Clinical Trials on Perinatal Depression, Substance Use

Total 3421 results

University of Rochester

Not yet recruiting

The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

Age-Related Macular Degeneration | Retinitis Pigmentosa | Retinal Dystrophies | Alcohol Use Disorder | Stargardt Disease

United States
Centre Hospitalier Henri Laborit

Not yet recruiting

Study of Prevalence of Eating Disorder in Liver Transplant Patients (Pré-THETA)

Alcohol Use Disorder | Liver Transplant; Complications | Eating Disorders | Cirrhosis Alcoholic | Eating Disorder Binge

France
Unity Health Toronto

Recruiting

Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial (EPOCH)

Chronic Pain | Anesthesia, Local | Opioid Use Disorder | Post-operative Pain | Post-cardiac Surgery | Post-operative Delirium

Canada
University of Nebraska
VA Nebraska Western Iowa Health Care System

Completed

Airway Macrophages and Sputum Milieu in Adult Subjects With Airflow Obstruction

Pulmonary Disease, Chronic Obstructive | Occupational Diseases | Tobacco Use Disorder | Bronchitis, Chronic

United States
University of Pennsylvania

Completed

Effectiveness of Patient-centered Community Health Worker Support to Help Patients Control Chronic Disease

Hypertension | Obesity | Diabetes | Asthma/COPD With Tobacco Dependence

United States
Medical University of South Carolina
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Treatment of Alcohol Dependence and Comorbid Bipolar Disorder

Depression | Alcohol Dependence | Bipolar Disorder | Mania | Psychosis

United States
Centre de Recherche de l'Institut Universitaire...

Unknown

Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers

Depressive Disorder | Anxiety Disorders | Stress Disorders, Post-Traumatic | Substance Abuse | Absenteeism | Acute Stress Disorder

Canada
Yale University
National Institute on Drug Abuse (NIDA); West Virginia University

Active, not recruiting

Buprenorphine Integration Research and Community Health (BIRCH)

HIV Infections | Hepatitis C | Opioid Use Disorder

United States
University of Pittsburgh

Withdrawn

Early Detection of Alcoholic Liver Disease

Alcohol Dependence | Alcohol-Related Disorders | Alcohol Use Disorder | Alcoholic Liver Disease | Alcohol Abuse | Alcoholic Fibrosis of Liver | Alcoholic Cirrhosis | Excessive Drinking
Finnish Institute for Health and Welfare
Hospital District of Helsinki and Uusimaa; Pirkanmaa Hospital District; Northern...

Recruiting

Youth Experiences and Health Study (YEAH)

Psychotic Disorders | Cannabis Use | Prodromal Symptoms | Trauma, Psychological | Psychiatric Hospitalization

Finland
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

COVID EHR COHORT at the University of Wisconsin (CEC-UW)

Cardiovascular Diseases | COVID-19 | Cancer | Pulmonary Disease | Nicotine Dependence | Immunosuppression Disorders

United States
VA Office of Research and Development

Completed

Cardiovascular Risk Screening and Risk Reduction in Women Vets

Cardiovascular Diseases | Hypertension | Obesity | Diabetes Mellitus | Overweight | Dyslipidemias | Tobacco Use Disorder | Hyperlipidemias

United States
University of Washington
Patient-Centered Outcomes Research Institute

Completed

A Comparative Effectiveness Trial of Optimal Patient-Centered Care (TSOS 5)

Post Traumatic Stress Disorder | Post Traumatic Concerns | Depression and Suicide Ideation | Alcohol and Drug Use

United States
Hospital for Special Surgery, New York

Completed

Aromatherapy in Total Knee Replacement

Depression | Anxiety | Opioid Use | Post Operative Pain | Total Knee Replacement | Post-operative Nausea and Vomiting

United States
Wayne State University
National Institute on Drug Abuse (NIDA)

Completed

Medical Marijuana Use in HIV+ Patients Prospective Cohort Study (MMC-1)

Marijuana Smoking | HIV Positive

United States
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Completed

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot (TSOS6)

Substance-Related Disorders | Depression | Alcohol-Related Disorders | Quality of Life | Suicidal Ideation | Mild Cognitive Impairment | Posttraumatic Stress Disorder
University of Oklahoma
Centers for Disease Control and Prevention

Completed

Development of Education Materials for Prevention of FAS in Russia

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome (FAS) | Alcohol Related Neurodevelopmental Disorder | Alcohol Use Complicating Pregnancy, Unspecified Trimester

United States, Russian Federation
Tetra Bio-Pharma

Suspended

Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexia Progression in Patients With Advanced Cancer and Associated Cachexia (SERENITY)

Advanced Cancer | Cannabis Use | Cachexia; Cancer

Canada
Neurocrine Biosciences

Recruiting

Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Tardive Dyskinesia | Major Depressive Disorder

United States
VA Office of Research and Development
University of Pennsylvania; Walter Reed National Military Medical Center; Brooke...

