Clinical Trials on Refractory Malignant Brain Neoplasm

Total 14167 results

City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Molecular Genetics Studies of Cancer Patients and Their Relatives

Malignant Neoplasm

United States, Peru, Colombia, Mexico, Puerto Rico
Wake Forest University Health Sciences

Terminated

Developing and Validating Fertilit-e

Malignant Neoplasm

United States
University of Utah

Terminated

Multi-Tracer Positron Emission Tomography in Patients With Solid Tumors

Malignant Neoplasm

United States
Sanofi

Active, not recruiting

Evaluation of SAR408701 in Patients With Advanced Solid Tumors

Neoplasm Malignant

United States, Canada, France, Korea, Republic of, Spain
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Music Therapy Video Development in Improving Communication, Emotional Distress, and Recovery in Adolescents/Young Adults Undergoing Treatment for High-Risk Cancer and Their Parents

Malignant Neoplasm

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Attitudes and Knowledge Regarding Clinical Trials in Underserved Populations Receiving Care at the Comprehensive Cancer Center of Wake Forest University

Malignant Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

FLT-PET in Predicting Response to Chemotherapy in Patients With Advanced Malignancies

Malignant Neoplasm

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Clinical Model in Evaluating Clinical, Psychosocial, and Health Economic Factors in Adolescent and Young Adult Patients With Cancer

Malignant Neoplasm

United States
Roswell Park Cancer Institute

Terminated

Impact of Early Mobility on Post-Surgery Recovery in Patients Undergoing Oncologic Surgeries

Malignant Neoplasm

United States
Sanofi

Completed

Open Label Treatment Extension Study With SAR245408 or SAR245409 as a Monotherapy or as a Combination Regimen

Neoplasm Malignant

Spain, Belgium, United States, France
NatureWise Biotech & Medicals Corporation

Completed

A Safety and Pharmacokinetic Study of NBM-BMX Administered Orally to Patients With Advanced Cancer

Malignant Neoplasm

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Next Generation Sequence Target-Directed Therapy in Treating Patients With Cancer

Malignant Neoplasm

United States
Gary Morrow
National Cancer Institute (NCI)

Completed

Multimedia Psychoeducation or Print Education in Preparing Cancer Patients for Decision Making About Clinical Trials

Malignant Neoplasm

United States
Qilu Puget Sound Biotherapeutics (dba Sound Biologics)
Pharmaceutical Research Associates

Unknown

A Study of PSB205 in Subjects With Advanced Solid Tumors

Neoplasm Malignant

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Conquer Cancer Foundation

Completed

Resistance Training Program and Cardiovascular Exercise in Increasing Muscle Mass in Adolescent and Young Adult Stem Cell Transplant Survivors

Malignant Neoplasm

United States
Jonsson Comprehensive Cancer Center

Terminated

18F-Clofarabine PET/CT in Imaging Cancer Patients Before and After Interventions

Malignant Neoplasm

United States
Li Yu

Unknown

Clinical Study of DC-CIK Cells as a Post-remission Treatment for Malignant Tumors

Malignant Neoplasm

China
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Early Oral Supplementation in Improving Nutritional Status in Patients Undergoing Hematopoietic Stem Cell Transplant

Malignant Neoplasm

United States
Sanofi
Merck KGaA, Darmstadt, Germany

Completed

A Safety and Efficacy Study of SAR405838 and Pimasertib in Cancer Patients

Neoplasm Malignant

Netherlands, France
Sanofi

Completed

Phase I, Dose Escalation of SAR125844 in Asian Solid Tumor Patients (SARMETA)

Neoplasm Malignant

Korea, Republic of, Japan
Sanofi
Regeneron Pharmaceuticals

Completed

A Phase I Study of Aflibercept Plus FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin) in Chinese Patients With Advanced Solid Malignancies

Neoplasm Malignant

China
Sanofi

Completed

Effect of SAR302503 on ECG Activity in Patients With Solid Tumors

Neoplasm Malignant

Belgium, United States
Sanofi
Regeneron Pharmaceuticals

Completed

A Study of Intravenous Aflibercept With Docetaxel in Chinese Patients With Solid Tumors

Neoplasm Malignant

China
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Refractory Diffuse Intrinsic Pontine Glioma | CNS Embryonal Tumor, Not Otherwise Specified

United States
Actuate Therapeutics Inc.

Recruiting

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Neuroblastoma | Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Refractory Cancer | Refractory Neoplasm | Refractory Tumor | Cancer Pediatric | Neuroblastoma Recurrent | Pediatric Lymphoma | Pediatric Meningioma

United States
Center Eugene Marquis

Completed

Positron Emission Tomography (PET) During Radio-chemotherapy to Treat Otorhinolaryngological Cancer (TEmPoRAL)

Locally Advanced Malignant Neoplasm | Malignant Neoplasm of Head and Neck

France
Fachklinik Hornheide an der Universität Münster

Unknown

Efficacy of Chemotherapy Combined With Regional Hypothermia in Advanced Malignant Melanoma Patients With Progressive Soft Tissue Metastases

Advanced Metastastic Malignant Melanoma | Refractory to First-Line Chemotherapy Irresectable Progressive Soft Tissue Metastases

Germany
Erasmus Medical Center

Completed

(68^Ga)-GaPSMA-11 PET/MR-imaging of Malignant Intra-axial Brain Tumors

Malignant Brain Tumors

Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Methylphenidate and Physical Activity to Reduce Cancer Related Fatigue Due to Anti PD1 Immunotherapy

Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm

United States
Dana-Farber Cancer Institute
National Institutes of Health (NIH); Candel Therapeutics, Inc.

