Clinical Trials on Primary Myelofibrosis in Ireland

Total 1519 results

Novartis Pharmaceuticals

Completed

Panobinostat and Ruxolitinib in Primary Myelofibrosis, Post-polycythemia Vera-myelofibrosis or Post-essential Thrombocythemia-myelofibrosis

Idiopathic Myelofibrosis | Post Essential Thrombocythemia Myelofibrosis | Post Polycythemia-Vera Myelofibrosis

United Kingdom, Ireland, Germany, Italy, France
Actuate Therapeutics Inc.

Completed

Actuate 1901: 9-ING-41 in Myelofibrosis

Myelofibrosis

United States
Celgene

Completed

A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence

Primary Myelofibrosis | Anemia

United States, France, Italy, United Kingdom
Celgene

Recruiting

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions (INDEPENDENCE)

Primary Myelofibrosis | Myeloproliferative Disorders | Anemia | Myelofibrosis | Post-Polycythemia Vera Myelofibrosis

France, Belgium, Austria, Spain, Australia, Canada, Japan, United States, Korea, Republic of, Romania, Israel, Italy, China, Czechia, Germany, Greece, Ireland, Poland, United Kingdom, Hong Kong, Hungary, Lebanon, Colombia, Argentina, Chile and more
Sanofi

Completed

Phase III Study of SAR302503 in Intermediate-2 and High Risk Patients With Myelofibrosis (JAKARTA)

Hematopoietic Neoplasm

Austria, Germany, Italy, Spain, United Kingdom, France, Belgium, Israel, Sweden, Australia, United States, Lithuania, Portugal, Korea, Republic of, Singapore, Taiwan, Mexico, Brazil, Canada, Hungary, Ireland, Poland, Romania, Russian... and more
Sierra Oncology, Inc.

Completed

Momelotinib Versus Ruxolitinib in Subjects With Myelofibrosis (Simplify 1)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States, France, Germany, Spain, Israel, Bulgaria, Romania, Japan, Taiwan, Korea, Republic of, Australia, Belgium, Canada, Netherlands, Singapore, Poland, Hungary, Denmark, Sweden, United Kingdom, Czechia, Austria
Queen's University, Belfast
Mayo Clinic; University Hospital Southampton NHS Foundation Trust; University... and other collaborators

Completed

Myeloproliferative Neoplasms: an In-depth Case-control Study (MOSAICC)

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia

United Kingdom
Incyte Corporation

Completed

Myelofibrosis and Essential Thrombocythemia Observational Study (MOST)

MPN (Myeloproliferative Neoplasms)

United States, Puerto Rico
Novartis Pharmaceuticals

Completed

INC424 for Patients With Primary Myelofibrosis, Post Polycythemia Myelofibrosis or Post-essential Thrombocythemia Myelofibrosis. (JUMP)

Myelofibrosis

Belgium, Colombia, Canada, Italy, Spain, Austria, Germany, Czechia, Thailand, Hungary, Greece, Argentina, Brazil, Israel, Russian Federation, Mexico, Portugal, South Africa, Tunisia, Slovakia, Saudi Arabia, Poland, Algeria, Ireland, Mor...
CTI BioPharma

Terminated

Pacritinib Versus Best Available Therapy to Treat Patients With Myelofibrosis and Thrombocytopenia (PAC326)

Primary Myelofibrosis | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

United States, Canada, France, United Kingdom, Australia, Belgium, Germany, New Zealand, Netherlands, Russian Federation, Hungary, Czechia
University of Ulster
DSM Ltd; Public Health Agency (Northern Ireland)

Recruiting

Optimal Nutrition for Prevention of Hypertension in Pregnancy (OptiPREG)

Pregnancy | Blood Pressure

Ireland, United Kingdom
Celgene

Recruiting

Connect® Myeloid Disease Registry

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Primary Myelofibrosis

United States, Puerto Rico
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Active, not recruiting

An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib (FREEDOM2)

Primary Myelofibrosis | Myelofibrosis | Post-Polycythemia Vera

Australia, Austria, Belgium, China, Czechia, France, Germany, Hungary, Italy, Korea, Republic of, Netherlands, Poland, Russian Federation, Spain, Ireland, United Kingdom
Novartis Pharmaceuticals