Completed

Regional Anesthesia Military Battlefield Pain Outcomes Study (RAMBPOS)

Anxiety Disorders | Substance Abuse | Post-Traumatic Stress Disorder | Depressive Disorders | Complex Regional Pain Syndrome Type II

United States
Helse Nord-Trøndelag HF

Completed

Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic

Liver Failure | HEART DISEASE | DEPRESSIVE DISORDER | Alcoholic Neuropathy

Norway
University of Texas at Austin
Way West Wellness; SunFlora.Inc

Suspended

CBD Oil for Reducing Emotional Impact of COVID-19 (CBDOIL)

Anger | Sleep Disturbance | Anxiety Depression | Substance Abuse | Alcohol Abuse | Stress Reaction

United States
University of Nottingham

Recruiting

Nottingham Community Liver Biomarkers Cohort

Obesity | Type 2 Diabetes | Alcohol Use Disorder | Chronic Liver Disease | Persistently Elevated ALT

United Kingdom
Wake Forest University Health Sciences

Completed

Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain

Back Pain | Chronic Pain | Neuropathic Pain | Opioid Use | Pain, Chronic | Opiate Dependence | Chemotherapy-induced Peripheral Neuropathy | Chronic Lower Back Pain

United States
University of Alabama at Birmingham
University of Bern; Centre for Infectious Disease Research in Zambia

Completed

Antiretroviral Treatment Outcomes in HIV-HBV Co-infected Patients in Southern Africa

HIV | Antiretroviral Therapy | Alcohol Use Disorder | Liver Fibrosis | Hepatitis B Virus | Africa

Zambia
University of Pennsylvania
National Cancer Institute (NCI); Northwestern University

Recruiting

Optimizing Tobacco Use Treatment for PLWHA (HTO)

HIV/AIDS | Nicotine Dependence

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients

Breast Cancer | Colorectal Cancer | Tobacco Use Disorder | Lung Cancer | Prostate Cancer

United States
Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Health and Wellness After Preterm Birth

Depression | Tobacco Use | Preterm Birth | Health Care Utilization | Contraceptive Usage | Weight, Birth

United States
Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth

Depression | Tobacco Use | Preterm Birth | Health Care Utilization | Contraceptive Usage | Weight, Birth

United States
Cairo University
Ain Shams University hospitals

Unknown

Effectiveness of N-acetyl Cysteine, Acetyl L- Carnitine and Medicated Paraffin Oil in Aluminium Phosphide Poisoning

the Study Focus to Improve the Standard of Care Used for Aluminuim Phosphide Poisoning and to Save Patients With the Minimal Organ Damage

Egypt
San Diego State University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of California... and other collaborators

Enrolling by invitation

Development of an Intervention to Reduce Heavy Drinking and Improve HIV Care Engagement Among Fisherfolk in Uganda

Alcohol Use Disorder | HIV-infection/Aids

Uganda
University of Washington
National Institute on Drug Abuse (NIDA)

Recruiting

Combination Primary Care and Prevention Services for Women Who Inject Drugs and Exchange Sex in Seattle, Washington

HIV Infections | Opioid Use Disorder | Chlamydia | Gonorrhea | Syphilis | Trichomonas

United States
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)

Chronic Pain | Opioid-Related Disorders | Opioid Use Disorder | Opioid Dependence | Chronic Pancreatitis | Hyperalgesia | Chronic Pain Syndrome | ERCP | Pancreatic Surgery | Chronic Abdominal Pain

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Memantine Hydrochloride in Helping Cancer Survivors Stop Smoking

Breast Cancer | Colorectal Cancer | Tobacco Use Disorder | Lung Cancer | Prostate Cancer

United States
Rhode Island Hospital

Recruiting

Combined Injectable Treatment for HIV and OUD (CHOICE)

Opioid Use Disorder | Human Immunodeficiency Virus

United States
University of Leicester

Recruiting

The Multi-Ethnic Lifestyle Study (MELS)

Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) | Cardiovascular Diseases | Stroke | Healthy | Diabetes Mellitus | Cancer | Chronic Kidney Diseases | Chronic Pain | Obstructive Sleep Apnea | Respiratory Disease

United Kingdom
National University of Singapore
Melbourne Health; Karolinska Institutet; National University Hospital, Singapore and other collaborators

Unknown

Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II) (SLAS)

Depression | Dementia | Frailty | Mild Cognitive Impairment | Healthy Ageing | Cognitive Changes Due to Organic Disorder (Finding) | Biological Ageing

Singapore
Brian Edlin
Weill Medical College of Cornell University; State University of New York -...