Recruiting

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 (rQNestin)

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | Ependymoma | Ganglioglioma | Oligodendroglioma | Malignant Astrocytoma | Anaplastic Oligodendroglioma of Brain (Diagnosis) | Mixed Oligo-Astrocytoma | Pylocytic/Pylomyxoid Astrocytoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis

Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Munich Leukemia Laboratory
Illumina, Inc.

Recruiting

Solving Riddles Through Sequencing (SIRIUS)

Leukemia | Rare Diseases | Refractory Lymphoma | Hematologic Malignancy | Refractory Leukemia | Unknown Primary Tumors

Germany
OHSU Knight Cancer Institute
Oregon Health and Science University

Completed

Use of Virtual Reality Goggles During Chemotherapy Infusion to Reduce Anxiety-Related Symptoms

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm | Malignant Thoracic Neoplasm | Malignant Head and Neck Neoplasm | Malignant Breast Neoplasm

United States
UMC Utrecht

Recruiting

The Cohort for Patient-reported Outcomes, Imaging and Trial Inclusion in Metastatic BRAin Disease (COIMBRA) (COIMBRA)

Brain Metastases, Adult | Brain Neoplasms, Adult, Malignant

Netherlands
Duke University

Terminated

Procedural Outcomes in Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) With and Without Rapid On-Site Evaluation (ROSE) (ROSE)

ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION | Benign and Malignant Mediastinal and Hilar Lymph Nodes Known or Suspected Malignancy

United States
DEKK-TEC, Inc.
National Cancer Institute (NCI); The University of Texas Health Science Center... and other collaborators

Completed

Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors (DM-CHOC-PEN)

Metastatic Malignant Neoplasm to Brain | Primary Brain Tumors

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Nab-Paclitaxel/STI-3031 Complex (AP160-Complex) for the Treatment of Advanced or Metastatic Solid Tumors

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Melanoma

United States
Massachusetts General Hospital

Recruiting

Intraoperative Tumor Margin Identification With ICG Dye Imaging

Malignant Neoplasm | Benign Neoplasm

United States
Curis, Inc.

Recruiting

A Study of CA-4948 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma

Relapsed Primary Central Nervous System Lymphoma | Refractory Hematologic Malignancy | Relapsed Hematologic Malignancy | Refractory Primary Central Nervous System Lymphoma

United States, Spain, France, Czechia, Israel, Italy, Poland
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

T Cells Expressing HER2-specific Chimeric Antigen Receptors(CAR) for Patients With HER2-Positive CNS Tumors (iCAR)

Brain Tumor, Recurrent | Brain Tumor, Refractory

United States
Northwell Health

Recruiting

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Glioblastoma | Brain Cancer | Brain Tumor | GBM | Brain Neoplasm | Brain Neoplasm, Malignant | EGFR Gene Overexpression

United States
University of Cincinnati

Completed

Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors

Solid Tumors | Malignant Neoplasm

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

TQB2928 Injection Combined With Penpulimab in Treatment of Advanced Malignant Tumors.

Advanced Malignant Neoplasm

China
Peking University Cancer Hospital & Institute

Recruiting

Clinical Application of Lutetium [177Lu]-Catalase in Tumor Radionuclide Therapy

Advanced Malignant Neoplasm

China
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Neuropsychological and Behavioral Testing in Younger Patients With Cancer

Childhood Malignant Neoplasm

United States, Canada, Puerto Rico, Australia, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors

Childhood Malignant Neoplasm

United States, Canada, Australia, Puerto Rico, Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

A Survey of Parent/Caregiver Practices on the Storage, Use, and Disposal of Opioids in a Comprehensive Cancer Center

Malignant Neoplasm | Caregiver

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Music in Reducing Distress in Participants With Cancer During Chemotherapy Treatment

Malignant Neoplasm | Caregiver

United States
Thomas Jefferson University

Completed

A Computer-Based System for Symptom Reporting in Patients With Cancer Undergoing Treatment

Malignant Neoplasm | Caregiver

United States
University of Washington
National Cancer Institute (NCI)

Completed

Enhancing Connections Program in Improving Communication Between Patients With Incurable Cancer and Their Children

Advanced Malignant Neoplasm

United States

Clinical Trials on Refractory Malignant Brain Neoplasm

Sponsors and Collaborators

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CROs by country

CROs in Bahamas

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Rare Diseases

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