Clinical Trials on Overdose Antidote

Total 239 results

University of Washington
U.S. National Science Foundation

Completed

Naloxone Auto-injection in Healthy Volunteers

Overdose Antidote

United States
Canadian Forces Health Services Centre Ottawa

Recruiting

Assessment of Injectable Medication Platforms

Bleeding | Allergic Reaction | Overdose Antidote

Canada
San Francisco Department of Public Health

Recruiting

Leveraging Psychological Autopsies to Accelerate Research Into Stimulant Overdose Mortality (LASSO)

Stimulant Overdose | Overdose Accidental | Overdose Cocaine | Overdose Methamphetamine

United States
Isfahan University of Medical Sciences

Completed

Randomized Trial of Intranasal Versus Intravenous Naloxone in Level of Consciousness in Suspected Opioid Overdose

Morphinan Opioid Overdose

Iran, Islamic Republic of
Brown University

Completed

Rapid Self-Testing to Prevent Fentanyl Overdose Among Young People Who Use Drugs (RAPiDS2)

Accidental Overdose of Opiate

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA); Indivior Inc.

Completed

Risks and Benefits of Naloxone Prescribing

Opioid Overdose

United States
University of Washington
National Institute on Drug Abuse (NIDA)

Completed

Project OOPEN: Opioid Overdose Prevention, Education and Intervention (OOPEN)

Opioid Overdose

United States
RTI International
National Institute on Drug Abuse (NIDA)

Unknown

Preventing Opioid Overdose Mortality in the United States

Opioid Overdose

United States
Centro Hospitalar do Porto

Completed

Propofol Pharmacokinetics and Pharmacodynamics Modelling

Intravenous Anesthetic Agent Overdose

Portugal
Medical University of South Carolina
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC; National Drug...

Completed

Peer Intervention to Link Overdose Survivors to Treatment (PILOT) (PILOT)

Opioid Overdose

United States
New York State Psychiatric Institute

Suspended

Tailoring Overdose Education for Black Churches

Opioid Overdose

United States
Nassima Ait-Daoud Tiouririne

Unknown

Measures to Improve Outcomes After an Opioid Overdose

Opioid Overdose

United States
Mitovie Pharma Ltd

Unknown

Naloxone Nasal Spray Pharmacokinetic Study

Opioid Overdose

Jordan
West China Hospital

Completed

Application of the Propofol Precise Infusion Model

Propofol Overdose of Undetermined Intent

China
King's College London
Mundipharma Research Limited

Recruiting

European Cohort Study of the Effectiveness of Take Home Naloxone (NalPORS)

Opioid Overdose

Denmark, United Kingdom, Sweden
Auburn University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Preventing Opioid Overdose Deaths by Empowering Pharmacists to Dispense Naloxone

Opioid Overdose

United States
Ankara University

Completed

Local Anesthesia Impact on Dental Sedation

Sedative Overdose

Turkey
University of Pennsylvania

Active, not recruiting

Stimulant Overdose in the Medicaid Population: Who is at Risk, and When Are They at Risk

Stimulant Overdose

United States
Parc de Salut Mar

Completed

Synchronous Effect of Anesthetics on fMRI, EEG and Clinical Responses

Sedative Overdose

Spain
ART Fertility Clinics LLC

Terminated

Measurement of Midazolam Levels in Follicular Fluid

Midazolam Overdose

United Arab Emirates
Egetis Therapeutics
University of Edinburgh; NHS Lothian

Completed

PP100-01 (Calmangafodipir) for Overdose of Paracetamol (POP)

Paracetamol Overdose

United Kingdom
Cumberland Pharmaceuticals

Terminated

Safety and Efficacy Study of a New Formulation of Acetylcysteine Injection

Acetaminophen Overdose

United States
Hartford Hospital
Hartford HealthCare

Not yet recruiting

Improving Availability of Intranasal Naloxone

Opioid Overdose

United States
NYU Langone Health
Centers for Disease Control and Prevention

Completed

Multi-Center Randomized Controlled Trial of Relay- NYC's Nonfatal Overdose Response Program

Opioid Overdose

United States
Emergent BioSolutions

Completed

Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy Adults

Opioid Overdose

United States
University Hospital Bispebjerg and Frederiksberg

Completed

Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition (GLUCAGON)

Drug Overdose | Overdose of Beta-adrenergic Blocking Drug

Denmark
Urs E. Nydegger
Labormedizinisches Zentrum Dr. Risch

Unknown

Impact of Oral Glucose Tolerance Test on Extent of Hemoglobin Glycation (HbA1c)

Blood Glucose, High | Oral Hypoglycaemic Overdose

Switzerland
Azienda Ospedaliera "Sant'Andrea"

Unknown

Picoprep Split-dose Before Colonoscopy in Children

Bowel Disease | Children, Only | Sodium Picosulfate Overdose | Magnesium Sulfate Overdose
University of Chile

Completed

Dose-response Curves Between Propofol and Intraoperative Electroencephalographic Patterns

Propofol Overdose | EEG

Chile
National Taiwan University Hospital

Unknown

To Establish a Novel Prototype of Clinical Pharmacy Services by Warfarin Consultation in a Pharmacist Clinic

Intentional Warfarin Sodium Overdose

Taiwan
Wanqi Zhang
Shandong Institute for Endemic Disease Control and Research; Tianjin Maternal...