Unknown

Hepatitis C Treatment in Underserved Populations

Chronic Hepatitis C | Illicit Drug Use

United States
VA Office of Research and Development

Active, not recruiting

Pilot rTMS for AUD+mTBI (TMS_AUD+mTBI)

Alcohol Use Disorder | Post-traumatic Stress Disorder | Mild Traumatic Brain Injury

United States
VA Office of Research and Development

Completed

Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop (STEP-Home)

Depression | Pain | Anxiety Disorders | Suicide | Traumatic Brain Injury | Substance Related Disorders | Post-traumatic Stress Disorder

United States
Columbia University
National Institute of Mental Health (NIMH); Yale University

Active, not recruiting

Building Mobile HIV Prevention and Mental Health Support in Low-resource Settings

Depression, Anxiety | Human Immunodeficiency Virus | Risk Reduction | Alcohol Abuse | Behavior, Sex

Romania
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs (NeoAKI STOP) (NeoAKISTOP)

Premature Birth | Acute Kidney Injury | Drug Use | Machine Learning | Newborn Morbidity | Drug Interaction | Drug Toxicity | Drug-Induced Nephropathy

Italy
Grupo Espanol de Investigacion en Sarcomas

Active, not recruiting

Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST) (SeliGIST)

Drug Use | GIST | Drug Toxicity | Metastatic Adult Soft Tissue Sarcoma | Maximum Tolerated Dose

Spain
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Completed

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity (TSOS6)

Substance-Related Disorders | Depression | Alcohol-Related Disorders | Quality of Life | Pain | Brain Injuries | Chronic Disease | Suicidal Ideation | Mild Cognitive Impairment | Posttraumatic Stress Disorder | Wounds and Injury

United States
Klinički Bolnički Centar Zagreb

Unknown

Survey on Pre-ECT Evaluation and ECT Application

Depression | Schizophrenia | Schizoaffective Disorder | Catatonia | Suicidal Intention | Malignant Neuroleptic

Croatia
Wuhan University
Peking University; Pfizer

Unknown

Efficacy and Safety of Ziprasidone to Treat Depressive Symptoms in Patients With Schizophrenia

The Primary Evaluation is the Change From Baseline at End of Study for CDSS Total Scores. | The Secondary Efficacy Evaluations Include: MADRS, PANSS Total Scores and Subscales and Responder Rate; CGI-S and CGI-I Scales. | Safety Evaluations Include: Laboratory Test Abnormalities; BARS... and other conditions
VistaGen Therapeutics, Inc.

Not yet recruiting

AV-101 (L-4-chlorokynurenine) in Parkinson's Disease Subjects With Levodopa-Induced Dyskinesia

Parkinson Disease | Dyskinesia, Medication-Induced | L-Dopa Causing Adverse Effects in Therapeutic Use
Hospitalsenheden Vest
Boehringer Ingelheim; Erasmus Medical Center; University of Aarhus; Catharina Ziekenhuis... and other collaborators

Completed

Adherence and Coagulation Assays in Dabigatran-treated Patients With Atrial Fibrillation (ARCADE)

Thrombosis | Atrial Fibrillation | Bleeding | Medication Adherence | Drug Effect | Anticoagulants; Circulating, Hemorrhagic Disorder | Drug Use | Blood Coagulation Disorder | Laboratory Problem | Drug Toxicity | Blood Clot | Blood Coagulation Tests | Drug Intolerance

Denmark
University of Tennessee

Completed

Oliceridine in Patients With Acute Burn Injuries (RELIEVE)

Burns | Acute Pain | Adverse Drug Event | Respiratory Depression | Nausea and Vomiting, Postoperative

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Enhanced Quitline Intervention in Smoking Cessation for Patients With Non-Metastatic Lung Cancer

Tobacco Use Disorder | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Recurrent Small Cell Lung Cancer | Limited Stage Small Cell Lung Cancer | Stage IA Non-small Cell Lung Cancer | Stage IB Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB...

United States

Clinical Trials on Perinatal Depression, Substance Use

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