Completed

A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF

Bone Marrow Diseases | Hematologic Diseases | Blood Coagulation Disorders | Hemorrhagic Disorders | Primary Myelofibrosis | Myeloproliferative Disorders | Polycythemia Vera | Thrombocytosis | Essential Thrombocythemia | Blood Platelet Disorders

United Kingdom, Belgium, Canada, France, Australia, Netherlands, Spain, Denmark, Ireland, Italy, Germany
Mr HD Flood

Unknown

Botulinum Toxin in the Treatment of Idiopathic Detrusor Overactivity

Overactive Detrusor

Ireland
Belfast Health and Social Care Trust

Completed

Investigating the Effect of Intravenous and Oral Tranexamic Acid on Blood Loss After Primary Hip and Knee Arthroplasty (TRAC-24)

Primary Total Hip Arthroplasty | Primary Total Knee Arthroplasty

United Kingdom
National University of Ireland, Galway, Ireland
Health Research Board, Ireland

Completed

Supporting the Improvement and Management of Prescribing for Urinary Tract Infections (SIMPle) (SIMPle)

Uncomplicated Urinary Tract Infection

Ireland
Merrion Fertility Clinic
University College Dublin

Unknown

Cervical Mucus - the Biochemical and Molecular Properties in Fertile and Subfertile Women (C-MIS Study) (C-MIS)

Infertility

Ireland
National University of Ireland, Galway, Ireland
Enterprise Ireland

Completed

Evaluating a Digital Intervention for Overactive Bladder

Overactive Bladder

Ireland
University of Limerick

Completed

Feasibility Study of Transcutaneous Tibial Nerve Stimulation for Urinary Symptoms in People With Multiple Sclerosis

Multiple Sclerosis | Urinary Bladder, Overactive | Lower Urinary Tract Symptoms | Urinary Incontinence | Urinary Bladder, Neurogenic | Urinary Incontinence, Urge | Nocturia | Bladder Dysfunction | Neurogenic Bladder Dysfunction | Urinary Frequency More Than Once at Night

Ireland
Cliodhna Browne

Completed

Strategies to Maximise Patient Comfort During ESWL

Nephrolithiasis

Ireland
Astellas Pharma Europe Ltd.

Completed

Vesitirim™ in Men Postmarketing Observational Study (VIM)

Overactive Bladder (OAB) | Lower Urinary Tract Symptoms (LUTS)

Ireland
Merrion Fertility Clinic
University College Dublin

Unknown

Cervical Surgery and the Fertility Effect (c-SAFE) (c-SAFE)

Infertility

Ireland
University College Hospital Galway

Completed

Early Post-operative Removal of Urethral Catheter in Patients Undergoing Colorectal Surgery With Epidural Analgesia

Urinary Retention

Ireland
The Adelaide and Meath Hospital, incorporating...

Unknown

LAParoscopic Entry Technique in REnal Surgery (LAPRES)

Kidney Diseases

Ireland
University College Cork

Completed

The Effect of a Musical Intervention on Stress Response to Venepuncture

Pain | Stress, Physiological

Ireland
University College Dublin
Health Research Board, Ireland; National Maternity Hospital, Ireland; Irish Blood...

Not yet recruiting

Study Comparing Platelet Transfusion Volumes in Premature Babies (PlaNeT-3)

Thrombocytopenia | Transfusion

Ireland
University College Hospital Galway
National University of Ireland, Galway, Ireland; Health Research Board, Ireland

Completed

Sodium Intake in Chronic Kidney Disease (STICK) (STICK)

Kidney Diseases | Renal Insufficiency, Chronic | Renal Insufficiency

Ireland
Mid Western Regional Hospital, Ireland

Unknown

Preconditioning Against Renal Damage Under Contrast Examination (Re-DUCE-F)

Acute Kidney Injury

Ireland
Newtricious R&D BV

Completed

Effect of NWT-03 on Blood Pressure

Blood Pressure | Albuminuria

Ireland
Cancer Trials Ireland

Unknown

Study of Blood and Urine Samples in Patients With Newly Diagnosed Localized Prostate Cancer Treated With Hormone Therapy and Radiation Therapy. ICORG 06-15

