Clinical Trials on Operating Tables [E07.325.662]

Total 2114 results

University of California, San Francisco

Completed

Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique

Dysphagia | Hoarseness | Post Operative Sore Throat

United States
Andrea Giaccari

Recruiting

Effects of SGLT2 Inhibition on Myocardial Insulin Sensitivity (DapaHeart)

Type2 Diabetes Mellitus | Stable Coronary Artery Disease

Italy
University of California, San Francisco
Merck Sharp & Dohme LLC

Completed

Pembrolizumab, Capecitabine, and Bevacizumab in Treating Patients With Microsatellite Stable Colorectal Cancer That Is Locally Advanced, Metastatic, or Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Microsatellite Stable | Stage III Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer AJCC v7 | Mismatch Repair Protein Proficient

United States
Yanbing Li

Not yet recruiting

Efficacy and Safety of Chiglitazar Added to Glargine in Patients With Type 2 Diabetes

Efficacy and Safety of Chiglitazar Sodium in the Treatment of T2DM Patients | Metformin Combined With Insulin Glargine in the Treatment of Type 2 Diabetes Patients Who Still Have Poor Hypoglycemic Effect | 128 Patients Were Randomly Assigned 1:1 | Metformin and Insulin Glargine Combined... and other conditions

China
Xiaoping Fan. MD
Jie He.MD; Shihao Cai.MD; Wenda Gu.PhD; Haijiang Guo.PhD; Liang Hong. MD; Ruixing Fan... and other collaborators

Unknown

A Comparative Study of Different Hypothermic Circulatory Arrest Strategies on Aortic Surgery.

Aneurysm | Blood Transfusion | Dialysis | Neurological Disorder | Morality | Endoleak | Operation Time | Hospital Stay | Hypothermic Circulatory Arrest Time | Aortic-cross Clamping Time | Cardiopulmonary Bypass Time | Re-Thoracotomy | ICU Stay | Mechanical Ventilation Time

China
The Hospital for Sick Children
University of Calgary

Completed

Medi-Port Pilot Randomized Controlled Trial

Actively Undergoing Cancer Treatment | 4-9 Years of Age | At Least 1 Month From Diagnosis | Able to Speak and Understand English | Presenting to Clinic for at Least a 2nd Subcutaneous Port Needle Insertion

Canada
Apurano Pharmaceuticals GmbH

Recruiting

Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy

Pain | Chronic Pain | Neuropathic Pain | Peripheral Neuropathy | Pain, Chronic | Post Operative Pain | Chronic Pain Syndrome | Pain Syndrome | Peripheral Nerve Injury | Post-Traumatic Neuralgia | Peripheral Neuralgia | Plexopathy

Germany
Apurano Pharmaceuticals GmbH

Recruiting

Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy

Pain | Chronic Pain | Neuropathic Pain | Peripheral Neuropathy | Pain, Chronic | Post Operative Pain | Chronic Pain Syndrome | Pain Syndrome | Peripheral Nerve Injury | Post-Traumatic Neuralgia | Peripheral Neuralgia | Plexopathy

Germany
Shanghai Pulmonary Hospital, Shanghai, China

Completed

Comparison of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal VATS for Lung Cancer

Lung Diseases | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Carcinoma, Bronchogenic | Thoracic Surgery | Thoracic Neoplasm

China
University of Southern California
Bristol-Myers Squibb; National Cancer Institute (NCI); Astex Pharmaceuticals,...

Withdrawn

Guadecitabine and Nivolumab in Treating Refractory Metastatic Colorectal Cancer

Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Refractory Colorectal Carcinoma | CpG Island Methylator Phenotype | Metastatic Microsatellite Stable Colorectal Carcinoma

United States
AstraZeneca

Withdrawn

Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, PhaseⅡ, Double-Blinded, Placebo-Controlled Study (PROTECT)

Neurofibromatosis Type 1 | Plexiform Neurofibromas | Post-operative

China
Nan Shen
Novartis

Not yet recruiting

Disease and Biomarker Profiling of Chinese Lupus Nephritis

Characterize the Molecular Profile of Lupus Nephritis(LN) Patients to Understand Themechanism(s)Contributing to Patient Responsiveness to Soc | Integrated Analysis of LN Patient Molecular Profiling and Clinical Annotations to Understand LNdisease Heterogeneity for Disease Endotype | Validate the Association of the Candidate Biomarker Panel Proposed in Table 3-1 With LN Diseasemonitoring
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colon Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma

United States
Catholic University of the Sacred Heart
Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Recruiting