Unknown

The Effect of Iodine Intakes on Maternal and Infant Health and the Study of Iodine RNI for Different Stages of Pregnancy

Pregnancy Related | Iodine Reaction | Iodine Compounds Overdose

China
Northwestern University
Emory University; McNeil Consumer & Specialty Pharmaceuticals, a Division of...

Completed

Investigation of Efficacy of Improved Acetaminophen Labeling

Pain | Acetaminophen Overdose

United States
University Hospital, Strasbourg, France

Terminated

Acute Acetaminophen Ingestion: Does Repeated Acetaminophen Blood Test Have an Interest?

Acetaminophen Overdose

France
Universidad del Desarrollo
Pontificia Universidad Catolica de Chile

Completed

Performance Evaluation of Four Pharmacokinetic-Pharmacodynamic(PKPD) Models of Propofol in Elderly Patients (TCIGeriatric)

Propofol Overdose of Undetermined Intent

Chile
West China Hospital

Completed

A Dose-response Study of Lidocaine and Etomidate

Etomidate Overdose of Undetermined Intent
Adiyaman University Research Hospital

Unknown

The Effect of Heparinization Due to LBW (LBWH)

Bleeding | Heparin | Heparin Overdose
Mikkel Bring Christensen

Completed

Effects of Lipid Emulsion on the Pharmacokinetic and Pharmacodynamic Properties of Metoprolol.

Blood Pressure | Drug Overdose | Overdose of Beta-adrenergic Blocking Drug

Denmark
Lihong Chen

Completed

Clinical Observation of Titration Induction and Convention Induction of Propofol

Propofol Overdose of Undetermined Intent

China
San Francisco Department of Public Health

Completed

Repeated-dose Behavioral Intervention to Reduce Opioid Overdose (REBOOT)

Opioid-Related Disorders | Drug Overdose

United States
Johns Hopkins Bloomberg School of Public Health
Centers for Disease Control and Prevention

Completed

An Evaluation of a Social Network Intervention for Primary and Secondary Prevention of Opioid Overdoses

Overdose

United States
Member Companies of the Opioid PMR Consortium
Vanderbilt University; Kaiser Permanente; HealthCore, Inc.; Optum, Inc.; World Health...

Completed

Incidence and Predictors of Opioid Overdose and Death Among Long-Term Users of Opioid Analgesics

Opioid Overdose

United States
Edward Hospital

Completed

Increasing Patient Knowledge of the Signs of Opioid Overdose and Naloxone in a Suburban Treatment Program

Opioid Use Disorder | Opioid Dependence

United States
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses (TTIP-PRO)

Opioid-Related Disorders | Substance Abuse | Drug Overdose | Drug Abuse | Drug Addiction

United States
BC Centre on Substance Use
Indivior Inc.

Recruiting

Extended-release Injectable Buprenorphine for Individuals at High Risk of Overdose (FASTER-BUP)

Opioid Overdose | Opioid-Use Disorder

Canada
Nationwide Children's Hospital

Recruiting

Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit Stimulants

Harm Reduction | Opiate Overdose | Fentanyl Overdose

United States
Nationwide Children's Hospital

Recruiting

Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties

Harm Reduction | Opiate Overdose | Fentanyl Overdose

United States
RTI International
University of California, San Diego; Heluna Health

Recruiting

Improving Equitable Access to Naloxone to Prevent Opioid Overdose Deaths Within Syringe Service Programs (SAIA-Naloxone) (SAIA-N)

Overdose | Implementation as Usual

United States
Pontificia Universidad Catolica de Chile

Unknown

PK/PD Levobupivacaine With and Without Epinephrine After Ultrasound Guided ESP Block

Surgery | Nerve Block | Anesthetic Toxicity | Anesthetics Complications | Bupivacaine Overdose

Chile
Unity Health Toronto
University of Toronto; Toronto Public Health; Ontario College of Art and Design...

Withdrawn

Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER) (SOONER)

Opioid-Related Disorders | Opioid Use | Education | Opioid Withdrawal | Opioid Overdose | Resusitation

Canada
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Evaluation of a Computerized Opioid Overdose Prevention Program

Treatment as Usual | Computer + Fluency | Computer Only

United States

Clinical Trials on Overdose Antidote

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