Clinical Trials on Pleural Diseases in United States

Total 147291 results

University of California, Irvine
Beckman Laser Institute University of California Irvine

Withdrawn

Optical Coherence Tomography of Airway and Pleural Disorders

Disorder of Pleura and Pleural Cavity

United States
Mayo Clinic

Recruiting

Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
Mayo Clinic

Recruiting

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
Mayo Clinic

Recruiting

Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions

Pleural Neoplasm

United States
Johns Hopkins University

Enrolling by invitation

Biomarker Levels During Indwelling Pleural cAtheter Sample Testing (BLAST)

Malignant Pleural Effusions

United States
Eastern Regional Medical Center

Recruiting

Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions

Loculated or Non-draining Malignant Pleural Effusions

United States
Oregon Health and Science University
The Gerber Foundation

Completed

Fortified Skimmed Mother's Milk in the Management of Chylothorax

Chylous Pleural Effusion Following Cardiothoracic Surgery

United States
Washington University School of Medicine
Merit Medical Systems, Inc.

Completed

Management of Malignant Pleural Effusions Using an Indwelling Tunneled Pleural Catheter and Non-Vacuum Collection System

Malignant Pleural Effusion

United States
Duke University

Terminated

Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion

Malignant Pleural Effusion

United States
The Cooper Health System

Unknown

Talc Outpatient Pleurodesis With Indwelling Catheter (TOPIC)

Pleural Diseases | Pleural Effusion | Malignant Pleural Effusion

United States
M.D. Anderson Cancer Center

Terminated

Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis

Advanced Cancers | Malignant Pleural Effusions

United States
University of Oklahoma

Completed

iSTAT Comparison Study, IRB3785

Pleural Effusions

United States
M.D. Anderson Cancer Center
United States Department of Defense; AstraZeneca

Terminated

Malignant Pleural Effusion With ZD6474

Lung Cancer | Pleural Effusion

United States
Fujirebio Diagnostics, Inc.

Terminated

Multiple Biomarkers in Undiagnosed Pleural Effusion

Pleural Effusion, Malignant | Pleural Effusion

United States
University of California, Davis

Completed

The First Therapeutic Intervention in Malignant Pleural Effusion Trial (TIME-1)

Pleural Effusion | Malignant Pleural Effusion

United States
University of Pennsylvania

Terminated

Rapid Pleurodesis Through an Indwelling Pleural Catheter (RAPID)

Pleural Diseases | Pleural Effusion, Malignant | Pleurodesis

United States
University of Virginia
National Cancer Institute (NCI)

Completed

Surgery and Intrapleural Docetaxel in Treating Patients With Malignant Pleural Effusion

Metastatic Cancer

United States
University of Pennsylvania
National Cancer Institute (NCI); Biogen

Completed

Gene Therapy for Pleural Malignancies

Pleural Mesothelioma | Metastatic Pleural Effusions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Standard Chest Tube Compared With a Small Catheter in Treating Malignant Pleural Effusion in Patients With Cancer

Metastatic Cancer | Pulmonary Complications

United States
National Cancer Institute (NCI)

Withdrawn

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Malignant Pleural Mesotheliomas (Mpm) | Malignant Pleural Effusions (Mpe) | Epithelial Tumors, Malignant | Pleural Effusions, Malignant | Mesothelin (Msln)

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Identifying Early Lung Cancer Cells in Malignant Pleural Effusion Samples From Patients With Primary Lung Cancer

Lung Cancer | Metastatic Cancer

United States
Maimonides Medical Center

Completed

Chest Tube Drainage of Transudative Pleural Effusions Hastens Liberation From Mechanical Ventilation

Liberation From Mechanical Ventilation

United States
UNC Lineberger Comprehensive Cancer Center
Amgen; CareFusion

Terminated

A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion

Lung Cancer | Malignant Pleural Effusion | Stage IV Metastatic Cancer

United States
Allegheny Singer Research Institute (also known...