Post-Revascularization Optimization and PHysiological Evaluation of intermediaTe Lesions (PROPHET-FFR)

Coronary Disease | ST Elevation Myocardial Infarction | Angina, Stable | Ischemic Heart Disease | Unstable Angina | Non ST Elevation Myocardial Infarction

Italy
Fudan University

Not yet recruiting

A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal Metastasis (Miracle-1)

Advanced Rectal Cancer | Liver Metastasis | Pulmonary Metastasis | Microsatellite Stable Colorectal Carcinoma

China
NHS Greater Glasgow and Clyde
Abbott Medical Devices; University of Glasgow

Recruiting

iCorMicA - Stratified Medicine in Angina (iCorMicA)

Coronary Artery Disease | Angina, Stable | Microvascular Angina | Vasospastic Angina | Coronary; Ischemic | Non-Obstructive Coronary Atherosclerosis | Ischemia With No Obstructive Coronary Arteries (INOCA) | Coronary Microvascular Dysfunction (CMD) | Ischaemic Heart Disease | Angina Attacks

United Kingdom
An-Najah National University

Completed

Compressive Elastic Dressing Versus TR Band (Band Vs Gauze)

Myocardial Infarction | Coronary Artery Disease | Chest Pain | Angina, Stable | Acute Coronary Syndrome | Ischemic Heart Disease | Angina, Unstable | Atherosclerotic Cardiovascular Disease | Non ST Elevation Myocardial Infarction | STEMI | NSTEMI

Palestinian Territory, occupied
Assistance Publique - Hôpitaux de Paris
Imagine Institute; Axonal-Biostatem; CERBA laboratory; SATT; SNC Graft Versus Host...

Recruiting

Evaluation of a Donor Testing Kit for the Prediction of AGVHD in Patient Receiving a Peripheral Blood Stem Cell Allograft (Predictor2)

Acute Lymphoblastic Leukemia | Acute Myeloid Leukemia in Remission | Lymphoma in Remission | Non-progressive Myeloproliferative Syndrome | Myelodysplasia With Stable Blasts is Cell Number and < 10% of Blastocysts | Acute Leukemia Biphenotypic in Remission

France, Germany, Belgium
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety Study of Navarixin (MK-7123) in Combination With Pembrolizumab (MK-3475) in Adults With Selected Advanced/Metastatic Solid Tumors (MK-7123-034)

Non-small Cell Lung Cancer | Solid Tumors | Castration Resistant Prostate Cancer | Microsatellite Stable Colorectal Cancer

Canada, United States, Australia, Israel, Korea, Republic of
Assistance Publique - Hôpitaux de Paris

Withdrawn

Impact of Systematic Imaging for Follow up of Patients With Ovarian, Fallopian Tube or Primary Peritoneum Cancer (QUALOV)

Advanced Stage Serous Epithelial Cancer of the Ovary | Advanced Stage Cancer of Tubes | Advanced Stage Cancer of Peritoneum

France
Liaoning Tumor Hospital & Institute

Not yet recruiting

Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases

For Patients With Colorectal Cancer Liver Metastases Who Were Not Able to Curative Surgical Resection.Focused on the Treatment Effect With the Quintuple Method

China
Azienda Socio Sanitaria Territoriale degli Spedali...

Recruiting

Adherence and Compliance to ERAS in Gynecological Surgery (ERASGYNBS002)

Gynecologic Cancer | Ovarian Cancer | Cervix Cancer | Endometrial Cancer | Post Operative Pain | Uterine Cancer | ERAS | Gynecologic Neoplasm

Italy
Zimmer Biomet

Terminated

Post-market Surveillance Study With the HYPERION Hip Endoprosthesis System in Defect Reconstruction

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Femur Fracture | Trochanteric Fractures | Pseudarthrosis | Pseudoarthrosis | Functional Deformities | Revision of Endoprosthesis-treated Hips | Fracture, Proximal Humeral | Provision of Non-endoprosthetic Previous Operations of the Hip Joint (e.g... and other conditions

Germany
University of Utah

Completed

Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit

Post-operative Craniotomy Patients | Carotid Endarterectomy and Carotid Artery Stenosis Patients | Post-op Spine Patients Admitted to the NCCU | Endovascular Patients Undergoing Intracranial Intervention | Traumatic Brain Injuries NPO for at Least 12 Hours

United States
Indonesia University
Vygon GmbH & Co. KG

Completed

Efficacy of Sternum Guard in Post Cardiac Surgery Patient

Coronary Artery Disease | Surgical Site Infection | Postoperative Hemorrhage | Valvular Heart Disease | Congenital Heart Disease in Adolescence | Post Operative Wound Infection

