Clinical Trials on Painful Polyneuropathy

Total 454 results

Odense University Hospital

Completed

Levetiracetam for Painful Polyneuropathy

Painful Polyneuropathy

Denmark
Analgesic Solutions
Pfizer; Astellas Pharma Europe B.V.

Unknown

Evaluation of the Impact of Training on Outcome Measures in Subjects With Painful Diabetic Neuropathy

Diabetes Mellitus | Painful Distal Symmetric Sensorimotor Polyneuropathy

United States
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Terminated

A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)

Diabetic Neuropathy, Painful | Diabetic Polyneuropathy

United States
East Bay Institute for Research and Education

Completed

Treatment of Painful Diabetic Neuropathy With Photon Stimulation

Diabetic Neuropathy, Painful | Diabetic Polyneuropathy | Diabetic Neuralgia | Diabetic Mononeuropathy

United States
University of Aarhus

Recruiting

Peripheral Nerve Block in Patients With Painful Diabetic Polyneuropathy

Neuropathic Pain | Painful Diabetic Neuropathy | Neuropathy;Peripheral

Denmark
Astellas Pharma Europe Ltd.

Completed

A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment (ELEVATE)

Non-diabetic Painful Peripheral Polyneuropathy | Postherpetic Neuralgia (PHN) | Peripheral Nerve Injury (PNI)

Armenia, Austria, Belarus, Belgium, Bulgaria, Czechia, Finland, France, Germany, Greece, Hungary, Italy, Poland, Portugal, Romania, Russian Federation, Slovakia, Slovenia, Spain, Sweden, Turkey, United Kingdom
Tanta University

Completed

Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study

Diabetic Neuropathies | Diabetic Peripheral Neuropathy | Painful Diabetic Neuropathy | Autonomic Neuropathy | Diabetic Polyneuropathy | Small Fiber Neuropathy

Egypt
AbbVie (prior sponsor, Abbott)

Completed

Safety and Efficacy Study in Subjects With Diabetic Neuropathic Pain

Diabetic Neuropathies | Diabetic Neuropathy, Painful | Diabetic Polyneuropathy | Diabetic Neuralgia | Neuralgia, Diabetic

United States, Canada, France, Germany, Italy, Mexico, Puerto Rico
SK Life Science, Inc.

Completed

Study for Safety and Effectiveness of RWJ-333369 (Carsibamate) for the Treatment of Diabetic Peripheral Neuropathy (DPN).

Diabetic Neuropathy, Painful | Diabetic Polyneuropathy | Diabetic Neuralgia | Diabetic Mononeuropathy
Merck Sharp & Dohme LLC

Completed

Neuropathic Pain Syndrome Patient Study (MK-0000-072)

Diabetic Neuropathy | Neuralgia, Postherpetic | Painful Small-Fiber Neuropathy | Idiopathic Distal Sensory Polyneuropathy
University of Pennsylvania
National Institutes of Health (NIH)

Active, not recruiting

FDG-PET Imaging in Painful Joint Prosthesis

Painful Joint Prostheses

United States
University Hospital, Bordeaux

Recruiting

Painful Breastfeeding and Osteopathic Treatment on the Mother-newborn Dyad (AMATOSTEO)

Painful Breastfeeding

France
Pfizer

Completed

The Effect Of Tafamidis Meglumine In Transthyretin Amyloid Polyneuropathy Patients

Transthyretin Amyloid Polyneuropathy (ATTR-PN)

China
Massachusetts General Hospital

Terminated

Study of Sulfasalazine in Treating Painful Neuropathy

Painful Neuropathy

United States
Aaron Boster

Withdrawn

Single Shot Intrathecal Ziconotide for Painful Neuropathy or Myelopathy

Painful Neuropathy | Painful Myelopathy

United States
German Cancer Research Center
University Hospital Heidelberg; National Center for Tumor Diseases, Heidelberg

Completed

Prevention of Chemotherapy-Related Polyneuropathy Via Sensorimotor Exercise Training (PIC)

Exercise | Chemotherapy-induced Polyneuropathy

Germany
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Improving Mobility in Diabetic Patients Through Resistance Training

Diabetic Patients With Polyneuropathy

Netherlands
Nycomed

Completed

Actovegin® Versus Placebo in Patients With Diabetic Polyneuropathy (AV-007-IM)

Symptomatic Diabetic Peripheral Polyneuropathy

Denmark
Pfizer

Completed

The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M Transthyretin

Transthyretin Familial Amyloid Polyneuropathy

Japan
Peking University Third Hospital

Recruiting

The Effect of Tafamidis on Transthyretin Stabilization, Safety, Tolerability and Efficacy in Transthyretin Amyloid Polyneuropathy Patients

Transthyretin Amyloidosis

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study To Evaluate the Safety, Tolerance, Pharmacokinetics/Pharmacodynamics and Efficacy of SYHA1402 Tablets For the Treatment of Patients With Diabetic Peripheral Neuropathy in China

Distal Symmetric Polyneuropathy (DSPN)
University Health Network, Toronto

Completed

Can Ultrasound Detect Diabetic Peripheral Neuropathy?

Distal Symmetric Polyneuropathy (DSPN)

Canada
Eisai Inc.

Completed

Evaluating the Efficacy and Safety of Oral Ranirestat (40 and 80 mg) in Mild to Moderate Diabetic Sensorimotor Polyneuropathy

Mild to Moderate Diabetic Sensorimotor Polyneuropathy

United States
Vanderbilt University
UCB Pharma

Completed

A Study to Determine if Levetiracetam Will Assist Those Suffering From Chronic Idiopathic Axonal Polyneuropathy.

