Recherche...

Unknown

Evaluation of the Respiratory Impact After Conventional or Minimally Invasive Esophageal Atresia Surgery (RestriMIS)

Esophageal Atresia | Restrictive Lung Disease | Oesophageal Atresia | Chest Wall Anomaly

France
Astellas Pharma Inc

Completed

A Study of IMAB362 in Japanese Subjects With Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma

Gastric Cancer | Gastro-esophageal Junction (GEJ) Cancer

Japan
Chinese University of Hong Kong

Recruiting

The Microbiome of Oesophageal Squamous Cell Carcinoma

Esophageal Cancer | Microbial Colonization

Hong Kong
I-Mab Biopharma Co. Ltd.

Recruiting

Study of TJ033721 in Subjects With Advanced or Metastatic Solid Tumors

Gastric Cancer | Solid Tumor | Metastatic Cancer | Advanced Cancer | Esophageal Adenocarcinoma | Gastroesophageal Junction Carcinoma

United States, China
Stefania La Grutta, MD

Completed

Study in Children With the Diagnosis of Congenital Diaphragmatic Hernia (CDH) and Oesophageal Atresia (EA) (CDH-EA)

Oesophageal Atresia | Diaphragmatic Hernia
Taipei Veterans General Hospital, Taiwan

Recruiting

Primary Prevention of Patients With Hepatocellular Carcinoma and Concomitant Esophageal Varices (P-HCC)

Hepatocellular Carcinoma | Bleeding Esophageal Varices

Taiwan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer

Peritoneal Carcinomatosis | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma... and other conditions

United States
Anandasabapathy, Sharmila, M.D.
Baylor College of Medicine; William Marsh Rice University

Unknown

Accuracy, Yield and Clinical Impact of a Low-Cost HRME in the Early Diagnosis of Esophageal Adenocarcinoma

Barrett's Esophagus

United States
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal Esophagus

Gastric Cancer | Esophageal Cancer

United States
Massachusetts General Hospital

Completed

Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early Adenocarcinoma

Barrett's Esophagus

United States
University Hospital, Ghent
Universitaire Ziekenhuizen KU Leuven

Recruiting

Barrett's Esophagus and Esophageal Adenocarcinoma, Searching for Reliable Diagnostic RNA Plasma-based Biomarkers

Esophageal Neoplasms

Belgium
GB006, Inc., a wholly owned subsidiary of Gossamer...
Merck Sharp & Dohme LLC

Terminated

GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma

Renal Cell Carcinoma | Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Castration-resistant Prostate Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Esophageal... and other conditions

United States, United Kingdom
Uriach Consumer Healthcare

Recruiting

Efficacy and Speed of Action of a Product to Control Gastric Hydration and Gastroesophageal Reflux (AQUAA)

Oesophageal Reflux | Gastric Reflux | Hyperactivity; Stomach

Spain
Fox Chase Cancer Center
AstraZeneca

Completed

A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery

Cancer of the Esophagus | Adenocarcinoma of the Gastroesophageal Junction | Cancer of the Stomach

United States
Liu Huang

Recruiting

Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer

Stomach Cancer | Breast Cancer | Pancreatic Adenocarcinoma | Lung Cancer | Cholangiocarcinoma | Esophageal Carcinoma

China
OHSU Knight Cancer Institute
Oregon Health and Science University

Completed

Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease | Metaplasia | Barrett Esophagus | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Dysplasia

United States
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Unknown

A Phase 1 Study of ZSP1241 in Participants With Advanced Solid Tumors

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Cholangiocarcinoma

China
Beijing Kejing Biotechnology Co., Ltd.
Beijing Kejing Biotechnology Corp.

Withdrawn

An Exploratory Clinical Study to Evaluate the Safety and Efficacy of NK Cells (Combined With Standard Therapy) in the Treatment of Solid Tumor Patients (CCT-ANK-11)

Solid Tumors (Pancreatic Cancer, Esophageal Cancer, Gastric Cancer, Cholangiocarcinoma, Lung Cancer and Ovarian Cancer)

China
Trans Tasman Radiation Oncology Group
National Health and Medical Research Council, Australia; Canadian Cancer Trials...

Completed

Advanced Oesophageal Cancer Study to Compare Quality of Life and Palliation of Dysphagia.

Esophagus Cancer

Australia, Canada, New Zealand, United Kingdom
Nanchong Central Hospital

Recruiting

Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer

Gastric Cancer | Gastroesophageal Reflux Disease | Proximal Gastric Adenocarcinoma

China
Roswell Park Cancer Institute
Pfizer

Recruiting

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

Advanced Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Clinical Stage III... and other conditions

United States
SOLTI Breast Cancer Research Group
Novartis

Recruiting

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors (ACROPOLI)

Melanoma | Sarcoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Uterine Carcinosarcoma | Mesothelioma | Cholangiocarcinoma | Lung Adenocarcinoma | Triple Negative Breast Cancer | Epithelial Ovarian Cancer | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal... and other conditions

Spain
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Esophageal Cytology With FISH in Detecting Esophageal Cancer

Esophagitis | Weight Loss | Gastroesophageal Reflux Disease | Dysphagia | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Dysplasia | High Grade Dysplasia in Barrett Esophagus

United States
Roswell Park Cancer Institute

Completed

Study To Determine The Maximum Range of Light Doses At Two HPPH Doses With Acceptable Normal Tissue Toxicity For PDT Treatment Of High Grade Dysplasia,CIS or Early Adenocarcinoma In Barrett's Esophagus

Barrett's Esophagus | CIS | HGD

United States
University Hospital Ostrava

Completed

Recurrent Respiratory Papillomatosis and Extraesophageal Reflux

Recurrent Respiratory Papillomatosis | Extra Oesophageal Reflux | Laryngeal Cyst

Czechia

Clinical Trials on Oesophageal Adenocarcinoma

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