Prostate Cancer

Ireland
University College Hospital Galway
National University of Ireland, Galway, Ireland; European Research Council

Completed

Clarifying Optimal Sodium Intake Project (COSIP-1)

Hypertension | Cardiovascular Disease | Blood Pressure | Kidney Disease

Ireland
University College Cork

Active, not recruiting

Microbiome Establishment in Preterm Infants (PIMENTO)

Microbial Colonization | Prematurity

Ireland
Cancer Trials Ireland

Recruiting

Breast Cancer Proteomics and Molecular Heterogeneity

Primary Breast Cancer | Recurrent/Metastatic Breast Cancer

Ireland
University College Cork

Completed

Management of Nausea and Vomiting of Pregnancy (DIM)

Nausea | Vomiting | Pregnancy | Hyperemesis Gravidarum

Ireland
University College Cork
Science Foundation Ireland

Unknown

Learning to Evaluate Blood Pressure at Home (LEANBH) (LEANBH)

Hypertension in Pregnancy

Ireland
Mid Western Regional Hospital, Ireland

Completed

Can Remote Ischaemic Preconditioning Reduce Contrast Induced Nephropathy in Patients Receiving Contrast for Computed Tomography? (CT RIPC CIN)

Contrast Induced Nephropathy | Remote Ischaemic Preconditioning

Ireland
The Adelaide and Meath Hospital, incorporating...

Unknown

Local Anaesthetic and Steroid in the Ureter (LASTE)

Pain, Postoperative | Ureter Stone

Ireland
Cancer Trials Ireland

Completed

Comparing Two Sets of Bladder-Filling Instructions in Treating Patients Undergoing Radiation Therapy For Prostate Cancer. ICORG 05-04

Prostate Cancer

Ireland
Cancer Trials Ireland

Completed

Biomarkers of Response to Taxotere in HRPC. ICORG 08-08, V2

Prostate Cancer | Metastatic Cancer

Ireland
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Evaluate The Clinical Effectiveness, Safety And Tolerability Of Sildenafil Used In Doses ≥20mg TID For The Treatment Of Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Germany, Ireland
University College Dublin
University of Copenhagen; Rush University Medical Center

Recruiting

Semaglutide's Efficacy in Achieving Weight Loss for Those With HIV (SWIFT)

Obesity | HIV-1-infection

Ireland
University College Cork
Health Research Board, Ireland; Health Research Board - Trials Methodology...

Completed

Enhancing Men's Awareness of Testicular Diseases (E-MAT): A Feasibility Trial (E-MAT)

Testicular Diseases

Ireland
GlaxoSmithKline

Completed

A Study On Concentrations Of 16448 In Blood And The Safety Of This Compound In Healthy Males With Premature Ejaculation

Premature Ejaculation

Ireland
University College Dublin

Recruiting

Placing Preterm Infants in Polyethylene Bags Immediately After Birth

Hypothermia | Infant | Newborn | Premature

Ireland
Mid Western Regional Hospital, Ireland

Unknown

RCT to Evaluate the Renal Protective Effects of Remote Ischaemic Preconditioning in Peripheral Angioplasty

Peripheral Vascular Disease

Ireland
Karl Neff
University College Dublin

Completed

The Effect of Glucagon-like-peptide 1 (GLP-1) Receptor Agonism on Diabetic Kidney Disease

Diabetic Kidney Disease

Ireland
Cancer Trials Ireland

Active, not recruiting

A Prospective Phase II Dose Escalation Study Using IMRT for High Risk N0 M0 Prostate Cancer. ICORG 08-17

Prostate Cancer

Ireland
University College Cork
Osypka Medical, Berlin, Germany

Terminated

Non-invasive Objective Assessment of Hemodynamics in Preterm Neonates (NOAH)

Intraventricular Hemorrhage | Hemodynamic Instability | Hypotension and Shock | Hypoperfusion | Cardiac Function | Circulatory Transition

Ireland
Kira Murphy
Irish Research Council; University of Pittsburgh Medical Center; Waterford Instituate...

Recruiting

A Comparison of Aerobic and Resistance Exercise to Counteract Treatment Side Effects in Men With Prostate Cancer

Exercise | Prostate Cancer

Ireland

Clinical Trials on Primary Myelofibrosis in Ireland

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