Chronic Idiopathic Axonal Polyneuropathy

United States
Eva Pharma
MARC-CRO

Recruiting

Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)

Polyneuropathy, Diabetic

Egypt
Ionis Pharmaceuticals, Inc.

Recruiting

A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

United States, Italy, Portugal, Spain, Taiwan, Sweden, Canada, Brazil, France, New Zealand, Argentina, Cyprus, Australia, Turkey
Ionis Pharmaceuticals, Inc.

Completed

NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

United States, Spain, Taiwan, Italy, Germany, Argentina, Australia, Brazil, Canada, Cyprus, France, Greece, New Zealand, Portugal, Sweden, Turkey
University of Kansas Medical Center
Patient-Centered Outcomes Research Institute

Completed

Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS)

Cryptogenic Sensory Polyneuropathy

United States, Canada
Vertex Pharmaceuticals Incorporated

Recruiting

Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR)

Painful Lumbosacral Radiculopathy

United States
WinSanTor, Inc

Completed

A 24-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Peripheral Neuropathy

Peripheral Neuropathy | Painful Diabetic Neuropathy | Diabetic Neuropathies, Painful

Canada
Biogen

Completed

Phase 1 Subcutaneous Single and Multiple Ascending Dose Study of BG00010 (Neublastin)

Healthy | Painful Lumbar Radiculopathy

Netherlands
University Of Perugia

Unknown

Botulinum A Toxin in the Treatment of Patients With Painful Bladder Syndrome

Painful Bladder Syndrome (PBS)

Italy
Centre Hospitalier Universitaire de Saint Etienne
Laboratoire français de Fractionnement et de Biotechnologies

Completed

Randomized Open-label Trial to Compare Efficacy and Tolerance of Corticosteroids and IVIg (PRNC)

Demyelinating Polyneuropathy

France
Assiut University

Unknown

Psychiatric Comorbidities in Patients With Painful Peripheral Neuropathy

Painful Peripheral Neuropathy
David J. Kopsky
Princess Beatrix Muscle Foundation; Dr. C.J. Vaillant Fonds

Completed

Phenytoin Cream for the Treatment of Neuropathic Pain (EPHENE)

Chronic Idiopathic Axonal Polyneuropathy

Netherlands
University Hospital, Bordeaux

Recruiting

Comparison of FEETME® Soles and GAITRITE® Walkway for the Evaluation of Gait Disorders in CIDP. (ESCAL-PIDC)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

France
Fondazione I.R.C.C.S. Istituto Neurologico Carlo...
Yale University; University of Manchester; Maastricht University; Ospedale San... and other collaborators

Unknown

Probing the Role of Sodium Channels in Painful Neuropathies

Painful Peripheral Neuropathy | Painless Peripheral Neuropathy
University of Aarhus
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; Aalborg University Hospital

Recruiting

Subcutaneous Immunoglobulin in De-novo CIDP (SIDEC) (SIDEC)

CIDP - Chronic Inflammatory Demyelinating Polyneuropathy

Denmark
Vera Bril

Unknown

Panzyga in CIDP Administered at Different Infusion Rates (Panzyga-CIDP)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Canada
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of Acoramidis (AG10) in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
CSL Behring

Completed

Extension Study of Maintenance Treatment With Subcutaneous Immunoglobulin (IgPro20) for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

United States, Japan, Australia, Canada, Czechia, France, Germany, Italy, Netherlands, Spain, United Kingdom
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy

United States
SOM Innovation Biotech SA
Hospital Vall d'Hebron

Completed

Study of SOM0226 in Familial Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy (FAP)

Spain
Institut Mutualiste Montsouris
Assistance Publique - Hôpitaux de Paris; Fondation Paul Bennetot

Unknown

Neuromuscular Electrical Stimulation for Intensive Care Unit-acquired Weakness Assessment (ENS)

Polyneuropathy, Critical Illness

France
Ilko Ilac San. ve Tic. A.S.

Completed

To Assess the Bioequivalence of Test Oral Formulation of Alpha Lipoic Acid 600 mg HR Film Coated Tablets of Ilko Ilac San. Ve Tic. A.S. Versus Reference Thioctacid (Alpha Lipoic Acid) 600 mg HR Film Coated Tablets of Meda Pharma GmbH& CO .KG, Germany.

Peripheral (Sensorimotor) Diabetic Polyneuropathy
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy

Moderate to Severe Pain Due to Diabetic Polyneuropathy

Germany
Henry Ford Health System
Octapharma USA, Inc.

Recruiting

IVIG in the Treatment of Autoimmune Small Fiber Neuropathy With TS-HDS, FGFR-3, or Plexin D1 Antibodies

Small Fiber Neuropathy | Autoimmune Small Fiber Neuropathy | Inflammatory Polyneuropathy | Immune-Mediated Neuropathy

United States
Case Western Reserve University

Not yet recruiting

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

Interstitial Cystitis | Painful Bladder Syndrome (PBS)
WALA Heilmittel GmbH

Recruiting

Clinical Trial With Aconite Pain Oil in Oncology Patients Under Chemotherapy to Prevent CIPN Grade-II, to Reduce Symptoms and to Improve the Quality of Life of Patients With CIPN

Chemotherapy-induced Polyneuropathy

Germany
The Second Hospital of Tangshan
Chinese PLA General Hospital; The Second Hospital of Qinhuangdao

Completed

Treatment of Painful Digital Neuroma Using A Pedicled Nerve Flap

Painful Digital Neuroma

China

Clinical Trials on Painful Polyneuropathy

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CROs in Philippines

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Drug Interventions

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