Indonesia
Adlai Nortye Biopharma Co., Ltd.
Merck Sharp & Dohme LLC

Active, not recruiting

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Cervical Cancer | Triple-negative Breast Cancer | NSCLC, Squamous or Non-Squamous | Urothelial Carcinoma of the Bladder | Microsatellite Stable (MSS) Colorectal Cancer (CRC)

United States, France
An-Najah National University

Completed

Distal vs. Forearm Radial Artery Access (DRAvsFRA)

Myocardial Infarction | Myocardial Ischemia | Coronary Artery Disease | Chest Pain | Angina, Stable | Acute Coronary Syndrome | Angina, Unstable | Non ST Segment Elevation Myocardial Infarction | ST-segment Elevation Myocardial Infarction (STEMI) | Non STEMI | Atheroscleroses, Coronary | Atherosclerotic Heart...

Palestinian Territory, occupied
VA Office of Research and Development

Recruiting

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment (CSA)

Sleep Disordered Breathing | Able Bodied

United States
University College, London

Unknown

The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study

Heart Failure | Mortality | Peripheral Arterial Disease | Cardiac Arrest | Ventricular Arrhythmias | Acute Myocardial Infarction | Unstable Angina | Sudden Cardiac Death | Abdominal Aortic Aneurysm | Chronic Stable Angina | Coronary Heart Disease (CHD) | Non-ST Elevation Myocardial Infarction (nSTEMI) | ST Elevation... and other conditions

United Kingdom
Walter Reed National Military Medical Center

Recruiting

Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

Anger | PTSD | Sleep Disturbance | Posttraumatic Stress Disorder | Combat Stress Disorders | Nightmare | Post-Traumatic Headache | Military Activity | Posttraumatic Stress Disorder, Delayed Onset | Irritable Mood | Combat and Operational Stress Reaction | Military Family | Military Operations

United States
University of Aarhus

Completed

Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment (CONTEST)

Laparoscopic Surgery | Postoperative Complications | Intestinal Neoplasms | Bleeding | Venous Thromboembolism | Peritoneal Carcinomatosis | Cytoreductive Surgery | Peritoneal Metastases | Laparoscopy | Surgical Procedures, Operative | Coagulation | Colorectal Neoplasms Malignant | Minimally Invasive Surgical Procedures and other conditions

Denmark
Bezmialem Vakif University

Completed

Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia

Hematuria | Retention, Urinary | Operative Bleeding | Blood Transfusion Complication

Turkey
Zhong Wang

Recruiting

Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome)

Endometriosis | Headache | Chronic Insomnia | Chinese Medicine | Stable Coronary Heart Disease

China
NeoImmuneTech
Merck Sharp & Dohme LLC

Active, not recruiting

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (KEYNOTE A60)

Small Cell Lung Cancer | Pancreatic Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Microsatellite Stable Colorectal Cancer | Any Advanced Solid Tumors

United States
I.M. Sechenov First Moscow State Medical University

Recruiting

Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease

Coronary Artery Disease | Angina, Stable | Acute Kidney Injury | Angina, Unstable | Contrast-induced Nephropathy | NSTEMI - Non-ST Segment Elevation MI | STEMI - ST Elevation Myocardial Infarction

Russian Federation
University of Waterloo
YMCA; Royal Bank of Canada

Completed

Determining the Feasibility of Implementing a Combined Cognitive and Exercise Training Program for Older Adults in a Community Setting.

Obesity | Diabetes | Chronic Obstructive Pulmonary Disease | Fibromyalgia | Osteoporosis | High Blood Pressure | Osteo Arthritis | Joint Replacement | Stable Heart Conditions

Canada
University Hospital, Clermont-Ferrand
Groupama foundation; Biochemistry Lab University Hospital Clermont-Ferrand

Recruiting

Predictive Properties of Myocardial Fibrosis Biomarkers on the Outcome of Atrial Fibrillation Ablation (PROFIB-AF)

Women and Men Over 18 Years Old | AF Ablation (ECS recommendation2020&ACS2014) Either for Paroxysmal AF Unresponsive to Anti-arrhythmic Treatment Either for Persisting Symptomatic AF | Able to Give His Non Opposition to Participate to the Study

France
Roswell Park Cancer Institute
Merck Sharp & Dohme LLC

Withdrawn

Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Microsatellite Stable | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA... and other conditions

United States
University Health Network, Toronto

Completed

Study of Azacitidine and Durvalumab in Advanced Solid Tumors (METADUR)