Recruiting

Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer (RIOT2)

Malignant Ascites | Malignant Pleural Effusion

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Impact of Pleural Manometry on Chest Discomfort After Therapeutic Thoracentesis

Pleural Effusion

United States
M.D. Anderson Cancer Center

Recruiting

GRAvity- Versus Wall Suction-drIven Large Volume Thoracentesis: a rAndomized Controlled Study (GRAWITAS Study)

Pulmonary Edema | Pleural Effusions, Chronic | Thoracentesis

United States
Vanderbilt University Medical Center

Completed

Gravity- Versus Suction-driven Large Volume Thoracentesis (GRAVITAS)

Pleural Effusion

United States
Memorial Healthcare System
Genentech, Inc.

Completed

Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis

Pleural Effusion

United States
University of Minnesota

Completed

Thoracentesis QI Study

Pleural Effusion

United States
M.D. Anderson Cancer Center

Recruiting

EXPAREL or Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Catheter Placement

Malignant Pleural Neoplasm

United States
Yale University

Completed

The Safety of Thoracentesis, Tunneled Pleural Catheter, and Chest Tubes in Patients Taking Novel Oral Anti-Coagulants

Pleural Effusion | Thoracic Effusion

United States
Guy's and St Thomas' NHS Foundation Trust

Completed

Malignant Pleural Effusions: Evaluating the psYchosocial Impact of Indwelling Pleural Catheters on Patients (MY-IPC)

Malignant Pleural Effusion | Indwelling Pleural Catheter

United Kingdom
Kaiser Permanente
Genentech, Inc.

Terminated

Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy

Pleural Effusion

United States
UNC Lineberger Comprehensive Cancer Center

Recruiting

UNC Pleural Fluid Registry

Breast Cancer | Lung Cancer | Empyema | Malignant Pleural Effusion | Lung Infection

United States
Icahn School of Medicine at Mount Sinai

Recruiting

Erector Spinae Plane Block With Bupivacaine for Medical Thoracoscopy

Postoperative Pain | Pleural Disease

United States
University of California, Davis

Completed

Drainage Amount for Removal of Thoracostomy Tube (DARTT)

Pneumothorax | Pleural Effusion

United States
National Cancer Institute (NCI)

Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Malignant Pleural Mesotheliomas NOS | Esophageal Cancers NOS | Lung Cancer NOS | Thoracic Cancers | Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura

United States
CareFusion

Completed

Safety and Effectiveness of a New Pleural Catheter for Symptomatic, Recurrent, MPEs Versus Approved Pleural Catheter (SWIFT)

Malignant Pleural Effusion

United States, United Kingdom
CareFusion

Completed

A Pilot Study Evaluating the Safety and Effectiveness of a New Pleural Catheter for the Medical Management of Symptomatic, Recurrent, Malignant Pleural Effusions

Malignant Pleural Effusions

United Kingdom
Northumbria Healthcare NHS Foundation Trust
Rocket Medical plc

Recruiting

Interventions for Malignant Pleural Effusions Impact on Fatigue (IMPE-F)

Malignant Pleural Effusion

United Kingdom
Memorial Sloan Kettering Cancer Center
Genelux Corporation

Active, not recruiting

Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma

Lung Cancer

United States
University of Oxford

Completed

Using Thoracic Ultrasound to Predict Pleurodesis Success in Malignant Pleural Effusions: a Pilot Study

Malignant Pleural Effusion

United Kingdom
Gloucestershire Hospitals NHS Foundation Trust

Unknown

The Experiences of Patients Living With Malignant Pleural Effusions

Malignant Pleural Effusion

United Kingdom
Peter Bushunow MD
Novartis Pharmaceuticals

Terminated

Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung Cancer (ZAP)

Non Small Cell Lung Cancer | Malignant Pleural Effusion

United States
Washington University School of Medicine

Completed

Catheter Placement for Hepatic Hydrothorax

Pleural Effusion

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

HPPH and PDT for Pleural Malignancy

Pleural Malignancy

United States
Deep Breeze

Completed

Vibration Response Imaging (VRI) in Management and Evaluation in Patients With Pleural Effusion

Pleural Effusion

United States
Candel Therapeutics, Inc.
University of Pennsylvania

Completed

Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion (MpeTK01)

Breast Cancer | Ovarian Cancer | Lung Cancer | Mesothelioma | Malignant Pleural Effusion

United States
Duke University
CareFusion

Completed

Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter (ASAP)

Pleural Effusion, Malignant

United States

Clinical Trials on Pleural Diseases in United States

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