Microsatellite Stable Colorectal Carcinoma | Platinum Resistant Epithelial Ovarian Cancer Type II | Estrogen Receptor Positive and HER2 Negative Breast Cancer

Canada
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Paclitaxel in Treating Patients With Ovarian Stromal Cancer

Adult Type Ovarian Granulosa Cell Tumor | Ovarian Gynandroblastoma | Ovarian Sertoli-Leydig Cell Tumor | Ovarian Sex Cord Tumor With Annular Tubules | Ovarian Steroid Cell Tumor

United States, Japan
Novartis
Novartis Vaccines

Completed

A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults

Japanese Encephalitis | Rabies | Yellow Fever | Meningococcal Disease | Typhoid | Meningococcal Meningitis

Czech Republic, Germany
A.O. Ospedale Papa Giovanni XXIII
University of Pisa; World Society of Emergency Surgery

Recruiting

Web-based International Register of Emergency Surgery and Trauma (WIRES-T)

Trauma | Abdominal Wall Hernia | Acute Pancreatitis | Intestinal Ischemia | Acute Cholecystitis | Acute Appendicitis | Acute Diverticulitis | Foreign Bodies | Post-operative Complications | Perforated Gastro-duodenal Ulcers | Adhesive Small Bowell Occlusion | Colonic Neoplastic Emergencies | Gynecological Emergencies and other conditions

Italy
Baskent University Ankara Hospital

Unknown

İntraoperative Awareness Under General Anesthesia

To Investigate the Incidence and Causes of Awareness During General Anesthesia | To Investigate the of Dreaming During Anesthesia | To Investigate the Intra-operative Experiences of Patients Who Report Awareness | To Investigate the Risk Factors That May be Associated With Awareness | To... and other conditions

Turkey
Memorial Sloan Kettering Cancer Center
Mayo Clinic; University of Chicago; University of Pittsburgh; Baptist Health South... and other collaborators

Active, not recruiting

Outcomes After Secondary Cytoreductive Surgery With or Without Carboplatin Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Followed by Systemic Combination Chemotherapy for Recurrent Platinum-Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Cancer | Peritoneal Cancer | Fallopian Tubes Cancer

United States
Compugen Ltd

Recruiting

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Multiple Myeloma | Ovarian Cancer | Lung Cancer | Advanced Cancer | Colon Cancer | Plasma Cell Neoplasm | HNSCC | Microsatellite Stable Colorectal Carcinoma | MSS-CRC

United States
Brown University

Recruiting

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Arthritis | Chronic Pain | Chronic Low-back Pain | Irritable Bowel Syndrome | Fibromyalgia | Acute Pain | Trauma, Multiple | Neuropathic Pain | Temporomandibular Joint Disorders | Post Operative Pain | Chronic Pain Syndrome | Chronic Shoulder Pain | Painful Diabetic Neuropathy | Chronic Migraine | Painful Bladder Syndrome and other conditions

United States
Novartis Pharmaceuticals

Terminated

A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies.

Ovarian Cancer | Non-small Cell Lung Cancer (NSCLC) | Renal Cell Carcinoma (RCC) | Triple Negative Breast Cancer (TNBC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Metastatic Castration Resistant Prostate Cancer (mCRPC) | Colorectal Cancer Microsatellite Stable (MSS)

Canada, Australia, Singapore, United States, Japan, Spain, United Kingdom
GOG Foundation
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors

Ovarian Gynandroblastoma | Ovarian Sertoli-Leydig Cell Tumor | Ovarian Sex Cord Tumor With Annular Tubules | Ovarian Steroid Cell Tumor | Ovarian Granulosa Cell Tumor | Ovarian Sex Cord-Stromal Tumor | Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified

United States
Inion Oy

Recruiting

Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation

Fractures, Bone | Foot Deformities | Ankle Fractures | Hallux Valgus | Hallux Rigidus | Fracture of Foot | Lisfranc Fracture | Metatarsalgia | Lisfranc Injury | Deformity, Foot | Calcaneus Fracture | Talus Fracture | Medial Malleolus Fracture | Navicular Fracture | Foot Fracture | Foot Injury | Feet Deformity Tarsus | Deformity... and other conditions

Finland
State University of New York - Upstate Medical...

Terminated

Genetic Disease Gene Identification

Familial Encephalopathy With Neuroserpin Inclusion Bodies | X-linked Mental Retardation | Congenital Vertical Talus | Idiopathic Generalised Epilepsy | Familial Dementia

United States

Clinical Trials on Operating Tables [E07.325.662]

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